S C Veasey

Summary

Affiliation: University of Pennsylvania
Country: USA

Publications

  1. ncbi Sleep loss and fatigue in residency training: a reappraisal
    Sigrid Veasey
    Center for Sleep and Respiratory Neurobiology, University of Pennsylvania School of Medicine, Philadelphia, PA 19106, USA
    JAMA 288:1116-24. 2002
  2. ncbi ACGME housestaff duty hours: enforced, yet not delivering rested physicians-in-training
    Sigrid Carlen Veasey
    Sleep Med 8:10-1. 2007
  3. ncbi The effects of trazodone with L-tryptophan on sleep-disordered breathing in the English bulldog
    S C Veasey
    Center for Sleep and Respiratory Neurobiology, Division of Pulmonary and Critical Care, Department of Medicine, School of Medicine University of Pennsylvania, Philadelphia, USA
    Am J Respir Crit Care Med 160:1659-67. 1999
  4. ncbi Insight from animal models into the cognitive consequences of adult sleep-disordered breathing
    Sigrid Veasey
    Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
    ILAR J 50:307-11. 2009
  5. ncbi Physicians' work hours: desperately seeking evidence
    Sigrid Veasey
    University of Pennsylvania, Translational Research Building, Room 2115, 125 South 31st Street, Philadelphia, PA 19104, USA
    Occup Environ Med 64:719-20. 2007
  6. ncbi Sedating, not treating sleep apnea: hit & run in primary care
    Sigrid C Veasey
    Center for Sleep and Respiratory Neurobiology, University of Pennsylvania, Philadelphia, PA 19104, USA
    J Clin Sleep Med 1:372-3. 2005
  7. ncbi Medical therapy for obstructive sleep apnea: a review by the Medical Therapy for Obstructive Sleep Apnea Task Force of the Standards of Practice Committee of the American Academy of Sleep Medicine
    Sigrid C Veasey
    Center for Sleep Respiratory Neurobiology, University of Pennsylvania, 972 Maloney Building, 3600 Spruce Street, Philadelphia, PA 19104, USA
    Sleep 29:1036-44. 2006
  8. ncbi Long-term intermittent hypoxia: reduced excitatory hypoglossal nerve output
    Sigrid C Veasey
    Center for Sleep and Respiratory Neurobiology, Division of Sleep Medicine, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia 19104, USA
    Am J Respir Crit Care Med 170:665-72. 2004
  9. ncbi Murine Multiple Sleep Latency Test: phenotyping sleep propensity in mice
    Sigrid C Veasey
    Center for Sleep and Respiratory Neurobiology, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Sleep 27:388-93. 2004
  10. ncbi Long-term intermittent hypoxia in mice: protracted hypersomnolence with oxidative injury to sleep-wake brain regions
    Sigrid C Veasey
    Center for Sleep and Respiratory Neurobiology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Sleep 27:194-201. 2004

Research Grants

  1. Upper Airway Nerve Injury in Apnea: BIP-CHOP-SIRT1 Crosstalk
    Sigrid C Veasey; Fiscal Year: 2010
  2. Intermittent Hypoxia: Mechanisms of Hypersomnolence
    Sigrid Veasey; Fiscal Year: 2009
  3. Intermittent Hypoxia: Mechanisms of Hypersomnolence
    Sigrid Veasey; Fiscal Year: 2007
  4. DIFFERENTIAL VULNERABILITY TO MORBIDITIES OF SLEEP APNEA
    Sigrid Veasey; Fiscal Year: 2003
  5. Sleep Apnea: Upper Airway Nerve Injury
    Sigrid Veasey; Fiscal Year: 2009

Detail Information

Publications20

  1. ncbi Sleep loss and fatigue in residency training: a reappraisal
    Sigrid Veasey
    Center for Sleep and Respiratory Neurobiology, University of Pennsylvania School of Medicine, Philadelphia, PA 19106, USA
    JAMA 288:1116-24. 2002
    ..A more complete understanding of the issues of sleep loss during residency training can inform innovative strategies to minimize the effects of sleepiness and fatigue on patient care and resident safety...
  2. ncbi ACGME housestaff duty hours: enforced, yet not delivering rested physicians-in-training
    Sigrid Carlen Veasey
    Sleep Med 8:10-1. 2007
  3. ncbi The effects of trazodone with L-tryptophan on sleep-disordered breathing in the English bulldog
    S C Veasey
    Center for Sleep and Respiratory Neurobiology, Division of Pulmonary and Critical Care, Department of Medicine, School of Medicine University of Pennsylvania, Philadelphia, USA
    Am J Respir Crit Care Med 160:1659-67. 1999
    ..02. Trazodone with L-tryptophan can treat sleep-disordered breathing (SDB) in an animal model of OSAHS; the effectiveness of this therapy may be related to increased upper airway dilator activity in sleep and/or enhanced slow-wave sleep...
  4. ncbi Insight from animal models into the cognitive consequences of adult sleep-disordered breathing
    Sigrid Veasey
    Department of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA
    ILAR J 50:307-11. 2009
    ..Researchers are poised to use this knowledge to develop pharmacotherapies that may prevent or partially reverse neural injury from sleep apnea...
  5. ncbi Physicians' work hours: desperately seeking evidence
    Sigrid Veasey
    University of Pennsylvania, Translational Research Building, Room 2115, 125 South 31st Street, Philadelphia, PA 19104, USA
    Occup Environ Med 64:719-20. 2007
  6. ncbi Sedating, not treating sleep apnea: hit & run in primary care
    Sigrid C Veasey
    Center for Sleep and Respiratory Neurobiology, University of Pennsylvania, Philadelphia, PA 19104, USA
    J Clin Sleep Med 1:372-3. 2005
  7. ncbi Medical therapy for obstructive sleep apnea: a review by the Medical Therapy for Obstructive Sleep Apnea Task Force of the Standards of Practice Committee of the American Academy of Sleep Medicine
    Sigrid C Veasey
    Center for Sleep Respiratory Neurobiology, University of Pennsylvania, 972 Maloney Building, 3600 Spruce Street, Philadelphia, PA 19104, USA
    Sleep 29:1036-44. 2006
    ....
  8. ncbi Long-term intermittent hypoxia: reduced excitatory hypoglossal nerve output
    Sigrid C Veasey
    Center for Sleep and Respiratory Neurobiology, Division of Sleep Medicine, Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia 19104, USA
    Am J Respir Crit Care Med 170:665-72. 2004
    ..Similar alterations in neurochemical responsiveness may occur in select persons with obstructive sleep apnea...
  9. ncbi Murine Multiple Sleep Latency Test: phenotyping sleep propensity in mice
    Sigrid C Veasey
    Center for Sleep and Respiratory Neurobiology, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Sleep 27:388-93. 2004
    ....
  10. ncbi Long-term intermittent hypoxia in mice: protracted hypersomnolence with oxidative injury to sleep-wake brain regions
    Sigrid C Veasey
    Center for Sleep and Respiratory Neurobiology, University of Pennsylvania School of Medicine, Philadelphia, PA 19104, USA
    Sleep 27:194-201. 2004
    ....
  11. ncbi Serotonin agonists and antagonists in obstructive sleep apnea: therapeutic potential
    Sigrid C Veasey
    Department of Medicine, Center for Sleep and Respiratory Neurobiology, University of Pennsylvania, Hospital of the University of Pennsylvania, Philadelphia, Pennsylvania 19104 4283, USA
    Am J Respir Med 2:21-9. 2003
    ..However, with continued effort to elucidate the pharmacology of neurochemical control of state-dependent changes in respiratory control, the availability of pharmacological therapy for this disorder is not too far away...
  12. ncbi Molecular and physiologic basis of obstructive sleep apnea
    Sigrid Carlen Veasey
    Division of Sleep Medicine, University of Pennsylvania School of Medicine, 3600 Spruce Street, Philadelphia, PA 19104, USA
    Clin Chest Med 24:179-93. 2003
    ..An improved understanding of the mechanisms through which OSAHS progresses may lead to alternative therapies and aid in the identification of persons at risk for disease progression...
  13. ncbi An automated system for recording and analysis of sleep in mice
    S C Veasey
    Center for Sleep and Respiratory Neurobiology, University of Pennsylvania, School of Medicine, Philadelphia 19104 4283, USA
    Sleep 23:1025-40. 2000
    ..An experimental protocol is suggested for acquiring baseline sleep data for genetic studies. This sleep recording protocol, scoring, and analysis system is designed to facilitate the understanding of genetic basis of sleep structure...
  14. ncbi The effects of ondansetron on sleep-disordered breathing in the English bulldog
    S C Veasey
    Center for Sleep and Respiratory Neurobiology, Department of Medicine, School of Medicine, University of Pennsylvania, 19104 4283, USA
    Sleep 24:155-60. 2001
    ..These data suggest a therapeutic potential for ondansetron in obstructive sleep-disordered breathing, particularly REM sleep apnea...
  15. ncbi Treatment of obstructive sleep apnoea
    Sigrid Veasey
    Center for Sleep and Respiratory Neurobiology and Department of Medicine, University of Pennsylvania School of Medicine, Philadelphia, PA, USA
    Indian J Med Res 131:236-44. 2010
    ..With a strong partnership, obstructive sleep apnoea may be effectively treated in growing numbers of patients...
  16. ncbi Hypoglossal nerve response to 5-HT3 drugs injected into the XII nucleus and vena cava in the rat
    P Fenik
    Department of Medicine, School of Medicine, and Center for Sleep and Respiratory Neurobiology, University of Pennsylvania, Philadelphia 19104-4283, USA
    Sleep 24:871-8. 2001
    ..These results highlight the importance of understanding serotonergic effects on respiratory drive outside the UAWD motor nuclei as we search for 5-HT drug therapies for OSDB...
  17. ncbi Single cell laser dissection with molecular beacon polymerase chain reaction identifies 2A as the predominant serotonin receptor subtype in hypoglossal motoneurons
    G Zhan
    Center for Sleep and Respiratory Neurobiology, 972 Maloney Building, 3600 Spruce Street, Philadelphia, PA 19104, USA
    Neuroscience 113:145-54. 2002
    ..This information will allow a more complete understanding of serotonergic control of respiratory activity...
  18. ncbi Pharmacotherapies for obstructive sleep apnea: how close are we?
    S C Veasey
    Division of Sleep Medicine and Pulmonary, Department of Medicine, University of Pennsylvania, School of Medicine, Philadelphia, Pennsylvania 19104 4283, USA
    Curr Opin Pulm Med 7:399-403. 2001
    ..We are currently well poised to develop effective pharmacotherapies for obstructive sleep apnea, with opportunities to target several regions involved in respiratory control...
  19. ncbi Obstructive sleep apnea: re-evaluating our index of severity
    Sigrid Carlen Veasey
    Sleep Med 7:5-6. 2006
  20. ncbi Will we ever have an effective pharmacotherapy for obstructive sleep apnea?
    Sigrid Carlen Veasey
    Sleep 28:18-9. 2005

Research Grants15

  1. Upper Airway Nerve Injury in Apnea: BIP-CHOP-SIRT1 Crosstalk
    Sigrid C Veasey; Fiscal Year: 2010
    ..The proposed studies are designed to identify novel pathways for therapies to prevent and/or reverse the injuries. ..
  2. Intermittent Hypoxia: Mechanisms of Hypersomnolence
    Sigrid Veasey; Fiscal Year: 2009
    ....
  3. Intermittent Hypoxia: Mechanisms of Hypersomnolence
    Sigrid Veasey; Fiscal Year: 2007
    ....
  4. DIFFERENTIAL VULNERABILITY TO MORBIDITIES OF SLEEP APNEA
    Sigrid Veasey; Fiscal Year: 2003
    ..Therefore, this work provides an essential foundation for determining gene function in the susceptibility of sleepiness, impaired cognation and behavioral responses caused by obstructive sleep apnea. (End of Abstract.) ..
  5. Sleep Apnea: Upper Airway Nerve Injury
    Sigrid Veasey; Fiscal Year: 2009
    ..Collectively, the proposed studies will unveil important mechanisms of neuronal injury in obstructive sleep apnea and should reveal diabetes is a risk factor for this neural injury in sleep apnea. ..