T L Vaughan

Summary

Affiliation: University of Washington
Country: USA

Publications

  1. pmc GST, NAT1, CYP1A1 polymorphisms and risk of esophageal and gastric adenocarcinomas
    Louise Wideroff
    Applied Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, EPN 4005, 6130 Executive Boulevard, MSC 7344, Bethesda, MD 20892 7344, USA
    Cancer Detect Prev 31:233-6. 2007
  2. pmc The role of tobacco, alcohol, and obesity in neoplastic progression to esophageal adenocarcinoma: a prospective study of Barrett's esophagus
    Sheetal Hardikar
    Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
    PLoS ONE 8:e52192. 2013
  3. pmc Occupational exposure to formaldehyde and wood dust and nasopharyngeal carcinoma
    T L Vaughan
    Program in Epidemiology MP 474, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave, PO Box 19024, Seattle WA 98109, USA
    Occup Environ Med 57:376-84. 2000
  4. ncbi Non-steroidal anti-inflammatory drugs and risk of neoplastic progression in Barrett's oesophagus: a prospective study
    Thomas L Vaughan
    Public Health Sciences Division, Fred Hutchinson Cancer Research Centre, Seattle, WA 98109, USA
    Lancet Oncol 6:945-52. 2005
  5. ncbi Nonsteroidal anti-inflammatory drug use, body mass index, and anthropometry in relation to genetic and flow cytometric abnormalities in Barrett's esophagus
    Thomas L Vaughan
    Program in Epidemiology T L V, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA
    Cancer Epidemiol Biomarkers Prev 11:745-52. 2002
  6. ncbi Gastroesophageal reflux disease, use of H2 receptor antagonists, and risk of esophageal and gastric cancer
    D C Farrow
    Fred Hutchinson Cancer Research Center, and University of Washington, School of Public Health and Community Medicine, Department of Epidemiology, Seattle 98109 1024, USA
    Cancer Causes Control 11:231-8. 2000
  7. ncbi Diet and nasopharyngeal cancer in a low-risk population
    D C Farrow
    Program in Epidemiology, Fred Hutchinson Cancer Research Center, and Department of Epidemiology, University of Washington, Seattle, USA
    Int J Cancer 78:675-9. 1998
  8. ncbi Family history of cancer and risk of esophageal and gastric cancers in the United States
    P K Dhillon
    Program in Epidemiology, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
    Int J Cancer 93:148-52. 2001
  9. ncbi Association of Chlamydia pneumoniae immunoglobulin A seropositivity and risk of lung cancer
    L A Jackson
    Department of Epidemiology, School of Public Health and Community Medicine, University of Washington, Seattle, USA
    Cancer Epidemiol Biomarkers Prev 9:1263-6. 2000
  10. ncbi Carbonated soft drink consumption and risk of esophageal adenocarcinoma
    Susan T Mayne
    Department of Epidemiology and Public Health, Yale University School of Medicine and Cancer Center, New Haven, CT 06520 8034, USA
    J Natl Cancer Inst 98:72-5. 2006

Collaborators

Detail Information

Publications33

  1. pmc GST, NAT1, CYP1A1 polymorphisms and risk of esophageal and gastric adenocarcinomas
    Louise Wideroff
    Applied Research Program, Division of Cancer Control and Population Sciences, National Cancer Institute, EPN 4005, 6130 Executive Boulevard, MSC 7344, Bethesda, MD 20892 7344, USA
    Cancer Detect Prev 31:233-6. 2007
    ..In a population-based case-control study, we examined risks in relation to polymorphisms of the following genes: GSTP1; GSTM1; GSTT1; NAT1; and CYP1A1...
  2. pmc The role of tobacco, alcohol, and obesity in neoplastic progression to esophageal adenocarcinoma: a prospective study of Barrett's esophagus
    Sheetal Hardikar
    Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
    PLoS ONE 8:e52192. 2013
    ..No medical, surgical or lifestyle interventions have been proven to safely lower EA risk...
  3. pmc Occupational exposure to formaldehyde and wood dust and nasopharyngeal carcinoma
    T L Vaughan
    Program in Epidemiology MP 474, Fred Hutchinson Cancer Research Center, 1100 Fairview Ave, PO Box 19024, Seattle WA 98109, USA
    Occup Environ Med 57:376-84. 2000
    ..To investigate whether occupational exposures to formaldehyde and wood dust increase the risk of nasopharyngeal cancer (NPC)...
  4. ncbi Non-steroidal anti-inflammatory drugs and risk of neoplastic progression in Barrett's oesophagus: a prospective study
    Thomas L Vaughan
    Public Health Sciences Division, Fred Hutchinson Cancer Research Centre, Seattle, WA 98109, USA
    Lancet Oncol 6:945-52. 2005
    ..We aimed to assess the role of NSAID in the development of oesophageal adenocarcinoma and precursor lesions in people with Barrett's oesophagus--a metaplastic disorder that confers a high risk of oesophageal adenocarcinoma...
  5. ncbi Nonsteroidal anti-inflammatory drug use, body mass index, and anthropometry in relation to genetic and flow cytometric abnormalities in Barrett's esophagus
    Thomas L Vaughan
    Program in Epidemiology T L V, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA
    Cancer Epidemiol Biomarkers Prev 11:745-52. 2002
    ..We also conclude that NSAID use may reduce the risk of progression to cancer in this population. Prospective studies are needed to confirm these results...
  6. ncbi Gastroesophageal reflux disease, use of H2 receptor antagonists, and risk of esophageal and gastric cancer
    D C Farrow
    Fred Hutchinson Cancer Research Center, and University of Washington, School of Public Health and Community Medicine, Department of Epidemiology, Seattle 98109 1024, USA
    Cancer Causes Control 11:231-8. 2000
    ....
  7. ncbi Diet and nasopharyngeal cancer in a low-risk population
    D C Farrow
    Program in Epidemiology, Fred Hutchinson Cancer Research Center, and Department of Epidemiology, University of Washington, Seattle, USA
    Int J Cancer 78:675-9. 1998
    ..Our results indicate that future studies should consider the effects of dietary risk factors on the risk of specific histologic subsets of NPC, and not assume that the disease is etiologically homogeneous...
  8. ncbi Family history of cancer and risk of esophageal and gastric cancers in the United States
    P K Dhillon
    Program in Epidemiology, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
    Int J Cancer 93:148-52. 2001
    ..Our data point to the role of familial susceptibility to gastric cancer, but not to any form of esophageal cancer, in the United States...
  9. ncbi Association of Chlamydia pneumoniae immunoglobulin A seropositivity and risk of lung cancer
    L A Jackson
    Department of Epidemiology, School of Public Health and Community Medicine, University of Washington, Seattle, USA
    Cancer Epidemiol Biomarkers Prev 9:1263-6. 2000
    ..36-13.68) than former smokers (OR 1.50; 95% CI, 0.48-4.75; P for interaction term, 0.26). Additional studies, including prospective serological evaluations, are needed to further assess the possible significance of this association...
  10. ncbi Carbonated soft drink consumption and risk of esophageal adenocarcinoma
    Susan T Mayne
    Department of Epidemiology and Public Health, Yale University School of Medicine and Cancer Center, New Haven, CT 06520 8034, USA
    J Natl Cancer Inst 98:72-5. 2006
    ..These findings indicate that CSD consumption (especially diet CSD) is inversely associated with risk of esophageal adenocarcinoma, and thus it is not likely to have contributed to the rising incidence rates...
  11. ncbi Mutagen sensitivity and neoplastic progression in patients with Barrett's esophagus: a prospective analysis
    Dennis L Chao
    Division of Human Biology, Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, C1 157, Seattle, WA 98109, USA
    Cancer Epidemiol Biomarkers Prev 15:1935-40. 2006
    ....
  12. pmc NSAIDs modulate CDKN2A, TP53, and DNA content risk for progression to esophageal adenocarcinoma
    Patricia C Galipeau
    Human Biology Division, Fred Hutchinson Cancer Research Center, Seattle, Washington, United States of America
    PLoS Med 4:e67. 2007
    ..We aimed to evaluate somatic genetic abnormalities with NSAIDs as predictors of EA in a prospective cohort study of patients with BE...
  13. ncbi Alcohol dehydrogenase 3 and risk of esophageal and gastric adenocarcinomas
    Mary Beth Terry
    Mailman School of Public Health, Department of Epidemiology, Columbia University, 722 West 168th Street, Room 724A, New York, NY 10032, USA
    Cancer Causes Control 18:1039-46. 2007
    ..The alcohol dehydrogenase gene has several polymorphisms which may lead to faster conversion of ethanol to acetaldehyde, which may increase cancer risk...
  14. ncbi Central adiposity and risk of Barrett's esophagus
    Zoe R Edelstein
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington, USA
    Gastroenterology 133:403-11. 2007
    ..Aside from chronic reflux, the etiology of Barrett's esophagus (BE) remains largely unknown. This case-control study investigated body mass index (BMI), central adiposity, and cigarette smoking and risk of BE...
  15. ncbi Longitudinal study of insulin-like growth factor, insulin-like growth factor binding protein-3, and their polymorphisms: risk of neoplastic progression in Barrett's esophagus
    Sid H Siahpush
    Public Health Sciences Division, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
    Cancer Epidemiol Biomarkers Prev 16:2387-95. 2007
    ..IGF-I and its main binding protein, IGF binding protein-3 (IGFBP-3), and their polymorphisms have been investigated in relation to risk of many cancers, but not esophageal adenocarcinoma...
  16. ncbi Leukocyte telomere length predicts cancer risk in Barrett's esophagus
    Rosa Ana Risques
    Department of Pathology, University of Washington, Seattle, WA 98195 7705, USA
    Cancer Epidemiol Biomarkers Prev 16:2649-55. 2007
    ..Patients and..
  17. pmc Dietary supplement use and risk of neoplastic progression in esophageal adenocarcinoma: a prospective study
    Linda M Dong
    Cancer Prevention Program, Fred Hutchinson Cancer Research Center, and Department of Epidemiology, University of Washington, Seattle, WA 98109, USA
    Nutr Cancer 60:39-48. 2008
    ..10-0.60). In this cohort study, use of multivitamins and single antioxidant supplements was associated with a significantly reduced risk of EA and markers of neoplastic progression among individuals with Barrett's esophagus...
  18. ncbi Low-fat, high fruit and vegetable diets and weight loss do not affect biomarkers of cellular proliferation in Barrett esophagus
    Alan R Kristal
    Fred Hutchinson Cancer Research Center, Cancer Prevention Program, M4 B402, P O Box 19024, Seattle, WA, USA
    Cancer Epidemiol Biomarkers Prev 14:2377-83. 2005
    ..We conclude that substantial dietary change has no short-term effects on biomarkers of cellular proliferation in Barrett esophagus or on clinical observations of the Barrrett segment...
  19. ncbi Demographic and lifestyle predictors of survival in patients with esophageal or gastric cancers
    Katrina F Trivers
    Department of Epidemiology, University of North Carolina at Chapel Hill, CB 7435, Chapel Hill, North Carolina 27599 7435, USA
    Clin Gastroenterol Hepatol 3:225-30. 2005
    ..Risk factors for subtypes of esophageal and gastric cancer recently have been identified, but their effect on survival is unknown...
  20. pmc Serum selenium levels in relation to markers of neoplastic progression among persons with Barrett's esophagus
    Rebecca E Rudolph
    Cancer Prevention and Trials Program, Fred Hutchinson Cancer Research Center, and Department of Medicine, University of Washington, Seattle 98109 1024, USA
    J Natl Cancer Inst 95:750-7. 2003
    ..We used a cross-sectional study to investigate the relationship between serum selenium levels and markers of neoplastic progression among persons with Barrett's esophagus...
  21. ncbi Nonsteroidal anti-inflammatory drug use associated with reduced incidence of adenocarcinomas of the esophagus and gastric cardia that overexpress cyclin D1: a population-based study
    Marilie D Gammon
    University of North Carolina, School of Public Health, Department of Epidemiology, Chapel Hill, North Carolina, USA
    Cancer Epidemiol Biomarkers Prev 13:34-9. 2004
    ..These data suggest that the reduction in risk associated with NSAID use may be restricted to those esophageal and gastric cardia adenocarcinomas that overexpress cyclin D1...
  22. ncbi Population attributable risks of esophageal and gastric cancers
    Lawrence S Engel
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Bethesda, MD, USA
    J Natl Cancer Inst 95:1404-13. 2003
    ..Herein, we estimate the population attributable risks (PARs) for various risk factors observed in a multicenter population-based case-control study...
  23. ncbi Trends in the incidence rates of nasopharyngeal carcinoma among Chinese Americans living in Los Angeles County and the San Francisco metropolitan area, 1992-2002
    Li Min Sun
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
    Am J Epidemiol 162:1174-8. 2005
    ..While the reasons underlying the observed patterns of incidence remain to be determined, changes in lifestyle and environment are likely to be contributory factors...
  24. pmc Food group intake and risk of subtypes of esophageal and gastric cancer
    Stephanie A Navarro Silvera
    Department of Health and Nutrition Sciences, Montclair State University, Montclair, NJ 07043, USA
    Int J Cancer 123:852-60. 2008
    ....
  25. ncbi Sinonasal cancer and occupational exposures: a pooled analysis of 12 case-control studies
    Daniele Luce
    INSERM Unité 88, Hopital, National de Saint Maurice, Saint Maurice, France
    Cancer Causes Control 13:147-57. 2002
    ..In order to examine the associations between sinonasal cancer and occupational exposures other than wood dust and leather dust, the data from 12 case-control studies conducted in seven countries were pooled and reanalyzed...
  26. ncbi A population-based study of glutathione S-transferase M1, T1 and P1 genotypes and risk for lung cancer
    Valle Nazar-Stewart
    Center for Research on Occupational and Environmental Toxicology, Oregon Health and Science University, Portland, OR 97201, USA
    Lung Cancer 40:247-58. 2003
    ..These results support previous reports that the GSTM1 null genotype is associated with a modest increase in risk for lung cancer, particularly among heavy smokers, suggest no role for GSTT1 and the need for further study of GSTP1...
  27. ncbi Glutathione S-transferase M1, T1, and P1 polymorphisms and survival among lung cancer patients
    Carol Sweeney
    Division of Epidemiology, University of Minnesota, Minneapolis, Minnesota 55454, USA
    Cancer Epidemiol Biomarkers Prev 12:527-33. 2003
    ..Future studies of lung cancer survival should take into account GSTM1 genotype as well as investigate underlying mechanisms...
  28. ncbi Gastric fluid bile concentrations and risk of Barrett's esophagus
    Katie S Nason
    Department of Surgery, University of Washington, Seattle, WA, USA
    Interact Cardiovasc Thorac Surg 6:304-7. 2007
    ..Patients with low gastric fluid pH (3-5) may represent a subset of patients at high risk of developing Barrett's esophagus...
  29. ncbi Cigarette smoking and risk of prostate cancer in middle-aged men
    Lora A Plaskon
    Department of Urology, University of Washington, Seattle, USA
    Cancer Epidemiol Biomarkers Prev 12:604-9. 2003
    ..Given that smoking cessation seems to reduce these risks, results from this study have public health ramifications and suggest that prostate cancer should be added to the list of tumors for which cigarette smoking is a risk factor...
  30. ncbi A functional polymorphism of toll-like receptor 4 gene increases risk of gastric carcinoma and its precursors
    Georgina L Hold
    Department of Medicine and Therapeutics, Aberdeen University, Aberdeen, Scotland
    Gastroenterology 132:905-12. 2007
    ..The TLR4+896A>G polymorphism linked with impaired reactivity to bacterial lipopolysaccharide may play a role in gastric carcinogenesis...
  31. ncbi Epidemiology and pathogenesis of esophageal cancer
    Rebecca S Holmes
    Department of Epidemiology, University of Washington School of Public Health and Community Medicine, Seattle, WA, USA
    Semin Radiat Oncol 17:2-9. 2007
    ..Lifestyle changes, such as weight loss and exercise, are additional ways in which the incidence of ACE might be reduced...
  32. ncbi Prior lung disease and risk of lung cancer in a large prospective study
    Alyson J Littman
    Department of Epidemiology, University of Washington, Seattle, WA, USA
    Cancer Causes Control 15:819-27. 2004
    ..Identifying factors that increase a smoker's risk of developing lung cancer may help scientists to better understand the etiology of lung cancer and more effectively target high-risk groups for screening...
  33. ncbi Occupation and risk of esophageal and gastric cardia adenocarcinoma
    Lawrence S Engel
    Occupational Epidemiology Branch, Division of Cancer Epidemiology and Genetics, National Cancer Institute, National Institutes of Health, Bethesda, Maryland 20892, USA
    Am J Ind Med 42:11-22. 2002
    ..Adenocarcinomas of the esophagus and gastric cardia have risen dramatically in incidence over the past few decades, however, little research has been conducted on the occupational risk factors for these cancers...