K A Varady

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint Effects of modified alternate-day fasting regimens on adipocyte size, triglyceride metabolism, and plasma adiponectin levels in mice
    K A Varady
    Department of Nutritional Sciences and Toxicology, University of California at Berkeley, Berkeley, CA 94720, USA
    J Lipid Res 48:2212-9. 2007
  2. ncbi request reprint Alternate-day fasting and chronic disease prevention: a review of human and animal trials
    Krista A Varady
    Department of Nutritional Sciences and Toxicology, University of California at Berkeley, Berkeley, CA 94720 3104, USA
    Am J Clin Nutr 86:7-13. 2007
  3. pmc Modified alternate-day fasting regimens reduce cell proliferation rates to a similar extent as daily calorie restriction in mice
    K A Varady
    Department of Nutritional Sciences and Toxicology, University of California at Berkeley, Morgan Hall, Rm 308, Berkeley, California, 94720 3104, USA
    FASEB J 22:2090-6. 2008
  4. doi request reprint Improvements in body fat distribution and circulating adiponectin by alternate-day fasting versus calorie restriction
    Krista A Varady
    Department of Nutritional Sciences and Toxicology, University of California at Berkeley, Berkeley, CA 94720, USA
    J Nutr Biochem 21:188-95. 2010
  5. doi request reprint Alternate-day fasting reduces global cell proliferation rates independently of dietary fat content in mice
    Krista A Varady
    Department of Nutritional Sciences and Toxicology, University of California at Berkeley, Berkeley, California, USA
    Nutrition 25:486-91. 2009
  6. ncbi request reprint Dose effects of modified alternate-day fasting regimens on in vivo cell proliferation and plasma insulin-like growth factor-1 in mice
    Krista A Varady
    Department of Nutritional Sciences and Toxicology, University of California at Berkeley, Berkeley, California 94720 3104, USA
    J Appl Physiol 103:547-51. 2007
  7. doi request reprint Do calorie restriction or alternate-day fasting regimens modulate adipose tissue physiology in a way that reduces chronic disease risk?
    Krista A Varady
    Department of Nutritional Sciences and Toxicology, University of California at Berkeley, Berkeley, California 94720 3104, USA
    Nutr Rev 66:333-42. 2008
  8. pmc AdPLA ablation increases lipolysis and prevents obesity induced by high-fat feeding or leptin deficiency
    Kathy Jaworski
    Department of Nutritional Science and Toxicology, 220 Morgan Hall, University of California, Berkeley, California 94720, USA
    Nat Med 15:159-68. 2009
  9. pmc Adipose overexpression of desnutrin promotes fatty acid use and attenuates diet-induced obesity
    Maryam Ahmadian
    Department of Nutritional Science and Toxicology, University of California, Berkeley, California, USA
    Diabetes 58:855-66. 2009
  10. doi request reprint Differential in vivo effects on target pathways of a novel arylpyrazole glucocorticoid receptor modulator compared with prednisolone
    Donald J Roohk
    Department of Nutritional Sciences and Toxicology, 309 Morgan Hall, University of California, Berkeley, CA 94720 3104, USA
    J Pharmacol Exp Ther 333:281-9. 2010

Collaborators

Detail Information

Publications16

  1. ncbi request reprint Effects of modified alternate-day fasting regimens on adipocyte size, triglyceride metabolism, and plasma adiponectin levels in mice
    K A Varady
    Department of Nutritional Sciences and Toxicology, University of California at Berkeley, Berkeley, CA 94720, USA
    J Lipid Res 48:2212-9. 2007
    ..Plasma adiponectin levels were not affected. In summary, modified ADF (ADF-50%) and complete ADF (ADF-100%) regimens modulate adipocyte function, despite there being no change in body weight or adipose tissue weight in the former group...
  2. ncbi request reprint Alternate-day fasting and chronic disease prevention: a review of human and animal trials
    Krista A Varady
    Department of Nutritional Sciences and Toxicology, University of California at Berkeley, Berkeley, CA 94720 3104, USA
    Am J Clin Nutr 86:7-13. 2007
    ..More research is required to establish definitively the consequences of ADF...
  3. pmc Modified alternate-day fasting regimens reduce cell proliferation rates to a similar extent as daily calorie restriction in mice
    K A Varady
    Department of Nutritional Sciences and Toxicology, University of California at Berkeley, Morgan Hall, Rm 308, Berkeley, California, 94720 3104, USA
    FASEB J 22:2090-6. 2008
    ..In summary, modified ADF, allowing the consumption of 15% of energy needs on the restricted intake day, decreases global cell proliferation similarly as true ADF and daily CR without reducing body weight...
  4. doi request reprint Improvements in body fat distribution and circulating adiponectin by alternate-day fasting versus calorie restriction
    Krista A Varady
    Department of Nutritional Sciences and Toxicology, University of California at Berkeley, Berkeley, CA 94720, USA
    J Nutr Biochem 21:188-95. 2010
    ..These findings indicate that ADF (both modified and true) produces similar beneficial modulations in body fat distribution and adiponectin levels as daily CR...
  5. doi request reprint Alternate-day fasting reduces global cell proliferation rates independently of dietary fat content in mice
    Krista A Varady
    Department of Nutritional Sciences and Toxicology, University of California at Berkeley, Berkeley, California, USA
    Nutrition 25:486-91. 2009
    ..Accordingly, we examined the effects of 85% restriction on the fast day (ADF-85%) with an LF or HF background diet on proliferation rates of various tissues...
  6. ncbi request reprint Dose effects of modified alternate-day fasting regimens on in vivo cell proliferation and plasma insulin-like growth factor-1 in mice
    Krista A Varady
    Department of Nutritional Sciences and Toxicology, University of California at Berkeley, Berkeley, California 94720 3104, USA
    J Appl Physiol 103:547-51. 2007
    ..These findings confirm the beneficial effects of ADF-100% on cancer risk by decreasing cell proliferation and IGF-1 levels and suggest that modified ADF regimens comprising 25-50% CR on the fast day do not replicate these effects...
  7. doi request reprint Do calorie restriction or alternate-day fasting regimens modulate adipose tissue physiology in a way that reduces chronic disease risk?
    Krista A Varady
    Department of Nutritional Sciences and Toxicology, University of California at Berkeley, Berkeley, California 94720 3104, USA
    Nutr Rev 66:333-42. 2008
    ..e., adipose tissue morphology, triglyceride metabolism, and adipokine release, and attempts to link these changes to indicators of chronic disease risk...
  8. pmc AdPLA ablation increases lipolysis and prevents obesity induced by high-fat feeding or leptin deficiency
    Kathy Jaworski
    Department of Nutritional Science and Toxicology, 220 Morgan Hall, University of California, Berkeley, California 94720, USA
    Nat Med 15:159-68. 2009
    ..AdPLA is a major regulator of adipocyte lipolysis and is crucial for the development of obesity...
  9. pmc Adipose overexpression of desnutrin promotes fatty acid use and attenuates diet-induced obesity
    Maryam Ahmadian
    Department of Nutritional Science and Toxicology, University of California, Berkeley, California, USA
    Diabetes 58:855-66. 2009
    ..To investigate the role of desnutrin in adipose tissue triacylglycerol (TAG) and fatty acid metabolism...
  10. doi request reprint Differential in vivo effects on target pathways of a novel arylpyrazole glucocorticoid receptor modulator compared with prednisolone
    Donald J Roohk
    Department of Nutritional Sciences and Toxicology, 309 Morgan Hall, University of California, Berkeley, CA 94720 3104, USA
    J Pharmacol Exp Ther 333:281-9. 2010
    ..Because multiple actions can be measured concurrently in a single animal, this method is a powerful systems approach for characterizing and differentiating the effects of ligands that bind nuclear receptors...
  11. doi request reprint Are functional foods redefining nutritional requirements?
    Peter J Jones
    Richardson Centre for Functional Foods and Nutraceuticals, University of Manitoba, 196 Innovation Dr, Winnipeg, MB R3T 6C5
    Appl Physiol Nutr Metab 33:118-23. 2008
    ..Such discrepancies emphasize the need for a more all-encompassing definition of a nutrient requirement; that is, one that moves beyond the prevention of overt deficiency to encompass improved health and disease risk reduction...
  12. ncbi request reprint Effect of plant sterols and exercise training on cholesterol absorption and synthesis in previously sedentary hypercholesterolemic subjects
    Krista A Varady
    School of Dietetics and Human Nutrition, Faculty of Agricultural and Environmental Sciences, McGill University, Montreal, Quebec, Canada
    Transl Res 149:22-30. 2007
    ..25, P=0.03). These findings suggest that exercise does not modulate lipid levels by altering to cholesterol absorption or synthesis, whereas plant sterols favorably alter levels of LDL cholesterol by suppressing intestinal absorption...
  13. ncbi request reprint Effect of weight loss resulting from a combined low-fat diet/exercise regimen on low-density lipoprotein particle size and distribution in obese women
    Krista A Varady
    School of Dietetics and Human Nutrition, McGill University, Montreal, Quebec, Canada, H9X 3V9
    Metabolism 55:1302-7. 2006
    ..In conclusion, these findings suggest that weight loss, resulting from a low-fat diet/exercise program, has only a minimal effect on LDL particle size and distribution...
  14. ncbi request reprint Plant sterols combined with exercise for the treatment of hypercholesterolemia: overview of independent and synergistic mechanisms of action
    Christopher P F Marinangeli
    School of Dietetics and Human Nutrition, McGill University, Quebec, Canada
    J Nutr Biochem 17:217-24. 2006
    ..In sum, the present review lends further insight as to the metabolic benefits of adopting a healthy lifestyle, including plant sterols and endurance training, in the treatment of dyslipidemia...
  15. ncbi request reprint Plant sterols and endurance training combine to favorably alter plasma lipid profiles in previously sedentary hypercholesterolemic adults after 8 wk
    Krista A Varady
    School of Dietetics and Human Nutrition, Faculty of Agricultural and Environmental Sciences, McGill University, Montreal, and the Veterans Hospital, Sainte Anne de Bellevue, Quebec
    Am J Clin Nutr 80:1159-66. 2004
    ..Plant sterol supplementation was shown to reduce total and LDL-cholesterol concentrations, whereas endurance training was shown to increase HDL-cholesterol concentrations and decrease triacylglycerol concentrations...
  16. ncbi request reprint Role of policosanols in the prevention and treatment of cardiovascular disease
    Krista A Varady
    School of Dietetics and Human Nutrition, McGill University, Ste Anne de Bellevue, Quebec, Canada
    Nutr Rev 61:376-83. 2003
    ..In summary, policosanols are a promising resource in the prevention and therapy of cardiovascular disease (CVD), but these results need to be confirmed in independent laboratories...