Russell N Van Gelder

Summary

Affiliation: University of Washington
Country: USA

Publications

  1. doi request reprint Non-visual photoreception: sensing light without sight
    Russell N Van Gelder
    Department of Ophthalmology, University of Washington Medical School, Seattle, Washington, USA
    Curr Biol 18:R38-9. 2008
  2. doi request reprint Cataract surgery in the setting of uveitis
    Russell N Van Gelder
    Department of Ophthalmology, University of Washington Medical School, Seattle, Washington 98195, USA
    Curr Opin Ophthalmol 20:42-5. 2009
  3. doi request reprint Efficacy and potential complications of difluprednate use for pediatric uveitis
    Mark A Slabaugh
    Department of Ophthalmology, University of Washington School of Medicine, Seattle, 98104, USA
    Am J Ophthalmol 153:932-8. 2012
  4. doi request reprint Postcataract surgical inflammation
    Parisa Taravati
    Department of Ophthalmology, University of Washington School of Medicine, Seattle, Washington 98104, USA
    Curr Opin Ophthalmol 23:12-8. 2012
  5. pmc Melanopsin is highly resistant to light and chemical bleaching in vivo
    Timothy J Sexton
    Department of Ophthalmology, University of Washington, Seattle, Washington 98195, USA
    J Biol Chem 287:20888-97. 2012
  6. pmc Melanopsin and mechanisms of non-visual ocular photoreception
    Timothy Sexton
    Departments of Ophthalmology and and Biological Structure, University of Washington School of Medicine, Seattle, Washington 98104, USA
    J Biol Chem 287:1649-56. 2012
  7. pmc Melanopsin-dependent light avoidance in neonatal mice
    Juliette Johnson
    Department of Ophthalmology, University of California, San Francisco, CA 94143, USA
    Proc Natl Acad Sci U S A 107:17374-8. 2010
  8. pmc Timeless genes and jetlag
    Russell N Van Gelder
    Department of Ophthalmology, Washington University Medical School, St Louis, MO 63110, USA
    Proc Natl Acad Sci U S A 103:17583-4. 2006
  9. pmc Pharmacological and rAAV gene therapy rescue of visual functions in a blind mouse model of Leber congenital amaurosis
    Matthew L Batten
    Department of Ophthalmology, University of Washington, Seattle, Washington, United States of America
    PLoS Med 2:e333. 2005
  10. ncbi request reprint Melanopsin-dependent persistence and photopotentiation of murine pupillary light responses
    Yanli Zhu
    Department of Ophthalmology and Visual Sciences, Washington University Medical School, St Louis, Missouri, USA
    Invest Ophthalmol Vis Sci 48:1268-75. 2007

Collaborators

  • Krzysztof Palczewski
  • Mark A Slabaugh
  • Parisa Taravati
  • Juliette Johnson
  • A Sancar
  • Ignacio Provencio
  • S A Kay
  • Susan E Doyle
  • Mark D Rollag
  • E D Herzog
  • WILLIAM SCHWARTZ
  • Michael Menaker
  • Satchidananda Panda
  • Daniel C Tu
  • Matthew L Batten
  • Timothy Sexton
  • Timothy J Sexton
  • Marcin Golczak
  • Yanli Zhu
  • Sarah J Vanvickle-Chavez
  • Serguei V Kozlov
  • Donald U Stone
  • Carol L Thompson
  • Raymond Wee
  • Yiing Lin
  • Ethan Buhr
  • Darcy Denner
  • Maureen P Howell
  • Colin L Stewart
  • Christine M Fitzgerald
  • Louis J Muglia
  • Thomas Shane
  • John B Hogenesch
  • Rachel Wevrick
  • James W Bogenpohl
  • Erich C Strauss
  • Leah A Owens
  • J Brooks Crawford
  • Maureen McCall
  • Todd P Margolis
  • Devron H Char
  • Lauren Anderson
  • Fred Rieke
  • Lyudmila Glushakova
  • Elon B Slutsky
  • Li Zhu
  • Thuy Doan
  • Yoshikazu Imanishi
  • Dongyang Zhang
  • Timothy E Holy
  • Wolfgang Baehr
  • Jay Demas
  • Jijing Pang
  • William W Hauswirth
  • Alexander R Moise
  • Loredana Quadro
  • Christopher P Selby
  • Max E Gottesman
  • Katherine Lai
  • Janet Lee
  • William S Blaner
  • Gary D Stormo
  • Brian Shimada
  • Lin Gan
  • Lin Wang
  • Aloka Amarakone
  • Therese M Gibler
  • Tarif A Awad
  • Paul H Taghert
  • Mei Han
  • Ana Maria Castrucci

Detail Information

Publications30

  1. doi request reprint Non-visual photoreception: sensing light without sight
    Russell N Van Gelder
    Department of Ophthalmology, University of Washington Medical School, Seattle, Washington, USA
    Curr Biol 18:R38-9. 2008
    ..This system appears to subserve circadian photic entrainment, the pupillary light response, and a number of other aspects of neurophysiology and behavior...
  2. doi request reprint Cataract surgery in the setting of uveitis
    Russell N Van Gelder
    Department of Ophthalmology, University of Washington Medical School, Seattle, Washington 98195, USA
    Curr Opin Ophthalmol 20:42-5. 2009
    ..To describe recent evidence from the literature concerning optimal treatment of cataract in patients with concomitant uveitis...
  3. doi request reprint Efficacy and potential complications of difluprednate use for pediatric uveitis
    Mark A Slabaugh
    Department of Ophthalmology, University of Washington School of Medicine, Seattle, 98104, USA
    Am J Ophthalmol 153:932-8. 2012
    ..To evaluate the clinical effect of topical difluprednate in pediatric patients for treatment of noninfectious uveitis...
  4. doi request reprint Postcataract surgical inflammation
    Parisa Taravati
    Department of Ophthalmology, University of Washington School of Medicine, Seattle, Washington 98104, USA
    Curr Opin Ophthalmol 23:12-8. 2012
    ..To describe the epidemiology, pathogenesis, and recent developments in the diagnosis and management of postcataract surgery inflammation...
  5. pmc Melanopsin is highly resistant to light and chemical bleaching in vivo
    Timothy J Sexton
    Department of Ophthalmology, University of Washington, Seattle, Washington 98195, USA
    J Biol Chem 287:20888-97. 2012
    ..The data support a model in which retinal is continuously covalently bound to melanopsin and may function through a reversible, bistable mechanism...
  6. pmc Melanopsin and mechanisms of non-visual ocular photoreception
    Timothy Sexton
    Departments of Ophthalmology and and Biological Structure, University of Washington School of Medicine, Seattle, Washington 98104, USA
    J Biol Chem 287:1649-56. 2012
    ..This suggests that melanopsin employs a bistable sequential photon absorption mechanism typical of rhabdomeric opsins...
  7. pmc Melanopsin-dependent light avoidance in neonatal mice
    Juliette Johnson
    Department of Ophthalmology, University of California, San Francisco, CA 94143, USA
    Proc Natl Acad Sci U S A 107:17374-8. 2010
    ..These results strongly suggest that light activation of ipRGCs may regulate physiological functions such as sleep/wake cycles in preterm and neonatal infants...
  8. pmc Timeless genes and jetlag
    Russell N Van Gelder
    Department of Ophthalmology, Washington University Medical School, St Louis, MO 63110, USA
    Proc Natl Acad Sci U S A 103:17583-4. 2006
  9. pmc Pharmacological and rAAV gene therapy rescue of visual functions in a blind mouse model of Leber congenital amaurosis
    Matthew L Batten
    Department of Ophthalmology, University of Washington, Seattle, Washington, United States of America
    PLoS Med 2:e333. 2005
    ..One cause of LCA is loss of the enzyme lecithin:retinol acyl transferase (LRAT), which is required for regeneration of the visual photopigment in the retina...
  10. ncbi request reprint Melanopsin-dependent persistence and photopotentiation of murine pupillary light responses
    Yanli Zhu
    Department of Ophthalmology and Visual Sciences, Washington University Medical School, St Louis, Missouri, USA
    Invest Ophthalmol Vis Sci 48:1268-75. 2007
    ..To determine the relative contributions of inner and outer retinal photoreception to the pupillary light response...
  11. pmc Inner retinal photoreception independent of the visual retinoid cycle
    Daniel C Tu
    Department of Ophthalmology and Visual Sciences, Washington University Medical School, St Louis, MO 63110, USA
    Proc Natl Acad Sci U S A 103:10426-31. 2006
    ..These results demonstrate that the melanopsin-dependent ipRGC photocycle is independent of the visual retinoid cycle...
  12. ncbi request reprint Physiologic diversity and development of intrinsically photosensitive retinal ganglion cells
    Daniel C Tu
    Department of Ophthalmology and Visual Sciences, Washington University Medical School, St Louis, Missouri 63110, USA
    Neuron 48:987-99. 2005
    ..These results demonstrate that ipRGCs are the first light-sensitive cells in the retina and suggest previously unappreciated diversity in this cell population...
  13. ncbi request reprint Effect of vitamin A depletion on nonvisual phototransduction pathways in cryptochromeless mice
    Carol L Thompson
    Department of Biochemistry and Biophysics, University of North Carolina School of Medicine, Chapel Hill, North Carolina, USA
    J Biol Rhythms 19:504-17. 2004
    ..These data demonstrate that both cryptochromes and opsins regulate nonvisual photoresponses...
  14. ncbi request reprint Nonvisual photoreception in the chick iris
    Daniel C Tu
    Department of Ophthalmology and Visual Sciences, Washington University Medical School, St Louis, MO 63110 USA
    Science 306:129-31. 2004
    ..These data characterize a non-opsin photoreception mechanism in a vertebrate eye and suggest a conserved photoreceptive role for cryptochromes in vertebrates...
  15. ncbi request reprint Loss of photic entrainment and altered free-running circadian rhythms in math5-/- mice
    Raymond Wee
    Department of Ophthalmology and Visual Sciences, Washington University Medical School, St Louis, Missouri 63110, USA
    J Neurosci 22:10427-33. 2002
    ....
  16. ncbi request reprint Making (a) sense of non-visual ocular photoreception
    Russell N Van Gelder
    Department of Ophthalmology and Visual Sciences, Washington University Medical School, Campus Box 8096, 660 S Euclid Avenue, St Louis, MO 63110, USA
    Trends Neurosci 26:458-61. 2003
    ....
  17. ncbi request reprint Melanopsin is required for non-image-forming photic responses in blind mice
    Satchidananda Panda
    Genomics Institute of the Novartis Research Foundation, 10675 John J Hopkins Drive, San Diego, CA 92121, USA
    Science 301:525-7. 2003
    ..This indicates the importance of both nonvisual and classical visual photoreceptor systems for nonvisual photic responses in mammals...
  18. pmc Influence of the period-dependent circadian clock on diurnal, circadian, and aperiodic gene expression in Drosophila melanogaster
    Yiing Lin
    Department of Genetics, Washington University Medical School, St Louis, MO, 63110, USA
    Proc Natl Acad Sci U S A 99:9562-7. 2002
    ..Thus, the period-dependent circadian clock regulates only a limited set of rhythmically expressed transcripts. Unexpectedly, period regulates basal and light-regulated gene expression to a very broad extent...
  19. ncbi request reprint Reduced pupillary light responses in mice lacking cryptochromes
    Russell N Van Gelder
    Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, 660 South Euclid Avenue, St Louis, MO 63131, USA
    Science 299:222. 2003
  20. ncbi request reprint Pleiotropic effects of cryptochromes 1 and 2 on free-running and light-entrained murine circadian rhythms
    Russell N Van Gelder
    Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St Louis, MO 63110, USA
    J Neurogenet 16:181-203. 2002
    ..These results suggest that, similar to insect cryptochromes, mammalian cryptochromes function pleiotropically in both circadian rhythm generation and in photic entrainment and behavioral responses...
  21. ncbi request reprint Circadian rhythms: in the loop at last
    Russell N Van Gelder
    Department of Ophthalmology and Visual Sciences, Washington University, St Louis, MO 63110, USA
    Science 300:1534-5. 2003
    ..Both the general script and the specific details of the murine and Drosophila circadian pathways are available at Science's Signal Transduction Knowledge Environment Connections Maps...
  22. doi request reprint How the clock sees the light
    Russell N Van Gelder
    Nat Neurosci 11:628-30. 2008
  23. ncbi request reprint The imprinted gene Magel2 regulates normal circadian output
    Serguei V Kozlov
    Cancer and Developmental Biology Laboratory, National Cancer Institute, Frederick, Maryland 21702, USA
    Nat Genet 39:1266-72. 2007
    ....
  24. ncbi request reprint Action spectrum of Drosophila cryptochrome
    Sarah J Vanvickle-Chavez
    Departments of Ophthalmology and Visual Sciences, Washington University Medical School, St Louis, Missouri 63110, USA
    J Biol Chem 282:10561-6. 2007
    ..The conferral of light-dependent degradation on a heterologous protein by fusion to cryptochrome may be a useful tool for probing protein function in cell expression systems...
  25. ncbi request reprint Cryptochromes and inner retinal non-visual irradiance detection
    Russell N Van Gelder
    Department of Ophthalmology and Visual Sciences, Washington University Medical School, CB 8096, 660 S Euclid Avenue, St Louis, MO 63110, USA
    Novartis Found Symp 253:31-42; discussion 42-55, 102-9, 281-4. 2003
    ..These findings suggest a model where either classical photopigments or inner retinal photopigments are sufficient for non-visual irradiance detection...
  26. ncbi request reprint Metaplastic squamous epithelial downgrowth after clear corneal cataract surgery
    Donald U Stone
    Proctor Foundation, University of California San Francisco, San Francisco, CA 94143, USA
    Am J Ophthalmol 142:695-7. 2006
    ..To report a case of metaplastic squamous epithelial downgrowth after cataract surgery...
  27. ncbi request reprint Clean thoughts about dirty genes
    Russell N Van Gelder
    Department of Ophthalmology and Visual Sciences, Washington University Medical School, St Louis, MO 63110, USA
    J Biol Rhythms 19:3-9. 2004
    ..They conclude with a short list of recommendations for researchers working on circadian rhythms in mixed-strain mice...
  28. ncbi request reprint Recent insights into mammalian circadian rhythms
    Russell N Van Gelder
    Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St Louis, MO 63110, USA
    Sleep 27:166-71. 2004
    ..This review is intended as an overview of recent research activity for the interested sleep disorders clinician or researcher...
  29. ncbi request reprint Resetting the clock: Dexras1 defines a path
    Russell N Van Gelder
    Department of Ophthalmology and Visual Sciences, Washington University Medical School, 660 South Euclid Avenue, St Louis, MO 63110, USA
    Neuron 43:603-4. 2004
    ..In this issue of Neuron, Cheng et al. analyze mice lacking Dexras1 (a Ras family GTPase protein) and demonstrate an important role for G(i/o) signaling mediating both photic and nonphotic phase shifts of the circadian clock...
  30. ncbi request reprint Tales from the crypt(ochromes)
    Russell N Van Gelder
    Department of Ophthalmology and Visual Sciences, Washington University School of Medicine, St Louis, MO 63110, USA
    J Biol Rhythms 17:110-20. 2002
    ..The present review summarizes recent research on the functions of cryptochrome in the circadian timekeeping and photic entrainment pathways...