Rachael E Van Pelt

Summary

Affiliation: University of Colorado Health Sciences Center
Country: USA

Publications

  1. ncbi request reprint Contributions of total and regional fat mass to risk for cardiovascular disease in older women
    R E Van Pelt
    Division of Geriatrics Gerontology, Department of Internal Medicine, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Am J Physiol Endocrinol Metab 282:E1023-8. 2002
  2. pmc Insulin secretion and clearance after subacute estradiol administration in postmenopausal women
    Rachael E Van Pelt
    Department of Medicine, Division of Geriatric Medicine, University of Colorado at Denver and Health Sciences, Colorado 80262, USA
    J Clin Endocrinol Metab 93:484-90. 2008
  3. pmc Acute modulation of adipose tissue lipolysis by intravenous estrogens
    Rachael E Van Pelt
    Department of Medicine, Division of Geriatric Medicine, University of Colorado at Denver and Health Sciences Center, 4200 E Ninth Ave, Campus Box B 179, Denver, CO 80262, USA
    Obesity (Silver Spring) 14:2163-72. 2006
  4. pmc Lower-body adiposity and metabolic protection in postmenopausal women
    R E Van Pelt
    Department of Medicine, Division of Geriatric Medicine, University of Colorado at Denver Health Sciences Center, 4200 East Ninth Avenue, Campus Box B 179, Denver, Colorado 80262, USA
    J Clin Endocrinol Metab 90:4573-8. 2005
  5. pmc Intravenous estrogens increase insulin clearance and action in postmenopausal women
    R E Van Pelt
    4200 E Ninth Ave, Box B179, Denver, CO 80262
    Am J Physiol Endocrinol Metab 285:E311-7. 2003
  6. pmc A losing battle: weight regain does not restore weight loss-induced bone loss in postmenopausal women
    KAREN L VILLALON
    Division of Geriatric Medicine, Department of Medicine, University of Colorado Denver, Aurora, Colorado, USA
    Obesity (Silver Spring) 19:2345-50. 2011
  7. pmc A novel index of whole body antilipolytic insulin action
    Rachael E Van Pelt
    Department of Medicine, Division of Geriatric Medicine, University of Colorado Denver, Aurora, Colorado, USA
    Obesity (Silver Spring) 21:E162-5. 2013
  8. pmc Sex differences in the association of thigh fat and metabolic risk in older adults
    Rachael E Van Pelt
    Department of Medicine, Division of Geriatric Medicine, University of Colorado Denver, Aurora, Colorado, USA
    Obesity (Silver Spring) 19:422-8. 2011
  9. pmc Increases in bone mineral density in response to oral dehydroepiandrosterone replacement in older adults appear to be mediated by serum estrogens
    Catherine M Jankowski
    Division of Geriatric Medicine, University of Colorado Denver, mail stop B179, Room 8111, 12631 East 17th Avenue, Aurora, Colorado 80045, USA
    J Clin Endocrinol Metab 93:4767-73. 2008
  10. pmc Oral dehydroepiandrosterone replacement in older adults: effects on central adiposity, glucose metabolism and blood lipids
    Catherine M Jankowski
    Division of Geriatric Medicine, University of Colorado Denver, Aurora, CO 80045 2527, USA
    Clin Endocrinol (Oxf) 75:456-63. 2011

Detail Information

Publications17

  1. ncbi request reprint Contributions of total and regional fat mass to risk for cardiovascular disease in older women
    R E Van Pelt
    Division of Geriatrics Gerontology, Department of Internal Medicine, Washington University School of Medicine, St Louis, Missouri 63110, USA
    Am J Physiol Endocrinol Metab 282:E1023-8. 2002
    ..Thus trunk fat is a strong independent predictor of insulin resistance and dyslipidemia in postmenopausal women, whereas leg fat appears to confer protective effects against metabolic dysfunction...
  2. pmc Insulin secretion and clearance after subacute estradiol administration in postmenopausal women
    Rachael E Van Pelt
    Department of Medicine, Division of Geriatric Medicine, University of Colorado at Denver and Health Sciences, Colorado 80262, USA
    J Clin Endocrinol Metab 93:484-90. 2008
    ..Whether this is due to an effect of estrogen on insulin or glucose metabolism remains unclear...
  3. pmc Acute modulation of adipose tissue lipolysis by intravenous estrogens
    Rachael E Van Pelt
    Department of Medicine, Division of Geriatric Medicine, University of Colorado at Denver and Health Sciences Center, 4200 E Ninth Ave, Campus Box B 179, Denver, CO 80262, USA
    Obesity (Silver Spring) 14:2163-72. 2006
    ..The aim of this study was to determine whether intravenous (IV) conjugated estrogens (EST) acutely enhance the suppression of whole-body or regional subcutaneous adipose tissue (SAT) lipolysis by insulin in postmenopausal women...
  4. pmc Lower-body adiposity and metabolic protection in postmenopausal women
    R E Van Pelt
    Department of Medicine, Division of Geriatric Medicine, University of Colorado at Denver Health Sciences Center, 4200 East Ninth Avenue, Campus Box B 179, Denver, Colorado 80262, USA
    J Clin Endocrinol Metab 90:4573-8. 2005
    ..It has been suggested that the propensity to store fat in the gluteal-femoral region may be cardioprotective...
  5. pmc Intravenous estrogens increase insulin clearance and action in postmenopausal women
    R E Van Pelt
    4200 E Ninth Ave, Box B179, Denver, CO 80262
    Am J Physiol Endocrinol Metab 285:E311-7. 2003
    ..20 mg. kg-1. min-1) and plasma glycerol concentrations were significantly lower (29.4 vs. 35.0 micro mol/l) for EST vs. CON. Our findings suggest that acute CE administration increases insulin clearance and action in postmenopausal women...
  6. pmc A losing battle: weight regain does not restore weight loss-induced bone loss in postmenopausal women
    KAREN L VILLALON
    Division of Geriatric Medicine, Department of Medicine, University of Colorado Denver, Aurora, Colorado, USA
    Obesity (Silver Spring) 19:2345-50. 2011
    ..Future studies are needed to identify effective strategies to prevent bone loss during periods of weight loss...
  7. pmc A novel index of whole body antilipolytic insulin action
    Rachael E Van Pelt
    Department of Medicine, Division of Geriatric Medicine, University of Colorado Denver, Aurora, Colorado, USA
    Obesity (Silver Spring) 21:E162-5. 2013
    ..We evaluated whether an index of antilipolytic insulin action could be derived from readily available insulin and glycerol concentrations obtained during clamps or oral glucose tolerance tests (OGTT)...
  8. pmc Sex differences in the association of thigh fat and metabolic risk in older adults
    Rachael E Van Pelt
    Department of Medicine, Division of Geriatric Medicine, University of Colorado Denver, Aurora, Colorado, USA
    Obesity (Silver Spring) 19:422-8. 2011
    ..The discordance between the DXA and CT results in men is unclear but may be due to sex differences in visceral fat accrual. The mechanisms underlying the protective effect of thigh fat on metabolic risk factors need to be elucidated...
  9. pmc Increases in bone mineral density in response to oral dehydroepiandrosterone replacement in older adults appear to be mediated by serum estrogens
    Catherine M Jankowski
    Division of Geriatric Medicine, University of Colorado Denver, mail stop B179, Room 8111, 12631 East 17th Avenue, Aurora, Colorado 80045, USA
    J Clin Endocrinol Metab 93:4767-73. 2008
    ..Objective: The aims were to determine the effects of DHEA therapy on changes in sex hormones and IGF-I and their associations with changes in BMD...
  10. pmc Oral dehydroepiandrosterone replacement in older adults: effects on central adiposity, glucose metabolism and blood lipids
    Catherine M Jankowski
    Division of Geriatric Medicine, University of Colorado Denver, Aurora, CO 80045 2527, USA
    Clin Endocrinol (Oxf) 75:456-63. 2011
    ..The effects of DHEA replacement on regional tissue composition, glucose metabolism and blood lipid profile in older adults have been inconsistent...
  11. pmc Timing of ibuprofen use and bone mineral density adaptations to exercise training
    Wendy M Kohrt
    Department of Medicine, Division of Geriatric Medicine, University of Colorado Denver, Denver, CO 80045, USA
    J Bone Miner Res 25:1415-22. 2010
    ..This preliminary study suggests that taking NSAIDs after exercise enhances the adaptive response of BMD to exercise, whereas taking NSAIDs before may impair the adaptive response...
  12. doi request reprint Relative contributions of adiposity and muscularity to physical function in community-dwelling older adults
    Catherine M Jankowski
    Department of Medicine, Division of Geriatric Medicine, University of Colorado Denver, Aurora, Colorado, USA
    Obesity (Silver Spring) 16:1039-44. 2008
    ..To determine the relative contributions of adiposity and muscularity to multi-dimensional performance-based and perceived physical function in older adults living independently...
  13. pmc Effects of soy protein isolate and moderate exercise on bone turnover and bone mineral density in postmenopausal women
    Ellen M Evans
    Division of Geriatrics and Nutritional Sciences, Department of Medicine, Washington University School of Medicine, St Louis, MO, USA
    Menopause 14:481-8. 2007
    ..The aim of this study was to assess the independent and additive effects of soy protein isolate (SPI) and moderate-intensity exercise (EX) on bone turnover and bone mineral density (BMD)...
  14. pmc Acute calcium ingestion attenuates exercise-induced disruption of calcium homeostasis
    Daniel W Barry
    Department of Medicine, Division of General Internal Medicine, University of Colorado, Anschutz Medical Campus, Aurora, CO, USA
    Med Sci Sports Exerc 43:617-23. 2011
    ....
  15. ncbi request reprint Effects of dehydroepiandrosterone replacement therapy on bone mineral density in older adults: a randomized, controlled trial
    Catherine M Jankowski
    Health Sciences Center, University of Colorado at Denver, 4200 East Ninth Avenue, Campus Box B179, Denver, CO 80262, USA
    J Clin Endocrinol Metab 91:2986-93. 2006
    ..Declines in DHEAS with aging may contribute to physiological changes that are sex hormone dependent...
  16. pmc Subcutaneous adipose tissue insulin resistance is associated with visceral adiposity in postmenopausal women
    Beret A Casey
    Division of Endocrinology, Diabetes and Metabolism, Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA
    Obesity (Silver Spring) 22:1458-63. 2014
    ..Whole body and subcutaneous adipose tissue (SAT) insulin resistance association with regional fat mass (FM) was determined...
  17. ncbi request reprint Sex hormone suppression reduces resting energy expenditure and {beta}-adrenergic support of resting energy expenditure
    Danielle S Day
    Division of Geriatric Medicine, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
    J Clin Endocrinol Metab 90:3312-7. 2005
    ..14). Suppression of sex hormones to postmenopausal levels by GnRHant reduced REE in young healthy women. These findings suggest that the withdrawal of estrogen and/or progesterone attenuates REE, possibly through a SNS-mediated mechanism...

Research Grants2

  1. ESTROGEN, INSULIN AND REGIONAL LIPOLYSIS IN OLDER WOMEN
    RACHAEL VAN PELT; Fiscal Year: 2006
    ..She and the department will provide Dr. Van Pelt the rich learning environment, resources, and technical guidance necessary to successfully complete her training and career development. ..
  2. Regional fat-re-accumulation following lipectomy in pre- and postmenopausal women
    RACHAEL VAN PELT; Fiscal Year: 2007
    ..These studies are designed to evaluate the effect of femoral lipectomy on regional AT re-accumulation and metabolic disease risk in pre- and postmenopausal women. ..