MARCIAN VAN DORT

Summary

Affiliation: University of Michigan
Country: USA

Publications

  1. ncbi Direct chromatographic resolution and isolation of the four stereoisomers of meta-hydroxyphenylpropanolamine
    M E Van Dort
    Division of Nuclear Medicine, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan 48109 0552, USA
    Chirality 11:684-8. 1999
  2. ncbi Design, synthesis, and pharmacological characterization of 4-[4, 4-dimethyl-3-(4-hydroxybutyl)-5-oxo-2-thioxo-1-imidazolidinyl]- 2-iodobenzonitrile as a high-affinity nonsteroidal androgen receptor ligand
    M E Van Dort
    Division of Nuclear Medicine, Department of Internal Medicine and Department of Human Genetics, The University of Michigan Medical School, Ann Arbor, Michigan 48109 0552, USA
    J Med Chem 43:3344-7. 2000
  3. ncbi Synthesis and structure-activity studies of side-chain derivatized arylhydantoins for investigation as androgen receptor radioligands
    M E Van Dort
    Department of Radiology, The University of Michigan Medical School, Ann Arhor 48109 0552, USA
    Bioorg Med Chem Lett 11:1045-7. 2001
  4. ncbi Radiosynthesis and evaluation of 5-[125I]iodoindol-3-yl-beta-D-galactopyranoside as a beta-galactosidase imaging radioligand
    Marcian E Van Dort
    Department of Radiology, Center for Molecular Imaging, University of Michigan Medical School, Ann Arbor, MI 48109 2200, USA
    Mol Imaging 7:187-97. 2008
  5. ncbi Targeted imaging and therapy of brain cancer using theranostic nanoparticles
    Mahaveer Swaroop Bhojani
    Center for Molecular Imaging, Departments of Radiation Oncology and, and Radiology, University of Michigan, Ann Arbor, Michigan 48109, United States
    Mol Pharm 7:1921-9. 2010
  6. ncbi Synthesis and structure-activity investigation of iodinated arylhydantoins and arylthiohydantoins for development as androgen receptor radioligands
    Marcian E Van Dort
    Division of Nuclear Medicine, Department of Radiology, The University of Michigan Medical School, Ann Arbor, MI 48109 0552, USA
    Bioorg Med Chem Lett 14:5285-8. 2004

Research Grants

  1. NOVEL RADIOTRACERS FOR ANDROGEN RECEPTOR IMAGING
    MARCIAN VAN DORT; Fiscal Year: 2001

Collaborators

Detail Information

Publications6

  1. ncbi Direct chromatographic resolution and isolation of the four stereoisomers of meta-hydroxyphenylpropanolamine
    M E Van Dort
    Division of Nuclear Medicine, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, Michigan 48109 0552, USA
    Chirality 11:684-8. 1999
    ..Subsequent recrystallization of their bitartarate or fumarate salts gave enantiomeric purities >99%...
  2. ncbi Design, synthesis, and pharmacological characterization of 4-[4, 4-dimethyl-3-(4-hydroxybutyl)-5-oxo-2-thioxo-1-imidazolidinyl]- 2-iodobenzonitrile as a high-affinity nonsteroidal androgen receptor ligand
    M E Van Dort
    Division of Nuclear Medicine, Department of Internal Medicine and Department of Human Genetics, The University of Michigan Medical School, Ann Arbor, Michigan 48109 0552, USA
    J Med Chem 43:3344-7. 2000
    ..DTIB represents a new lead for the development of high-affinity radioiodinated AR radioligands...
  3. ncbi Synthesis and structure-activity studies of side-chain derivatized arylhydantoins for investigation as androgen receptor radioligands
    M E Van Dort
    Department of Radiology, The University of Michigan Medical School, Ann Arhor 48109 0552, USA
    Bioorg Med Chem Lett 11:1045-7. 2001
    ..The N-(iodopropenyl) derivative 13 (Ki = 13 nM) is a potential candidate for development as a radioiodinated AR ligand...
  4. ncbi Radiosynthesis and evaluation of 5-[125I]iodoindol-3-yl-beta-D-galactopyranoside as a beta-galactosidase imaging radioligand
    Marcian E Van Dort
    Department of Radiology, Center for Molecular Imaging, University of Michigan Medical School, Ann Arbor, MI 48109 2200, USA
    Mol Imaging 7:187-97. 2008
    ....
  5. ncbi Targeted imaging and therapy of brain cancer using theranostic nanoparticles
    Mahaveer Swaroop Bhojani
    Center for Molecular Imaging, Departments of Radiation Oncology and, and Radiology, University of Michigan, Ann Arbor, Michigan 48109, United States
    Mol Pharm 7:1921-9. 2010
    ..In this article, we will discuss the application of newer theranostic nanoparticles in targeted brain cancer imaging and treatment...
  6. ncbi Synthesis and structure-activity investigation of iodinated arylhydantoins and arylthiohydantoins for development as androgen receptor radioligands
    Marcian E Van Dort
    Division of Nuclear Medicine, Department of Radiology, The University of Michigan Medical School, Ann Arbor, MI 48109 0552, USA
    Bioorg Med Chem Lett 14:5285-8. 2004
    ..71nM<K(i)<11nM) were displayed by arylhydantoins and arylthiohydantoin derivatives containing hydroxybutyl or methyl side-chains. The latter compounds are potential candidates for development as radioiodinated AR ligands...

Research Grants3

  1. NOVEL RADIOTRACERS FOR ANDROGEN RECEPTOR IMAGING
    MARCIAN VAN DORT; Fiscal Year: 2001
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