Judy Van de Water

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Increased midgestational IFN-γ, IL-4 and IL-5 in women bearing a child with autism: A case-control study
    Paula E Goines
    Division of Rheumatology, Allergy and Clinical Immunology, University of California at Davis, 451 Health Sciences Dr, Suite 6510, Davis, CA 95616, USA
    Mol Autism 2:13. 2011
  2. pmc Further characterization of autoantibodies to GABAergic neurons in the central nervous system produced by a subset of children with autism
    Sharifia Wills
    Division of Rheumatology, Allergy and Clinical Immunology, University of California at Davis, 451 Health Sciences Drive, Suite 6510 GBSF, Davis, CA 95616, USA
    Mol Autism 2:5. 2011
  3. pmc Autism: maternally derived antibodies specific for fetal brain proteins
    Daniel Braunschweig
    Division of Rheumatology, Allergy and Clinical Immunology, University of California at Davis, CA, USA
    Neurotoxicology 29:226-31. 2008
  4. doi request reprint Behavioral correlates of maternal antibody status among children with autism
    Daniel Braunschweig
    Division of Rheumatology Allergy and Clinical Immunology, University of California, Davis, 451 E Health Sciences Drive, Suite 6510 GBSF, Davis, CA 95616, USA
    J Autism Dev Disord 42:1435-45. 2012
  5. pmc Autoantibodies to cerebellum in children with autism associate with behavior
    Paula Goines
    Division of Rheumatology, Allergy and Clinical Immunology, University of California at Davis, Davis, CA 95616, United States
    Brain Behav Immun 25:514-23. 2011
  6. pmc Detection of autoantibodies to neural cells of the cerebellum in the plasma of subjects with autism spectrum disorders
    Sharifia Wills
    Division of Rheumatology, Allergy and Clinical Immunology, University of California at Davis, 451 E Health Sciences Drive, Suite 6510 GBSF, Davis, CA 95616, USA
    Brain Behav Immun 23:64-74. 2009
  7. pmc Reduced levels of immunoglobulin in children with autism correlates with behavioral symptoms
    Luke Heuer
    Division of Rheumatology, Allergy and Clinical Immunology, University of California at Davis, Davis, California 95616, USA
    Autism Res 1:275-83. 2008
  8. doi request reprint Maternal autism-associated IgG antibodies delay development and produce anxiety in a mouse gestational transfer model
    Daniel Braunschweig
    Division of Rheumatology Allergy and Clinical Immunology, University of California, Davis, 451 E Health Sciences Drive, Suite 6510 GBSF, Davis, CA 95616, USA
    J Neuroimmunol 252:56-65. 2012
  9. pmc Altered T cell responses in children with autism
    Paul Ashwood
    Department of Medical Microbiology and Immunology, University of California at Davis, CA, USA
    Brain Behav Immun 25:840-9. 2011
  10. pmc Decreased cellular IL-23 but not IL-17 production in children with autism spectrum disorders
    Charity Onore
    Department of Medical Microbiology and Immunology, University of California at Davis, USA
    J Neuroimmunol 216:126-9. 2009

Collaborators

Detail Information

Publications27

  1. pmc Increased midgestational IFN-γ, IL-4 and IL-5 in women bearing a child with autism: A case-control study
    Paula E Goines
    Division of Rheumatology, Allergy and Clinical Immunology, University of California at Davis, 451 Health Sciences Dr, Suite 6510, Davis, CA 95616, USA
    Mol Autism 2:13. 2011
    ..abstract:..
  2. pmc Further characterization of autoantibodies to GABAergic neurons in the central nervous system produced by a subset of children with autism
    Sharifia Wills
    Division of Rheumatology, Allergy and Clinical Immunology, University of California at Davis, 451 Health Sciences Drive, Suite 6510 GBSF, Davis, CA 95616, USA
    Mol Autism 2:5. 2011
    ..abstract:..
  3. pmc Autism: maternally derived antibodies specific for fetal brain proteins
    Daniel Braunschweig
    Division of Rheumatology, Allergy and Clinical Immunology, University of California at Davis, CA, USA
    Neurotoxicology 29:226-31. 2008
    ....
  4. doi request reprint Behavioral correlates of maternal antibody status among children with autism
    Daniel Braunschweig
    Division of Rheumatology Allergy and Clinical Immunology, University of California, Davis, 451 E Health Sciences Drive, Suite 6510 GBSF, Davis, CA 95616, USA
    J Autism Dev Disord 42:1435-45. 2012
    ..05). This study provides evidence of multiple patterns of reactivity to fetal brain proteins by maternal antibodies associated with ASD and specific childhood behavioral outcomes...
  5. pmc Autoantibodies to cerebellum in children with autism associate with behavior
    Paula Goines
    Division of Rheumatology, Allergy and Clinical Immunology, University of California at Davis, Davis, CA 95616, United States
    Brain Behav Immun 25:514-23. 2011
    ..Future studies are needed to determine the identities of the protein targets and explore their significance in autism...
  6. pmc Detection of autoantibodies to neural cells of the cerebellum in the plasma of subjects with autism spectrum disorders
    Sharifia Wills
    Division of Rheumatology, Allergy and Clinical Immunology, University of California at Davis, 451 E Health Sciences Drive, Suite 6510 GBSF, Davis, CA 95616, USA
    Brain Behav Immun 23:64-74. 2009
    ....
  7. pmc Reduced levels of immunoglobulin in children with autism correlates with behavioral symptoms
    Luke Heuer
    Division of Rheumatology, Allergy and Clinical Immunology, University of California at Davis, Davis, California 95616, USA
    Autism Res 1:275-83. 2008
    ..To assay if plasma antibody levels in children with autism or developmental delays (DD) differ from those with typical development as an indicator of immune function and to correlate antibody levels with severity of behavioral symptoms...
  8. doi request reprint Maternal autism-associated IgG antibodies delay development and produce anxiety in a mouse gestational transfer model
    Daniel Braunschweig
    Division of Rheumatology Allergy and Clinical Immunology, University of California, Davis, 451 E Health Sciences Drive, Suite 6510 GBSF, Davis, CA 95616, USA
    J Neuroimmunol 252:56-65. 2012
    ..This report demonstrates for the first time the effects of a single, low dose gestational exposure of IgG derived from individual MAU on their offspring's physical and social development...
  9. pmc Altered T cell responses in children with autism
    Paul Ashwood
    Department of Medical Microbiology and Immunology, University of California at Davis, CA, USA
    Brain Behav Immun 25:840-9. 2011
    ..Further longitudinal analyzes of cellular immunity profiles would delineate the relationship between immune dysfunction and the progression of behavioral and developmental changes throughout the course of this disorder...
  10. pmc Decreased cellular IL-23 but not IL-17 production in children with autism spectrum disorders
    Charity Onore
    Department of Medical Microbiology and Immunology, University of California at Davis, USA
    J Neuroimmunol 216:126-9. 2009
    ..Decreased cellular IL-23 production in ASD warrants further research to determine its role on the generation and survival of T(H)17 cells, a cell subset important in neuroinflammatory conditions that may include ASD...
  11. pmc Elevated plasma cytokines in autism spectrum disorders provide evidence of immune dysfunction and are associated with impaired behavioral outcome
    Paul Ashwood
    Department of Medical Microbiology and Immunology, University of California, Davis, CA, USA
    Brain Behav Immun 25:40-5. 2011
    ..The characterization of immunological parameters in ASD has important implications for diagnosis, and should be considered when designing therapeutic strategies to treat core symptoms and behavioral impairments of ASD...
  12. ncbi request reprint Brief report: plasma leptin levels are elevated in autism: association with early onset phenotype?
    Paul Ashwood
    Department of Medical Microbiology and Immunology, University of California at Davis, Davis, CA 95616, USA
    J Autism Dev Disord 38:169-75. 2008
    ..042), TD controls (p<.0015), and DD controls (p<.004). We demonstrated an increase in leptin levels in autism, a finding driven by the early onset group...
  13. ncbi request reprint Brain-specific autoantibodies in the plasma of subjects with autistic spectrum disorder
    Maricel Cabanlit
    Division of Rheumatology, Allergy and Clinical Immunology, UC Davis, Davis, CA 95616, USA
    Ann N Y Acad Sci 1107:92-103. 2007
    ..While the potential role of these autoantibodies in AU is currently unknown, their presence suggests a loss of self-tolerance to one or more neural antigens during early childhood...
  14. pmc Correlations of gene expression with blood lead levels in children with autism compared to typically developing controls
    Yingfang Tian
    Department of Neurology, University of California at Davis, Sacramento, CA 95817, USA
    Neurotox Res 19:1-13. 2011
    ..We postulate that this may relate to the underlying genetic differences between the two groups, though other explanations cannot be excluded...
  15. pmc Preliminary evidence of the in vitro effects of BDE-47 on innate immune responses in children with autism spectrum disorders
    Paul Ashwood
    Department of Medical Microbiology and Immunology, University of California, Davis, CA 95616, USA
    J Neuroimmunol 208:130-5. 2009
    ..Moreover, PBMC from the ASD subjects were differentially affected when compared with the TD controls suggesting a biological basis for altered sensitivity to BDE-47 in the ASD population...
  16. pmc Decreased levels of total immunoglobulin in children with autism are not a result of B cell dysfunction
    Luke S Heuer
    Division of Rheumatology, Allergy and Clinical Immunology, University of California at Davis, USA
    J Neuroimmunol 251:94-102. 2012
    ..Results suggest no differences in the B cell parameters measured, indicating that decreased Ig in autism is not a result of B cell dysfunction and other immune cells might be involved...
  17. pmc Maternal and fetal antibrain antibodies in development and disease
    Elizabeth Fox
    Department of Internal Medicine, University of California, Davis, Davis, California 95616, USA
    Dev Neurobiol 72:1327-34. 2012
    ..2009]: Nat Med 15:91-96). In this review, we will discuss the current state of research in the area of maternal autoantibodies and the development of autism...
  18. pmc Maternal autoantibodies are associated with abnormal brain enlargement in a subgroup of children with autism spectrum disorder
    Christine Wu Nordahl
    The M I N D Institute, University of California at Davis, School of Medicine, Sacramento, CA 95817, USA Department of Psychiatry and Behavioral Sciences, University of California at Davis, School of Medicine, Sacramento, CA 95817, USA Electronic address
    Brain Behav Immun 30:61-5. 2013
    ..These results suggest that maternal autoantibodies associated with autism spectrum disorder may impact brain development leading to abnormal enlargement...
  19. pmc Immunologic and neurodevelopmental susceptibilities of autism
    Isaac N Pessah
    School of Veterinary Medicine, University of California, Davis, CA 95616, USA
    Neurotoxicology 29:532-45. 2008
    ....
  20. ncbi request reprint Autoantibodies in autism spectrum disorders (ASD)
    Sharifia Wills
    Division of Rheumatology, Allergy and Clinical Immunology, UC Davis, Davis, CA 95616, USA
    Ann N Y Acad Sci 1107:79-91. 2007
    ..In addition, we will discuss recent studies performed by our group concerning the presence of autoantibodies directed against neural antigens, which are observed in patients with ASD...
  21. pmc MECP2 promoter methylation and X chromosome inactivation in autism
    Raman P Nagarajan
    Medical Microbiology and Immunology and Rowe Program in Human Genetics, University of California, Davis, CA 95616, USA
    Autism Res 1:169-78. 2008
    ..These results suggest that the aberrant MECP2 methylation in autism brain DNA samples is due to locus-specific rather than global X chromosome methylation changes...
  22. doi request reprint Immune-mediated disorders among women carriers of fragile X premutation alleles
    Tri Indah Winarni
    Medical Investigation of Neurodevelopmental Disorders Institute, University of California, Davis, Health System, Sacramento, USA
    Am J Med Genet A 158:2473-81. 2012
    ..4 times higher when compared to carriers without FXPOI (95% CI 1.1-5.0; P = 0.021). The likelihood of IMD in carriers with or without FXPOI is greater (OR 2.4, 95% CI 1.1-5.0; P = 0.021) compared to that of controls...
  23. doi request reprint Immune dysfunction in autism: a pathway to treatment
    Milo Careaga
    Department of Medical Microbiology and Immunology, University of California at Davis, Sacramento, California 95817, USA
    Neurotherapeutics 7:283-92. 2010
    ..A better understanding of the involvement of the immune response in autism, and of how early brain development is altered, may have important therapeutic implications...
  24. pmc Biliary apotopes and anti-mitochondrial antibodies activate innate immune responses in primary biliary cirrhosis
    Ana Lleo
    Division of Rheumatology, Allergy, and Clinical Immunology, University of California at Davis, Davis, CA, USA
    Hepatology 52:987-98. 2010
    ..They further emphasize the critical role of the innate immune system in the perpetuation of this autoimmune disease...
  25. pmc The immune system's role in the biology of autism
    Paula Goines
    Division of Rheumatology, Allergy and Clinical Immunology, University of California at Davis, California, USA
    Curr Opin Neurol 23:111-7. 2010
    ..This body of literature has expanded dramatically over the past few years as researchers continue to identify immune anomalies in individuals with autism...
  26. doi request reprint Breaking boundaries in neural-immune interactions
    A Kimberley McAllister
    Center for Neuroscience, One Shields Avenue, University of California, Davis, Davis, CA 95616, USA
    Neuron 64:9-12. 2009
    ..For the past 60 years, the central nervous system has been considered immunologically privileged. Yet results from diverse fields show clear and convincing evidence of bidirectional communication between the nervous and immune systems...
  27. pmc The CHARGE study: an epidemiologic investigation of genetic and environmental factors contributing to autism
    Irva Hertz-Picciotto
    Division of Epidemiology, Department of Public Health Sciences, School of Medicine, and Medical Investigations of Neurodevelopmental Disorders MIND Institute, University of California Davis, Davis, California, USA
    Environ Health Perspect 114:1119-25. 2006
    ....