Research Topics
Genomes and GenesSpecies | Victor ValcourSummaryAffiliation: University of California Country: USA Publications
Research Grants
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Detail Information
Publications
Pathogenesis of HIV in the central nervous systemVictor Valcour
Memory and Aging Center, University of California San Francisco, 94143 1207, USA
Curr HIV/AIDS Rep 8:54-61. 2011..This review highlights recent investigations of HIV-related CNS injury with emphasis on cART-era neuropathological mechanisms in the context of both US and international settings...- Insulin resistance and cognition among HIV-infected and HIV-uninfected adult women: the Women's Interagency HIV StudyVictor Valcour
Memory and Aging Center, Department of Neurology and Division of Geriatric Medicine, Department of Medicine, University of California at San Francisco, 350 Parnassus Avenue, San Francisco, CA 94143, USA
AIDS Res Hum Retroviruses 28:447-53. 2012..HIV status did not appear to substantially impact the relationship of HOMA with SCN. There was a small but statistically significant association of HOMA and reduced neuropsychological performance on the SCN test in this cohort of women... - Central nervous system viral invasion and inflammation during acute HIV infectionVictor Valcour
Memory and Aging Center, Department of Neurology and Division of Geriatric Medicine, Department of Medicine, University of California San Francisco, CA 94143, USA
J Infect Dis 206:275-82. 2012..Understanding the earliest central nervous system (CNS) events during human immunodeficiency virus (HIV) infection is crucial to knowledge of neuropathogenesis, but these have not previously been described in humans... - The Effects of Age and HIV on Neuropsychological PerformanceVictor Valcour
Memory and Aging Center, Department of Neurology and Division of Geriatric Medicine Department of Medicine, University of California at San Francisco, San Francisco, California 94143, USA
J Int Neuropsychol Soc 17:190-5. 2011..We conclude that older age does not significantly influence neuropsychological performance among HIV patients when seronegative controls are largely composed of individuals from a similar socioeconomic background... - A case of enteroviral meningoencephalitis presenting as rapidly progressive dementiaVictor Valcour
Department of Neurology, Memory and Aging Center, University of California, San Francisco, CA94143, USA
Nat Clin Pract Neurol 4:399-403. 2008..He had hypophonic speech and had mildly increased axial tone. He scored 5 out of 30 on the Mini Mental State Examination and was admitted for expedited evaluation... - Screening for cognitive impairment in human immunodeficiency virusVictor Valcour
Memory and Aging Center, Department of Neurology, University of California San Francisco, USA
Clin Infect Dis 53:836-42. 2011..We describe the clinical presentation of HAND, review existing data related to screening tools, and provide preliminary and practical recommendations in the absence of more definitive studies... - Effects of hepatitis C and HIV on cognition in women: data from the Women's Interagency HIV StudyHoward Crystal
Department of Neurology, SUNY Downstate Medical Center, Brooklyn, NY 11203, USA
J Acquir Immune Defic Syndr 59:149-54. 2012..To compare neuropsychological scores in women infected with HIV, women infected with both HIV and hepatitis C, and uninfected subjects... - Associations of cardiovascular variables and HAART with cognition in middle-aged HIV-infected and uninfected womenHoward A Crystal
Department of Neurology, SUNY Downstate Medical Center, Brooklyn, NY 11203, USA
J Neurovirol 17:469-76. 2011..In this cross-sectional study, we could detect neither positive nor negative effects of HAART on cognition... 
Small-vessel vascular disease in human immunodeficiency virus infection: the Hawaii aging with HIV cohort studyAaron McMurtray
Department of Medicine, John A Burns School of Medicine, University of Hawaii, Honolulu, Hawaii 96816, USA
Cerebrovasc Dis 24:236-41. 2007..This study is designed to determine the relationship between age and occurrence of cerebral manifestations of small-vessel ischemic vascular disease in human immunodeficiency virus (HIV)-seropositive individuals...- Regional cortical thinning associated with detectable levels of HIV DNAKalpana J Kallianpur
Hawaii Center for AIDS, Department of Medicine, University of Hawaii, Honolulu, 96816, USA
Cereb Cortex 22:2065-75. 2012..The areas of reduced cortical thickness are key nodes in cognitive and emotional processing networks and may be etiologically important in HIV-related neurological deficits... - A C17T polymorphism in the mu opiate receptor is associated with quantitative measures of drug use in African American womenHoward A Crystal
Department of Neurology, SUNY Downstate Medical Center, Brooklyn, NY 11203, USA
Addict Biol 17:181-91. 2012..1 (P = 0.02), 2.4 (P = 0.0004), 2.0 (P = 0.03) and 1.9 (P = 0.07). We conclude that the TT genotype of OPRM1 may increase the risk of substance use and abuse... 
Deficits in Self-Awareness Impact the Diagnosis of Asymptomatic Neurocognitive Impairment in HIVStephanie Chiao
1 School of Medicine, University of California San Francisco, San Francisco, California
AIDS Res Hum Retroviruses 29:949-56. 2013..These findings have important implications for use of self-report of function in the diagnosis of HIV-associated neurocognitive disorders (HAND), likely underestimating symptomatic impairment...- Incident neuropathy in HIV-infected patients on HAARTBeau K Nakamoto
Hawaii Center for AIDS, Department of Medicine, John A Burns School of Medicine, University of Hawaii, Honolulu, Hawaii, USA
AIDS Res Hum Retroviruses 26:759-65. 2010..However, current or prior history of d-drug treatment is not a significant risk factor for incident DSP in subjects who had previously tolerated d-drug treatment without developing a toxic DSP... - Neuropsychological test profile differences between young and old human immunodeficiency virus-positive individualsNed Sacktor
Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
J Neurovirol 13:203-9. 2007..These differences could be a result of advanced age itself or age-associated comorbidities such as coexisting cerebrovascular or neurodegenerative disease... - Management of human immunodeficiency virus infection in advanced ageMeredith Greene
Division of Geriatric Medicine, Department of Medicine, University of California, San Francisco, CA, USA
JAMA 309:1397-405. 2013..Human immunodeficiency virus (HIV)-positive patients treated with antiretroviral therapy now have increased life expectancy and develop chronic illnesses that are often seen in older HIV-negative patients... - Impact of HIV and aging on neuropsychological functionLauren A Wendelken
Department of Neurology, UCSF, San Francisco, CA 94143 1207, USA
J Neurovirol 18:256-63. 2012..This review summarizes knowledge of cognition in HIV as it relates to age and presents some emerging controversies...
Research Grants
- Peripheral Reservoir of HIV DNA in Monocytes Pivotal to Cognition in HIVVictor Valcour; Fiscal Year: 2010..Understanding why this happens will allow us to find better ways to prevent or treat this devastating complication of HIV. ..
- Neurodevelopment and Imaging among HIV-infected Children from the PREDICT studyVictor Valcour; Fiscal Year: 2010..Our findings may have an enormous impact on worldwide treatment recommendations. ..