Victor Valcour

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Pathogenesis of HIV in the central nervous system
    Victor Valcour
    Memory and Aging Center, University of California San Francisco, 94143 1207, USA
    Curr HIV/AIDS Rep 8:54-61. 2011
  2. pmc Change in brain magnetic resonance spectroscopy after treatment during acute HIV infection
    Napapon Sailasuta
    Huntington Medical Research Institutes, Pasadena, CA, USA
    PLoS ONE 7:e49272. 2012
  3. pmc HIV DNA reservoir increases risk for cognitive disorders in cART-naïve patients
    Victor G Valcour
    Memory and Aging Center, Department of Neurology, University of California San Francisco, San Francisco, California, USA
    PLoS ONE 8:e70164. 2013
  4. pmc Insulin resistance and cognition among HIV-infected and HIV-uninfected adult women: the Women's Interagency HIV Study
    Victor Valcour
    Memory and Aging Center, Department of Neurology and Division of Geriatric Medicine, Department of Medicine, University of California at San Francisco, 350 Parnassus Avenue, San Francisco, CA 94143, USA
    AIDS Res Hum Retroviruses 28:447-53. 2012
  5. pmc Central nervous system viral invasion and inflammation during acute HIV infection
    Victor Valcour
    Memory and Aging Center, Department of Neurology and Division of Geriatric Medicine, Department of Medicine, University of California San Francisco, CA 94143, USA
    J Infect Dis 206:275-82. 2012
  6. pmc Screening for cognitive impairment in human immunodeficiency virus
    Victor Valcour
    Memory and Aging Center, Department of Neurology, University of California San Francisco, USA
    Clin Infect Dis 53:836-42. 2011
  7. pmc A case of enteroviral meningoencephalitis presenting as rapidly progressive dementia
    Victor Valcour
    Department of Neurology, Memory and Aging Center, University of California, San Francisco, CA94143, USA
    Nat Clin Pract Neurol 4:399-403. 2008
  8. pmc The Effects of Age and HIV on Neuropsychological Performance
    Victor Valcour
    Memory and Aging Center, Department of Neurology and Division of Geriatric Medicine Department of Medicine, University of California at San Francisco, San Francisco, California 94143, USA
    J Int Neuropsychol Soc 17:190-5. 2011
  9. pmc Effects of hepatitis C and HIV on cognition in women: data from the Women's Interagency HIV Study
    Howard Crystal
    Department of Neurology, SUNY Downstate Medical Center, Brooklyn, NY 11203, USA
    J Acquir Immune Defic Syndr 59:149-54. 2012
  10. pmc Peripheral blood HIV DNA is associated with atrophy of cerebellar and subcortical gray matter
    Kalpana J Kallianpur
    Department of Medicine, Hawaii Center for AIDS, University of Hawaii, Honolulu, HI, USA
    Neurology 80:1792-9. 2013

Detail Information

Publications21

  1. pmc Pathogenesis of HIV in the central nervous system
    Victor Valcour
    Memory and Aging Center, University of California San Francisco, 94143 1207, USA
    Curr HIV/AIDS Rep 8:54-61. 2011
    ..This review highlights recent investigations of HIV-related CNS injury with emphasis on cART-era neuropathological mechanisms in the context of both US and international settings...
  2. pmc Change in brain magnetic resonance spectroscopy after treatment during acute HIV infection
    Napapon Sailasuta
    Huntington Medical Research Institutes, Pasadena, CA, USA
    PLoS ONE 7:e49272. 2012
    ..We used MRS to measure brain changes during the first weeks following HIV infection and in response to antiretroviral therapy (ART)...
  3. pmc HIV DNA reservoir increases risk for cognitive disorders in cART-naïve patients
    Victor G Valcour
    Memory and Aging Center, Department of Neurology, University of California San Francisco, San Francisco, California, USA
    PLoS ONE 8:e70164. 2013
    ..These reservoirs remain present despite cART. The objective of this study was to determine if the level of HIV DNA in CD14(+) enriched monocytes predicted cognitive impairment and brain injury...
  4. pmc Insulin resistance and cognition among HIV-infected and HIV-uninfected adult women: the Women's Interagency HIV Study
    Victor Valcour
    Memory and Aging Center, Department of Neurology and Division of Geriatric Medicine, Department of Medicine, University of California at San Francisco, 350 Parnassus Avenue, San Francisco, CA 94143, USA
    AIDS Res Hum Retroviruses 28:447-53. 2012
    ..HIV status did not appear to substantially impact the relationship of HOMA with SCN. There was a small but statistically significant association of HOMA and reduced neuropsychological performance on the SCN test in this cohort of women...
  5. pmc Central nervous system viral invasion and inflammation during acute HIV infection
    Victor Valcour
    Memory and Aging Center, Department of Neurology and Division of Geriatric Medicine, Department of Medicine, University of California San Francisco, CA 94143, USA
    J Infect Dis 206:275-82. 2012
    ..Understanding the earliest central nervous system (CNS) events during human immunodeficiency virus (HIV) infection is crucial to knowledge of neuropathogenesis, but these have not previously been described in humans...
  6. pmc Screening for cognitive impairment in human immunodeficiency virus
    Victor Valcour
    Memory and Aging Center, Department of Neurology, University of California San Francisco, USA
    Clin Infect Dis 53:836-42. 2011
    ..We describe the clinical presentation of HAND, review existing data related to screening tools, and provide preliminary and practical recommendations in the absence of more definitive studies...
  7. pmc A case of enteroviral meningoencephalitis presenting as rapidly progressive dementia
    Victor Valcour
    Department of Neurology, Memory and Aging Center, University of California, San Francisco, CA94143, USA
    Nat Clin Pract Neurol 4:399-403. 2008
    ..He had hypophonic speech and had mildly increased axial tone. He scored 5 out of 30 on the Mini Mental State Examination and was admitted for expedited evaluation...
  8. pmc The Effects of Age and HIV on Neuropsychological Performance
    Victor Valcour
    Memory and Aging Center, Department of Neurology and Division of Geriatric Medicine Department of Medicine, University of California at San Francisco, San Francisco, California 94143, USA
    J Int Neuropsychol Soc 17:190-5. 2011
    ..We conclude that older age does not significantly influence neuropsychological performance among HIV patients when seronegative controls are largely composed of individuals from a similar socioeconomic background...
  9. pmc Effects of hepatitis C and HIV on cognition in women: data from the Women's Interagency HIV Study
    Howard Crystal
    Department of Neurology, SUNY Downstate Medical Center, Brooklyn, NY 11203, USA
    J Acquir Immune Defic Syndr 59:149-54. 2012
    ..To compare neuropsychological scores in women infected with HIV, women infected with both HIV and hepatitis C, and uninfected subjects...
  10. pmc Peripheral blood HIV DNA is associated with atrophy of cerebellar and subcortical gray matter
    Kalpana J Kallianpur
    Department of Medicine, Hawaii Center for AIDS, University of Hawaii, Honolulu, HI, USA
    Neurology 80:1792-9. 2013
    ..We evaluated regional brain volumes and cerebral metabolite levels as correlates of HIV DNA in peripheral blood mononuclear cells (PBMCs)...
  11. pmc Associations of cardiovascular variables and HAART with cognition in middle-aged HIV-infected and uninfected women
    Howard A Crystal
    Department of Neurology, SUNY Downstate Medical Center, Brooklyn, NY 11203, USA
    J Neurovirol 17:469-76. 2011
    ..In this cross-sectional study, we could detect neither positive nor negative effects of HAART on cognition...
  12. pmc Impact of HIV and aging on neuropsychological function
    Lauren A Wendelken
    Department of Neurology, UCSF, San Francisco, CA 94143 1207, USA
    J Neurovirol 18:256-63. 2012
    ..This review summarizes knowledge of cognition in HIV as it relates to age and presents some emerging controversies...
  13. pmc Deficits in self-awareness impact the diagnosis of asymptomatic neurocognitive impairment in HIV
    Stephanie Chiao
    School of Medicine, University of California San Francisco, San Francisco, CA 94143 1207, USA
    AIDS Res Hum Retroviruses 29:949-56. 2013
    ..These findings have important implications for use of self-report of function in the diagnosis of HIV-associated neurocognitive disorders (HAND), likely underestimating symptomatic impairment...
  14. pmc A C17T polymorphism in the mu opiate receptor is associated with quantitative measures of drug use in African American women
    Howard A Crystal
    Department of Neurology, SUNY Downstate Medical Center, Brooklyn, NY 11203, USA
    Addict Biol 17:181-91. 2012
    ..1 (P = 0.02), 2.4 (P = 0.0004), 2.0 (P = 0.03) and 1.9 (P = 0.07). We conclude that the TT genotype of OPRM1 may increase the risk of substance use and abuse...
  15. pmc Anthropometric measures and cognition in middle-aged HIV-infected and uninfected women. The Women's Interagency HIV Study
    Deborah R Gustafson
    Department of Neurology, State University of New York Downstate Medical Center, Box 1213 450 Clarkson Ave, Brooklyn, NY, 11203, USA
    J Neurovirol 19:574-85. 2013
    ..In this era of antiretroviral therapies, restoration of health evidenced as higher BMI due to effective antiretroviral therapies, may improve cognitive function in middle-aged HIV-infected women...
  16. ncbi request reprint Small-vessel vascular disease in human immunodeficiency virus infection: the Hawaii aging with HIV cohort study
    Aaron McMurtray
    Department of Medicine, John A Burns School of Medicine, University of Hawaii, Honolulu, Hawaii 96816, USA
    Cerebrovasc Dis 24:236-41. 2007
    ..This study is designed to determine the relationship between age and occurrence of cerebral manifestations of small-vessel ischemic vascular disease in human immunodeficiency virus (HIV)-seropositive individuals...
  17. pmc Regional cortical thinning associated with detectable levels of HIV DNA
    Kalpana J Kallianpur
    Hawaii Center for AIDS, Department of Medicine, University of Hawaii, Honolulu, 96816, USA
    Cereb Cortex 22:2065-75. 2012
    ..The areas of reduced cortical thickness are key nodes in cognitive and emotional processing networks and may be etiologically important in HIV-related neurological deficits...
  18. pmc Polypharmacy, drug-drug interactions, and potentially inappropriate medications in older adults with human immunodeficiency virus infection
    Meredith Greene
    Division of Geriatrics, Department of Medicine, University of California, San Francisco, San Francisco, California San Francisco Veterans Affairs Medical Center, San Francisco, California
    J Am Geriatr Soc 62:447-53. 2014
    ..To describe the frequency of medication-related problems in older adults with human immunodeficiency virus (HIV) infection...
  19. pmc Management of human immunodeficiency virus infection in advanced age
    Meredith Greene
    Division of Geriatric Medicine, Department of Medicine, University of California, San Francisco, CA, USA
    JAMA 309:1397-405. 2013
    ..Human immunodeficiency virus (HIV)-positive patients treated with antiretroviral therapy now have increased life expectancy and develop chronic illnesses that are often seen in older HIV-negative patients...
  20. pmc Incident neuropathy in HIV-infected patients on HAART
    Beau K Nakamoto
    Hawaii Center for AIDS, Department of Medicine, John A Burns School of Medicine, University of Hawaii, Honolulu, Hawaii, USA
    AIDS Res Hum Retroviruses 26:759-65. 2010
    ..However, current or prior history of d-drug treatment is not a significant risk factor for incident DSP in subjects who had previously tolerated d-drug treatment without developing a toxic DSP...
  21. ncbi request reprint Neuropsychological test profile differences between young and old human immunodeficiency virus-positive individuals
    Ned Sacktor
    Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, Maryland, USA
    J Neurovirol 13:203-9. 2007
    ..These differences could be a result of advanced age itself or age-associated comorbidities such as coexisting cerebrovascular or neurodegenerative disease...

Research Grants3

  1. Peripheral Reservoir of HIV DNA in Monocytes Pivotal to Cognition in HIV
    Victor Valcour; Fiscal Year: 2009
    ..Understanding why this happens will allow us to find better ways to prevent or treat this devastating complication of HIV. ..
  2. Peripheral Reservoir of HIV DNA in Monocytes Pivotal to Cognition in HIV
    Victor Valcour; Fiscal Year: 2010
    ..Understanding why this happens will allow us to find better ways to prevent or treat this devastating complication of HIV. ..
  3. Neurodevelopment and Imaging among HIV-infected Children from the PREDICT study
    Victor Valcour; Fiscal Year: 2010
    ..Our findings may have an enormous impact on worldwide treatment recommendations. ..