Research Topics
| Ruben E ValasSummaryAffiliation: University of California Country: USA Publications
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Detail Information
Publications
History of biological metal utilization inferred through phylogenomic analysis of protein structuresChristopher L Dupont
Microbial and Environmental Genomics Group, J Craig Venter Institute, La Jolla, CA 92121, USA
Proc Natl Acad Sci U S A 107:10567-72. 2010..The results presented here provide an evolutionary timeline based on genomic characteristics, and key hypotheses can be tested by alternative geochemical methods...
Rethinking proteasome evolution: two novel bacterial proteasomesRuben E Valas
Bioinformatics Program, University of California, San Diego, La Jolla, CA 92093, USA
J Mol Evol 66:494-504. 2008..We have found different combinations of Anbu, BPH, and HslV within these bacterial genomes, which raises questions about specialized protein degradation systems...
Structural analysis of polarizing indels: an emerging consensus on the root of the tree of lifeRuben E Valas
Bioinformatics Program, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA
Biol Direct 4:30. 2009..However the two most comprehensive attempts at this strategy, performed by Cavalier-Smith and Lake et al., have excluded each other's rootings...
Save the tree of life or get lost in the woodsRuben E Valas
Bioinformatics Program, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA
Biol Direct 5:44. 2010..We argue that trees may still be a useful representation for evolutionary histories in light of new data...
The origin of a derived superkingdom: how a gram-positive bacterium crossed the desert to become an archaeonRuben E Valas
Bioinformatics Program, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093, USA
Biol Direct 6:16. 2011..The data have been dismissed because those who support the canonical rooting between the prokaryotic superkingdoms cannot imagine how the vast divide between the prokaryotic superkingdoms could be crossed...
Nothing about protein structure classification makes sense except in the light of evolutionRuben E Valas
Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, CA 92093 0743, USA
Curr Opin Struct Biol 19:329-34. 2009..The desired classification scheme is then one in which a fold is merely semantics and structure can be classified as either ancestral or derived...
Transcriptomic analysis of metabolic function in the giant kelp, Macrocystis pyrifera, across depth and seasonTalina Konotchick
J Craig Venter Institute, 10355 Science Center Drive, San Diego, CA, USA
New Phytol 198:398-407. 2013..g. nitrite reductase) were upregulated at depth compared with the surface, supporting a conceptual biological model of depth-dependent physiology...
