DAVID VAILLANCOURT

Summary

Affiliation: University of Illinois at Chicago
Country: USA

Publications

  1. pmc Effects of aging on the ventral and dorsal substantia nigra using diffusion tensor imaging
    David E Vaillancourt
    Departments of Kinesiology and Nutrition, University of Illinois at Chicago, Chicago, IL 60612, United States
    Neurobiol Aging 33:35-42. 2012
  2. ncbi request reprint Regularity of force tremor in Parkinson's disease
    D E Vaillancourt
    Department of Kinesiology, The Pennsylvania State University, 146 Rec Hall, University Park, PA 16802, USA
    Clin Neurophysiol 112:1594-603. 2001
  3. pmc Effects of deep brain stimulation and medication on strength, bradykinesia, and electromyographic patterns of the ankle joint in Parkinson's disease
    David E Vaillancourt
    Department of Movement Science, University of Illinois, Chicago, Illinois 60612, USA
    Mov Disord 21:50-8. 2006
  4. pmc Visual angle is the critical variable mediating gain-related effects in manual control
    David E Vaillancourt
    Department of Movement Sciences M C 994, University of Illinois at Chicago, 808 S Wood St, 690 CME, Chicago, IL 60612, USA
    Exp Brain Res 173:742-50. 2006
  5. ncbi request reprint Subthalamic nucleus and internal globus pallidus scale with the rate of change of force production in humans
    David E Vaillancourt
    Department of Movement Sciences, University of Illinois at Chicago, Chicago, IL 60612, USA
    Neuroimage 23:175-86. 2004
  6. pmc Role of the basal ganglia and frontal cortex in selecting and producing internally guided force pulses
    David E Vaillancourt
    Department of Movement Sciences, University of Illinois at Chicago, Chicago, IL 60612, USA
    Neuroimage 36:793-803. 2007
  7. ncbi request reprint Effects of deep brain stimulation and medication on bradykinesia and muscle activation in Parkinson's disease
    David E Vaillancourt
    Department of Movement Science, University of Illinois at Chicago, 901 West Roosevelt Road, Chicago, IL 60608, USA
    Brain 127:491-504. 2004
  8. ncbi request reprint Deep brain stimulation of the VIM thalamic nucleus modifies several features of essential tremor
    D E Vaillancourt
    School of Kinesiology, University of Illinois at Chicago, IL 60608, USA
    Neurology 61:919-25. 2003
  9. pmc High-resolution diffusion tensor imaging in the substantia nigra of de novo Parkinson disease
    D E Vaillancourt
    Department of Kinesiology and Nutrition, University of Illinois at Chicago, 1919 West Taylor, 650 AHSB, MC 994, Chicago, IL 60612, USA
    Neurology 72:1378-84. 2009
  10. ncbi request reprint Neural basis for the processes that underlie visually guided and internally guided force control in humans
    David E Vaillancourt
    School of Kinesiology, Department of Neurology, University of Illinois at Chicago, Chicago, Illinois 60608, USA
    J Neurophysiol 90:3330-40. 2003

Research Grants

Detail Information

Publications43

  1. pmc Effects of aging on the ventral and dorsal substantia nigra using diffusion tensor imaging
    David E Vaillancourt
    Departments of Kinesiology and Nutrition, University of Illinois at Chicago, Chicago, IL 60612, United States
    Neurobiol Aging 33:35-42. 2012
    ....
  2. ncbi request reprint Regularity of force tremor in Parkinson's disease
    D E Vaillancourt
    Department of Kinesiology, The Pennsylvania State University, 146 Rec Hall, University Park, PA 16802, USA
    Clin Neurophysiol 112:1594-603. 2001
    ....
  3. pmc Effects of deep brain stimulation and medication on strength, bradykinesia, and electromyographic patterns of the ankle joint in Parkinson's disease
    David E Vaillancourt
    Department of Movement Science, University of Illinois, Chicago, Illinois 60612, USA
    Mov Disord 21:50-8. 2006
    ..The findings are the first to demonstrate that STN DBS and medication increase strength and movement velocity at the ankle joint...
  4. pmc Visual angle is the critical variable mediating gain-related effects in manual control
    David E Vaillancourt
    Department of Movement Sciences M C 994, University of Illinois at Chicago, 808 S Wood St, 690 CME, Chicago, IL 60612, USA
    Exp Brain Res 173:742-50. 2006
    ..Visual angle is the critical informational variable for the visuomotor system during the control of isometric force...
  5. ncbi request reprint Subthalamic nucleus and internal globus pallidus scale with the rate of change of force production in humans
    David E Vaillancourt
    Department of Movement Sciences, University of Illinois at Chicago, Chicago, IL 60612, USA
    Neuroimage 23:175-86. 2004
    ..In contrast, movements that require the internal regulation of the rate of change of force are associated with increased metabolic demand from the subthalamic nucleus and internal segment of the globus pallidus...
  6. pmc Role of the basal ganglia and frontal cortex in selecting and producing internally guided force pulses
    David E Vaillancourt
    Department of Movement Sciences, University of Illinois at Chicago, Chicago, IL 60612, USA
    Neuroimage 36:793-803. 2007
    ..These findings suggest that anterior basal ganglia nuclei are involved in selecting the amplitude of force contractions and posterior basal ganglia nuclei regulate basic aspects of dynamic force pulse production...
  7. ncbi request reprint Effects of deep brain stimulation and medication on bradykinesia and muscle activation in Parkinson's disease
    David E Vaillancourt
    Department of Movement Science, University of Illinois at Chicago, 901 West Roosevelt Road, Chicago, IL 60608, USA
    Brain 127:491-504. 2004
    ..These findings suggest a link between basal ganglia function in scaling both the amplitude and temporal parameters of the input to the motor neuron pool...
  8. ncbi request reprint Deep brain stimulation of the VIM thalamic nucleus modifies several features of essential tremor
    D E Vaillancourt
    School of Kinesiology, University of Illinois at Chicago, IL 60608, USA
    Neurology 61:919-25. 2003
    ..Deep brain stimulation (DBS) of the ventral intermediate (VIM) nucleus of the thalamus successfully reduces tremor rating scores. It is unknown how VIM DBS alters the pathophysiologic characteristics of ET...
  9. pmc High-resolution diffusion tensor imaging in the substantia nigra of de novo Parkinson disease
    D E Vaillancourt
    Department of Kinesiology and Nutrition, University of Illinois at Chicago, 1919 West Taylor, 650 AHSB, MC 994, Chicago, IL 60612, USA
    Neurology 72:1378-84. 2009
    ....
  10. ncbi request reprint Neural basis for the processes that underlie visually guided and internally guided force control in humans
    David E Vaillancourt
    School of Kinesiology, Department of Neurology, University of Illinois at Chicago, Chicago, Illinois 60608, USA
    J Neurophysiol 90:3330-40. 2003
    ..In contrast, a localized network in the prefrontal cortex retrieves force output from memory during internally guided actions...
  11. ncbi request reprint Aging and the time and frequency structure of force output variability
    David E Vaillancourt
    School of Kinesiology, University of Illinois at Chicago, Chicago, Illinois 60608, USA
    J Appl Physiol 94:903-12. 2003
    ..Neurobiol Aging 23: 1-11, 2002)...
  12. ncbi request reprint Visual control of isometric force in Parkinson's disease
    D E Vaillancourt
    Department of Kinesiology, The Pennsylvania State University, 266 Recreation Building, University Park, PA 16802, USA
    Neuropsychologia 39:1410-8. 2001
    ..It is proposed that the increased force decay in PD does not result from sensory reflex deficits but from higher order sensory-motor memory processes...
  13. ncbi request reprint Changing complexity in human behavior and physiology through aging and disease
    David E Vaillancourt
    Department of Kinesiology, The Pennsylvania State University, University Park, PA 16802, USA
    Neurobiol Aging 23:1-11. 2002
    ..It is postulated that the observed increase or decrease in complexity with aging and disease is dependent on the nature of both the intrinsic dynamics of the system and the short-term change required to realize a local task demand...
  14. ncbi request reprint Complexity in aging and disease: response to commentaries
    David E Vaillancourt
    School of Kinesiology, The University of Illinois at Chicago, 60608, USA
    Neurobiol Aging 23:27-9. 2002
  15. pmc Intermittent visuomotor processing in the human cerebellum, parietal cortex, and premotor cortex
    David E Vaillancourt
    Department of Movement Sciences, University of Illinois at Chicago, Chicago, Illinois 60612, USA
    J Neurophysiol 95:922-31. 2006
    ..These findings demonstrate that the frequency of visual information reduces motor error and differentially modulates the neural activation related to visuomotor processing in the cerebellum, parietal cortex, and premotor cortex...
  16. ncbi request reprint Temporal capacity of short-term visuomotor memory in continuous force production
    David E Vaillancourt
    School of Kinesiology M C 194, University of Illinois at Chicago, 901 West Roosevelt, Chicago, IL 60608, USA
    Exp Brain Res 145:275-85. 2002
    ..It is concluded that the 0.5- to 1.5-s time period represents a limit on the temporal capacity that precise visuomotor information is held in short-term memory...
  17. ncbi request reprint Time-dependent structure in the discharge rate of human motor units
    David E Vaillancourt
    School of Kinesiology, The University of Illinois at Chicago, 901 West Roosevelt, Chicago, IL 60608, USA
    Clin Neurophysiol 113:1325-38. 2002
    ..The aim of this study was to examine the influence of visual and motor processes on the deterministic and stochastic structure of force output and motor unit discharge variability...
  18. ncbi request reprint Effects of aging on force variability, single motor unit discharge patterns, and the structure of 10, 20, and 40 Hz EMG activity
    David E Vaillancourt
    School of Kinesiology M C 194, The University of Illinois at Chicago, 901 West Roosevelt Road, Chicago, IL 60608, USA
    Neurobiol Aging 24:25-35. 2003
    ..The findings showed that a shift in the relative contribution of approximately 40 Hz to approximately 10 Hz neural activity is related to the reduced capacity of older adults to maintain optimal force control...
  19. pmc Role of hyperactive cerebellum and motor cortex in Parkinson's disease
    Hong Yu
    Department of Movement Sciences, University of Illinois at Chicago, Chicago, IL 60612, USA
    Neuroimage 35:222-33. 2007
    ..Our findings also provide the first evidence from neuroimaging that hyperactivation in the contralateral primary motor cortex is not a compensatory response but is directly related to upper limb rigidity...
  20. pmc Blood oxygenation level-dependent activation in basal ganglia nuclei relates to specific symptoms in de novo Parkinson's disease
    Janey Prodoehl
    Department of Kinesiology and Nutrition, University of Illinois at Chicago, Chicago, Illinois, USA
    Mov Disord 25:2035-43. 2010
    ....
  21. doi request reprint Effects of visual and auditory feedback on sensorimotor circuits in the basal ganglia
    Janey Prodoehl
    Department of Kinesiology and Nutrition, University of Illinois at Chicago, 1919 West Taylor Street, 650 AHSB, M C 994, Chicago, IL 60612, USA
    J Neurophysiol 99:3042-51. 2008
    ..Also, the data are consistent with the hypothesis that the GPe has a high level of information convergence from other BG nuclei, which is preserved across different sensory feedback modalities...
  22. pmc Role of individual basal ganglia nuclei in force amplitude generation
    Matthew B Spraker
    Department of Bioengineering, University of Illinois at Chicago, Chicago, IL 60612, USA
    J Neurophysiol 98:821-34. 2007
    ..Our findings provide direct evidence that GPi and STN regulate the amplitude of force output. These findings emphasize the heterogeneous role of individual nuclei of the basal ganglia in regulating specific parameters of motor output...
  23. ncbi request reprint Aging and rhythmical force output: loss of adaptive control of multiple neural oscillators
    Jacob J Sosnoff
    Department of Kinesiology, The Pennsylvania State University, University Park, Pennsylvania 16802, USA
    J Neurophysiol 91:172-81. 2004
    ..Furthermore, it is proposed that aging humans lose the adaptive capability to coordinate the excitatory and inhibitory activity of multiple neural oscillators...
  24. pmc Predicting grip force amplitude involves circuits in the anterior basal ganglia
    Pooja Wasson
    Department of Kinesiology and Nutrition, University of Illinois at Chicago, Chicago, IL, USA
    Neuroimage 49:3230-8. 2010
    ..Further, the results provide additional support for the planning and parameterization model of the basal ganglia by demonstrating that specific anterior nuclei of the basal ganglia are involved in planning grip force...
  25. pmc Region of interest template for the human basal ganglia: comparing EPI and standardized space approaches
    Janey Prodoehl
    Department of Kinesiology and Nutrition, University of Illinois at Chicago, Chicago, IL 60612, USA
    Neuroimage 39:956-65. 2008
    ..Use of a mask drawn in standardized space is a valid and time saving method of identifying PSC in the small nuclei of the BG...
  26. pmc Cortical and subcortical mechanisms for precisely controlled force generation and force relaxation
    Matthew B Spraker
    Department of Bioengineering, University of Illinois at Chicago, Chicago, IL 60612, USA
    Cereb Cortex 19:2640-50. 2009
    ..Moreover, this study demonstrates that the DLPFC is not only involved in slow and precisely controlled force generation, but has greater involvement in regulating slow and precisely controlled muscle relaxation...
  27. pmc Spatiotemporal tuning of brain activity and force performance
    Stephen A Coombes
    Department of Kinesiology and Nutrition, University of Illinois at Chicago, Chicago, IL 60612, USA
    Neuroimage 54:2226-36. 2011
    ..This study demonstrates that the frequency of visual feedback drives where in the brain visual gain mediated reductions in force error are regulated...
  28. pmc Basal ganglia mechanisms underlying precision grip force control
    Janey Prodoehl
    Department of Kinesiology and Nutrition, University of Illinois at Chicago, Chicago, IL 60612, USA
    Neurosci Biobehav Rev 33:900-8. 2009
    ....
  29. pmc Effects of visual gain on force control at the elbow and ankle
    Janey Prodoehl
    Department of Kinesiology and Nutrition, University of Illinois at Chicago, 1919 West Taylor Street, 650 AHSB, M C 994, Chicago, IL 60612, USA
    Exp Brain Res 200:67-79. 2010
    ..The results suggest better use of visual information in the control of elbow force than ankle force and this improved control may be related to the changes in the pattern of agonist and antagonist activation...
  30. doi request reprint Effects of five years of chronic STN stimulation on muscle strength and movement speed
    Molly M Sturman
    Department of Kinesiology and Nutrition, University of Illinois at Chicago, 1919 West Taylor Street, 650 AHSB, M C 994, Chicago, IL 60612, USA
    Exp Brain Res 205:435-43. 2010
    ..The current findings suggest that 5 years of chronic STN DBS can have beneficial effects on the motor system over the long term in discrete motor tasks in which maximal effort and maximal neural output is required...
  31. pmc Selective regions of the visuomotor system are related to gain-induced changes in force error
    Stephen A Coombes
    Department of Kinesiology and Nutrition, University of Illinois at Chicago, 1919 West Taylor, 650 AHSB, M C 994, Chicago, IL 60612, USA
    J Neurophysiol 103:2114-23. 2010
    ..Instead, specific regions of the visuomotor system selectively change in activity related to large changes in force error and large changes in the spatial amplitude of visual feedback...
  32. pmc Variability of EMG patterns: a potential neurophysiological marker of Parkinson's disease?
    Julie A Robichaud
    Department of Kinesiology and Nutrition M C 994, University of Illinois at Chicago, 1919 West Taylor Street, 650 AHSB, MC 994, Chicago, IL 60612, USA
    Clin Neurophysiol 120:390-7. 2009
    ....
  33. doi request reprint Effect of short and long term STN stimulation periods on parkinsonian signs
    Molly M Sturman
    Department of Kinesiology and Nutrition, University of Illinois at Chicago, Chicago, Illinois, USA
    Mov Disord 23:866-74. 2008
    ..As such, it is reasonable to evaluate the effect of DBS after 90 min of stimulation in clinical trials and research studies...
  34. ncbi request reprint Effects of subthalamic nucleus stimulation and medication on resting and postural tremor in Parkinson's disease
    Molly M Sturman
    Department of Movement Sciences M C 994, College of Applied Health Sciences, University of Illinois at Chicago, 808 S Wood Street, 690 CME, Chicago, IL 60612, USA
    Brain 127:2131-43. 2004
    ..The findings suggest that neural activity in the STN is an important modulator of the neural network(s) responsible for both resting and postural tremor genesis in Parkinson's disease...
  35. ncbi request reprint Coherence of EMG activity and single motor unit discharge patterns in human rhythmical force production
    Jacob J Sosnoff
    Department of Kinesiology, The Pennsylvania State University, 266 Recreation Hall, University Park, PA 16802, USA
    Behav Brain Res 158:301-10. 2005
    ..The modulation of the motor neuronal pool is adaptive and depends on the relative contribution of feedback and feedforward control processes, which are driven by the task demands...
  36. ncbi request reprint Effects of aging on the regularity of physiological tremor
    Molly M Sturman
    Department of Movement Sciences M C 994 University of Illinois at Chicago, 808 South Wood, 690 CMET, Chicago, IL 60612, USA
    J Neurophysiol 93:3064-74. 2005
    ....
  37. pmc Three-dimensional locations and boundaries of motor and premotor cortices as defined by functional brain imaging: a meta-analysis
    Mary A Mayka
    Department of Movement Sciences, University of Illinois at Chicago, Chicago, IL 60612, USA
    Neuroimage 31:1453-74. 2006
    ..HMAT is available through e-mail from the corresponding author...
  38. pmc Deep brain stimulation and medication for parkinsonian tremor during secondary tasks
    Molly M Sturman
    Department of Movement Sciences, University of Illinois at Chicago, Chicago, IL 60612, USA
    Mov Disord 22:1157-63. 2007
    ..These findings demonstrate that STN DBS still suppresses tremor in the presence of a cognitive task. Furthermore, a secondary motor task of the opposite limb suppresses tremor to levels comparable to STN DBS...
  39. pmc Effects of STN DBS on memory guided force control in Parkinson's disease (June 2007)
    Janey Prodoehl
    Department of Movement Sciences, University of Illinois, Chicago, IL 60608, USA
    IEEE Trans Neural Syst Rehabil Eng 15:155-65. 2007
    ..We suggest that modulation of output of the internal segment of the globus pallidus by STN DBS may drive the effect of STN DBS on memory guided force control...
  40. pmc Effects of STN DBS on rigidity in Parkinson's disease
    Mark B Shapiro
    University of Illinois, Chicago, IL 60612, USA
    IEEE Trans Neural Syst Rehabil Eng 15:173-81. 2007
    ..Our results suggest that STN DBS may be more effective in alleviating rigidity in the upper limb of PD patients than medications administered at presurgery dosage level...
  41. ncbi request reprint Inter-digit individuation and force variability in the precision grip of young, elderly, and Parkinson's disease participants
    David E Vaillancourt
    School of Kinesiology, University of Illinois at Chicago, Chicago, IL 60608, USA
    Motor Control 6:113-28. 2002
    ..The force fluctuations in precision grip revealed a continuum for the degree of inter-digit individuation in which task constraints, aging, and Parkinson's disease alter the coupling between the digits in controlling grip force...
  42. ncbi request reprint Force control and disease severity in Parkinson's disease
    Julie A Robichaud
    Department of Physical Therapy, School of Health and Rehabilitation Sciences, Indiana University, Indianapolis, Indiana 46202, USA
    Mov Disord 20:441-50. 2005
    ..These measures provide objective quantification of the severity of motor impairment that can be used to investigate the efficacy of different interventions in individuals with PD...
  43. ncbi request reprint Age-related changes in complexity depend on task dynamics
    David E Vaillancourt
    J Appl Physiol 97:454-5. 2004

Research Grants10

  1. fMRI Activity During the Visual Control of Force
    DAVID VAILLANCOURT; Fiscal Year: 2004
    ..These findings will have further implications for better understanding the visuomotor control deficits associated with aging, and diseased persons with Parkinson's disease, ataxia, and cerebellar deficits. ..
  2. Role of Cortex and Cerebellum in Visually-Guided Motor Behavior
    David E Vaillancourt; Fiscal Year: 2010
    ..This is the first step toward our long-term goal of using patient-specific visual feedback displays during neurological rehabilitation to facilitate brain activation and maximize recovery of function. ..
  3. Role of Cortex and Cerebellum in Visually-Guided Motor Behavior
    DAVID VAILLANCOURT; Fiscal Year: 2009
    ..This is the first step toward our long-term goal of using patient-specific visual feedback displays during neurological rehabilitation to facilitate brain activation and maximize recovery of function. ..
  4. Scaling and Sequencing Motor Output in Humans: fMRI Study
    DAVID VAILLANCOURT; Fiscal Year: 2007
    ..As such, the proposal will have direct application to understanding the motor deficits of millions of Americans who suffer from basal ganglia dysfunction such as Parkinson's disease, stroke, dystonia, and Huntingdon's disease. ..
  5. Scaling and Sequencing Motor Output in Humans: fMRI Study
    David E Vaillancourt; Fiscal Year: 2010
    ..Since very little is known regarding the brain function of Parkinson's disease prior to taking medication, we will perform our studies before patients begin a drug treatment program for the disease. ..