Research Topics
Species | S VaidyaSummaryAffiliation: University of Texas Medical Branch Country: USA Publications
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Detail Information
Publications
Ten-yr renal allograft survival of patients with antiphospholipid antibody syndromeSmita Vaidya
Department of Pathology, University of Texas Medical Branch, Galveston, TX 77555, USA
Clin Transplant 26:853-6. 2012..This study evaluates long-term allograft survival of APA as well as patients with APAS...
Clinical importance of anti-human leukocyte antigen-specific antibody concentration in performing calculated panel reactive antibody and virtual crossmatchesSmita Vaidya
Department of Pathology, University of Texas Medical Branch, Galveston, TX 77555 0178, USA
Transplantation 85:1046-50. 2008..This was used to determine MESF units required for a positive T and B flow crossmatches (FLXM)...
DP reactive antibody in a zero mismatch renal transplant pairSmita Vaidya
Department of Pathology, University of Texas Medical Branch, Galveston, Texas, USA
Hum Immunol 68:947-9. 2007..The MM allele DPB1*0601 also carries the DE 55-56 epitope. We conclude that positive B-cell flow crossmatch was likely the result of single MM in the DP locus...
Pretransplant soluble CD30 is a better predictor of posttransplant development of donor-specific antibodies and acute vascular rejection than panel reactive antibodiesSmita Vaidya
Department of Pathology, University of Texas Medical Branch, Galveston, TX, USA
Transplantation 82:1606-9. 2006....
Prediction of crossmatch outcome of highly sensitized patients by single and/or multiple antigen bead luminex assaySmita Vaidya
Department of Pathology, University of Texas Medical Branch, Galveston, TX 77555, USA
Transplantation 82:1524-8. 2006..We used a solid-phase assay to identify human leukocyte antigen (HLA) Class I and II specificities in highly reactive sera, and applied this information to predict crossmatch outcome with greater than 90% accuracy...
Soluble CD30 concentrations in ESRD patients with and without panel reactive HLA antibodiesSmita Vaidya
Department of Pathology, University of Texas Medical Branch, Galveston, TX 77555 0178, USA
Clin Transplant 20:461-4. 2006..In this retrospective study we compared accuracy of panel reactive antibodies (PRA) with serum soluble CD30 (sCD30) contents in predicting acute rejection crisis post-renal transplant...
Management of end-stage renal disease patients with antiphospholipid antibody syndromeS Vaidya
Department of Pathology, University of Texas Medical Branch, Galveston, Texas 77555 0178, USA
Transplant Proc 37:650-1. 2005..This study describes the clinical management of these high-risk patients on anticoagulation therapy...
Synthesis of new and memory HLA antibodies from acute and chronic rejections versus pregnancies and blood transfusionsS Vaidya
Department of Pathology, University of Texas Medical Branch, Galveston, Texas 77555 0178, USA
Transplant Proc 37:648-9. 2005..This study compared HLA antibody (abs) production following acute (AR) and chronic (CR) rejection with HLA abs production following blood transfusions (TF) or pregnancies (P) among kidney and kidney pancreas transplant candidates...
Efficacy of anticoagulation therapy in end-stage renal disease patients with antiphospholipid antibody syndromeSmita Vaidya
Department of Pathology, University of Texas Medical Branch, Galveston, TX, USA
Transplantation 77:1046-9. 2004..This study examines the efficacy of anticoagulation therapy in this high-risk patient population...
Role of anti-beta 2 glycoprotein 1 antibodies in ESRD patients with antiphospholipid antibody syndromeS Vaidya
Department of Pathology, The University of Texas Medical Branch, Galveston, TX 77555 0178, USA
Clin Transplant 16:362-7. 2002..Beta 2 glycoprotein 1 (beta 2gp1), a 40-kD plasma protein is required. In this study, we have tested a hypothesis that significant portions of our ESRD patients with APAS have antibodies only to beta 2gp1...
Frequency, potential risk and therapeutic intervention in end-stage renal disease patients with antiphospholipid antibody syndrome: a multicenter studyS Vaidya
University of Texas Medical Branch, Galveston 77555 0178, USA
Transplantation 69:1348-52. 2000..Antiphospholipid antibody syndrome (APAS) is characterized by the presence of anticardiolipin antibodies (ACA) in association with thrombotic disorders of arterial and/or venus systems, spontaneous abortion(s) or thrombocytopenia...
Improved flow cytometric detection of HLA alloantibodies using pronase: potential implications in renal transplantationS Vaidya
Department of Pathology, University of Texas Medical Branch, Galveston 77555-0178, USA
Transplantation 71:422-8. 2001..fied in each case. CONCLUSION: Utilization of pronase-treated lymphocytes improves both the sensitivity and specificity of the FCXM...
Campath and renal transplant rejectionPhilip G Thomas
Department of Surgery, The University of Texas Medical Branch, Galveston, TX 77555, USA
Clin Transplant 18:759-61. 2004..However, rejection recurred resulting in graft loss and, in addition, the patient developed post-transplant lymphoma...
Alemtuzumab (Campath 1H) induction with tacrolimus monotherapy is safe for high immunological risk renal transplantationPhilip G Thomas
Department of Surgery, University of Texas Medical Branch, Galveston, TX 77555 0533, USA
Transplantation 83:1509-12. 2007..Infection rates were similar. Early results of this ongoing study indicate that a tolerogenic protocol with alemtuzumab induction and tacrolimus maintenance monotherapy is safe in immunologically high-risk renal transplant patients...
Peri-operative alemtuzumab (Campath-1H) and plasmapheresis for high-PRA positive lymphocyte crossmatch heart transplant: a strategy to shorten left ventricular assist device supportScott D Lick
Department of Surgery, University of Texas Medical Branch, Galveston, Texas 77555, USA
J Heart Lung Transplant 27:1036-9. 2008..Expanded use of this strategy could shorten LVAD support in many sensitized patients...
