Giske Ursin

Summary

Affiliation: University of Southern California
Country: USA

Publications

  1. pmc Recent breast cancer incidence trends according to hormone therapy use: the California Teachers Study cohort
    Sarah F Marshall
    Department of Epidemiology, School of Medicine, University of California, Irvine, 224 Irvine Hall, Irvine, CA 92697, USA
    Breast Cancer Res 12:R4. 2010
  2. pmc Different measures of smoking exposure and mammographic density in postmenopausal Norwegian women: a cross-sectional study
    Yngve Bremnes
    Institute of Community Medicine, University of Tromsø, Tromsø, Norway
    Breast Cancer Res 9:R73. 2007
  3. pmc Pregnancy-related factors and the risk of breast carcinoma in situ and invasive breast cancer among postmenopausal women in the California Teachers Study cohort
    Huiyan Ma
    Department of Population Sciences, Beckman Research Institute, City of Hope, 1500 East Duarte Road, Duarte, CA 91010, USA
    Breast Cancer Res 12:R35. 2010
  4. pmc Plasma levels of leptin and mammographic density among postmenopausal women: a cross-sectional study
    Anne Stuedal
    Department of Nutrition, University of Oslo, Norway
    Breast Cancer Res 8:R55. 2006
  5. ncbi request reprint Post-treatment change in serum estrone predicts mammographic percent density changes in women who received combination estrogen and progestin in the Postmenopausal Estrogen/Progestin Interventions (PEPI) Trial
    Giske Ursin
    Department of Preventive Medicine, Norris Comprehensive Cancer Center, Room 4407, USC Keck School of Medicine, 1441 Eastlake Avenue, Los Angeles, CA 90089, USA
    J Clin Oncol 22:2842-8. 2004
  6. ncbi request reprint Reproductive factors and risk of breast carcinoma in a study of white and African-American women
    Giske Ursin
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA
    Cancer 101:353-62. 2004
  7. pmc Reproductive factors and subtypes of breast cancer defined by hormone receptor and histology
    G Ursin
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA, USA
    Br J Cancer 93:364-71. 2005
  8. pmc Greatly increased occurrence of breast cancers in areas of mammographically dense tissue
    Giske Ursin
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California, USA
    Breast Cancer Res 7:R605-8. 2005
  9. ncbi request reprint Associations between soy, diet, reproductive factors, and mammographic density in Singapore Chinese women
    Giske Ursin
    University of Southern California, Los Angeles, CA 90089, USA
    Nutr Cancer 56:128-35. 2006
  10. doi request reprint Effect of reproductive factors and oral contraceptives on breast cancer risk in BRCA1/2 mutation carriers and noncarriers: results from a population-based study
    Eunjung Lee
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Room 4407, 1441 Eastlake Avenue, Los Angeles, CA 90089, USA
    Cancer Epidemiol Biomarkers Prev 17:3170-8. 2008

Detail Information

Publications89

  1. pmc Recent breast cancer incidence trends according to hormone therapy use: the California Teachers Study cohort
    Sarah F Marshall
    Department of Epidemiology, School of Medicine, University of California, Irvine, 224 Irvine Hall, Irvine, CA 92697, USA
    Breast Cancer Res 12:R4. 2010
    ..Few data sources can address breast cancer incidence trends according to pertinent characteristics like hormone therapy use history...
  2. pmc Different measures of smoking exposure and mammographic density in postmenopausal Norwegian women: a cross-sectional study
    Yngve Bremnes
    Institute of Community Medicine, University of Tromsø, Tromsø, Norway
    Breast Cancer Res 9:R73. 2007
    ..Cigarette smoking may have both carcinogenic effects and antiestrogenic effects on the breast tissue. We decided to examine the relationship between different measures of smoking exposure and mammographic density...
  3. pmc Pregnancy-related factors and the risk of breast carcinoma in situ and invasive breast cancer among postmenopausal women in the California Teachers Study cohort
    Huiyan Ma
    Department of Population Sciences, Beckman Research Institute, City of Hope, 1500 East Duarte Road, Duarte, CA 91010, USA
    Breast Cancer Res 12:R35. 2010
    ....
  4. pmc Plasma levels of leptin and mammographic density among postmenopausal women: a cross-sectional study
    Anne Stuedal
    Department of Nutrition, University of Oslo, Norway
    Breast Cancer Res 8:R55. 2006
    ..Leptin is a protein produced mainly by adipose tissue and may represent a growth factor in cancer. We examined the association between leptin plasma levels and mammographic density, a biomarker for breast cancer risk...
  5. ncbi request reprint Post-treatment change in serum estrone predicts mammographic percent density changes in women who received combination estrogen and progestin in the Postmenopausal Estrogen/Progestin Interventions (PEPI) Trial
    Giske Ursin
    Department of Preventive Medicine, Norris Comprehensive Cancer Center, Room 4407, USC Keck School of Medicine, 1441 Eastlake Avenue, Los Angeles, CA 90089, USA
    J Clin Oncol 22:2842-8. 2004
    ..We determined whether increases in serum estrone as a function of treatment predict increases in mammographic percent density...
  6. ncbi request reprint Reproductive factors and risk of breast carcinoma in a study of white and African-American women
    Giske Ursin
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA
    Cancer 101:353-62. 2004
    ....
  7. pmc Reproductive factors and subtypes of breast cancer defined by hormone receptor and histology
    G Ursin
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA, USA
    Br J Cancer 93:364-71. 2005
    ..This suggests that parity and lactation act through different mechanisms. This study also suggests that reproductive factors have similar protective effects on breast tumours of lobular and ductal origin...
  8. pmc Greatly increased occurrence of breast cancers in areas of mammographically dense tissue
    Giske Ursin
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, California, USA
    Breast Cancer Res 7:R605-8. 2005
    ..We addressed this question by studying ductal carcinoma in situ (DCIS), as revealed by microcalcifications...
  9. ncbi request reprint Associations between soy, diet, reproductive factors, and mammographic density in Singapore Chinese women
    Giske Ursin
    University of Southern California, Los Angeles, CA 90089, USA
    Nutr Cancer 56:128-35. 2006
    ..Our results suggest that the effect of soy intake on percent mammographic density is moderate but possibly of clinical relevance...
  10. doi request reprint Effect of reproductive factors and oral contraceptives on breast cancer risk in BRCA1/2 mutation carriers and noncarriers: results from a population-based study
    Eunjung Lee
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, Room 4407, 1441 Eastlake Avenue, Los Angeles, CA 90089, USA
    Cancer Epidemiol Biomarkers Prev 17:3170-8. 2008
    ..However, the effects of these factors in BRCA1 and BRCA2 mutation carriers are less clear...
  11. pmc Variations in sex hormone metabolism genes, postmenopausal hormone therapy and risk of endometrial cancer
    Pedram Razavi
    Department of Preventive Medicine, University of Southern California, Los Angeles, CA, USA
    Int J Cancer 130:1629-38. 2012
    ..Variations in CYP11A1 may modify the effect of ET use on risk of postmenopausal endometrial cancer; however, larger studies are needed to explore these findings further...
  12. doi request reprint Progestogen levels, progesterone receptor gene polymorphisms, and mammographic density changes: results from the Postmenopausal Estrogen/Progestin Interventions Mammographic Density Study
    Eunjung Lee
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
    Menopause 19:302-10. 2012
    ..Here, after adjusting for serum estrone and estrone sulfate levels, we investigated the roles of posttreatment serum progestogen increase and of progesterone receptor gene (PGR) genetic variations on changes in mammographic density...
  13. pmc Genetic variation in the progesterone receptor gene and risk of endometrial cancer: a haplotype-based approach
    Eunjung Lee
    Department of Preventive Medicine, University of Southern California, Los Angeles, CA 90089, USA
    Carcinogenesis 31:1392-9. 2010
    ..We investigated whether genetic variation in PGR is also associated with endometrial cancer risk using a haplotype-based approach...
  14. ncbi request reprint Mammographic density and breast cancer in three ethnic groups
    Giske Ursin
    Department of Preventive Medicine, University of California Keck School of Medicine, Los Angeles, California 90089, USA
    Cancer Epidemiol Biomarkers Prev 12:332-8. 2003
    ..Furthermore, our findings suggest that mammographic density is as strong a predictor of risk for African-American and Asian-American women as for white women...
  15. pmc Genetic variation in peroxisome proliferator-activated receptor gamma, soy, and mammographic density in Singapore Chinese women
    Eunjung Lee
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, 1441 Eastlake Ave, Norris Cancer Center, Los Angeles, CA 90089, USA
    Cancer Epidemiol Biomarkers Prev 21:635-44. 2012
    ..We investigated the interrelations of soy, PPARγ, and mammographic density, a biomarker of breast cancer risk in a cross-sectional study of 2,038 women who were members of the population-based Singapore Chinese Health Study Cohort...
  16. doi request reprint Hormone metabolism genes and mammographic density in Singapore Chinese women
    Eunjung Lee
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
    Cancer Epidemiol Biomarkers Prev 22:984-6. 2013
    ..We investigated the association between genetic variation in the hormone metabolism and signaling pathway and mammographic density, a strong predictor of breast cancer risk...
  17. pmc Age-specific effects of hormone therapy use on overall mortality and ischemic heart disease mortality among women in the California Teachers Study
    Daniel O Stram
    Department of Preventive Medicine, University of Southern California, Los Angeles, CA 90033, USA
    Menopause 18:253-61. 2011
    ..The California Teachers Study questionnaire and mortality data were used to examine whether age modified the association between HT and the relative risk of overall mortality and ischemic heart disease deaths...
  18. pmc The association of polymorphisms in hormone metabolism pathway genes, menopausal hormone therapy, and breast cancer risk: a nested case-control study in the California Teachers Study cohort
    Eunjung Lee
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, 1441 Eastlake Avenue, Los Angeles, CA 90089, USA
    Breast Cancer Res 13:R37. 2011
    ..It therefore seems plausible that variation in genes involved in metabolism of these hormones may affect breast cancer risk, and that these associations may vary depending on menopausal status and use of hormone therapy...
  19. pmc Mitochondrial DNA G10398A variant is not associated with breast cancer in African-American women
    Veronica Wendy Setiawan
    Department of Preventive Medicine, Keck School of Medicine and Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA, USA
    Cancer Genet Cytogenet 181:16-9. 2008
    ..18, 95% CI = 0.76-1.82, P = 0.46). Our results do not support the hypothesis that the mtDNA G10398A polymorphism is, as has previously been reported, a marker of breast cancer risk in African Americans...
  20. pmc Polymorphisms in genes involved in estrogen and progesterone metabolism and mammographic density changes in women randomized to postmenopausal hormone therapy: results from a pilot study
    Sarah J Lord
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
    Breast Cancer Res 7:R336-44. 2005
    ..Identifying genetic variants that determine increases in mammographic density in hormone users may be important in understanding hormonal carcinogenesis of the breast...
  21. ncbi request reprint Does mammographic density reflect ethnic differences in breast cancer incidence rates?
    Zhengjia Chen
    Department of Preventive Medicine, University of Southern California Keck School of Medicine, Los Angeles, CA, USA
    Am J Epidemiol 159:140-7. 2004
    ..This study suggests that absolute but not percent mammographic density reflects the lower breast cancer incidence rates of Asian Americans in relation to those of African Americans and Whites...
  22. doi request reprint The relative importance of genetics and environment on mammographic density
    Giske Ursin
    Department of Preventive Medicine, University of Southern California Keck School of Medicine, Norris Comprehensive Cancer Center, Los Angeles, California, USA
    Cancer Epidemiol Biomarkers Prev 18:102-12. 2009
    ..We investigated whether part of the presumed heritability might be attributed to differential sharing of modifiable risk factors in monozygotic (MZ) and dizygotic (DZ) twins...
  23. ncbi request reprint Postmenopausal hormone therapy and change in mammographic density
    Gail A Greendale
    Division of Geriatric Medicine, David Geffen School of Medicine at UCLA, Los Angeles, CA 90095, USA
    J Natl Cancer Inst 95:30-7. 2003
    ..Mammographic density is an independent risk factor for breast cancer. Postmenopausal hormone use is associated with an increase in mammographic density, but the magnitude of the density increase is unknown...
  24. doi request reprint Is there a difference in the association between percent mammographic density and subtypes of breast cancer? Luminal A and triple-negative breast cancer
    Huiyan Ma
    Division of Cancer Etiology, Department of Population Sciences, City of Hope National Medical Center, Duarte, CA, USA
    Cancer Epidemiol Biomarkers Prev 18:479-85. 2009
    ....
  25. pmc Two estrogen-related variants in CYP19A1 and endometrial cancer risk: a pooled analysis in the Epidemiology of Endometrial Cancer Consortium
    Veronica Wendy Setiawan
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
    Cancer Epidemiol Biomarkers Prev 18:242-7. 2009
    ..Our study provides evidence that CYP19A1 genetic variation influences susceptibility to endometrial cancer, particularly among older and obese women...
  26. ncbi request reprint The association of endogenous sex steroids and sex steroid binding proteins with mammographic density: results from the Postmenopausal Estrogen/Progestin Interventions Mammographic Density Study
    Gail A Greendale
    Division of Geriatrics, David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, CA 90095 1687, USA
    Am J Epidemiol 162:826-34. 2005
    ..These results suggest that some sex steroids may increase the risk of breast cancer by stimulating breast epithelial or stromal proliferation, which appears on a mammogram as higher density...
  27. ncbi request reprint Germ line variation at 8q24 and endometrial cancer risk
    Veronica Wendy Setiawan
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Harlyne Norris Research Tower, 1450 Biggy Street, Room 1504A, Los Angeles, CA 90033, USA
    Cancer Epidemiol Biomarkers Prev 16:2166-8. 2007
  28. ncbi request reprint Lifetime recreational exercise activity and breast cancer risk among black women and white women
    Leslie Bernstein
    Department of Preventive Medicine, Keck School of Medicine, USC Norris Comprehensive Cancer Center, University of Southern California, Los Angeles, CA 90033, USA
    J Natl Cancer Inst 97:1671-9. 2005
    ....
  29. pmc Reproductive factors and breast cancer risk according to joint estrogen and progesterone receptor status: a meta-analysis of epidemiological studies
    Huiyan Ma
    Department of Preventive Medicine, Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, 1441 Eastlake Avenue 4407, Los Angeles, CA 90089, USA
    Breast Cancer Res 8:R43. 2006
    ..This report presents the first meta-analysis of results from epidemiological studies that have investigated parity, age at first birth, breastfeeding, and age at menarche in relation to ER+PR+ and ER-PR- cancer risk...
  30. pmc Long-term postmenopausal hormone therapy and endometrial cancer
    Pedram Razavi
    University of Southern California, Department of Preventive Medicine, Norris Comprehensive Cancer Center, Los Angeles, California, USA
    Cancer Epidemiol Biomarkers Prev 19:475-83. 2010
    ..These findings confirm that long-term use of ET, sequential EPT, or, among normal weight women, continuous-combined EPT is associated with increased risk of endometrial cancer...
  31. pmc Green tea, soy, and mammographic density in Singapore Chinese women
    Anna H Wu
    Department of Preventive Medicine, University of Southern California, 1441 Eastlake Avenue, Los Angeles, CA 90089, USA
    Cancer Epidemiol Biomarkers Prev 17:3358-65. 2008
    ..52). Our findings suggest that both regular green tea and high soy intake may have beneficial effects on the breast; the effect of green tea on PMD may be stronger than the effect of soy...
  32. pmc Genetic variation in transforming growth factor beta 1 and mammographic density in Singapore Chinese women
    Eunjung Lee
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
    Cancer Res 73:1876-82. 2013
    ..Our data support that TGFB1 genetic variation may be an important genetic determinant of mammographic density measure that predicts breast cancer risk, particularly in nulliparous women...
  33. pmc Evaluation of unclassified variants in the breast cancer susceptibility genes BRCA1 and BRCA2 using five methods: results from a population-based study of young breast cancer patients
    Eunjung Lee
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, 1441 Eastlake Avenue, USC Norris Comprehensive Cancer Center, Los Angeles, CA 90089 9175, USA
    Breast Cancer Res 10:R19. 2008
    ....
  34. doi request reprint The role of established breast cancer susceptibility loci in mammographic density in young women
    Eunjung Lee
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California Norris Comprehensive Cancer Center, 1441 Eastlake Avenue, Los Angeles, CA 90089, USA
    Cancer Epidemiol Biomarkers Prev 17:258-60. 2008
  35. pmc Hormone-related risk factors for breast cancer in women under age 50 years by estrogen and progesterone receptor status: results from a case-control and a case-case comparison
    Huiyan Ma
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, 1441 Eastlake Avenue, USC Norris Comprehensive Cancer Center, Los Angeles, California 90089 9175, USA
    Breast Cancer Res 8:R39. 2006
    ..It has been suggested that hormonal risk factors act predominantly on estrogen receptor and progesterone receptor (ER/PR)-positive breast cancers. However, the data have been inconsistent, especially in younger women...
  36. ncbi request reprint Low-dose medical radiation exposure and breast cancer risk in women under age 50 years overall and by estrogen and progesterone receptor status: results from a case-control and a case-case comparison
    Huiyan Ma
    Institute for Health Promotion and Disease Prevention Research, Keck School of Medicine, University of Southern California, 1000 South Fremont Avenue, Unit 8, Alhambra, CA 91803, USA
    Breast Cancer Res Treat 109:77-90. 2008
    ..We found no effect modification by ER/PR status. In conclusion, our findings support the hypothesis that low-dose ionizing radiation, and particularly exposures during childhood, increase breast cancer risk...
  37. pmc Risk factors for surgically removed fibroids in a large cohort of teachers
    Claire Templeman
    Department of Obstetrics and Gynecology, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA
    Fertil Steril 92:1436-46. 2009
    ..To describe reproductive and lifestyle correlates of surgically confirmed fibroids...
  38. pmc Breast cancer risk and ovariectomy, hysterectomy, and tubal sterilization in the women's contraceptive and reproductive experiences study
    David J Press
    Department of Preventive Medicine, Keck School of Medicine, and Norris Comprehensive Can cer Center, University of Southern California, Los Angeles, California, USA
    Am J Epidemiol 173:38-47. 2011
    ..No association with breast cancer risk was observed with tubal sterilization only or partial ovariectomy without hysterectomy. Reproductive organ surgeries may alter ovarian hormone levels, thereby affecting breast cancer risk...
  39. ncbi request reprint Serum prolactin levels are positively associated with mammographic density in postmenopausal women
    Gail A Greendale
    Division of Geriatrics, David Geffen School of Medicine at UCLA, 10945 Le Conte Avenue, Suite 2339, Los Angeles, CA 90095 1687, USA
    Breast Cancer Res Treat 105:337-46. 2007
    ..Mammographic density is a strong, independent predictor of breast cancer and, therefore, a potential surrogate indicator of breast cancer risk...
  40. pmc Menopausal hormone therapy and subsequent risk of specific invasive breast cancer subtypes in the California Teachers Study
    Tanmai Saxena
    Department of Preventive Medicine, Norris Comprehensive Cancer Center, University of Southern California Keck School of Medicine, Los Angeles, California, USA
    Cancer Epidemiol Biomarkers Prev 19:2366-78. 2010
    ....
  41. pmc Age at last birth in relation to risk of endometrial cancer: pooled analysis in the epidemiology of endometrial cancer consortium
    Veronica Wendy Setiawan
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, USA
    Am J Epidemiol 176:269-78. 2012
    ..In this large pooled analysis, late age at last birth was independently associated with a reduced risk of endometrial cancer, and the reduced risk persisted for many years...
  42. ncbi request reprint A variant in the cytochrome p450 oxidoreductase gene is associated with breast cancer risk in African Americans
    Christopher A Haiman
    Departments of Preventive Medicine and Pathology, Keck School of Medicine, University of Southern California, 1441 Eastlake Avenue, Los Angeles, CA 90089, USA
    Cancer Res 67:3565-8. 2007
    ..03) and stronger in those with advanced disease (411 cases and 877 controls; OR, 2.60; 95% CI, 1.56-4.34; P = 0.0002). These data suggest that African Americans harbor an allele at the POR locus that may increase breast cancer risk...
  43. ncbi request reprint Polymorphism in the androgen receptor and mammographic density in women taking and not taking estrogen and progestin therapy
    Elizabeth Osth Lillie
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, 1441 Eastlake Avenue, Los Angeles, CA 90089 9175, USA
    Cancer Res 64:1237-41. 2004
    ..4%) than carriers of the more active AR-CAG (25.7%; P = 0.04). Our results raise the question of whether the number of AR-CAG repeats predicts breast cancer risk in estrogen progestin therapy users...
  44. pmc Positive association between mammographic breast density and bone mineral density in the Postmenopausal Estrogen/Progestin Interventions Study
    Carolyn Crandall
    Division of General Internal Medicine, David Geffen School of Medicine at University of California, Los Angeles, CA, USA
    Breast Cancer Res 7:R922-8. 2005
    ..We hypothesized that demonstration of an association between mammographic breast density and bone mineral density (BMD) would suggest a unifying underlying mechanism influencing both breast density and BMD...
  45. ncbi request reprint Cigarette smoking is not associated with breast cancer risk in young women
    Jennifer Prescott
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089, USA
    Cancer Epidemiol Biomarkers Prev 16:620-2. 2007
  46. pmc Variation in inflammatory cytokine/growth-factor genes and mammographic density in premenopausal women aged 50-55
    Ali Ozhand
    Department of Preventive Medicine, Norris Comprehensive Cancer Center, University of Southern California Keck School of Medicine, Los Angeles, California, United States of America
    PLoS ONE 8:e65313. 2013
    ..The potential impact of genetic variation in growth factors and cytokines on MD is largely unknown...
  47. pmc Characteristics of triple-negative breast cancer in patients with a BRCA1 mutation: results from a population-based study of young women
    Eunjung Lee
    Keck School of Medicine, University of Southern California, Los Angeles, CA 90089, USA
    J Clin Oncol 29:4373-80. 2011
    ..These tumors have a poor prognosis, remain a clinical challenge, and are more common among women with BRCA1 mutations. We tested whether there are distinguishing features of TNBC after BRCA1 mutation status has been taken into account...
  48. ncbi request reprint Physical activity and colon cancer risk among women in the California Teachers Study
    Phuong L Mai
    Clinical Cancer Genetics Department, City of Hope National Medical Center, Duarte, CA, USA
    Cancer Epidemiol Biomarkers Prev 16:517-25. 2007
    ..One potential explanation for this inconsistency is that hormone therapy, which is associated with lower colon cancer risk, acts as a modifier of the physical activity/colon cancer relationship...
  49. ncbi request reprint Urinary 2-hydroxyestrone/16alpha-hydroxyestrone ratio and family history of breast cancer in premenopausal women
    Giske Ursin
    Department of Preventive Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles 90089, USA
    Breast Cancer Res Treat 72:139-43. 2002
    ..Our data suggest that among premenopausal women, family history is not associated with higher urinary estrogen levels or a lower ratio of urinary 2-OHE1/16alpha-OHE1...
  50. pmc Adenomyosis and endometriosis in the California Teachers Study
    Claire Templeman
    Department of Obstetrics and Gynecology, University of Southern California Keck School of Medicine, Los Angeles, California, USA
    Fertil Steril 90:415-24. 2008
    ..To evaluate the reproductive and lifestyle correlates of a surgically confirmed diagnosis of endometriosis or adenomyosis in a large prospective cohort...
  51. ncbi request reprint Association of new-onset breast discomfort with an increase in mammographic density during hormone therapy
    Carolyn J Crandall
    Divisions of General Internal Medicine, The David Geffen School of Medicine at UCLA, University of California Los Angeles, 911 Broxton Avenue, Los Angeles, CA 90024, USA
    Arch Intern Med 166:1578-84. 2006
    ..Postmenopausal use of estrogen and progestin therapy increases breast density and breast discomfort. Whether this increase in breast density is heralded by new-onset breast discomfort is unknown...
  52. pmc Genetic determinants of mammographic density
    Christopher A Haiman
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California 90089, USA
    Breast Cancer Res 4:R5. 2002
    ..Changes in breast density are highly correlated with steroid hormone exposure...
  53. doi request reprint Ethnic differences in the use of regular mammography: the multiethnic cohort
    Quannetta T Edwards
    Department of Clinical Cancer Genetics, City of Hope National Medical Center, Duarte, CA, USA
    Breast Cancer Res Treat 115:163-70. 2009
    ....
  54. ncbi request reprint Does menopausal hormone replacement therapy interact with known factors to increase risk of breast cancer?
    Giske Ursin
    Department of Preventive Medicine, University of Southern California Norris Comprehensive Cancer Center, Los Angeles, CA 90089, USA
    J Clin Oncol 20:699-706. 2002
    ....
  55. ncbi request reprint Induced abortion, miscarriage, and breast cancer risk of young women
    Maya Mahue-Giangreco
    Department of Preventive Medicine and Norris Comprehensive Cancer Center, Keck School of Medicine, University of Southern California, Los Angeles, California 90033, USA
    Cancer Epidemiol Biomarkers Prev 12:209-14. 2003
    ..Risk declined as the number of induced abortions increased (P = 0.04). Our results do not support the hypothesis that induced abortion or miscarriage increase the breast cancer risk of young women...
  56. pmc Dietary patterns and breast cancer risk in the California Teachers Study cohort
    Lilli B Link
    From Cancer Epidemiology, Mailman School of Public Health, Columbia University, New York, NY LBL the Cancer Prevention Institute of California, Fremont, CA AJC, CAC, and PLH R the Department of Health Research and Policy, Stanford University School of Medicine, Stanford, CA CAC and PLH R the Division of Cancer Etiology, Department of Population Sciences, Beckman Research Institute, City of Hope, Duarte, CA LB the Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA DOS and GU the Cancer Registry of Norway, Oslo, Norway GU and the Department of Nutrition, University of Oslo, Oslo, Norway GU
    Am J Clin Nutr 98:1524-32. 2013
    ..Evidence that diet is associated with breast cancer risk is inconsistent. Most studies have examined risks associated with specific foods and nutrients, rather than measures of overall diet...
  57. ncbi request reprint The association between recreational physical activity and mammographic density
    Conchitina Chato Siozon
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA 90089, USA
    Int J Cancer 119:1695-701. 2006
    ..07) and percent (p for trend = 0.08) mammographic density after adjustment for BMI. Our results suggest that physical activity is not a strong predictor of mammographic density...
  58. ncbi request reprint Associations between polymorphisms in the steroid 5-alpha reductase type II (SRD5A2) gene and benign prostatic hyperplasia and prostate cancer
    Muhammad T Salam
    Department of Preventive Medicine, University of Southern California, Los Angeles, Los Angeles, CA 90089, USA
    Urol Oncol 23:246-53. 2005
    ..03). Prostate cancer and BPH were not associated with the alanine-49 to threonine single nucleotide polymorphism and the (TA)n repeat. These results suggest that the SRD5A2 gene may play an important role in both BPH and prostate cancer...
  59. pmc The role of androgens and polymorphisms in the androgen receptor in the epidemiology of breast cancer
    Elizabeth O Lillie
    Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, California, USA
    Breast Cancer Res 5:164-73. 2003
    ..We review the quality of this evidence and conclude with a discussion of how the androgen receptor and testosterone results coincide...
  60. ncbi request reprint Dietary risk factors for ovarian cancer: the Adventist Health Study (United States)
    Fatemeh Kiani
    Department of Epidemiology and Biostatistics, Loma Linda University, Loma Linda, CA, 92350, USA
    Cancer Causes Control 17:137-46. 2006
    ..002), and also with higher fruit consumption (p < 0.01). A weak protective association was found with low fat, but not whole milk. Little confounding was observed between these foods...
  61. ncbi request reprint Association of regimens of hormone replacement therapy to prognostic factors among women diagnosed with breast cancer aged 50-64 years
    Janet R Daling
    Fred Hutchinson Cancer Research Center, Division of Public Health Sciences, Seattle, Washington 98109 1024, USA
    Cancer Epidemiol Biomarkers Prev 12:1175-81. 2003
    ....
  62. ncbi request reprint Plasma levels of enterolactone and percentage mammographic density among postmenopausal women
    Anne Stuedal
    Department of Nutrition, University of Oslo, Norway
    Cancer Epidemiol Biomarkers Prev 14:2154-9. 2005
    ..Enterolactone has been shown to have weak estrogenic and antiestrogenic properties. We decided to examine the association between plasma levels of enterolactone and mammographic density, a biomarker for breast cancer risk...
  63. ncbi request reprint Hormone replacement therapy regimens and breast cancer risk(1)
    Linda K Weiss
    Population Studies and Prevention Program, Karmanos Cancer Institute at Wayne State University, Detroit, Michigan, USA
    Obstet Gynecol 100:1148-58. 2002
    ..Progestin administered in an uninterrupted regimen may be a contributing factor. Risk dissipates once use is discontinued...
  64. ncbi request reprint Oral contraceptives and the risk of breast cancer
    Polly A Marchbanks
    Division of Reproductive Health, Centers for Disease Control and Prevention, Atlanta, USA
    N Engl J Med 346:2025-32. 2002
    ..We conducted a population-based, case-control study to determine the risk of breast cancer among former and current users of oral contraceptives...
  65. ncbi request reprint Racial differences in the familial aggregation of breast cancer and other female cancers
    Michael S Simon
    Division of Haematology and Oncology, Barbara Ann Karmanos Cancer Institute, 4100 John R, 4221 Hudson, Weber Cancer Research Building, Detroit, M1 48201, USA
    Breast Cancer Res Treat 89:227-35. 2005
    ..17 (1.22-3.85). In conclusion, these racially distinct aggregation patterns may reflect different modes of inheritance and/or environmental factors that impact cancer risk...
  66. ncbi request reprint Alcohol exposure and breast cancer: results of the women's contraceptive and reproductive experiences study
    Jill A McDonald
    National Center for Chronic Disease Prevention and Health Promotion, Division of Reproductive Health, 4770 Buford Highway Northeast, MS K22, Atlanta, GA 30341 3724, USA
    Cancer Epidemiol Biomarkers Prev 13:2106-16. 2004
    ..To explore associated biological outcomes and clarify the role of timing of exposure in the alcohol-breast cancer relationship...
  67. ncbi request reprint Infertility drugs and the risk of breast cancer: findings from the National Institute of Child Health and Human Development Women's Contraceptive and Reproductive Experiences Study
    Ronald T Burkman
    National Cancer Institute Surveillance, Epidemiology, and End Results Registry, Department of Obstetrics and Gynecology, Henry Ford Health System, Detroit, Michigan, USA
    Fertil Steril 79:844-51. 2003
    ..To determine the association between infertility drug use and invasive breast cancer in a population-based case-control study...
  68. ncbi request reprint Combined effect of oral contraceptive use and hormone replacement therapy on breast cancer risk in postmenopausal women
    Sandra A Norman
    Center for Clinical Epidemiology and Biostatistics, Department of Biostatistics and Epidemiology, University of Pennsylvania, Philadelphia, PA 19104 6021, USA
    Cancer Causes Control 14:933-43. 2003
    ..We examined breast cancer risk related to lifetime exposure to oral contraceptives (OCs) and hormone replacement therapy (HRT) in postmenopausal women...
  69. ncbi request reprint The NICHD Women's Contraceptive and Reproductive Experiences Study: methods and operational results
    Polly A Marchbanks
    Division of Reproductive Health, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Ann Epidemiol 12:213-21. 2002
    ..This paper presents methods and operational results of a population-based case-control study examining the effects of oral contraceptive use on breast cancer risk among white and black women aged 35-64 years in five U.S. locations...
  70. ncbi request reprint Relation of regimens of combined hormone replacement therapy to lobular, ductal, and other histologic types of breast carcinoma
    Janet R Daling
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, Washington 98109, USA
    Cancer 95:2455-64. 2002
    ..However, the use of combined (estrogen and progestin) hormone replacement therapy (CHRT) also has increased during the last decade and may account in part for the increase in invasive lobular breast carcinoma...
  71. ncbi request reprint Use of hormone therapy and risk of breast cancer detected at screening and between mammographic screens
    Solveig Hofvind
    The Cancer Registry of Norway, Norway
    Int J Cancer 118:3112-7. 2006
    ..The increased risk of interval cancer, which may partly be due to decreased sensitivity of mammograms in HT users, remains a challenge in breast cancer screening programs...
  72. ncbi request reprint Relationship between established breast cancer risk factors and risk of seven different histologic types of invasive breast cancer
    Christopher I Li
    Fred Hutchinson Cancer Research Center, 1100 Fairview Avenue North, M4 C308, P O Box 19024, Seattle, WA 98109 1024, USA
    Cancer Epidemiol Biomarkers Prev 15:946-54. 2006
    ....
  73. pmc Timing of menarche and first full-term birth in relation to breast cancer risk
    Christopher I Li
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA, USA
    Am J Epidemiol 167:230-9. 2008
    ..The authors conclude that the interval between age at menarche and age at first birth is associated with the risk of hormonally sensitive types of breast cancer, particularly among White women...
  74. ncbi request reprint Projecting individualized absolute invasive breast cancer risk in African American women
    Mitchell H Gail
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Executive Plaza South Rm 8032, Bethesda, MD 20892 7244, USA
    J Natl Cancer Inst 99:1782-92. 2007
    ..We developed a model for projecting absolute risk of invasive breast cancer in African American women and compared its projections with those from the Breast Cancer Risk Assessment Tool...
  75. pmc Vitamin D receptor polymorphisms and breast cancer risk in a large population-based case-control study of Caucasian and African-American women
    Britton Trabert
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Fairview Ave N, Seattle, Washington 98109 1024, USA
    Breast Cancer Res 9:R84. 2007
    ..The involvement of vitamin D receptor (VDR), which is a key mediator in the vitamin D pathway, in breast cancer etiology has long been of interest...
  76. ncbi request reprint Risk of breast cancer associated with short-term use of oral contraceptives
    Suzanne G Folger
    Division of Reproductive Health, Centers for Disease Control and Prevention, Atlanta, GA 30333, USA
    Cancer Causes Control 18:189-98. 2007
    ..To estimate breast cancer risk associated with short-term (<6 months) oral contraceptive use, and explore variation in estimates by use characteristics and medical, menstrual, and reproductive history...
  77. ncbi request reprint Insulin-like growth factor and mammographic density in postmenopausal Norwegian women
    Yngve Bremnes
    Institute of Community Medicine, University of Tromsø, N 9037 Tromsø, Norway
    Cancer Epidemiol Biomarkers Prev 16:57-62. 2007
    ..These associations were found among noncurrent hormone therapy users but not among current users...
  78. ncbi request reprint Different types of postmenopausal hormone therapy and mammographic density in Norwegian women
    Yngve Bremnes
    Institute of Community Medicine, University of Tromsø, Tromsø, Norway
    Int J Cancer 120:880-4. 2007
    ..In summary, our study shows a statistical significant positive dose-response association between current use of the continuous E(2) plus NETA combination and both measures of mammographic density...
  79. doi request reprint Does breast size modify the association between mammographic density and breast cancer risk?
    Anne Stuedal
    Department of Nutrition, University of Oslo, Oslo, Norway
    Cancer Epidemiol Biomarkers Prev 17:621-7. 2008
    ..S. women. Because African American women have a larger breast size, we assessed whether the association between mammographic density and breast cancer was less apparent in large than in small breasts...
  80. ncbi request reprint Mammographic density, hormone therapy, and risk of breast cancer
    Giske Ursin
    Cancer Epidemiol Biomarkers Prev 15:1750; author reply 1750. 2006
  81. ncbi request reprint Prevalence and predictors of BRCA1 and BRCA2 mutations in a population-based study of breast cancer in white and black American women ages 35 to 64 years
    Kathleen E Malone
    Division of Public Health Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA
    Cancer Res 66:8297-308. 2006
    ....
  82. ncbi request reprint Breast cancer risk estimates for relatives of white and African American women with breast cancer in the Women's Contraceptive and Reproductive Experiences Study
    Michael S Simon
    Division of Hematology and Oncology, Karmanos Cancer Institute at Wayne State University, Detroit, MI 48201, USA
    J Clin Oncol 24:2498-504. 2006
    ..The purpose of this report is to update breast cancer risk estimates associated with a family history of breast cancer for white and AA women...
  83. ncbi request reprint Endogenous sex hormones, prolactin and mammographic density in postmenopausal Norwegian women
    Yngve Bremnes
    Institute of Community Medicine, University of Tromsø, Tromsø, Norway
    Int J Cancer 121:2506-11. 2007
    ..Further, the authors found a positive but weak association between plasma estrone concentration and mammographic density, which appeared to be modified by IGF-I levels...
  84. ncbi request reprint Reduced mammographic density with use of a gonadotropin-releasing hormone agonist-based chemoprevention regimen in BRCA1 carriers
    Jeffrey N Weitzel
    Department of Clinical Cancer Genetics, City of Hope Cancer Center, 1500 East Duarte Road, Duarte, CA 91010, USA
    Clin Cancer Res 13:654-8. 2007
    ..We evaluated the efficacy, safety, and tolerability of hormonal chemoprevention with a gonadotropin-releasing hormone agonist (GnRHA) with low-dose add-back steroids in BRCA1(mut) carriers...
  85. ncbi request reprint Alcohol intake and breast cancer risk among young women
    Paula Berstad
    Institute of Basic Medical Sciences, Department of Nutrition, University of Oslo, Oslo, Norway
    Breast Cancer Res Treat 108:113-20. 2008
    ..Alcohol intake has been consistently associated with breast cancer risk, but the importance of timing of intake and the impact of beverage type are unclear...
  86. ncbi request reprint [Mammographic density as indicator of breast cancer risk]
    Giske Ursin
    Institutt for ernaeringsforskning, Universitetet i Oslo, Postboks 1046 Blindern, 0316 Oslo
    Tidsskr Nor Laegeforen 123:3373-6. 2003
    ..Mammographic density has been suggested as a biomarker for breast cancer risk and is currently being used as a surrogate endpoint for breast cancer in several cancer prevention trials...
  87. ncbi request reprint Absence of an effect of injectable and implantable progestin-only contraceptives on subsequent risk of breast cancer
    Brian L Strom
    Center for Clinical Epidemiology and Biostatistics and Department of Biostatistics and Epidemiology, 824 Blockley Hall, 423 Guardian Drive, University of Pennsylvania, Philadelphia, PA 19104 6021, USA
    Contraception 69:353-60. 2004
    ..This study does not support an increased risk of breast cancer associated with the use of injectable or implantable progestin-only contraceptives in women aged 35 to 64...
  88. pmc Percentage density, Wolfe's and Tabár's mammographic patterns: agreement and association with risk factors for breast cancer
    Inger T Gram
    Institute of Community Medicine, University of Tromsø, Breivika, Norway
    Breast Cancer Res 7:R854-61. 2005
    ..The purpose of this report was to classify mammograms according to four methods and to examine their agreement and their relationship to selected risk factors for breast cancer...
  89. ncbi request reprint Dietary fat and plasma total homocysteine concentrations in 2 adult age groups: the Hordaland Homocysteine Study
    Paula Berstad
    Department of Nutrition, Institute of Basic Medical Sciences, University of Oslo, Norway
    Am J Clin Nutr 85:1598-605. 2007
    ..The intake of n-3 (formerly called omega-3) fatty acids (FAs) may be inversely associated with plasma total homocysteine (tHcy) concentrations, but the epidemiologic data are sparse...

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