Research Topics
| Ergun UcSummaryAffiliation: University of Iowa Country: USA Publications
Research Grants
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Detail Information
Publications
beta-Adrenergics enhance brain extraction of levodopaErgun Y Uc
Department of Neurology, University of Arkansas for Medical Sciences, Little Rock, Arkansas, USA
Mov Disord 17:54-9. 2002..Thus, beta-adrenergic agonists might be useful in the treatment of patients with Parkinson's disease by enhancing delivery of L-dopa to the brain...- Road safety in drivers with Parkinson diseaseE Y Uc
Department of Neurology, University of Iowa, Carver College of Medicine, 200 Hawkins Drive 2RCP, Iowa City, IA 52242, USA
Neurology 73:2112-9. 2009..To assess road safety and its predictors in drivers with Parkinson disease (PD)... - Incidence of and risk factors for cognitive impairment in an early Parkinson disease clinical trial cohortE Y Uc
Department of Neurology, University of Iowa, Carver College of Medicine, 200 Hawkins Drive 2RCP, Iowa City, IA 52242, USA
Neurology 73:1469-77. 2009..To investigate the incidence of and risk factors for cognitive impairment in a large, well-defined clinical trial cohort of patients with early Parkinson disease (PD)... - Driving under low-contrast visibility conditions in Parkinson diseaseE Y Uc
Department of Neurology, University of Iowa, Carver College of Medicine, 200 Hawkins Dr, 2RCP, Iowa City, IA 52242, USA
Neurology 73:1103-10. 2009..To assess driving performance in Parkinson disease (PD) under low-contrast visibility conditions... - Driving and neurodegenerative diseasesErgun Y Uc
Department of Neurology, University of Iowa, Carver College of Medicine, 200 Hawkins Drive 2RCP, Iowa City, IA 52242, USA
Curr Neurol Neurosci Rep 8:377-83. 2008..This information will enable healthcare providers to advise their patients with neurodegenerative disorders with more certainty, affect policy, and help develop rehabilitative measures for driving... - Impaired navigation in drivers with Parkinson's diseaseErgun Y Uc
Department of Neurology, University of Iowa, Carver College of Medicine, Iowa City, IA 52242, USA
Brain 130:2433-40. 2007..Navigational errors and lower driver safety were associated more with impairments in cognitive and visual function than the motor severity of their disease in drivers with PD... - Real-life driving outcomes in Parkinson diseaseE Y Uc
Department of Neurology, University of Iowa, Carver College of Medicine, Iowa City, IA 52242, USA
Neurology 76:1894-902. 2011..To determine the incidence of and risk factors for driving outcomes in drivers with Parkinson disease (PD)... - Driving with distraction in Parkinson diseaseE Y Uc
Department of Neurology, University of Iowa, Carver College of Medicine, 200 Hawkins Drive 2RCP, Iowa City, IA 52242, USA
Neurology 67:1774-80. 2006..To assess the effects of auditory-verbal distraction on driving performance in Parkinson disease (PD)... - Unsafe rear-end collision avoidance in Alzheimer's diseaseErgun Y Uc
Division of Neuroergonomics, Department of Neurology, College of Medicice, University of Iowa Hospitals and Clinics, Iowa City, IA 52242, USA
J Neurol Sci 251:35-43. 2006..Drivers with AD had difficulty responding to driving conditions that pose a hazard for a REC. Some cognitive and visual tests were predictive of unsafe outcomes even after adjusting for disease status... - Impaired visual search in drivers with Parkinson's diseaseErgun Y Uc
Department of Neurology, Carver College of Medicine, University of Iowa, 200 Hawkins Drive 2RCP, Iowa City, IA 52242, USA
Ann Neurol 60:407-13. 2006..To assess the ability for visual search and recognition of roadside targets and safety errors during a landmark and traffic sign identification task in drivers with Parkinson's disease (PD)... - The midlatency auditory evoked potential P50 is abnormal in Huntington's diseaseErgun Y Uc
Department of Neurology, University of Arkansas for Medical Sciences and Central Arkansas Veterans Healthcare System, Little Rock, AR, USA
J Neurol Sci 212:1-5. 2003.... - Albuterol improves response to levodopa and increases skeletal muscle mass in patients with fluctuating Parkinson diseaseErgun Y Uc
Department of Neurology, University of Arkansas for Medical Sciences and Central Arkansas Veterans Healthcare System, Little Rock, AR, USA
Clin Neuropharmacol 26:207-12. 2003..A double-blind, placebo-controlled study is needed to confirm the effects and safety profile of beta(2)-agonists in PD... - Driver landmark and traffic sign identification in early Alzheimer's diseaseE Y Uc
Department of Neurology, University of Iowa Hospitals and Clinics, 200 Hawkins Drive, Iowa City, IA 52242, USA
J Neurol Neurosurg Psychiatry 76:764-8. 2005..To assess visual search and recognition of roadside targets and safety errors during a landmark and traffic sign identification task in drivers with Alzheimer's disease... - Visual dysfunction in Parkinson disease without dementiaE Y Uc
Veterans Affairs Medical Center, Department of Neurology, University of Iowa, Iowa City, IA, USA
Neurology 65:1907-13. 2005..To determine the profiles of visual dysfunction and their relationship to motor and cognitive dysfunction and to disability in mild to moderate Parkinson disease (PD) without dementia... - Predictors of weight loss in Parkinson's diseaseErgun Y Uc
Department of Neurology, Carver College of Medicine, University of Iowa, Iowa City, Iowa 52242, USA
Mov Disord 21:930-6. 2006..We demonstrated significant weight loss in PD patients compared to controls over approximately 1 decade. Neurodegeneration involving both motor and nonmotor systems may be associated with weight loss in PD... - Driver route-following and safety errors in early Alzheimer diseaseE Y Uc
Division of Neuroergonomics, Department of Neurology, College of Medicine, University of Iowa, Iowa City, IA, USA
Neurology 63:832-7. 2004..The demands of following route directions probably increased the cognitive load during driving, which might explain the higher number of safety errors... - Challenges assessing clinical endpoints in early Huntington diseaseJane S Paulsen
Department of Psychiatry, University of Iowa Carver College of Medicine, Iowa City, Iowa 52242 1000, USA
Mov Disord 25:2595-603. 2010..We conclude that future clinical trials designed for very early disease will require the development of new and more sensitive measures of real-life function... - Cerebral cortex structure in prodromal Huntington diseasePeggy C Nopoulos
Department of Psychiatry, University of Iowa Roy and Lucille Carver College of Medicine, Iowa City, IA 52242, USA
Neurobiol Dis 40:544-54. 2010..Early in the course of HD, the cortex shows changes that are manifest as cortical thinning and are most robust in the posterior and superior regions of the cerebrum... - Predictors of driving safety in early Alzheimer diseaseJ D Dawson
Department of Biostatistics, University of Iowa College of Public Health, 200 Hawkins Dr, C 22 GH, Iowa City, IA 52242, USA
Neurology 72:521-7. 2009..To measure the association of cognition, visual perception, and motor function with driving safety in Alzheimer disease (AD)... - A recommended scale for cognitive screening in clinical trials of Parkinson's diseaseKelvin L Chou
Department of Neurology, University of Michigan, Ann Arbor, Michigan 48109 5316, USA
Mov Disord 25:2501-7. 2010..Widespread adoption of a single instrument such as the MoCA in clinical trials can improve comparability between research studies on PD... - Deep brain stimulation in movement disordersErgun Y Uc
Department of Neurology, University of Iowa, Iowa City, Iowa 52242, USA
Semin Neurol 27:170-82. 2007..Bilateral procedures are more likely to cause problems with speech, cognition, and gait...
Research Grants
- Predicting Driver Safety in Parkinson's DiseaseErgun Uc; Fiscal Year: 2007..Fair and accurate means of detecting unfit drivers with PD will help mitigate the tragedy of motor vehicle crashes caused by these impaired individuals. ..