R B Turner

Summary

Affiliation: University of Virginia
Country: USA

Publications

  1. ncbi A randomized trial of the efficacy of hand disinfection for prevention of rhinovirus infection
    Ronald B Turner
    Department of Pediatrics, University of Virginia, Charlottesville, VA 22903, USA
    Clin Infect Dis 54:1422-6. 2012
  2. ncbi Treatment of the common cold with troxerutin
    Ronald B Turner
    Department of Pediatrics, University of Virginia School of Medicine, Charlottesville, VA 22908, USA
    APMIS 112:605-11. 2004
  3. ncbi An evaluation of Echinacea angustifolia in experimental rhinovirus infections
    Ronald B Turner
    University of Virginia School of Medicine, Charlottesville, VA 22908, USA
    N Engl J Med 353:341-8. 2005
  4. ncbi Virucidal hand treatments for prevention of rhinovirus infection
    Ronald B Turner
    Department of Pediatrics, University of Virginia School of Medicine, PO Box 800386, Charlottesville, VA 22908, USA
    J Antimicrob Chemother 56:805-7. 2005
  5. ncbi Studies of "natural" remedies for the common cold: pitfalls and pratfalls
    Ronald B Turner
    Department of Pediatrics, University of Virginia School of Medicine, Charlottesville, Virginia 22908, USA
    CMAJ 173:1051-2. 2005
  6. ncbi Clinical trials of herbal treatments
    Ronald B Turner
    Department of Pediatrics, University of Virginia School of Medicine, Charlottesville, Virginia 22908, USA
    Eval Health Prof 32:410-6. 2009
  7. ncbi Effectiveness of hand sanitizers with and without organic acids for removal of rhinovirus from hands
    Ronald B Turner
    Department of Pediatrics, University of Virginia School of Medicine, PO Box 800386, Charlottesville, VA 22908, USA
    Antimicrob Agents Chemother 54:1363-4. 2010
  8. ncbi Ineffectiveness of intranasal zinc gluconate for prevention of experimental rhinovirus colds
    R B Turner
    Department of Pediatrics, Medical University of South Carolina, Charleston, SC, USA
    Clin Infect Dis 33:1865-70. 2001
  9. ncbi The treatment of rhinovirus infections: progress and potential
    R B Turner
    Department of Pediatrics, Medical University of South Carolina, Clinical Sciences Building, Room 312, 171 Ashley Avenue, Charleston, SC 29425, USA
    Antiviral Res 49:1-14. 2001
  10. ncbi Efficacy of tremacamra, a soluble intercellular adhesion molecule 1, for experimental rhinovirus infection: a randomized clinical trial
    R B Turner
    Department of Pediatrics, Medical University of South Carolina, Charleston 29425, USA
    JAMA 281:1797-804. 1999

Research Grants

  1. Evalulation of Echinacea in a Human Rhinovirus Challenge
    Ronald Turner; Fiscal Year: 2003

Collaborators

Detail Information

Publications32

  1. ncbi A randomized trial of the efficacy of hand disinfection for prevention of rhinovirus infection
    Ronald B Turner
    Department of Pediatrics, University of Virginia, Charlottesville, VA 22903, USA
    Clin Infect Dis 54:1422-6. 2012
    ..The effectiveness of this intervention has not been established in a natural setting. The purpose of this study was to determine the effect of hand disinfection on RV infection and RV-associated common cold illness in a natural setting...
  2. ncbi Treatment of the common cold with troxerutin
    Ronald B Turner
    Department of Pediatrics, University of Virginia School of Medicine, Charlottesville, VA 22908, USA
    APMIS 112:605-11. 2004
    ..Based on this preliminary study, the possibility that the rutosides might provide a safe and effective treatment for rhinorrhea in the common cold deserves systematic evaluation...
  3. ncbi An evaluation of Echinacea angustifolia in experimental rhinovirus infections
    Ronald B Turner
    University of Virginia School of Medicine, Charlottesville, VA 22908, USA
    N Engl J Med 353:341-8. 2005
    ..We evaluated the effect of chemically defined extracts from Echinacea angustifolia roots on rhinovirus infection...
  4. ncbi Virucidal hand treatments for prevention of rhinovirus infection
    Ronald B Turner
    Department of Pediatrics, University of Virginia School of Medicine, PO Box 800386, Charlottesville, VA 22908, USA
    J Antimicrob Chemother 56:805-7. 2005
    ....
  5. ncbi Studies of "natural" remedies for the common cold: pitfalls and pratfalls
    Ronald B Turner
    Department of Pediatrics, University of Virginia School of Medicine, Charlottesville, Virginia 22908, USA
    CMAJ 173:1051-2. 2005
  6. ncbi Clinical trials of herbal treatments
    Ronald B Turner
    Department of Pediatrics, University of Virginia School of Medicine, Charlottesville, Virginia 22908, USA
    Eval Health Prof 32:410-6. 2009
    ..These issues must be recognized and addressed if studies of herbal remedies are to provide useful information...
  7. ncbi Effectiveness of hand sanitizers with and without organic acids for removal of rhinovirus from hands
    Ronald B Turner
    Department of Pediatrics, University of Virginia School of Medicine, PO Box 800386, Charlottesville, VA 22908, USA
    Antimicrob Agents Chemother 54:1363-4. 2010
    ..The addition of organic acids to the ethanol provided residual virucidal activity that persisted for at least 4 h. Whether these treatments will reduce rhinovirus infection in the natural setting remains to be determined...
  8. ncbi Ineffectiveness of intranasal zinc gluconate for prevention of experimental rhinovirus colds
    R B Turner
    Department of Pediatrics, Medical University of South Carolina, Charleston, SC, USA
    Clin Infect Dis 33:1865-70. 2001
    ..These data do not support a role for intranasal zinc gluconate for prevention or treatment of the common cold...
  9. ncbi The treatment of rhinovirus infections: progress and potential
    R B Turner
    Department of Pediatrics, Medical University of South Carolina, Clinical Sciences Building, Room 312, 171 Ashley Avenue, Charleston, SC 29425, USA
    Antiviral Res 49:1-14. 2001
    ..Recent advances in our understanding of the pathogenesis of common cold symptoms have provided insights into potential new targets for the treatment of this illness...
  10. ncbi Efficacy of tremacamra, a soluble intercellular adhesion molecule 1, for experimental rhinovirus infection: a randomized clinical trial
    R B Turner
    Department of Pediatrics, Medical University of South Carolina, Charleston 29425, USA
    JAMA 281:1797-804. 1999
    ..Attachment of most rhinovirus subtypes to cells depends on a cellular receptor, the intercellular adhesion molecule 1 (ICAM-1). A recombinant soluble ICAM-1 (tremacamra, formerly BIRR 4) has shown possible efficacy in early studies...
  11. ncbi Effect of treatment with zinc gluconate or zinc acetate on experimental and natural colds
    R B Turner
    Department of Pediatrics, Medical University of South Carolina, Charleston, SC 29425, USA
    Clin Infect Dis 31:1202-8. 2000
    ..Evaluation of blinding, taste, and adverse events revealed no significant differences among the 4 treatment arms. Zinc compounds appear to have little utility for common-cold treatment...
  12. ncbi Ineffectiveness of echinacea for prevention of experimental rhinovirus colds
    R B Turner
    Department of Pediatrics, Medical University of South Carolina, Charleston 29425, USA
    Antimicrob Agents Chemother 44:1708-9. 2000
    ..This preparation of echinacea had no significant effect on either the occurrence of infection or the severity of illness...
  13. ncbi Phase II, randomized, double-blind, placebo-controlled studies of ruprintrivir nasal spray 2-percent suspension for prevention and treatment of experimentally induced rhinovirus colds in healthy volunteers
    Frederick G Hayden
    Department of Internal Medicine, University of Virginia Health Sciences Center, Charlottesville, Virginia 22908, USA
    Antimicrob Agents Chemother 47:3907-16. 2003
    ..Results from these studies in experimental rhinoviral infection support continued investigation of intranasal ruprintrivir in the setting of natural HRV infection...
  14. ncbi Efficacy of organic acids in hand cleansers for prevention of rhinovirus infections
    Ronald B Turner
    University of Virginia School of Medicine, P O Box 800386, Charlottesville, VA 22908, USA
    Antimicrob Agents Chemother 48:2595-8. 2004
    ..These results suggest the feasibility of the prevention of rhinovirus transmission by hand treatments that are virucidal on contact and have activity that persists after application...
  15. ncbi Decreased rhinovirus shedding after intranasal oxymetazoline application in adults with induced colds compared with intranasal saline
    Birgit Winther
    Department of Otolaryngology, University of Virginia Health System, Charlottesville, 22908 0713, USA
    Am J Rhinol Allergy 24:374-7. 2010
    ..ICAM-1 is the major receptor used by rhinovirus to gain entry to human cells. The objective of this study was to assess the effect of OMZ on geometric mean titer of rhinovirus in nasal lavage fluid after rhinovirus inoculation...
  16. ncbi Effect of topical adrenergic decongestants on middle ear pressure in infants with common colds
    R B Turner
    Department of Pediatrics, Medical University of South Carolina, Charleston 29425, USA
    Pediatr Infect Dis J 15:621-4. 1996
    ..Otitis media is frequently a complication of the common cold. Obstruction of the eustachian tube ostia by nasopharyngeal edema has been suggested as a cause of this complication...
  17. ncbi Effectiveness of clemastine fumarate for treatment of rhinorrhea and sneezing associated with the common cold
    R B Turner
    Department of Pediatrics, Medical University of South Carolina, Charleston 29425, USA
    Clin Infect Dis 25:824-30. 1997
    ..001). This treatment effect persisted on day 4. A significant effect on sneezing was noted on days 2-4. Sedation occurred in 14% of the clemastine fumarate-treated subjects and 1.5% of the placebo-treated subjects (P < .0001)...
  18. ncbi New considerations in the treatment and prevention of rhinovirus infections
    Ronald B Turner
    University of Virginia School of Medicine, Department of Pediatrics, Charlottesville, VA 22908, USA
    Pediatr Ann 34:53-7. 2005
    ..There is no clear evidence that treatment with zinc or echinacea have any role in these infections. Interruption of transmission by handwashing remains the only method for prevention of rhinovirus infections...
  19. ncbi Effect of rhinovirus challenge on antioxidant enzymes in respiratory epithelial cells
    Poonam Kaul
    Department of Pediatrics, Medical University of South Carolina, Charleston, SC, USA
    Free Radic Res 36:1085-9. 2002
    ..These data suggest that rhinovirus-induced changes in the host cell redox state that result in the early elaboration of interleukin-8 are not mediated by inhibition of either the expression or function of these antioxidant enzymes...
  20. ncbi Assessment of adherence with medications in human immunodeficiency virus-infected children
    E Katko
    Department of Pediatrics Medical University of South Carolina Charleston, SC, USA
    Pediatr Infect Dis J 20:1174-6. 2001
    ..Adherence with at least 90% of medication doses was associated with a virologic response...
  21. ncbi NADPH oxidase in human lung fibroblasts
    Gursev S Dhaunsi
    Department of Pediatrics, Medical University of South Carolina, Charleston, SC, USA
    J Biomed Sci 11:617-22. 2004
    ....
  22. ncbi Role of NADPH oxidase in cytomegalovirus-induced proliferation of human coronary artery smooth muscle cells
    Gursev S Dhaunsi
    Department of Pediatrics, Medical University of South Carolina, Charleston, S.C, USA
    J Biomed Sci 10:505-9. 2003
    ..From this study, we conclude that CMV-mediated promotion of SMC growth is redox sensitive and may be mediated by NADPH oxidase...
  23. ncbi Rhinovirus: more than just a common cold virus
    Ronald B Turner
    J Infect Dis 195:765-6. 2007
  24. ncbi Echinacea for the common cold: can alternative medicine be evidence-based medicine?
    Ronald B Turner
    Ann Intern Med 137:1001-2. 2002
  25. ncbi Emotional style and susceptibility to the common cold
    Sheldon Cohen
    Department of Psychology, Carnegie Mellon University, Pittsburgh, PA 15213 3890, USA
    Psychosom Med 65:652-7. 2003
    ..We tested these hypotheses for host resistance to the common cold...
  26. ncbi Bioavailability and pharmacokinetics of alkamides from the roots of Echinacea angustifolia in humans
    Karin Woelkart
    Institute of Pharmaceutical Sciences, Department of Pharmacognosy, Karl-Franzens-University, Graz, Austria
    J Clin Pharmacol 45:683-9. 2005
    ..The maximum concentration of dodeca-2E,4E,8Z,10E/Z-tetraenoic acid isobutylamides, the main alkamides in the roots of E. angustifolia, appeared already after 30 minutes and was 10.88 ng/mL for the 2.5-mL dose...
  27. ncbi Objective and subjective socioeconomic status and susceptibility to the common cold
    Sheldon Cohen
    Department of Psychology, Carnegie Mellon University, Department of Otolaryngology, Pittsburgh s Children s Hospital, Pittsburgh, PA 15213, USA
    Health Psychol 27:268-74. 2008
    ..We ask whether subjective socioeconomic status (SES) predicts who develops a common cold when exposed to a cold virus...
  28. ncbi New developments in the epidemiology and clinical spectrum of rhinovirus infections
    Joshua W Brownlee
    Department of Pediatrics and Communicable Diseases, University of Michigan Medical School, Ann Arbor, Michigan, USA
    Curr Opin Pediatr 20:67-71. 2008
    ....
  29. ncbi Positive emotional style predicts resistance to illness after experimental exposure to rhinovirus or influenza a virus
    Sheldon Cohen
    Department of Psychology, Carnegie Mellon University, 5000 Forbes Avenue, Pittsburgh, PA 15213 3890
    Psychosom Med 68:809-15. 2006
    ..This work did not control for social and cognitive factors closely associated with PES. We replicate the original study using a different virus and controls for these alternative explanations...
  30. ncbi Infection-induced proinflammatory cytokines are associated with decreases in positive affect, but not increases in negative affect
    Denise Janicki-Deverts
    Department of Psychology, Carnegie Mellon University, Pittsburgh, PA, USA
    Brain Behav Immun 21:301-7. 2007
    ..There were no associations between cytokines and negative affect. Findings support a causal association between pathogen-induced local cytokine production and changes in positive affect over a 24-h timeline...
  31. ncbi Childhood socioeconomic status and host resistance to infectious illness in adulthood
    Sheldon Cohen
    Department of Psychology, Carnegie Mellon University, Pittsburgh, PA 15213, USA
    Psychosom Med 66:553-8. 2004
    ....
  32. ncbi Very long chain fatty acids activate NADPH oxidase in human dermal fibroblasts
    Gursev S Dhaunsi
    Department of Pediatrics, Faculty of Medicine, Kuwait University, Kuwait
    Cell Biochem Funct 23:65-8. 2005
    ..This study proposes a mechanism that may be taking place in vivo during peroxisomal dysfunction and that leads to oxidative stress-mediated pathogenesis...

Research Grants3

  1. Evalulation of Echinacea in a Human Rhinovirus Challenge
    Ronald Turner; Fiscal Year: 2003
    ....