Research Topics
| DENNIS TURKSummaryAffiliation: University of Washington Country: USA Publications
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Publications
Toward the identification of symptom patterns in people with fibromyalgiaHilary D Wilson
University of Washington, Seattle, WA, USA
Arthritis Rheum 61:527-34. 2009....
An examination of the psychometric structure of the Multidimensional Pain Inventory in temporomandibular disorder patients: a confirmatory factor analysisYolanda Andreu
Department of Personality, Assessment, and Psychological Treatment, University of Valencia, Spain
Head Face Med 2:48. 2006..This paper seeks to analyse the psychometric and structural properties of the Multidimensional Pain Inventory (MPI) in a sample of temporomandibular disorder patients...
An internet survey of 2,596 people with fibromyalgiaRobert M Bennett
Oregon Health and Science University, Portland, OR, USA
BMC Musculoskelet Disord 8:27. 2007....
Psychological pain treatment in fibromyalgia syndrome: efficacy of operant behavioural and cognitive behavioural treatmentsKati Thieme
Department of Clinical and Cognitive Neuroscience, University of Heidelberg, Central Institute of Mental Health, J5, 68169 Mannheim, Germany
Arthritis Res Ther 8:R121. 2006..The AP group showed that unstructured discussion of FMS-related problems may be detrimental...
Heterogeneity of psychophysiological stress responses in fibromyalgia syndrome patientsKati Thieme
Department of Neuropsychology at the University of Heidelberg, Central Institute of Mental Health, J5, 68169 Mannheim, Germany
Arthritis Res Ther 8:R9. 2006..The different psychophysiological response patterns within the patient sample support the heterogeneity of FMS...
Cognitive-behavioral approach to the treatment of chronic pain patientsDennis C Turk
Department of Anesthesiology, University of Washington, Seattle, WA 98195, USA
Reg Anesth Pain Med 28:573-9. 2003..Thus cognitive-behavioral treatments should be viewed as important complements to more traditional pharmacological, physical, and surgical interventions...
Analyzing multiple endpoints in clinical trials of pain treatments: IMMPACT recommendations. Initiative on Methods, Measurement, and Pain Assessment in Clinical TrialsDennis C Turk
Department of Anesthesiology, University of Washington, Seattle, 98195, USA
Pain 139:485-93. 2008....
Psychological approaches in the treatment of chronic pain patients--when pills, scalpels, and needles are not enoughDennis C Turk
University of Washington School of Medicine, Seattle, WA 98195 6540, USA
Can J Psychiatry 53:213-23. 2008..Chronic pain is a prevalent and costly problem that eludes adequate treatment. Persistent pain affects all domains of people's lives and in the absence of cure, success will greatly depend on adaptation to symptoms and self-management...
Assessing fear in patients with cervical pain: development and validation of the Pictorial Fear of Activity Scale-Cervical (PFActS-C)Dennis C Turk
Department of Anesthesiology, Box 356540, University of Washington, Seattle, WA 98195, USA
Pain 139:55-62. 2008..Research is needed to confirm the factor structure of the PFActS-C and to assess the generalizability of the results to other samples with neck pain...
Identifying important outcome domains for chronic pain clinical trials: an IMMPACT survey of people with painDennis C Turk
Department of Anesthesiology, University of Washington, Seattle, WA 98195, USA
Pain 137:276-85. 2008..These multiple outcomes should be considered when evaluating the efficacy and effectiveness of chronic pain treatments...
What should be the core outcomes in chronic pain clinical trials?Dennis C Turk
Department of Anesthesiology, University of Washington, Seattle, Washington, USA
Arthritis Res Ther 6:151-4. 2004..In addition, it was acknowledged that there are many secondary domains that might be of importance and should be included in trials depending on the nature of the treatment and population to whom the treatment is targeted...
Prevalence of fear of pain and activity in patients with fibromyalgia syndromeDennis C Turk
Department of Anesthesiology, University of Washington, Seattle, Washington 98195, USA
J Pain 5:483-90. 2004..This study examined the role of fear in FMS, including associations between fear of pain/movement, pain severity, depressed mood, physical performance, and disability in FMS subgroups...
The potential of treatment matching for subgroups of patients with chronic pain: lumping versus splittingDennis C Turk
Department of Anesthesiology, University of Washington, Seattle, WA 98195, USA
Clin J Pain 21:44-55; discussion 69-72. 2005..Some initial attempts to demonstrate the potential for matching treatments to patient subgroups are described...
Developing patient-reported outcome measures for pain clinical trials: IMMPACT recommendationsDennis C Turk
University of Washington, Seattle, WA 98195, USA
Pain 125:208-15. 2006
Sleep as a marker in the effective management of chronic osteoarthritis pain with opioid analgesicsDennis C Turk
John and Emma Bonica Professor of Anesthesiology and Pain Research, Department of Anesthesiology, University of Washington, Seattle, Washington 98195, USA
Semin Arthritis Rheum 39:477-90. 2010..For this purpose, available evidence evaluating the relationship between successful management of chronic pain with opioids and improvements in sleep in patients with OA is reviewed...
Chronic pain and whiplash associated disorders: rehabilitation and secondary preventionDennis C Turk
Department of Anesthesiology, University of Washington, Seattle 98195, USA
Pain Res Manag 8:40-3. 2003
Fear of pain as a prognostic factor in chronic pain: conceptual models, assessment, and treatment implicationsDennis C Turk
Department of Anesthesiology and Pain Medicine, University of Washington, Seattle, 98195, USA
Curr Pain Headache Rep 14:88-95. 2010....
Psychological factors in chronic pain: evolution and revolutionDennis C Turk
Department of Anesthesiology, University of Washington School of Medicine, Seattle 98195, USA
J Consult Clin Psychol 70:678-90. 2002..The authors conclude by noting that pain has received a tremendous amount of attention culminating in the passage of a law by the U.S. Congress designating the period 2001-2011 as the "The Decade of Pain Control and Research."..
Psychological evaluation of patients diagnosed with fibromyalgia syndrome: a comprehensive approachDennis C Turk
Department of Anesthesiology, Box 356540, University of Washington, Seattle, WA 98195, USA
Rheum Dis Clin North Am 28:219-33. 2002..Information obtained should facilitate treatment planning, specifically the matching of treatment components to the needs of individual patients...
Chronic non-malignant pain patients and health economic consequencesDennis C Turk
Department of Anesthesiology, School of Medicine, University of Washington, Seattle, WA 98195, USA
Eur J Pain 6:353-5. 2002
Cancer patients in pain: considerations for assessing the whole personDennis C Turk
Department of Anesthesiology, University of Washington, Box 356540, Seattle, WA 98195, USA
Hematol Oncol Clin North Am 16:511-25. 2002..Timely, appropriate, and thorough assessment and treatment of cancer patients experiencing pain should reduce their suffering and improve the quality of their lives...
Core outcome domains for chronic pain clinical trials: IMMPACT recommendationsDennis C Turk
Department of Anesthesiology, University of Washington, Seattle, WA 98195, USA
Pain 106:337-45. 2003....
Assessment and treatment of psychosocial comorbidities in patients with neuropathic painDennis C Turk
Department of Anesthesiology and Pain Medicine, University of Washington, Seattle, 98195, USA
Mayo Clin Proc 85:S42-50. 2010..Furthermore, psychological approaches should not be viewed as alternatives but rather should be integrated as part of a comprehensive approach to the treatment of patients with chronic neuropathic pain...
Does sex make a difference in the prescription of treatments and the adaptation to chronic pain by cancer and non-cancer patients?D C Turk
University of Washington School of Medicine, Seattle 98195, USA
Pain 82:139-48. 1999..Thus, it appears that knowing the psychological characteristics of patients may be more important than their sex...
Clinical effectiveness and cost-effectiveness of treatments for patients with chronic painDennis C Turk
Department of Anesthesiology, University of Washington, Seattle, 98195, USA
Clin J Pain 18:355-65. 2002..Chronic pain is a prevalent and costly problem. This review addresses the question of the clinical effectiveness and cost-effectiveness of the most common treatments for patients with chronic pain...
Pain, impairment, and disability in the AMA guidesJames P Robinson
Department of Rehabilitation Medicine, University of Washington, USA
J Law Med Ethics 32:315-26, 191. 2004..We conclude that a comprehensive medical evaluation of disability applicant encompasses more than an impairment assessment...
A diathesis-stress model of chronic pain and disability following traumatic injuryDennis C Turk
University of Washington, Seattle, WA 98195, USA
Pain Res Manag 7:9-19. 2002..The model is intended to be heuristic. It may be a useful conceptualization that can serve to guide prevention efforts and the development of treatment interventions...
Predictors of pain behaviors in fibromyalgia syndromeKati Thieme
Department of Anesthesiology, University of Washington, Seattle 98195 6450, USA
Arthritis Rheum 53:343-50. 2005..To evaluate the contributions of physical, pain-related, cognitive, stress-related, affective, and spouse-related variables to differences in pain behaviors in subgroups of patients with fibromyalgia syndrome (FMS)...
Stress and psychophysiological dysregulation in patients with fibromyalgia syndromeAkiko Okifuji
Division of Pain Research and Management, Department of Anesthesiology, University of Utah School of Medicine, 615 Arapeen Drive, Suite 200, Salt Lake City, Utah 84108, USA
Appl Psychophysiol Biofeedback 27:129-41. 2002..In this paper, we discuss the role of stress in the pain experience in general, stress in patients with FMS, and review the studies evaluating the ANS and HPA functions in response to various stressors...
Perceived and actual memory, concentration, and attention problems after whiplash-associated disorders (grades I and II): prevalence and predictorsJames P Robinson
Department of Physical Medicine and Rehabilitation, University of Washington, Seattle, WA 98195, USA
Arch Phys Med Rehabil 88:774-9. 2007..To evaluate neuropsychologic test performance of people with whiplash-associated disorders (WADs) and to compare the performance of those who report cognitive symptoms (CS+) with those who do not (CS-)...
Comorbid depression and anxiety in fibromyalgia syndrome: relationship to somatic and psychosocial variablesKati Thieme
Department of Anesthesiology at the University of Washington, 1959 NE Pacific Street, Box 356540, Seattle, WA 98195 6540, USA
Psychosom Med 66:837-44. 2004..The prevalence as well as predictors of psychiatric disorders (Diagnostic and Statistical Manual of Mental Disorders, 4th edition [DSM-IV] axis I and II) in patients with fibromyalgia syndrome (FMS) was evaluated...
Interpreting the clinical importance of group differences in chronic pain clinical trials: IMMPACT recommendationsRobert H Dworkin
Department of Anesthesiology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
Pain 146:238-44. 2009..Such determinations must be conducted on a case-by-case basis, and are ideally informed by patients and their significant others, clinicians, researchers, statisticians, and representatives of society at large...
Opioid pharmacotherapy for chronic non-cancer pain in the United States: a research guideline for developing an evidence-baseC Richard Chapman
Department of Anesthesiology, University of Utah School of Medicine, Salt Lake City, Utah, USA
J Pain 11:807-29. 2010..The need for a strong evidence base is urgent. This guideline offers a strategic approach to creating a comprehensive evidence base to guide safe and effective management of CNCP...
Predicting opioid misuse by chronic pain patients: a systematic review and literature synthesisDennis C Turk
Department of Anesthesiology, University of Washington, Seattle, WA, USA
Clin J Pain 24:497-508. 2008..Opioids can provide relief for people with chronic pain. However, a minority may develop aberrant drug behaviors. A critical issue is identifying "at-risk" patients...
Research design considerations for confirmatory chronic pain clinical trials: IMMPACT recommendationsRobert H Dworkin
Department of Anesthesiology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
Pain 149:177-93. 2010....
Intrathecal opioid therapy for chronic nonmalignant pain: a retrospective cohort study with 3-year follow-upAysel Atli
Department of Anesthesiology and Pain Medicine, University of Washington, Seattle, Washington 98195, USA
Pain Med 11:1010-6. 2010..Tertiary care university hospital and clinic. Patients. Adults of both sexes were included. Interventions. The intervention consisted of the implantation of intrathecal catheter and subcutaneous programmable pump to deliver opioids...
Core outcome measures for chronic pain clinical trials: IMMPACT recommendationsRobert H Dworkin
Department of Anesthesiology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
Pain 113:9-19. 2005
Development and initial validation of an expanded and revised version of the Short-form McGill Pain Questionnaire (SF-MPQ-2)Robert H Dworkin
Department of Anesthesiology, University of Rochester School of Medicine and Dentistry, 601 Elmwood Avenue, Box 604, Rochester, NY 14642, USA
Pain 144:35-42. 2009..These results provide a basis for use of the SF-MPQ-2 in future clinical research, including clinical trials of treatments for neuropathic and non-neuropathic pain conditions...
Interpreting the clinical importance of treatment outcomes in chronic pain clinical trials: IMMPACT recommendationsRobert H Dworkin
Department of Anesthesiology, University of Rochester School of Medicine and Dentistry, Rochester, New York 14642, USA
J Pain 9:105-21. 2008....
Heterogeneity within the fibromyalgia population: theoretical implications of variable tender point severity ratingsHilary D Wilson
Department of Anesthesiology and Pain Medicine, University of Washington, Seattle, Washington 98195, USA
J Rheumatol 36:2795-801. 2009..There has been little research investigating patterns of positive TP. We investigated response patterns of TP in a sample of patients with FM...
Recommendations for the pharmacological management of neuropathic pain: an overview and literature updateRobert H Dworkin
Department of Anesthesiology, University of Rochester School of Medicine and Dentistry, NY 14642, USA
Mayo Clin Proc 85:S3-14. 2010..The objectives of the current article are to review the Neuropathic Pain Special Interest Group guidelines for the pharmacological management of neuropathic pain and to provide a brief overview of these recent studies...
Sex hormones and pain in regularly menstruating women with fibromyalgia syndromeAkiko Okifuji
Pain Research Center, Department of Anesthesiology, University of Utah, Salt Lake City, Utah, USA
J Pain 7:851-9. 2006..PERSPECTIVE: Normally menstruating women with FMS and healthy women do not seem to show fluctuating threshold and tolerance to the ischemic pain test. The role of sex hormones in the hyperalgesia of FMS appears limited...
Fear of movement: factor structure of the tampa scale of kinesiophobia in patients with fibromyalgia syndromeTasha Burwinkle
Department of Anesthesiology, University of Washington, Seattle, Washington 98195, USA
J Pain 6:384-91. 2005..Recommendations for use of the TSK are provided...
Exacerbation of chronic pain following spinal cord injuryEva G Widerström-Noga
The Miami Project to Cure Paralysis, School of Medicine, University of Miami, Lois Pope LIFE Center, Miami, Florida 33136, USA
J Neurotrauma 21:1384-95. 2004..26; p < 0.05), or "electric" (t = 2.09; p < 0.05) pain, and a limited perception of life control (t = -2.16; p < 0.05) was significantly associated with a high extent of pain aggravation (R2 = 0.39; p < 0.000)...
Stability of patient adaptation classifications on the multidimensional pain inventoryJoan E Broderick
Department of Psychiatry and Behavioral Science, Putnam Hall, Stony Brook University, Stony Brook, NY 11794 8790, USA
Pain 109:94-102. 2004..As such, caution must be applied when treatment is tailored to MPI clusters and when classification change is used as an outcome measure...
Predictive value of fear avoidance in developing chronic neck pain disability: consequences for clinical decision makingMarc J Nederhand
Roessingh, Research and Development, Enschede, The Netherlands
Arch Phys Med Rehabil 85:496-501. 2004..To improve clinical decision making in posttraumatic neck pain by investigating the additional value of fear-avoidance variables in predicting chronic neck pain disability...
Understanding pain sufferers: the role of cognitive processesDennis C Turk
Spine J 4:1-7. 2004
Chronic neck pain disability due to an acute whiplash injuryMarc J Nederhand
Roessingh, Research and Development, Roessinghsbleekweg 33, 7500 AH, Enschede, The Netherlands
Pain 102:63-71. 2003..This change of motor control, is in accordance with both the (neurophysiological) 'pain adaptation model' and (cognitive behavioral) 'fear avoidance model'...
Recalled pain ratings: a complex and poorly defined taskJoan E Broderick
Department of Psychiatry and Behavioral Sciences, Stony Brook University, Stony Brook, New York 11794 8790, USA
J Pain 7:142-9. 2006..They point to the potential importance of clearly specifying what qualities of pain are sought and how the patient should summarize them over the reporting period...
Remember the distinction between malignant and benign pain? Well, forget itDennis C Turk
Clin J Pain 18:75-6. 2002
Are components of a comprehensive medical assessment predictive of work disability after an episode of occupational low back trouble?David G Hunt
Workers Compensation Board of British Columbia, Vancouver, British Columbia, Canada
Spine (Phila Pa 1976) 27:2715-9. 2002..One hundred fifty-nine subacute low back work-injured patients completed a full medical assessment at baseline. A full repeat examination was performed 3 months later, when return-to-work status was determined...
Cervical muscle dysfunction in chronic whiplash-associated disorder grade 2: the relevance of the traumaMarc J Nederhand
Roessingh, Research and Development, Enschede, The Netherlands
Spine (Phila Pa 1976) 27:1056-61. 2002..Surface electromyography measurements of the upper trapezius muscles were performed in patients with a chronic whiplash-associated disorder Grade 2 and those with nonspecific neck pain...
Behavioral and cognitive-behavioral treatment for chronic pain: outcome, predictors of outcome, and treatment processLance M McCracken
Royal National Hospital for Rheumatic Diseases and University of Bath, United Kingdom
Spine (Phila Pa 1976) 27:2564-73. 2002..A literature review was conducted...
Comparison of the redundancy, reliability, and responsiveness to change among SF-36, Oswestry Disability Index, and Multidimensional Pain InventoryHarriet Wittink
Pain Management Program, Tufts New England Medical Center, Boston, MA 02111, USA
Clin J Pain 20:133-42. 2004....
Internal consistency, stability, and validity of the spinal cord injury version of the multidimensional pain inventoryEva G Widerström-Noga
VA Medical Center, Miami, FL, USA
Arch Phys Med Rehabil 87:516-23. 2006..To evaluate the internal consistency, stability, and construct validity of a spinal cord injury (SCI) version of the Multidimensional Pain Inventory (MPI-SCI)...
The effect of fear of movement on muscle activation in posttraumatic neck pain disabilityMarc J Nederhand
Roessingh, Research and Development, Enschede, The Netherlands
Clin J Pain 22:519-25. 2006..58, P=0.011). The results support both the "pain adaptation" and the "fear avoidance" models. It is likely that the decrease in muscle activation level is aimed at "avoiding" the use of painful muscles...
American pain society recommendations for improving the quality of acute and cancer pain management: American Pain Society Quality of Care Task ForceDebra B Gordon
Department of Nursing, University of Wisconsin Hospital and Clinics, Madison 53792, USA
Arch Intern Med 165:1574-80. 2005..The American Pain Society (APS) set out to revise and expand its 1995 Quality Improvement Guidelines for the Treatment of Acute Pain and Cancer Pain and to facilitate improvements in the quality of pain management in all care settings...
Psychophysiological responses in patients with fibromyalgia syndromeKati Thieme
Department of Clinical and Cognitive Neuroscience, University of Heidelberg, Central Institute of Mental Health, Mannheim, Germany
J Psychosom Res 61:671-9. 2006..Several potential mechanisms for these psychophysiological responses are discussed...
An interdisciplinary expert consensus statement on assessment of pain in older personsThomas Hadjistavropoulos
Centre on Aging and Health, University of Regina, Regina, SK, Canada
Clin J Pain 23:S1-43. 2007..The literature underlying the consensus recommendations is reviewed. Multiple revisions led to final reviews of 2 complete drafts before consensus was reached...
Responder criteria for operant and cognitive-behavioral treatment of fibromyalgia syndromeKati Thieme
University of Heidelberg, Mannheim, Germany
Arthritis Rheum 57:830-6. 2007..To predict the effects of cognitive-behavioral therapy (CBT) and operant-behavioral therapy (OBT) in fibromyalgia syndrome (FMS)...
The biopsychosocial approach to chronic pain: scientific advances and future directionsRobert J Gatchel
Department of Psychology, University of Texas at Arlington, Arlington, TX 76063, USA
Psychol Bull 133:581-624. 2007....
Psychosocial profiles of people with pain associated with spinal cord injury: identification and comparison with other chronic pain syndromesEva G Widerström-Noga
Miami Project to Cure Paralysis, and Department of Neurological Surgery, University of Miami, FL 33136, USA
Clin J Pain 20:261-71. 2004..The objectives of the study were to: (1) identify psychosocial profiles of people with pain associated with spinal cord injuries (SCI), and (2) compare the psychosocial profiles with other chronic pain syndromes...
Psychosocial subgroups in persons with spinal cord injuries and chronic painEva G Widerström-Noga
VA Medical Center, Miami, FL, USA
Arch Phys Med Rehabil 88:1628-35. 2007....
Pharmacologic management of neuropathic pain: evidence-based recommendationsRobert H Dworkin
University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
Pain 132:237-51. 2007..Long-term studies, head-to-head comparisons between medications, studies involving combinations of medications, and RCTs examining treatment of central NP are lacking and should be a priority for future research...
Advances in neuropathic pain: diagnosis, mechanisms, and treatment recommendationsRobert H Dworkin
Department of Anesthesiology, University of Rochester School of Meedicine and Dentistry, Rochester, NY 14642
Arch Neurol 60:1524-34. 2003..Continued progress in basic and clinical research on the pathophysiologic mechanisms of neuropathic pain may make it possible to predict effective treatments for individual patients by application of a pain mechanism-based approach...
Fibromyalgia: combining pharmacological and nonpharmacological approaches to treating the person, not just the painDennis C Turk
Northwestern University, Feinberg School of Medicine, Chicago, IL 60611, USA
J Pain 9:99-104. 2008
Dextropropoxyphene: safety and efficacy in older patientsDavid J Goldstein
Department of Pharmacology and Toxicology, Indiana University School of Medicine, Indianapolis, Indiana, USA
Drugs Aging 22:419-32. 2005..Careful outcomes research is needed to assess the effectiveness and safety of dextropropoxyphene in older patients and to develop evidence-based risk/benefit prescribing criteria for use of this drug in this age group...
Core outcome domains and measures for pediatric acute and chronic/recurrent pain clinical trials: PedIMMPACT recommendationsPatrick J McGrath
Dalhousie University and IWK Health Center, Halifax, Canada
J Pain 9:771-83. 2008....
Assessment of the impact of pain and impairments associated with spinal cord injuriesEva G Widerström-Noga
Miami Project to Cure Paralysis, University of Miami School of Medicine, PO Box 01690, Miami, FL 33101, USA
Arch Phys Med Rehabil 83:395-404. 2002..To determine the adequacy of the Multidimensional Pain Inventory (MPI) for assessing pain impact after spinal cord injury (SCI) and to determine whether the impact of pain can be separated from other consequences of SCI...
The significance of clinical significanceJudith A Turner
Pain 137:467-8. 2008
Research Grants
- SUBGROUPS OF FMS--SYMPTOMS, BELIEFS & TAILORED TREATMENTDENNIS TURK; Fiscal Year: 2007..COMB treatment potentially produces the best overall outcome, since it incorporates both CR+ST, which is relevant to all participants, and ET, which is relevant to high fear participants. ..
- PREVENTING CHRONIC WHIPLASH PAIN: BIOBEHAVIORAL APPROACHDENNIS TURK; Fiscal Year: 2005..The data from this trial will provide important information about the potential of early interventions to prevent chronic problems that afflict millions of MVA victims. ..
- SUBGROUPS OF FMS--SYMPTOMS, BELIEFS & TAILORED TREATMENTDENNIS TURK; Fiscal Year: 2002..Overall, the results of these studies should establish the benefit of matching treatments to subject characteristics, and enhance our understanding of the roles of cognitive-affective-behavioral adaptation of FMS patients. ..
- SUBGROUPS OF FMS--SYMPTOMS, BELIEFS & TAILORED TREATMENTDENNIS TURK; Fiscal Year: 2009..COMB treatment potentially produces the best overall outcome, since it incorporates both CR+ST, which is relevant to all participants, and ET, which is relevant to high fear participants. ..
