Sharof M Tugizov

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint Epstein-Barr virus infection of polarized tongue and nasopharyngeal epithelial cells
    Sharof M Tugizov
    Department of Stomatology, School of Dentistry, University of California San Francisco, San Francisco, California, USA
    Nat Med 9:307-14. 2003
  2. pmc Inhibition of human papillomavirus type 16 E7 phosphorylation by the S100 MRP-8/14 protein complex
    Sharof Tugizov
    Department of Medicine, University of California, San Francisco, 513 Parnassus Ave, San Francisco, CA 94143, USA
    J Virol 79:1099-112. 2005
  3. pmc The Epstein-Barr virus BMRF-2 protein facilitates virus attachment to oral epithelial cells
    Jianqiao Xiao
    Department of Medicine, University of California, San Francisco, CA 94143 0654, USA
    Virology 370:430-42. 2008
  4. pmc EBV BMRF-2 facilitates cell-to-cell spread of virus within polarized oral epithelial cells
    Jianqiao Xiao
    Department of Medicine, University of California, San Francisco, USA
    Virology 388:335-43. 2009
  5. pmc Differential transmission of HIV traversing fetal oral/intestinal epithelia and adult oral epithelia
    Sharof M Tugizov
    Department of Medicine, University of California San Francisco, San Francisco, California, USA
    J Virol 86:2556-70. 2012
  6. pmc HIV-associated disruption of mucosal epithelium facilitates paracellular penetration by human papillomavirus
    Sharof M Tugizov
    Department of Medicine, University of California San Francisco, 513 Parnassus Ave, San Francisco, CA 94143 0512, USA Department of Orofacial Sciences, University of California San Francisco, 513 Parnassus Ave, San Francisco, CA 94143 0512, USA Electronic address
    Virology 446:378-88. 2013
  7. pmc Epstein-Barr virus transcytosis through polarized oral epithelial cells
    Sharof M Tugizov
    Department of Medicine, University of California San Francisco, San Francisco, California, USA
    J Virol 87:8179-94. 2013
  8. pmc EBV-positive human sera contain antibodies against the EBV BMRF-2 protein
    Jianqiao Xiao
    Department of Medicine, University of California, San Francisco, CA 94143 0654, USA
    Virology 393:151-9. 2009
  9. doi request reprint 46. HIV-induced epithelial-mesenchymal transition in mucosal epithelium facilitates HPV paracellular penetration
    Sharof M Tugizov
    Department of Medicine, University of California San Francisco, San Francisco, CA, USA
    Sex Health 10:592. 2013
  10. ncbi request reprint Characterization of the Epstein-Barr virus glycoprotein BMRF-2
    Jianqiao Xiao
    Department of Medicine, University of California, San Francisco, USA
    Virology 359:382-96. 2007

Research Grants

Collaborators

Detail Information

Publications12

  1. ncbi request reprint Epstein-Barr virus infection of polarized tongue and nasopharyngeal epithelial cells
    Sharof M Tugizov
    Department of Stomatology, School of Dentistry, University of California San Francisco, San Francisco, California, USA
    Nat Med 9:307-14. 2003
    ..Release of progeny virions from polarized cells occurs from both their apical and basolateral membranes. These data indicate that multiple approaches to prevention of epithelial infection with EBV will be necessary...
  2. pmc Inhibition of human papillomavirus type 16 E7 phosphorylation by the S100 MRP-8/14 protein complex
    Sharof Tugizov
    Department of Medicine, University of California, San Francisco, 513 Parnassus Ave, San Francisco, CA 94143, USA
    J Virol 79:1099-112. 2005
    ..Together these results suggests that the MRP-8/14 protein complex in HPV-infected epithelial cells may play an important role in regulation of CKII-mediated E7 phosphorylation and inhibition of its oncogenic activity...
  3. pmc The Epstein-Barr virus BMRF-2 protein facilitates virus attachment to oral epithelial cells
    Jianqiao Xiao
    Department of Medicine, University of California, San Francisco, CA 94143 0654, USA
    Virology 370:430-42. 2008
    ..These data are consistent with our previous observation that interactions between EBV BMRF-2 and integrins are critical for infection of oral epithelial cells with EBV...
  4. pmc EBV BMRF-2 facilitates cell-to-cell spread of virus within polarized oral epithelial cells
    Jianqiao Xiao
    Department of Medicine, University of California, San Francisco, USA
    Virology 388:335-43. 2009
    ..These data show that BMRF-2 may play an important role in promoting the spread of EBV progeny virions through lateral membranes of oral epithelial cells...
  5. pmc Differential transmission of HIV traversing fetal oral/intestinal epithelia and adult oral epithelia
    Sharof M Tugizov
    Department of Medicine, University of California San Francisco, San Francisco, California, USA
    J Virol 86:2556-70. 2012
    ..Transmigration of cell-free and cell-associated HIV across the fetal oral/intestinal mucosal epithelium may serve as an initial mechanism for HIV MTCT...
  6. pmc HIV-associated disruption of mucosal epithelium facilitates paracellular penetration by human papillomavirus
    Sharof M Tugizov
    Department of Medicine, University of California San Francisco, 513 Parnassus Ave, San Francisco, CA 94143 0512, USA Department of Orofacial Sciences, University of California San Francisco, 513 Parnassus Ave, San Francisco, CA 94143 0512, USA Electronic address
    Virology 446:378-88. 2013
    ..Our data suggest that HIV-associated TJ disruption of mucosal epithelia may potentiate HPV infection and subsequent development of HPV-associated neoplasia. ..
  7. pmc Epstein-Barr virus transcytosis through polarized oral epithelial cells
    Sharof M Tugizov
    Department of Medicine, University of California San Francisco, San Francisco, California, USA
    J Virol 87:8179-94. 2013
    ....
  8. pmc EBV-positive human sera contain antibodies against the EBV BMRF-2 protein
    Jianqiao Xiao
    Department of Medicine, University of California, San Francisco, CA 94143 0654, USA
    Virology 393:151-9. 2009
    ..These data indicate that RGD motif of BMRF-2 is part of an immunodominant antigenic determinant within the extracellular domain of BMRF-2 that may contribute to EBV neutralization during EBV reactivation...
  9. doi request reprint 46. HIV-induced epithelial-mesenchymal transition in mucosal epithelium facilitates HPV paracellular penetration
    Sharof M Tugizov
    Department of Medicine, University of California San Francisco, San Francisco, CA, USA
    Sex Health 10:592. 2013
    ..This facilitates entry of HPV/PsV into basal/parabasal cells, and may contribute to the increased incidence of HPV-associated malignancy in HIV-infected individuals. ..
  10. ncbi request reprint Characterization of the Epstein-Barr virus glycoprotein BMRF-2
    Jianqiao Xiao
    Department of Medicine, University of California, San Francisco, USA
    Virology 359:382-96. 2007
    ..We show that BMRF-2 is a ligand for beta1, alpha5, alpha3, and alphav integrins and our data are consistent with a role for BMRF-2 in viral lytic infection...
  11. pmc HIV-associated disruption of tight and adherens junctions of oral epithelial cells facilitates HSV-1 infection and spread
    Irna Sufiawati
    Department of Medicine, University of California San Francisco, San Francisco, California, United States of America
    PLoS ONE 9:e88803. 2014
    ..This could be one of the possible mechanisms of rapid development of HSV-associated oral lesions in HIV-infected individuals. ..
  12. pmc HIV is inactivated after transepithelial migration via adult oral epithelial cells but not fetal epithelial cells
    Sharof M Tugizov
    Department of Medicine, University of California San Francisco, 513 Parnassus Ave, San Francisco, CA 94143 0512, USA
    Virology 409:211-22. 2011
    ..Inactivation of innate proteins in adult oral keratinocytes restored HIV infectivity. These data suggest that high-level innate protein expression may contribute to the resistance of the adult oral epithelium to HIV transmission...

Research Grants2

  1. HIV AND EBV INTERACTION IN ORAL MUCOSAL EPITHELIUM
    Sharof Tugizov; Fiscal Year: 2005
    ..The results of these studies will provide new and detailed information on the mechanisms of HIV infection of the oral mucosal epithelium and the role of HIV-EBV infection in oral interepithelial LCs in HIV pathogenesis. ..
  2. EBV BMRF-2 Protein in Infection of Oral Epithelial Cells
    Sharof Tugizov; Fiscal Year: 2007
    ..These data will greatly advance knowledge of the mechanisms of EBV infection of oropharyngeal epithelial cells and may be of value to design new approaches to prevention of initial EBV infection. ..