Sharof M Tugizov

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi Epstein-Barr virus infection of polarized tongue and nasopharyngeal epithelial cells
    Sharof M Tugizov
    Department of Stomatology, School of Dentistry, University of California San Francisco, San Francisco, California, USA
    Nat Med 9:307-14. 2003
  2. ncbi Inhibition of human papillomavirus type 16 E7 phosphorylation by the S100 MRP-8/14 protein complex
    Sharof Tugizov
    Department of Medicine, University of California, San Francisco, 513 Parnassus Ave, San Francisco, CA 94143, USA
    J Virol 79:1099-112. 2005
  3. ncbi The Epstein-Barr virus BMRF-2 protein facilitates virus attachment to oral epithelial cells
    Jianqiao Xiao
    Department of Medicine, University of California, San Francisco, CA 94143 0654, USA
    Virology 370:430-42. 2008
  4. ncbi EBV BMRF-2 facilitates cell-to-cell spread of virus within polarized oral epithelial cells
    Jianqiao Xiao
    Department of Medicine, University of California, San Francisco, USA
    Virology 388:335-43. 2009
  5. ncbi Differential transmission of HIV traversing fetal oral/intestinal epithelia and adult oral epithelia
    Sharof M Tugizov
    Department of Medicine, University of California San Francisco, San Francisco, California, USA
    J Virol 86:2556-70. 2012
  6. ncbi EBV-positive human sera contain antibodies against the EBV BMRF-2 protein
    Jianqiao Xiao
    Department of Medicine, University of California, San Francisco, CA 94143 0654, USA
    Virology 393:151-9. 2009
  7. ncbi Characterization of the Epstein-Barr virus glycoprotein BMRF-2
    Jianqiao Xiao
    Department of Medicine, University of California, San Francisco, USA
    Virology 359:382-96. 2007
  8. ncbi HIV is inactivated after transepithelial migration via adult oral epithelial cells but not fetal epithelial cells
    Sharof M Tugizov
    Department of Medicine, University of California San Francisco, 513 Parnassus Ave, San Francisco, CA 94143 0512, USA
    Virology 409:211-22. 2011

Research Grants

  1. HIV AND EBV INTERACTION IN ORAL MUCOSAL EPITHELIUM
    Sharof Tugizov; Fiscal Year: 2005
  2. EBV BMRF-2 Protein in Infection of Oral Epithelial Cells
    Sharof Tugizov; Fiscal Year: 2007

Collaborators

Detail Information

Publications8

  1. ncbi Epstein-Barr virus infection of polarized tongue and nasopharyngeal epithelial cells
    Sharof M Tugizov
    Department of Stomatology, School of Dentistry, University of California San Francisco, San Francisco, California, USA
    Nat Med 9:307-14. 2003
    ..Release of progeny virions from polarized cells occurs from both their apical and basolateral membranes. These data indicate that multiple approaches to prevention of epithelial infection with EBV will be necessary...
  2. ncbi Inhibition of human papillomavirus type 16 E7 phosphorylation by the S100 MRP-8/14 protein complex
    Sharof Tugizov
    Department of Medicine, University of California, San Francisco, 513 Parnassus Ave, San Francisco, CA 94143, USA
    J Virol 79:1099-112. 2005
    ..Together these results suggests that the MRP-8/14 protein complex in HPV-infected epithelial cells may play an important role in regulation of CKII-mediated E7 phosphorylation and inhibition of its oncogenic activity...
  3. ncbi The Epstein-Barr virus BMRF-2 protein facilitates virus attachment to oral epithelial cells
    Jianqiao Xiao
    Department of Medicine, University of California, San Francisco, CA 94143 0654, USA
    Virology 370:430-42. 2008
    ..These data are consistent with our previous observation that interactions between EBV BMRF-2 and integrins are critical for infection of oral epithelial cells with EBV...
  4. ncbi EBV BMRF-2 facilitates cell-to-cell spread of virus within polarized oral epithelial cells
    Jianqiao Xiao
    Department of Medicine, University of California, San Francisco, USA
    Virology 388:335-43. 2009
    ..These data show that BMRF-2 may play an important role in promoting the spread of EBV progeny virions through lateral membranes of oral epithelial cells...
  5. ncbi Differential transmission of HIV traversing fetal oral/intestinal epithelia and adult oral epithelia
    Sharof M Tugizov
    Department of Medicine, University of California San Francisco, San Francisco, California, USA
    J Virol 86:2556-70. 2012
    ..Transmigration of cell-free and cell-associated HIV across the fetal oral/intestinal mucosal epithelium may serve as an initial mechanism for HIV MTCT...
  6. ncbi EBV-positive human sera contain antibodies against the EBV BMRF-2 protein
    Jianqiao Xiao
    Department of Medicine, University of California, San Francisco, CA 94143 0654, USA
    Virology 393:151-9. 2009
    ..These data indicate that RGD motif of BMRF-2 is part of an immunodominant antigenic determinant within the extracellular domain of BMRF-2 that may contribute to EBV neutralization during EBV reactivation...
  7. ncbi Characterization of the Epstein-Barr virus glycoprotein BMRF-2
    Jianqiao Xiao
    Department of Medicine, University of California, San Francisco, USA
    Virology 359:382-96. 2007
    ..We show that BMRF-2 is a ligand for beta1, alpha5, alpha3, and alphav integrins and our data are consistent with a role for BMRF-2 in viral lytic infection...
  8. ncbi HIV is inactivated after transepithelial migration via adult oral epithelial cells but not fetal epithelial cells
    Sharof M Tugizov
    Department of Medicine, University of California San Francisco, 513 Parnassus Ave, San Francisco, CA 94143 0512, USA
    Virology 409:211-22. 2011
    ..Inactivation of innate proteins in adult oral keratinocytes restored HIV infectivity. These data suggest that high-level innate protein expression may contribute to the resistance of the adult oral epithelium to HIV transmission...

Research Grants6

  1. HIV AND EBV INTERACTION IN ORAL MUCOSAL EPITHELIUM
    Sharof Tugizov; Fiscal Year: 2005
    ..The results of these studies will provide new and detailed information on the mechanisms of HIV infection of the oral mucosal epithelium and the role of HIV-EBV infection in oral interepithelial LCs in HIV pathogenesis. ..
  2. EBV BMRF-2 Protein in Infection of Oral Epithelial Cells
    Sharof Tugizov; Fiscal Year: 2007
    ..These data will greatly advance knowledge of the mechanisms of EBV infection of oropharyngeal epithelial cells and may be of value to design new approaches to prevention of initial EBV infection. ..