Research Topics
Genomes and Genes | Hui Ju TsaiSummaryAffiliation: University of California Country: USA Publications
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Publications
Comparison of three methods to estimate genetic ancestry and control for stratification in genetic association studies among admixed populationsHui Ju Tsai
Department of Medicine, University of California, Box 0833, San Francisco, CA, 94143 0833, USA
Hum Genet 118:424-33. 2005..These simulations are meant to provide some practical guidelines for investigators conducting association studies in admixed populations...
Admixture-matched case-control study: a practical approach for genetic association studies in admixed populationsHui Ju Tsai
Department of Medicine, Study of African American, Asthma, Genes and Environments, SAGE, University of California, 0833, San Francisco, 94143 0833, USA
Hum Genet 118:626-39. 2006..Our present work demonstrates that admixture-matched case-control strategies can efficiently control population stratification confounding in admixed populations...
Analysis of alcohol dependence phenotype in the COGA families using covariates to detect linkageBrian H Reck
Department of Human Genetics, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, USA
BMC Genet 6:S143. 2005..Linkage signals with empirical p-values less than 0.001 were detected on chromosomes 3, 4, 7, 10, and 12, with the highest peak occurring at the GABRB1 gene using the ecb21 covariate...
The PTGDR gene is not associated with asthma in 3 ethnically diverse populationsYuhjung J Tsai
University of California, San Francisco, San Francisco, CA 94143 2911, USA
J Allergy Clin Immunol 118:1242-8. 2006..The significance of PTGDR gene variants in asthma has yet to be determined in Latinos, the largest US minority population, nor has the association been replicated in other populations...
Association between IgE levels and asthma severity among African American, Mexican, and Puerto Rican patients with asthmaMariam Naqvi
University of California, San Francisco, CA 94143 2911, USA
J Allergy Clin Immunol 120:137-43. 2007..High levels of IgE are associated with asthma. Whether higher levels of IgE are associated with more severe asthma is still unclear...
CD14 tobacco gene-environment interaction modifies asthma severity and immunoglobulin E levels in Latinos with asthmaShweta Choudhry
University of California San Francisco, DNA Bank Lung Biology Center, San Francisco General Hospital, Bldg 30, 5th Floor, Room 3501H, 1001 Potrero Avenue, San Francisco, CA 94110, USA
Am J Respir Crit Care Med 172:173-82. 2005..A recent family-based genomewide screen revealed linkage between the 5q31 region and the diagnosis of asthma, but only in those exposed to environmental tobacco smoke (ETS). Among the candidate genes in this region is CD14...
Beta 2-adrenergic receptor polymorphisms: pharmacogenetic response to bronchodilator among African American asthmaticsHui Ju Tsai
Department of Medicine, University of California, San Francisco, CA 94143 0833, USA
Hum Genet 119:547-57. 2006..Our findings highlight the importance of investigating genetic risk factors for asthma in different populations...
Ethnicity-specific gene-gene interaction between IL-13 and IL-4Ralpha among African Americans with asthmaNatalie C Battle
University of California, San Francisco, San Francisco, CA 94143 2911, USA
Am J Respir Crit Care Med 175:881-7. 2007..Furthermore, interaction between these genes has been shown to affect asthma in white and Chinese populations...
Latino populations: a unique opportunity for the study of race, genetics, and social environment in epidemiological researchEsteban Gonzalez Burchard
Department of Medicine, University of California, San Francisco, CA 94143 0833, USA
Am J Public Health 95:2161-8. 2005....
Ethnic-specific differences in bronchodilator responsiveness among African Americans, Puerto Ricans, and Mexicans with asthmaMariam Naqvi
University of California, San Francisco, California 94110, USA
J Asthma 44:639-48. 2007..We conclude that ethnic-specific differences in bronchodilator drug responsiveness exist between Mexicans, Puerto Ricans, and African Americans with asthma. This may be of importance in asthma management...
