Alexander I Troster
Affiliation: University of North Carolina
- Effect of motor improvement on quality of life following subthalamic stimulation is mediated by changes in depressive symptomatologyAlexander I Troster
Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, USA
Stereotact Funct Neurosurg 80:43-7. 2003..Because depression is a potent correlate of QOL, and STN-DBS may be associated with changes in mood, this study sought to determine whether QOL improvement is a direct or indirect consequence of motor improvement...
- Pulse width is associated with cognitive decline after thalamic stimulation for essential tremorSteven Paul Woods
Department of Psychiatry and Behavioral Sciences, School of Medicine, University of Washington, Box 356560, 1959 NE Pacific Street, Seattle, WA 98195 6560, USA
Parkinsonism Relat Disord 9:295-300. 2003..Findings indicate that although relatively higher PW settings might afford optimal tremor control in some patients, the corresponding risk of mild, probably often subclinical, cognitive morbidity must be weighed accordingly...
- Verbal fluency declines after pallidotomy: an interaction between task and lesion lateralityAlexander I Troster
Department of Psychiatry and Behavioral Sciences and Department of Neurological Surgery, University of Washington, Seattle, Washington 98195 6560, USA
Appl Neuropsychol 10:69-75. 2003..Error rates (perseverations, intrusions, and rule violations) were not affected by pallidotomy. Findings support the role of left frontal-basal ganglionic circuits in word retrieval processes and/or lexical search and access...
- Prodromal frontal/executive dysfunction predicts incident dementia in Parkinson's diseaseSteven Paul Woods
Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, Washington 98195, USA
J Int Neuropsychol Soc 9:17-24. 2003..Accordingly, neuropsychological evaluation may facilitate early identification of PDD and thereby inform appropriate dispositional planning...
- Neuropsychology of deep brain stimulation in neurology and psychiatryAlexander I Troster
Department of Neurology, University of North Carolina School of Medicine at Chapel Hill, 3114 Bioinformatics Building CB 7025, Chapel Hill, NC 27599 7025, USA
Front Biosci (Landmark Ed) 14:1857-79. 2009..A minority of patients experience more widespread, persistent, or serious cognitive and psychiatric sequelae, although research to date has failed to identify reliable risk factors for such adverse events...
- Neuropsychological characteristics of dementia with Lewy bodies and Parkinson's disease with dementia: differentiation, early detection, and implications for "mild cognitive impairment" and biomarkersAlexander I Troster
Department of Neurology CB 7025, University of North Carolina at Chapel Hill, 3114 Bioinformatics Building, Chapel Hill, NC 27599 7025, USA
Neuropsychol Rev 18:103-19. 2008....
- Assessing cognitive change in Parkinson's disease: development of practice effect-corrected reliable change indicesAlexander I Troster
Department of Neurology, School of Medicine, University of North Carolina, Chapel Hill, NC 27599 7025, USA
Arch Clin Neuropsychol 22:711-8. 2007..These data may be useful to researchers and clinicians interested in determining the statistical significance of changes in cognitive test performance in persons with PD over a 1- to 2-year interval...
- Asymmetrical ventricular enlargement in Parkinson's diseaseXuemei Huang
Department of Neurology, School of Medicine, University of North Carolina, Chapel Hill, North Carolina 27599 7025, USA, and University Hospital, Vancouver, British Columbia, Canada
Mov Disord 22:1657-60. 2007..This is the first report to suggest the presence of asymmetrical ventricular enlargement in PD, findings that may be worthy of further study...
- Absence of the apolipoprotein E epsilon4 allele is associated with working memory impairment in Parkinson's diseaseAlexander I Troster
Department of Neurology, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA
J Neurol Sci 248:62-7. 2006..Additionally, results are consistent with prior findings showing an association between the epsilon4 allele and earlier onset of PD and presence of dementia...
- Apolipoprotein E and dementia in Parkinson disease: a meta-analysisXuemei Huang
Department of Neurology, University of North Carolina School of Medicine, Chapel Hill 27599 7025, USA
Arch Neurol 63:189-93. 2006..To understand the relationship of apolipoprotein E (APOE) polymorphism to dementia in Parkinson disease (PD) because the APOE epsilon4 allele is linked to Alzheimer disease...
- Quality of life in Essential Tremor Questionnaire (QUEST): development and initial validationAlexander I Troster
Department of Neurology, University of North Carolina School of Medicine, Chapel Hill, NC 27599 7025, USA
Parkinsonism Relat Disord 11:367-73. 2005..We sought to develop an ET-specific measure that might be more sensitive, acceptable to patients, relatively brief, and easily used...
- Action verbal fluency normative data for the elderlyAndrea L Piatt
Department of Psychiatry and Behavioral Sciences, University of Washington School of Medicine, Seattle, USA
Brain Lang 89:580-3. 2004..This study was undertaken to provide initial AFT normative data for a sample of 145 healthy elderly subjects. As education is significantly correlated with AFT scores, the normative data are stratified by educational level...
- The youngest reported case of corticobasal degenerationAnna DePold Hohler
Department of Neurology, Madigan Army Medical Center, Tacoma, WA, USA
Parkinsonism Relat Disord 10:47-50. 2003..The chronic, progressive course, asymmetric limb rigidity, apraxia, focal dystonia, and lack of response to levodopa suggest CBD. To our knowledge, this is the youngest reported case of clinically probable CBD...
- Declines in switching underlie verbal fluency changes after unilateral pallidal surgery in Parkinson's diseaseAlexander I Troster
Department of Psychiatry and Behavioral Sciences, School of Medicine, University of Washington, Seattle, WA, USA
Brain Cogn 50:207-17. 2002....