B J Tromberg

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Non-invasive in vivo characterization of breast tumors using photon migration spectroscopy
    B J Tromberg
    Laser Microbeam and Medical Program, Beckman Laser Institute and Medical Clinic, University of California, Irvine 92612 1475, USA
    Neoplasia 2:26-40. 2000
  2. ncbi request reprint Sources of absorption and scattering contrast for near-infrared optical mammography
    A E Cerussi
    Beckman Laser Institute and Medical Clinic, University of California, Irvine 92612, USA
    Acad Radiol 8:211-8. 2001
  3. ncbi request reprint Highly selective targeting of ovarian cancer with the photosensitizer PEG-m-THPC in a rat model
    R Hornung
    Beckman Laser Institute and Medical Clinic, University of California, Irvine, USA
    Photochem Photobiol 70:624-9. 1999
  4. doi request reprint Impact of stepwise hyperventilation on cerebral tissue oxygen saturation in anesthetized patients: a mechanistic study
    B S Alexander
    Irvine School of Medicine, University of California, Irvine, CA, USA
    Acta Anaesthesiol Scand 57:604-12. 2013
  5. pmc In vivo water state measurements in breast cancer using broadband diffuse optical spectroscopy
    S H Chung
    Beckman Laser Institute, University of California, Irvine, 1002 Health Sciences Road, Irvine, CA 92612, USA
    Phys Med Biol 53:6713-27. 2008
  6. pmc Minimally-invasive debulking of ovarian cancer in the rat pelvis by means of photodynamic therapy using the pegylated photosensitizer PEG-m-THPC
    R Hornung
    Beckman Laser Institute and Medical Clinic, University of California Irvine, 92612, USA
    Br J Cancer 81:631-7. 1999
  7. ncbi request reprint Spectroscopy enhances the information content of optical mammography
    A E Cerussi
    University of California, Irvine, Beckman Laser Institute and Medical Clinic, 1002 Health Sciences Rd, Irvine, California 92612, USA
    J Biomed Opt 7:60-71. 2002
  8. ncbi request reprint Intrauterine light probe for photodynamic ablation therapy
    Y Tadir
    Beckman Laser Institute and Medical Clinic, The Department of Obstetrics and Gynecology, University of California, Irvine 92612, USA
    Obstet Gynecol 93:299-303. 1999
  9. ncbi request reprint Monitoring tumor response during photodynamic therapy using near-infrared photon-migration spectroscopy
    T H Pham
    Laser Microbeam and Medical Program (LAMMP, Beckman Laser Institute and Medical Clinic, University of California, 1002 Health Sciences Road East, Irvine, CA 92612, USA
    Photochem Photobiol 73:669-77. 2001
  10. ncbi request reprint Comparison of water and lipid content measurements using diffuse optical spectroscopy and MRI in emulsion phantoms
    S Merritt
    Laser Microbeam and Medical Program, Beckman Laser Institute, University of California Irvine, Irvine, California 92612, USA
    Technol Cancer Res Treat 2:563-9. 2003

Collaborators

Detail Information

Publications15

  1. pmc Non-invasive in vivo characterization of breast tumors using photon migration spectroscopy
    B J Tromberg
    Laser Microbeam and Medical Program, Beckman Laser Institute and Medical Clinic, University of California, Irvine 92612 1475, USA
    Neoplasia 2:26-40. 2000
    ..Measurements provide quantitative optical property values that reflect changes in tissue perfusion, oxygen consumption, and cell/matrix development...
  2. ncbi request reprint Sources of absorption and scattering contrast for near-infrared optical mammography
    A E Cerussi
    Beckman Laser Institute and Medical Clinic, University of California, Irvine 92612, USA
    Acad Radiol 8:211-8. 2001
    ..NIR spectroscopy yields quantitative functional information that cannot be obtained with other noninvasive radiologic techniques...
  3. ncbi request reprint Highly selective targeting of ovarian cancer with the photosensitizer PEG-m-THPC in a rat model
    R Hornung
    Beckman Laser Institute and Medical Clinic, University of California, Irvine, USA
    Photochem Photobiol 70:624-9. 1999
    ..Based on these data, we are currently developing a PDT-based minimally invasive debulking technique for advanced ovarian cancer...
  4. doi request reprint Impact of stepwise hyperventilation on cerebral tissue oxygen saturation in anesthetized patients: a mechanistic study
    B S Alexander
    Irvine School of Medicine, University of California, Irvine, CA, USA
    Acta Anaesthesiol Scand 57:604-12. 2013
    ....
  5. pmc In vivo water state measurements in breast cancer using broadband diffuse optical spectroscopy
    S H Chung
    Beckman Laser Institute, University of California, Irvine, 1002 Health Sciences Road, Irvine, CA 92612, USA
    Phys Med Biol 53:6713-27. 2008
    ..These results highlight broadband DOS sensitivity to molecular disposition of water and demonstrate the potential of BWI as a non-invasive in vivo index that correlates with tissue pathology...
  6. pmc Minimally-invasive debulking of ovarian cancer in the rat pelvis by means of photodynamic therapy using the pegylated photosensitizer PEG-m-THPC
    R Hornung
    Beckman Laser Institute and Medical Clinic, University of California Irvine, 92612, USA
    Br J Cancer 81:631-7. 1999
    ..05). We conclude that PEG-m-THPC mediated PDT has a favourable therapeutic window and that this minimally-invasive procedure can reduce pelvic cancer bulks effectively and selectively...
  7. ncbi request reprint Spectroscopy enhances the information content of optical mammography
    A E Cerussi
    University of California, Irvine, Beckman Laser Institute and Medical Clinic, 1002 Health Sciences Rd, Irvine, California 92612, USA
    J Biomed Opt 7:60-71. 2002
    ..Multi-spectral measurements, compared to measurements restricted to one or two wavelengths, provide additional information that may be useful in managing breast disease...
  8. ncbi request reprint Intrauterine light probe for photodynamic ablation therapy
    Y Tadir
    Beckman Laser Institute and Medical Clinic, The Department of Obstetrics and Gynecology, University of California, Irvine 92612, USA
    Obstet Gynecol 93:299-303. 1999
    ..Photodynamic therapy requires the activation of a photosensitizer by laser light. We describe a new device specifically designed to provide light delivery to the uterus for endometrial photodynamic therapy...
  9. ncbi request reprint Monitoring tumor response during photodynamic therapy using near-infrared photon-migration spectroscopy
    T H Pham
    Laser Microbeam and Medical Program (LAMMP, Beckman Laser Institute and Medical Clinic, University of California, 1002 Health Sciences Road East, Irvine, CA 92612, USA
    Photochem Photobiol 73:669-77. 2001
    ..817 and 0.953, respectively). Overall, our results indicate that NIR FDPM spectroscopy is able to quantify noninvasively and dynamically the PDT-induced physiological effects in vivo that are highly correlated with therapeutic efficacy...
  10. ncbi request reprint Comparison of water and lipid content measurements using diffuse optical spectroscopy and MRI in emulsion phantoms
    S Merritt
    Laser Microbeam and Medical Program, Beckman Laser Institute, University of California Irvine, Irvine, California 92612, USA
    Technol Cancer Res Treat 2:563-9. 2003
    ..In addition, comparison of DOS derived concentrations to the MRI "gold standard" technique validates our quantitation approach and permits estimation of DOS accuracy and sensitivity in vivo...
  11. ncbi request reprint Broadband diffuse optical spectroscopy measurement of hemoglobin concentration during hypovolemia in rabbits
    Jangwoen Lee
    Beckman Laser Institute, University of California, Irvine, CA 92612, USA
    Physiol Meas 27:757-67. 2006
    ..Broadband DOS provides a potential platform for reliable non-invasive measurements of tissue oxygenated and deoxygenated hemoglobin and may accurately reflect the degree of systemic hypovolemia and compromised tissue perfusion...
  12. pmc Hemodynamic changes in rat leg muscles during tourniquet-induced ischemia-reperfusion injury observed by near-infrared spectroscopy
    J G Kim
    Laser Microbeam and Medical Program, Beckman Laser Institute and Medical Clinic, University of California Irvine, Irvine, USA
    Physiol Meas 30:529-40. 2009
    ..The results demonstrate that CWNIRS may be useful as a non-invasive prognostic tool for conditions involving vascular compromise such as extremity compartment syndrome...
  13. pmc Effect of phenylephrine and ephedrine bolus treatment on cerebral oxygenation in anaesthetized patients
    L Meng
    Department of Anesthesiology and Perioperative Care, University of California, Irvine Medical Center, 101 The City Drive South, Bldg 53, Rm 227, Orange, CA 92868, USA
    Br J Anaesth 107:209-17. 2011
    ..The physiological variables responsible for Sct(O2) changes induced by phenylephrine and ephedrine bolus treatment in anaesthetized patients need to be defined...
  14. ncbi request reprint Rat reproductive performance following photodynamic therapy with topically administered Photofrin
    R A Steiner
    Beckman Laser Institute and Medical Clinic, University of California, Irvine 92715, USA
    Hum Reprod 10:227-33. 1995
    ..However, Azone may enhance the selectivity of photodynamic therapy by facilitating drug targeting to critical endometrial structures...
  15. pmc Predicting bulk mechanical properties of cellularized collagen gels using multiphoton microscopy
    C B Raub
    Department of Biomedical Engineering, University of California, Irvine, CA 92697 2730, USA
    Acta Biomater 6:4657-65. 2010
    ..acellular gels. SHG and TPF image skewness and speckle contrast from cellularized collagen gels can predict E by capturing mechanically relevant information on collagen fiber, cell and crosslink density...