Emily R Troemel

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc Non-lytic, actin-based exit of intracellular parasites from C. elegans intestinal cells
    Kathleen A Estes
    Division of Biological Sciences, University of California, San Diego, La Jolla, California, United States of America
    PLoS Pathog 7:e1002227. 2011
  2. pmc Microsporidia are natural intracellular parasites of the nematode Caenorhabditis elegans
    Emily R Troemel
    Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA
    PLoS Biol 6:2736-52. 2008
  3. pmc DAF-16-dependent suppression of immunity during reproduction in Caenorhabditis elegans
    Sachiko Miyata
    Department of Molecular Biology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Genetics 178:903-18. 2008
  4. pmc Distinct pathogenesis and host responses during infection of C. elegans by P. aeruginosa and S. aureus
    Javier E Irazoqui
    Program of Developmental Immunology, Department of Pediatrics, Massachusetts General Hospital, Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, United States of America
    PLoS Pathog 6:e1000982. 2010
  5. pmc p38 MAPK regulates expression of immune response genes and contributes to longevity in C. elegans
    Emily R Troemel
    Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America
    PLoS Genet 2:e183. 2006

Research Grants

Collaborators

Detail Information

Publications7

  1. pmc Non-lytic, actin-based exit of intracellular parasites from C. elegans intestinal cells
    Kathleen A Estes
    Division of Biological Sciences, University of California, San Diego, La Jolla, California, United States of America
    PLoS Pathog 7:e1002227. 2011
    ..These results provide insight into parasite manipulation of the host cytoskeleton and non-lytic escape from intestinal cells in vivo...
  2. pmc Microsporidia are natural intracellular parasites of the nematode Caenorhabditis elegans
    Emily R Troemel
    Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA
    PLoS Biol 6:2736-52. 2008
    ..elegans and its natural microsporidian parasites provides a system in which to dissect intracellular intestinal infection in vivo and insight into the diversity of pathogenic mechanisms used by intracellular microbes...
  3. pmc DAF-16-dependent suppression of immunity during reproduction in Caenorhabditis elegans
    Sachiko Miyata
    Department of Molecular Biology, Massachusetts General Hospital, Boston, Massachusetts 02114, USA
    Genetics 178:903-18. 2008
    ..The timing of DAF-16-dependent gene activation in sterile mutants coincides with the onset of embryonic development in wild-type animals, suggesting that signals from developing embryos normally downregulate the immune response...
  4. pmc Distinct pathogenesis and host responses during infection of C. elegans by P. aeruginosa and S. aureus
    Javier E Irazoqui
    Program of Developmental Immunology, Department of Pediatrics, Massachusetts General Hospital, Department of Pediatrics, Harvard Medical School, Boston, Massachusetts, United States of America
    PLoS Pathog 6:e1000982. 2010
    ..aeruginosa nor the S. aureus-triggered response requires canonical TLR signaling, they imply the existence of unidentified mechanisms for pathogen detection in C. elegans, with potentially conserved roles also in mammals...
  5. pmc p38 MAPK regulates expression of immune response genes and contributes to longevity in C. elegans
    Emily R Troemel
    Department of Genetics, Harvard Medical School, Boston, Massachusetts, United States of America
    PLoS Genet 2:e183. 2006
    ..The contribution of the PMK-1 pathway to the enhanced lifespan of daf-2 mutants suggests that innate immunity is an important determinant of longevity...

Research Grants1

  1. A natural host model for microsporidia pathogenesis in the intestine
    Emily R Troemel; Fiscal Year: 2010
    ..This proposal employs a natural nematode host model for microsporidia pathogenesis in the intestine that has potential applicability to understanding the pathogenesis of microsporidian infections in the human intestine. ..