Madhukar H Trivedi

Summary

Affiliation: University of Texas Southwestern Medical Center
Country: USA

Publications

  1. pmc Measurement-based care for refractory depression: a clinical decision support model for clinical research and practice
    Madhukar H Trivedi
    Mood Disorders Program, Department of Psychiatry, University of Texas Southwestern Medical School, Dallas, TX 75390, USA
    Drug Alcohol Depend 88:S61-71. 2007
  2. doi request reprint Income and attrition in the treatment of depression: a STAR*D report
    Diane Warden
    Department of Psychiatry, The University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390 9086, USA
    Depress Anxiety 26:622-33. 2009
  3. ncbi request reprint Cognitive therapy versus medication in augmentation and switch strategies as second-step treatments: a STAR*D report
    Michael E Thase
    Department of Psychiatry, University of Pittsburgh Medical Center, 3811 OHara St, Pittsburgh, PA 15213 2593, and Massachusetts General Hospital, USA
    Am J Psychiatry 164:739-52. 2007
  4. doi request reprint What predicts attrition in second step medication treatments for depression?: a STAR*D Report
    Diane Warden
    Department of Psychiatry, The University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390 9119, USA
    Int J Neuropsychopharmacol 12:459-73. 2009
  5. ncbi request reprint Acceptability of second-step treatments to depressed outpatients: a STAR*D report
    Stephen R Wisniewski
    Department of Psychiatry, Epidemiology Data Center, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, and Clinical Psychopharmacology Unit, Massachusetts General Hospital, Boston, USA
    Am J Psychiatry 164:753-60. 2007
  6. ncbi request reprint Clinical and sociodemographic characteristics associated with suicidal ideation in depressed outpatients
    Madhukar H Trivedi
    Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX, USA
    Can J Psychiatry 58:113-22. 2013
  7. doi request reprint Selecting among second-step antidepressant medication monotherapies: predictive value of clinical, demographic, or first-step treatment features
    A John Rush
    Department of Psychiatry, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Blvd, Dallas, TX 75390, USA
    Arch Gen Psychiatry 65:870-80. 2008
  8. pmc Major depression symptoms in primary care and psychiatric care settings: a cross-sectional analysis
    Bradley N Gaynes
    Department of Psychiatry, University of North Carolina School of Medicine, Chapel Hill, NC 27599 7160, USA
    Ann Fam Med 5:126-34. 2007
  9. ncbi request reprint Family history of depression and therapeutic outcome: findings from STAR*D
    Mustafa M Husain
    Department of Psychiatry, University of Texas Southwestern Medical School, Dallas, TX 75390 8898, USA
    J Clin Psychiatry 70:185-95. 2009
  10. ncbi request reprint Clinical results for patients with major depressive disorder in the Texas Medication Algorithm Project
    Madhukar H Trivedi
    Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, 75235, USA
    Arch Gen Psychiatry 61:669-80. 2004

Detail Information

Publications118 found, 100 shown here

  1. pmc Measurement-based care for refractory depression: a clinical decision support model for clinical research and practice
    Madhukar H Trivedi
    Mood Disorders Program, Department of Psychiatry, University of Texas Southwestern Medical School, Dallas, TX 75390, USA
    Drug Alcohol Depend 88:S61-71. 2007
    ..Although we use major depression to illustrate our approach, the issues addressed are applicable to other chronic psychiatric conditions including comorbid depression and substance use disorder as well as other medical illnesses...
  2. doi request reprint Income and attrition in the treatment of depression: a STAR*D report
    Diane Warden
    Department of Psychiatry, The University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390 9086, USA
    Depress Anxiety 26:622-33. 2009
    ..This report assessed whether attrition rates and predictors of attrition differed among depressed outpatients with different income levels...
  3. ncbi request reprint Cognitive therapy versus medication in augmentation and switch strategies as second-step treatments: a STAR*D report
    Michael E Thase
    Department of Psychiatry, University of Pittsburgh Medical Center, 3811 OHara St, Pittsburgh, PA 15213 2593, and Massachusetts General Hospital, USA
    Am J Psychiatry 164:739-52. 2007
    ..Cognitive therapy was compared with medication augmentation and switch strategies...
  4. doi request reprint What predicts attrition in second step medication treatments for depression?: a STAR*D Report
    Diane Warden
    Department of Psychiatry, The University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390 9119, USA
    Int J Neuropsychopharmacol 12:459-73. 2009
    ..Focus on patients with attrition risk factors for medication augmentation or switch strategies may enhance retention and improve outcomes...
  5. ncbi request reprint Acceptability of second-step treatments to depressed outpatients: a STAR*D report
    Stephen R Wisniewski
    Department of Psychiatry, Epidemiology Data Center, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, and Clinical Psychopharmacology Unit, Massachusetts General Hospital, Boston, USA
    Am J Psychiatry 164:753-60. 2007
    ..This study sought to identify factors that affect patients' willingness to accept different second-step treatment approaches...
  6. ncbi request reprint Clinical and sociodemographic characteristics associated with suicidal ideation in depressed outpatients
    Madhukar H Trivedi
    Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX, USA
    Can J Psychiatry 58:113-22. 2013
    ..To identify clinical and sociodemographic characteristics associated with suicidal ideation (SI) among patients seeking care for depression in routine primary and psychiatric care settings...
  7. doi request reprint Selecting among second-step antidepressant medication monotherapies: predictive value of clinical, demographic, or first-step treatment features
    A John Rush
    Department of Psychiatry, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Blvd, Dallas, TX 75390, USA
    Arch Gen Psychiatry 65:870-80. 2008
    ..Little is known about selecting among second-step medications for major depressive disorder after intolerance or lack of remission with an initial selective serotonin reuptake inhibitor...
  8. pmc Major depression symptoms in primary care and psychiatric care settings: a cross-sectional analysis
    Bradley N Gaynes
    Department of Psychiatry, University of North Carolina School of Medicine, Chapel Hill, NC 27599 7160, USA
    Ann Fam Med 5:126-34. 2007
    ....
  9. ncbi request reprint Family history of depression and therapeutic outcome: findings from STAR*D
    Mustafa M Husain
    Department of Psychiatry, University of Texas Southwestern Medical School, Dallas, TX 75390 8898, USA
    J Clin Psychiatry 70:185-95. 2009
    ....
  10. ncbi request reprint Clinical results for patients with major depressive disorder in the Texas Medication Algorithm Project
    Madhukar H Trivedi
    Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, 75235, USA
    Arch Gen Psychiatry 61:669-80. 2004
    ..The Texas Medication Algorithm Project is an evaluation of an algorithm-based disease management program for the treatment of the self-declared persistently and seriously mentally ill in the public mental health sector...
  11. ncbi request reprint Response to a selective serotonin reuptake inhibitor (citalopram) in major depressive disorder with melancholic features: a STAR*D report
    Patrick J McGrath
    Department of Psychiatry, College of Physicians and Surgeons of Columbia University and New York State Psychiatric Institute, New York, NY 10032, USA
    J Clin Psychiatry 69:1847-55. 2008
    ....
  12. doi request reprint Sociodemographic, clinical, and treatment characteristics associated with worsened depression during treatment with citalopram: results of the NIMH STAR(*)D trial
    Edward S Friedman
    Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    Depress Anxiety 26:612-21. 2009
    ..But nonresponse can include depression that worsened over the course of treatment, an outcome that has received scant attention...
  13. ncbi request reprint Acute and longer-term outcomes in depressed outpatients requiring one or several treatment steps: a STAR*D report
    A John Rush
    Department of Psychiatry, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Blvd, Dallas, TX 75390 9086, USA
    Am J Psychiatry 163:1905-17. 2006
    ..This report describes the participants and compares the acute and longer-term treatment outcomes associated with each of four successive steps in the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) trial...
  14. doi request reprint Increase in work productivity of depressed individuals with improvement in depressive symptom severity
    Madhukar H Trivedi
    Department of Psychiatry, University of Texas Southwestern Medical Center at Dallas, USA
    Am J Psychiatry 170:633-41. 2013
    ..The authors sought to identify baseline clinical and sociodemographic characteristics associated with work productivity in depressed outpatients and to assess the effect of treatment on work productivity...
  15. pmc Primary versus specialty care outcomes for depressed outpatients managed with measurement-based care: results from STAR*D
    Bradley N Gaynes
    Department of Psychiatry, University of North Carolina School of Medicine, Chapel Hill, NC, USA
    J Gen Intern Med 23:551-60. 2008
    ..Whether the acute outcomes of major depressive disorder (MDD) treated in primary (PC) or specialty care (SC) settings are different is unknown...
  16. ncbi request reprint Predictors of attrition during initial (citalopram) treatment for depression: a STAR*D report
    Diane Warden
    Department of Psychiatry, The University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390 9086, USA
    Am J Psychiatry 164:1189-97. 2007
    ..The purpose of this study was to identify the pretreatment predictors of attrition during acute treatment with citalopram in a large, "real world" clinical trial...
  17. doi request reprint Clinical correlates of the worsening or emergence of suicidal ideation during SSRI treatment of depression: an examination of citalopram in the STAR*D study
    Sidney Zisook
    Department of Psychiatry, University of California, San Diego, San Diego VA Medical Center, San Diego, California, USA
    J Affect Disord 117:63-73. 2009
    ..The purpose of this study was to determine whether, and in whom, treatment of MDD is associated with increased or emergent SI...
  18. ncbi request reprint Prevention of recurrent episodes of depression with venlafaxine ER in a 1-year maintenance phase from the PREVENT Study
    James H Kocsis
    Department of Psychiatry, Weill Cornell Medical College, New York, NY 10012, USA
    J Clin Psychiatry 68:1014-23. 2007
    ..To test the long-term efficacy and safety of venlafaxine extended-release (ER) in preventing recurrence in patients with major depression...
  19. ncbi request reprint Medication augmentation after the failure of SSRIs for depression
    Madhukar H Trivedi
    Mood Disorder Program and Clinic, Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX 75390 9119, USA
    N Engl J Med 354:1243-52. 2006
    ..Although clinicians frequently add a second medication to an initial, ineffective antidepressant drug, no randomized controlled trial has compared the efficacy of this approach...
  20. ncbi request reprint Effect of age at onset on the course of major depressive disorder
    Sidney Zisook
    Department of Psychiatry, University of California, San Diego, CA 92093, USA
    Am J Psychiatry 164:1539-46. 2007
    ..This report assesses whether age at onset defines a specific subgroup of major depressive disorder in 4,041 participants who entered the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) study...
  21. pmc Predictors of attrition during one year of depression treatment: a roadmap to personalized intervention
    Diane Warden
    Department of Psychiatry, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Blvd, Dallas, TX 75390 9119, USA
    J Psychiatr Pract 15:113-24. 2009
    ..To assist in tailoring the delivery of interventions to specific patients to reduce attrition, this study reports the incidence, timing, and predictors of attrition from outpatient treatment in public mental health clinics...
  22. ncbi request reprint Health-related quality of life in depression: a STAR*D report
    Ella J Daly
    Department of Psychiatry, University of Texas Southwestern Medical School at Dallas, 5323 Harry Hines Blvd, Dallas, TX 75390 9119, USA
    Ann Clin Psychiatry 22:43-55. 2010
    ..This report examined the psychological, physical, and social domains in a large sample of outpatients who entered the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) trial...
  23. pmc Remission of maternal depression: relations to family functioning and youth internalizing and externalizing symptoms
    Cynthia Ewell Foster
    Department of Psychiatry, University of Michigan, Ann Arbor, MI 48105, USA
    J Clin Child Adolesc Psychol 37:714-24. 2008
    ..9% of the variance...
  24. pmc Sex differences in depression symptoms in treatment-seeking adults: confirmatory analyses from the Sequenced Treatment Alternatives to Relieve Depression study
    Sheila M Marcus
    Department of Psychiatry, University of Michigan Medical School, Ann Arbor, MI 48105, USA
    Compr Psychiatry 49:238-46. 2008
    ..This article examines sex differences in terms of illness attributes in a cohort of 2541 outpatients from across the United States who enrolled in the Sequenced Treatment Alternatives to Relieve Depression study...
  25. pmc Chronic forms of major depression are still undertreated in the 21st century: systematic assessment of 801 patients presenting for treatment
    James H Kocsis
    Department of Psychiatry, Weill Cornell Medical Center, 525 East 68th Street, New York, NY 10021, USA
    J Affect Disord 110:55-61. 2008
    ..These results and the consistency of similar results over time point to the dire need for patient and provider education regarding the signs and symptoms of depression and its treatment...
  26. pmc Assessing anxious features in depressed outpatients
    Shawn M McClintock
    Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX 75390 8898, USA
    Int J Methods Psychiatr Res 20:e69-82. 2011
    ..Both the HRSD(ANX) and IDS-C(ANX) subscales have acceptable psychometric properties and can be used to identify anxious features for clinical or research purposes...
  27. ncbi request reprint Texas Medication Algorithm Project, phase 3 (TMAP-3): clinical results for patients with a history of mania
    Trisha Suppes
    Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, 75390 9070, USA
    J Clin Psychiatry 64:370-82. 2003
    ....
  28. ncbi request reprint An empirical analysis of cost outcomes of the Texas Medication Algorithm Project
    T Michael Kashner
    Department of Psychiatry at the University of Texas Southwestern Medical Center, Dallas, TX 75390 9086, USA
    Psychiatr Serv 57:648-59. 2006
    ..The Texas Medication Algorithm Project was designed to compare health care costs and clinical outcomes between patients who received algorithm-guided medication management or usual care in 19 public mental health clinics...
  29. ncbi request reprint Sequenced treatment alternatives to relieve depression (STAR*D): rationale and design
    A John Rush
    Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9086, USA
    Control Clin Trials 25:119-42. 2004
    ..Participants with an adequate symptomatic response may enter the 12-month naturalistic follow-up phase with brief monthly and more complete quarterly assessments...
  30. ncbi request reprint Evaluation of outcomes with citalopram for depression using measurement-based care in STAR*D: implications for clinical practice
    Madhukar H Trivedi
    Department of Psychiatry, University of Texas Southwestern Medical Center, Exchange Park Express, American General Tower, 6363 Forest Park Rd, Suite 1300, Dallas, TX 75390 9119, USA
    Am J Psychiatry 163:28-40. 2006
    ....
  31. doi request reprint Randomized comparison of selective serotonin reuptake inhibitor (escitalopram) monotherapy and antidepressant combination pharmacotherapy for major depressive disorder with melancholic features: a CO-MED report
    William V Bobo
    Department of Psychiatry, Vanderbilt University School of Medicine, Nashville, TN, USA
    J Affect Disord 133:467-76. 2011
    ..The clinical effects of antidepressant combinations vs. monotherapy as initial treatment for major depression with melancholic features (MDD-MF) are unknown...
  32. pmc Baseline depression severity as a predictor of single and combination antidepressant treatment outcome: results from the CO-MED trial
    Edward S Friedman
    Department of Psychiatry, University of Pittsburgh School of Medicine, PA, USA
    Eur Neuropsychopharmacol 22:183-99. 2012
    ..03). These data may help us to understand the impact of baseline features on antidepressant medication effectiveness and to inform the personalization of depression treatment across the spectrum of depressive severity...
  33. ncbi request reprint Insomnia in patients with depression: a STAR*D report
    Prabha Sunderajan
    Department of Psychiatry, UT Southwestern Medical Center, Dallas, TX 75390 9119, USA
    CNS Spectr 15:394-404. 2010
    ..However, little is known about the prevalence and associated features of insomnia symptoms in representative treatment-seeking patients with depression...
  34. ncbi request reprint Factors associated with health-related quality of life among outpatients with major depressive disorder: a STAR*D report
    Madhukar H Trivedi
    Department of Psychiatry, University of Texas UT Southwestern Medical Center, Dallas 75390 9119, and the Clinical Psychopharmacology Unit, Massachusetts General Hospital, Boston, USA
    J Clin Psychiatry 67:185-95. 2006
    ..The aim of this study was to examine sociodemographic and clinical correlates of HRQOL in a large cohort of outpatients with MDD...
  35. ncbi request reprint Self-reported depressive symptom measures: sensitivity to detecting change in a randomized, controlled trial of chronically depressed, nonpsychotic outpatients
    A John Rush
    Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX 75390 9086, USA
    Neuropsychopharmacology 30:405-16. 2005
    ..Global patient ratings such as the PGI-I, as opposed to specific item-based ratings, provide less valid findings...
  36. pmc Assessing physicians' use of treatment algorithms: Project IMPACTS study design and rationale
    Madhukar H Trivedi
    Department of Psychiatry, The University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390 9119, USA
    Contemp Clin Trials 28:192-212. 2007
    ..These new procedures and data points will also allow a more refined assessment of algorithm-driven treatment in the future...
  37. doi request reprint Factors predicting reduced antidepressant response: experience with the SNRI duloxetine in patients with major depression
    Robert H Howland
    Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    Ann Clin Psychiatry 20:209-18. 2008
    ..To identify putative demographic and clinical variables that correlate with antidepressant response to the SNRI duloxetine in major depression...
  38. ncbi request reprint Bupropion-SR, sertraline, or venlafaxine-XR after failure of SSRIs for depression
    A John Rush
    Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX 75390 9086, USA
    N Engl J Med 354:1231-42. 2006
    ..After unsuccessful treatment for depression with a selective serotonin-reuptake inhibitor (SSRI), it is not known whether switching to one antidepressant is more effective than switching to another...
  39. doi request reprint What did STAR*D teach us? Results from a large-scale, practical, clinical trial for patients with depression
    Bradley N Gaynes
    Department of Psychiatry, University of North Carolina School of Medicine, Chapel Hill, NC 27599, USA
    Psychiatr Serv 60:1439-45. 2009
    ..STAR*D demonstrated that inclusion of more real-world patients in clinical trials is both feasible and informative. Policy implications of the findings, as well as the study's limitations, are discussed...
  40. doi request reprint Exercise as an augmentation treatment for nonremitted major depressive disorder: a randomized, parallel dose comparison
    Madhukar H Trivedi
    Division on Mood Disorders, Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX 75390 9119, USA
    J Clin Psychiatry 72:677-84. 2011
    ..The Treatment with Exercise Augmentation for Depression (TREAD) study was designed to test the efficacy of aerobic exercise as an augmentation treatment for MDD patients who had not remitted with antidepressant treatment...
  41. ncbi request reprint Sensory correlations in autism
    Janet K Kern
    University of Texas, Southwestern Medical Center, Dallas, TX 75390, USA
    Autism 11:123-34. 2007
    ....
  42. pmc Identifying risk for attrition during treatment for depression
    Diane Warden
    Department of Psychiatry, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Blvd, Dallas, TX 75390 9119, USA
    Psychother Psychosom 78:372-9. 2009
    ..Understanding patients' ambivalence about treatment persistence may be useful in tailoring retention interventions for individual patients with major depressive disorder...
  43. pmc Psychometric properties of the Quick Inventory of Depressive Symptomatology in adolescents
    Ira H Bernstein
    Department of Psychiatry, The University of Texas Southwestern Medical Center, Dallas, TX 75390 9066, USA
    Int J Methods Psychiatr Res 19:185-94. 2010
    ..This study evaluated both versions of the QIDS and the 17-item Children's Depressive Rating Scale - Revised (CDRS-R) in an adolescent outpatient sample...
  44. ncbi request reprint TREAD: TReatment with Exercise Augmentation for Depression: study rationale and design
    Madhukar H Trivedi
    Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, Texas, USA
    Clin Trials 3:291-305. 2006
    ..However, no randomized controlled trials have evaluated exercise as an augmentation strategy for patients with carefully diagnosed MDD who remain symptomatic following an adequate acute phase trial of antidepressant therapy...
  45. ncbi request reprint Factors associated with concomitant psychotropic drug use in the treatment of major depression: a STAR*D Report
    Rchard C Shelton
    Department of Psychiatry, Vanderbilt University, Nashville, TN 37212, USA
    CNS Spectr 14:487-98. 2009
    ..Concomitant psychotropic medication (CPM) treatment is common in persons with major depression (MDD). However, relationships with patient characteristics and response to treatment are unclear...
  46. ncbi request reprint Insured and non-insured depressed outpatients: how do they compare?
    Ira M Lesser
    Department of Psychiatry, Harbor UCLA Medical Center, The Los Angeles Biomedical Research Institute, Los Angeles, CA, USA
    Ann Clin Psychiatry 19:73-82. 2007
    ....
  47. ncbi request reprint Maximizing the adequacy of medication treatment in controlled trials and clinical practice: STAR(*)D measurement-based care
    Madhukar H Trivedi
    Department of Psychiatry, University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390, USA
    Neuropsychopharmacology 32:2479-89. 2007
    ..This approach signals a paradigm shift toward the use of measurement-based clinical decisions, both at the point of care and following each visit, to deliver optimal pharmacotherapy for depression...
  48. ncbi request reprint REVAMP - Research Evaluating the Value of Augmenting Medication with Psychotherapy: rationale and design
    Madhukar H Trivedi
    Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX, USA
    Psychopharmacol Bull 41:5-33. 2008
    ....
  49. doi request reprint Concise Associated Symptoms Tracking scale: a brief self-report and clinician rating of symptoms associated with suicidality
    Madhukar H Trivedi
    Department of Psychiatry, The University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390 9119, USA
    J Clin Psychiatry 72:765-74. 2011
    ....
  50. doi request reprint Concise Health Risk Tracking scale: a brief self-report and clinician rating of suicidal risk
    Madhukar H Trivedi
    Department of Psychiatry, The University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390 9086, USA
    J Clin Psychiatry 72:757-64. 2011
    ..This report evaluates the psychometric properties of a brief self- and clinician-rated measure of factors related to the risk of suicide attempt or completion...
  51. pmc Cognitive behavioral analysis system of psychotherapy and brief supportive psychotherapy for augmentation of antidepressant nonresponse in chronic depression: the REVAMP Trial
    James H Kocsis
    Department of Psychiatry, Weill Cornell Medical College, 1300 York Ave, New York, NY 10065, USA
    Arch Gen Psychiatry 66:1178-88. 2009
    ..Previous studies have found that few chronically depressed patients remit with antidepressant medications alone...
  52. pmc Psychosocial outcomes in patients with recurrent major depressive disorder during 2 years of maintenance treatment with venlafaxine extended release
    Madhukar H Trivedi
    University of Texas Southwestern Medical School, Dallas, Texas 75235, United States
    J Affect Disord 126:420-9. 2010
    ..Psychosocial outcomes from the Prevention of Recurrent Episodes of Depression with Venlafaxine ER for Two Years (PREVENT) study were evaluated...
  53. doi request reprint Diurnal mood variation in outpatients with major depressive disorder
    David W Morris
    Mood Disorders Program and Clinic, Department of Psychiatry, University of Texas Southwestern Medical Center, Exchange Park Express, American General Tower, 6363 Forest Park Road, Suite 13 354, Dallas, TX 75390 9119, USA
    Depress Anxiety 26:851-63. 2009
    ..This report used data from the sequenced treatment alternatives to relieve depression study to determine whether DMV was associated with treatment outcome to citalopram...
  54. ncbi request reprint Clinical features of depressed outpatients with and without co-occurring general medical conditions in STAR*D
    William R Yates
    Department of Psychiatry, University of Oklahoma College of Medicine, Tulsa, OK 74135, USA
    Gen Hosp Psychiatry 26:421-9. 2004
    ..A significant percentage of patients with major depressive disorder (MDD) suffer from concurrent general medical conditions (GMCs)...
  55. pmc Early adverse events and attrition in selective serotonin reuptake inhibitor treatment: a suicide assessment methodology study report
    Diane Warden
    Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX 75390 9119, USA
    J Clin Psychopharmacol 30:259-66. 2010
    ..Neither global ratings nor specific adverse effects at week 2 were related to patient attrition during SSRI treatment. Other factors seem to contribute to patient decisions about continuing with treatment...
  56. ncbi request reprint Continuation treatment of chronic depression: a comparison of nefazodone, cognitive behavioral analysis system of psychotherapy, and their combination
    James H Kocsis
    Department of Psychiatry, Weill Cornell Medical College, New York, NY 10021, USA
    Psychopharmacol Bull 37:73-87. 2003
    ..COMB was associated with less symptom re-emergence during the continuation phase than either monotherapy, particularly for partial remitters...
  57. ncbi request reprint Adjunctive aripiprazole in major depressive disorder: analysis of efficacy and safety in patients with anxious and atypical features
    Madhukar H Trivedi
    UT Southwestern Medical Center at Dallas, 5323 Harry Hines Blvd, Dallas, TX 75390 9119, USA
    J Clin Psychiatry 69:1928-36. 2008
    ..To evaluate the efficacy of adjunctive aripiprazole to standard antidepressant therapy (ADT) for patients with DSM-IV major depressive disorder with anxious/atypical features at baseline...
  58. ncbi request reprint An integrated analysis of olanzapine/fluoxetine combination in clinical trials of treatment-resistant depression
    Madhukar H Trivedi
    Department of Psychiatry, University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390 9119, USA
    J Clin Psychiatry 70:387-96. 2009
    ..To evaluate the efficacy of olanzapine/fluoxetine combination (OFC) versus olanzapine or fluoxetine monotherapy across all clinical trials of treatment-resistant depression sponsored by Eli Lilly and Company...
  59. pmc Residual symptoms in depressed outpatients who respond by 50% but do not remit to antidepressant medication
    Shawn M McClintock
    Department of Psychiatry, University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390 8898, USA
    J Clin Psychopharmacol 31:180-6. 2011
    ..Individualized treatments are warranted to specifically address each patient's residual depressive symptoms...
  60. ncbi request reprint Diurnal mood variation in outpatients with major depressive disorder: implications for DSM-V from an analysis of the Sequenced Treatment Alternatives to Relieve Depression Study data
    David W Morris
    Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX 75390 9119, USA
    J Clin Psychiatry 68:1339-47. 2007
    ....
  61. doi request reprint STAR*D: revising conventional wisdom
    A John Rush
    Department of Clinical Sciences, University of Texas Southwestern Medical Center, Dallas, Texas, USA
    CNS Drugs 23:627-47. 2009
    ..Although switch and augmentation strategies could not be directly compared due to the equipoise stratified randomized design, the higher remission rates at step 2 with medication augmentation are intriguing and merit further study...
  62. ncbi request reprint Use of treatment algorithms for depression
    Madhukar H Trivedi
    Mood Disorders Program and Clinic, Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX, USA
    J Clin Psychiatry 67:1458-65. 2006
  63. pmc A psychometric evaluation of the CDRS and MADRS in assessing depressive symptoms in children
    Shailesh Jain
    Department of Psychiatry, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA
    J Am Acad Child Adolesc Psychiatry 46:1204-12. 2007
    ..This study compared the psychometric properties of the Children's Depression Rating Scale-Revised (CDRS-R) and the Montgomery-Asberg Depression Rating Scale (MADRS) in children with major depressive disorder...
  64. ncbi request reprint Clinical evidence and potential neurobiological underpinnings of unresolved symptoms of depression
    Madhukar H Trivedi
    Department of Psychiatry, University of Texas Southwestern Medical Center at Dallas, TX 75235, USA
    J Clin Psychiatry 69:246-58. 2008
    ..This article reviews research on the current understanding and management of residual symptoms, i.e., subthreshold depressive symptoms present after recovery from a major depressive episode...
  65. ncbi request reprint Report by the ACNP Task Force on response and remission in major depressive disorder
    A John Rush
    Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX 75390 9086, USA
    Neuropsychopharmacology 31:1841-53. 2006
    ..Research to evaluate these recommendations empirically is needed...
  66. ncbi request reprint Comorbid psychiatric disorders in depressed outpatients: demographic and clinical features
    A John Rush
    Department of Psychiatry, The University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390 9086, USA
    J Affect Disord 87:43-55. 2005
    ..This study evaluated the clinical and sociodemographic features associated with various degrees of concurrent comorbidity in adult outpatients with nonpsychotic major depressive disorder (MDD)...
  67. ncbi request reprint Pain in depression: STAR*D study findings
    Mustafa M Husain
    Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX 75390 8898, USA
    J Psychosom Res 63:113-22. 2007
    ..Pain complaints commonly accompany major depressive disorder (MDD). However, whether patients with MDD and pain complaints differ from those without pain complaints is not well studied...
  68. ncbi request reprint Randomized, placebo-controlled trial of nefazodone maintenance treatment in preventing recurrence in chronic depression
    Alan J Gelenberg
    Department of Psychiatry, Health Sciences Center, University of Arizona, PO Box 245002, Tucson, AZ 85724 5002, USA
    Biol Psychiatry 54:806-17. 2003
    ..This randomized, placebo-controlled study of the efficacy and safety of nefazodone in preventing recurrence was conducted for patients with chronic MDD...
  69. ncbi request reprint Symptomatic and syndromal anxiety in chronic forms of major depression: effect of nefazodone, cognitive behavioral analysis system of psychotherapy, and their combination
    Philip T Ninan
    Department of Psychiatry, Emory University School of Medicine, Atlanta, GA 30329, USA
    J Clin Psychiatry 63:434-41. 2002
    ....
  70. ncbi request reprint Background and rationale for the sequenced treatment alternatives to relieve depression (STAR*D) study
    Maurizio Fava
    Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA
    Psychiatr Clin North Am 26:457-94, x. 2003
    ..This article provides the overall rationale for STAR*D and details the rationale for key design, measurement, and analytic features of the study...
  71. ncbi request reprint Differential effects of nefazodone and cognitive behavioral analysis system of psychotherapy on insomnia associated with chronic forms of major depression
    Michael E Thase
    Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, PA 15213 2593, USA
    J Clin Psychiatry 63:493-500. 2002
    ..As nefazodone-mediated blockade of serotonin-2 receptors may directly relieve insomnia associated with depression, we examined the more specific effects of CBASP and nefazodone, singly and in combination, on sleep disturbances...
  72. ncbi request reprint Sexual function and satisfaction in the treatment of chronic major depression with nefazodone, psychotherapy, and their combination
    John Zajecka
    Department of Psychiatry, Rush Presbyterian St Luke s Medical Center, 1725 W Harrison Street, Suite 955, Chicago, IL 60612, USA
    J Clin Psychiatry 63:709-16. 2002
    ..This study compares the effects of antidepressant medication, psychotherapy, and combined treatment on sexual interest/satisfaction and function in patients with chronic major depression...
  73. ncbi request reprint Remission of depression and the Texas Medication Algorithm Project
    Madhukar H Trivedi
    Depression and Anxiety Disorders Program, University of Texas, Southwestern Medical Center, Dallas, USA
    Manag Care Interface . 2003
  74. ncbi request reprint Consensus recommendations for improving adherence, self-management, and outcomes in patients with depression
    Madhukar H Trivedi
    Mood Disorders Program, Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX, USA
    CNS Spectr 12:1-27. 2007
    ....
  75. ncbi request reprint The DOSE study: a clinical trial to examine efficacy and dose response of exercise as treatment for depression
    Andrea L Dunn
    Division of Research, The Cooper Institute, Dallas, TX 75230, USA
    Control Clin Trials 23:584-603. 2002
    ..This study is the first to examine dose-response effects of exercise in participants diagnosed with MDD...
  76. pmc Telephone-based assessments to minimize missing data in longitudinal depression trials: a project IMPACTS study report
    Cindy Claassen
    University of Texas Southwestern Medical Center, Dallas, Texas 75390 9119, USA
    Contemp Clin Trials 30:13-9. 2009
    ..We developed longitudinal assessment procedures that included telephone-based clinician interviews in order to minimize missing data commonly encountered with face-to-face assessment procedures...
  77. ncbi request reprint Treating depression complicated by comorbid medical illness or anxiety
    Madhukar H Trivedi
    Department of Psychiatry and Mood Disorders Research Program and Clinic, University of Texas Southwestern Medical Center, Dallas, USA
    J Clin Psychiatry 68:e01. 2007
    ....
  78. doi request reprint Defining and measuring functional recovery from depression
    Tracy L Greer
    Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9119, USA
    CNS Drugs 24:267-84. 2010
    ..The development of treatments that specifically target improvements in functional impairments is needed, and may require the use of novel treatment strategies...
  79. pmc Strategies to enhance the therapeutic efficacy of antidepressants: targeting residual symptoms
    Benji T Kurian
    Department of Psychiatry, The University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390 9119, USA
    Expert Rev Neurother 9:975-84. 2009
    ..This article reviews the prevalence and clinical impact of common residual symptoms and discusses the utility of aggressively addressing residual symptoms to enhance the efficacy of antidepressant medications...
  80. pmc The Montgomery Asberg and the Hamilton ratings of depression: a comparison of measures
    Thomas J Carmody
    Department of Psychiatry, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd Dallas, TX 75390 9086, United States
    Eur Neuropsychopharmacol 16:601-11. 2006
    ..An HRSD(17) of 7 corresponded to an 8 or 9 on the MADRS and 4 on the HRSD(6). The MADRS would be superior to the HRSD(17) in the conduct of clinical trials...
  81. doi request reprint Tools and strategies for ongoing assessment of depression: a measurement-based approach to remission
    Madhukar H Trivedi
    Department of Psychiatry, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Blvd, Dallas, TX 75390 9119, USA
    J Clin Psychiatry 70:26-31. 2009
    ....
  82. doi request reprint Abnormal brain response to cholinergic challenge in chronic encephalopathy from the 1991 Gulf War
    Robert W Haley
    Epidemiology Division, Departments of Internal Medicine and Clinical Science, University of Texas Southwestern Medical Center, Dallas, TX, USA
    Psychiatry Res 171:207-20. 2009
    ..95 and specificity of 0.82. Gulf War-associated chronic encephalopathy in a subset of veterans may be due to neuronal dysfunction, including abnormal cholinergic response, in deep brain structures...
  83. ncbi request reprint Datapoints: rates of nonfatal intentional self-harm in nine states, 2001
    Cynthia A Claassen
    Department of Psychiatry, University of Texas Southwestern Medical Center, 5323 Harry Hines, Dallas, Texas 75390 9119, USA
    Psychiatr Serv 57:313. 2006
  84. ncbi request reprint Clinical differences among depressed patients with and without a history of suicide attempts: findings from the STAR*D trial
    Cynthia A Claassen
    Department of Psychiatry and Division of Clinical Psychology, University of Texas Southwestern Medical School, Dallas, Texas 75235 9119, United States
    J Affect Disord 97:77-84. 2007
    ....
  85. ncbi request reprint Voice response system to measure healthcare costs: a STAR*D report
    T Michael Kashner
    Department of Psychiatry, University of Texas Southwestern, 5323 Harry Hines Blvd, Dallas, TX 75390 9086, USA
    Am J Manag Care 15:153-62. 2009
    ..To evaluate a telephone-operated, interactive voice response (IVR) system designed to collect use-of-care data from patients with major depression (UAC-IVR)...
  86. ncbi request reprint Remissions in maternal depression and child psychopathology: a STAR*D-child report
    Myrna M Weissman
    Department of Psychiatry, Columbia University and the New York State Psychiatric Institute, New York 10032, USA
    JAMA 295:1389-98. 2006
    ..Children of depressed parents have high rates of anxiety, disruptive, and depressive disorders that begin early, often continue into adulthood, and are impairing...
  87. ncbi request reprint Treatment-resistant depression: new therapies on the horizon
    Madhukar H Trivedi
    Depression and Anxiety Disorders Program, The University of Texas, Southwestern Medical School, Dallas, Texas, USA
    Ann Clin Psychiatry 15:59-70. 2003
    ..This kind of therapeutic intervention may prove to be especially useful in treating patients with TRD...
  88. doi request reprint Developing a neuropsychiatric functional brain imaging test
    F Andrew Kozel
    Department of Psychiatry, University of Texas Southwestern Medical Center, 5323 Harry Hines Blvd, Dallas, TX 75390 9119, USA
    Neurocase 14:54-8. 2008
    ..Incorporating what has been learned with medical diagnostic test development will enable legitimate and significant neuropsychiatric functional brain imaging tests to be developed in the future...
  89. pmc Psychometric evaluation of the Snaith-Hamilton pleasure scale in adult outpatients with major depressive disorder
    Paul A Nakonezny
    Department of Clinical Sciences, Division of Biostatistics, The University of Texas Southwestern Medical Center, Dallas, TX 75390 8828, USA
    Int Clin Psychopharmacol 25:328-33. 2010
    ..65, P<0.0001). This study shows that the SHAPS is a reliable, valid, and unidimensional instrument used to assess the hedonic capacity in adult outpatients with MDD...
  90. doi request reprint Treatment outcomes for older depressed patients with earlier versus late onset of first depressive episode: a Sequenced Treatment Alternatives to Relieve Depression (STAR*D) report
    F Andrew Kozel
    Department of Psychiatry, University of Texas Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390, USA
    Am J Geriatr Psychiatry 16:58-64. 2008
    ..In this study of older depressed outpatients, the authors evaluated whether the age at onset of the first major depressive episode (MDE) was related to clinical outcomes...
  91. ncbi request reprint Cost and effectiveness of venlafaxine extended-release and selective serotonin reuptake inhibitors in the acute phase of outpatient treatment for major depressive disorder
    Madhukar H Trivedi
    Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX 75390 9119, USA
    J Clin Psychopharmacol 24:497-506. 2004
    ..The purpose of this retrospective analysis was to estimate the cost and effectiveness of venlafaxine extended-release (VXR) compared with selective serotonin reuptake inhibitors in the outpatient treatment of major depressive disorder...
  92. ncbi request reprint Clinicians' adherence to an algorithm for pharmacotherapy of depression in the Texas public mental health sector
    Tawny L Bettinger
    College of Pharmacy, The University of Texas at Austin, 78712, USA
    Psychiatr Serv 55:703-5. 2004
    ..The results suggest that implementation of medication algorithms is possible in the public mental health sector...
  93. ncbi request reprint Chronic depression: medication (nefazodone) or psychotherapy (CBASP) is effective when the other is not
    Alan F Schatzberg
    Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94305 5717, USA
    Arch Gen Psychiatry 62:513-20. 2005
    ..Although various strategies are available to manage nonresponders to an initial treatment for depression, no controlled trials address the utility of switching from an antidepressant medication to psychotherapy or vice versa...
  94. ncbi request reprint The Prevention of Recurrent Episodes of Depression with Venlafaxine for Two Years (PREVENT) Study: Outcomes from the 2-year and combined maintenance phases
    Martin B Keller
    Department of Psychiatry and Human Behavior, Brown University, Providence, RI 02906, USA
    J Clin Psychiatry 68:1246-56. 2007
    ..To report second-year results from the 2-year maintenance phase of a long-term study to evaluate the efficacy and safety of venlafaxine extended release (ER) in preventing recurrence of depression...
  95. ncbi request reprint Children of currently depressed mothers: a STAR*D ancillary study
    Daniel J Pilowsky
    Columbia University and the New York State Psychiatric Institute, 1051 Riverside Drive, New York, NY 10032, USA
    J Clin Psychiatry 67:126-36. 2006
    ....
  96. ncbi request reprint The effects of psychotherapy, nefazodone, and their combination on subjective assessment of disturbed sleep in chronic depression
    Rachel Manber
    Department of Psychiatry and Behavioral Sciences, Stanford University, CA 94305, USA
    Sleep 26:130-6. 2003
    ..The purpose of the study was to compare the effects of psychotherapy, nefazodone, and their combination on subjective measures of sleep in patients with chronic forms of major depression...
  97. ncbi request reprint Prevalence and clinical correlates of irritability in major depressive disorder: a preliminary report from the Sequenced Treatment Alternatives to Relieve Depression study
    Roy H Perlis
    Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    J Clin Psychiatry 66:159-66; quiz 147, 273-4. 2005
    ..Irritability with or without depression has been associated with risk for suicide, violence, and cardiovascular disease...
  98. ncbi request reprint Clinical correlates and symptom patterns of anxious depression among patients with major depressive disorder in STAR*D
    Maurizio Fava
    Depression Clinical and Research Program, Massachusetts General Hospital, Boston, MA 02114, USA
    Psychol Med 34:1299-308. 2004
    ..Anxious depression, defined as Major Depressive Disorder (MDD) with high levels of anxiety symptoms, may represent a relatively common depressive subtype, with distinctive features...
  99. ncbi request reprint Does psychosocial functioning improve independent of depressive symptoms? A comparison of nefazodone, psychotherapy, and their combination
    Robert M A Hirschfeld
    Department of Psychiatry and Behavioral Sciences, University of Texas Medical Branch, Galveston, Texas 77555 0188, USA
    Biol Psychiatry 51:123-33. 2002
    ..This study compared efficacy of nefazodone, psychotherapy, and their combination in improving psychosocial functioning in chronically depressed outpatients...
  100. pmc Faster remission of chronic depression with combined psychotherapy and medication than with each therapy alone
    Rachel Manber
    Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94305, USA
    J Consult Clin Psychol 76:459-67. 2008
    ..The authors conclude that combined antidepressant medications and psychotherapy result in faster full remission of chronic forms of major depressive disorder...
  101. ncbi request reprint Association between treatment-emergent suicidal ideation with citalopram and polymorphisms near cyclic adenosine monophosphate response element binding protein in the STAR*D study
    Roy H Perlis
    Massachusetts General Hospital, Boston, MA 02114, USA
    Arch Gen Psychiatry 64:689-97. 2007
    ....