Research Topics
Genomes and GenesSpecies | Taylor M TrioloSummaryAffiliation: University of Colorado Denver Country: USA Publications
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Publications
Diabetic subjects diagnosed through the Diabetes Prevention Trial-Type 1 (DPT-1) are often asymptomatic with normal A1C at diabetes onsetTaylor M Triolo
University of Colorado Denver, Barbara Davis Center for Childhood Diabetes, Aurora, Colorado, USA
Diabetes Care 32:769-73. 2009..Metabolic tests and the presence of symptoms were described at diabetes onset during the Diabetes Prevention Trial-Type 1 (DPT-1)...
Additional autoimmune disease found in 33% of patients at type 1 diabetes onsetTaylor M Triolo
Barbara Davis Center for Childhood Diabetes, Aurora, Colorado, USA
Diabetes Care 34:1211-3. 2011..We sought to define the prevalence of nonislet, organ-specific autoantibodies at diagnosis of type 1 diabetes and to determine the prevalence of comorbid autoimmune diseases...
Dominant suppression of Addison's disease associated with HLA-B15Peter R Baker
Barbara Davis Center for Childhood Diabetes, University of Colorado Denver, Aurora, Colorado 80045 6511, USA
J Clin Endocrinol Metab 96:2154-62. 2011..Highest genetic risk is associated with the Major Histocompatibility region (MHC), specifically human leukocyte antigen (HLA)-DR3 haplotypes (containing HLA-B8) and HLA-DR4...
Haplotype analysis discriminates genetic risk for DR3-associated endocrine autoimmunity and helps define extreme risk for Addison's diseasePeter R Baker
Barbara Davis Center for Childhood Diabetes, University of Colorado Denver, Aurora, Colorado 80045 6511, USA
J Clin Endocrinol Metab 95:E263-70. 2010..Multiple autoimmune disorders (e.g. Addison's disease, type 1 diabetes, celiac disease) are associated with HLA-DR3, but it is likely that alleles of additional genes in linkage disequilibrium with HLA-DRB1 contribute to disease...
Homozygosity of the polymorphism MICA5.1 identifies extreme risk of progression to overt adrenal insufficiency among 21-hydroxylase antibody-positive patients with type 1 diabetesTaylor M Triolo
Barbara Davis Center for Childhood Diabetes, University of Colorado Denver, Health Science Center, Aurora, CO 80045, USA
J Clin Endocrinol Metab 94:4517-23. 2009..Subjects with type 1 diabetes (T1D) are at increased risk for AD. Genetic factors including HLA-DRB1*0404 and MICA have been associated with AD in populations with and without T1D...
Two single nucleotide polymorphisms identify the highest-risk diabetes HLA genotype: potential for rapid screeningJennifer M Barker
Barbara Davis Center for Childhood Diabetes, University of Coloradoat Denver, Colorado, USA
Diabetes 57:3152-5. 2008..We sought to find an inexpensive, rapid test to identify DR3/4-DQ8 subjects using two single nucleotide polymorphisms (SNPs)...
