Maurizio Trevisan

..The aim of this study was to examine the association between various drinking patterns and myocardial infarction (MI)...

..In this study, we examined breast cancer risk in relation to exposure to air pollution from traffic emissions throughout life...

..Overall, we found no evidence that these common polymorphisms of the MTHFR and MTR genes are associated with promoter methylation of E-cadherin, p16, and RAR-beta2 genes in breast cancer...

..The mechanism of the observed association between body mass, particularly centralized body fat, and postmenopausal breast cancer risk is not well understood...

..Our results suggest that there are time periods of weight gain that have greater impact on risk, and that central body fat, receptor status and hormone replacement therapy may all affect the observed association...

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..Reduced rank regression (RRR) has been used to identify dietary patterns that predict variation in a selected risk factor and may be useful in describing dietary exposures associated with glycemic index (GI) and glycemic load (GL)...

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..This finding, however, does not exclude the possibility that intake of such nutrients might have the ability to modulate promoter methylation in normal or premalignant (dysplastic) breast tissue...

..50-3.59). Increased risk was limited to estrogen receptor-positive tumors. Our findings suggest that CAT genotype modifies the effect of HRT use on breast cancer risk and that HRT may affect risk by affecting oxidative stress...

..To examine whether several biomarkers of endothelial function and inflammation improve prediction of type 2 diabetes over 5.9 years of follow-up, independent of traditional risk factors...

..g., drinking frequency during the week and in relation to food consumption)...

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..05, CI = 0.95-4.43, P = 0.07). Consistent with previous studies, we found that mtDNA mutations are a frequent occurrence in breast tumors. An understanding of the etiology of mtDNA mutations may provide insight into breast carcinogenesis...

..Our study suggests that exposure in early life to high levels of PAHs may increase the risk of postmenopausal breast cancer; however, other confounders related to geography cannot be ruled out...

..In this study, exposure to SHS either in adult or early life does not appear to be associated with the risk of breast cancer...

..In summary, our results suggest that higher lignan intakes may be associated with improved survival among postmenopausal women with breast cancer...

..This study investigates whether periodontal disease is related to recurrent CVD events and mortality in survivors of incident myocardial infarction (MI)...

..Better understanding of the role of COX-2 genetic variation and interaction with NSAID use in breast carcinogenesis has potential to inform prevention strategies...

..These results indicate that some of the variants in BER and NER genes may influence risk of postmenopausal breast cancer...

..Therefore, we sought to test the association between lifetime cumulative exposure to SHS and risk of myocardial infarction (MI) (as an indication of CHD) among never smokers...

..28, 95% CI: 1.04-1.57), as well as luminal A or B breast cancers. These findings support the hypothesis of heterogeneous etiologies of breast cancer subtypes and that aspirin and ibuprofen vary in their effects...

..Findings from animal models suggest that selenium supplementation improves glucose metabolism...

..40; 95% confidence interval, 0.16-1.01). Our findings suggest that, although CLA intake was not related to overall breast cancer risk, there may be associations with tumor biology at least among premenopausal women...

..80; 95% CI, 1.03-3.28) compared with nondrinkers who were homozygote CC. Our findings indicate that among postmenopausal women, increased breast cancer risk with alcohol consumption may be as a result of effects on one-carbon metabolism...

..Limited data have been reported in women and the role of smoking has not been fully clarified...

..These results suggest that oxidative stress may be associated with airflow limitation in men, and that gender differences may exist in the relation of oxidative stress to pulmonary function...

..While there is accumulating evidence that use of nonsteroidal anti-inflammatory drugs (NSAID) decreases breast cancer risk, little is known about the impact of NSAIDs on survival after breast cancer diagnosis...

..To determine whether cigarette smoking is associated with the conversion from normoglycemia to impaired fasting glucose (IFG)...

..There is increasing evidence that early life exposures, such as birth weight, infant feeding practices, birth rank and maternal age at delivery may play a role in breast carcinogenesis...

..In conclusion, these findings support a role for central adiposity independent from BMI in predicting increased levels of hepatic enzymes, likely as a result of unrecognized fatty liver...

..Since an increased RBC distribution width (RDW) has been associated with nutritional deficiencies, we postulated that RDW has an inverse relation to pulmonary function. The purpose of this study was to test this hypothesis...

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..In conclusion, drinking outside meals appears to have a significant effect on hypertension risk independent of the amount of alcohol consumed...

..We analyzed the relation of beverage-specific alcohol intake with forced expiratory volume in one second (FEV1) and forced vital capacity (FVC) in a random sample of 1555 residents of Western New York, USA...

..We sought to assess the feasibility of self-reported periodontal disease measures using dental history questions combined with demographic and medical history to predict periodontal disease...

..e. drinking intensity and frequency, frequency of intoxication, drinking outside of meals, and beverage type) and subjective health was examined in a random sample of 3586 women and men...

..92, P for trend = 0.05), chance cannot be ruled out as an explanation. We found no evidence of risk related to lifetime alcohol consumption nor evidence that alcohol dehydrogenase genotype modifies risk related to alcohol and lung cancer...

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..Results of studies of non-steroidal anti-inflammatory drugs (NSAIDs) and breast cancer have been inconsistent. Timing of exposure and analysis of individual NSAIDs should be considered...

..We investigated these associations in a relatively large study while evaluating potential confounding factors and effect modification by subgingival calculus and age...

..51; 95% CI, 1.01-2.32). Hypermethylation of RAR-beta(2) gene was inversely associated with histological and nuclear grade of breast cancer...

..The aim of the study is to examine the association between alcohol volume and various drinking patterns and non-fatal myocardial infarction (MI) in women aged 35-69 years...

..This report describes the study design, baseline characteristics and visit completion rate for the BioCycle study...

..To examine whether sleep duration was associated with incident-impaired fasting glucose (IFG) over 6 years of follow-up in the Western New York Health Study...

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..We conducted a nested case-control investigation to examine whether elevated baseline concentrations of cystatin C predicted progression from normoglycemia to pre-diabetes over 6 years of follow-up from the Western New York Health Study...

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..This study focused on geographic clustering of breast cancer based on residence in early life and identified spatio-temporal clustering of cases and controls...

..Emerging data suggest a role for the vitamin D receptor (VDR) in lipogenesis and adipocyte differentiation...

..44-0.98). No association was observed between lignan intakes and postmenopausal breast cancer. Our results suggest that dietary lignans may be important in the etiology of breast cancer, particularly among premenopausal women...

..These findings indicate no overall effect of selenium supplementation on the primary prevention of cardiovascular disease in this population...

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..Evidence supporting an association between osteoporosis and loss of alveolar crestal bone is limited. This study investigated that association in a large cohort of postmenopausal women...

..These results indicate that chronic alteration of glucose metabolism is related to breast cancer development...

..These results support the hypothesis that drinking pattern affects the distribution of body fat, an important CHD risk factor...

..This pilot study was undertaken to establish a methodology and descriptive results for a larger police study...

..Additionally, social network disruptions following 1983 to 1984 evacuation were associated with greater distress (not all measures). These findings suggest that psychological distress from natural disasters may be very long lasting...

..However, there is little evidence regarding the association of anemia with HRQL in patients with chronic obstructive pulmonary disease (COPD)...

..Larger studies are required to determine the role of PON1 and there is a need for standardized PON1 assays between laboratories...

..These results provide important initial information on the variability of biomarkers of oxidative stress, antioxidant defence and micronutrients across the menstrual cycle...

..The present study assesses if the observed association between periodontal disease and incident myocardial infarction (MI) depends on the measurements and/or criteria used to define periodontal disease...

..These results suggest a possible role of inflammation in insulin resistance and glucose intolerance...

..The action research model proved to be beneficial in helping faculty from diverse health disciplines build consensus as they identified common professional and interprofessional learning needs...

..To analyze the relationship between average volume of alcohol consumption and all-cause mortality in African Americans...

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..Their findings support the hypothesis that carotenoids, vitamin C, and vitamin E may play a role in respiratory health and that carotenoids other than beta-carotene may be involved...

..The aim of this study was to investigate the role of central adiposity in the association between overweight, high BP, and insulin resistance...

..Few studies have evaluated this relationship in women. In addition, although menopausal hormone therapy (HT) may alter markers of fibrinolytic function, the relevance of this effect for coronary risk assessment has not been studied...

..In this report, we provide the final results with regard to estrogen plus progestin and CHD from the Women's Health Initiative (WHI)...

..Broad summary measures that reflect alcohol's possible effects on morbidity, mortality, and disability may be more useful than measures of any one outcome alone...

..This study compared CVD risk factors and rates between postmenopausal women who had and had not undergone hysterectomy, with or without oophorectomy...

..CONCLUSION: These results suggest that abdominal adiposity is a better predictor of pulmonary function than weight or BMI, and investigators should consider it when investigating the determinants of pulmonary function...

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..0002) and to ABO in women only (p for trend<0.0001). It is concluded that lifetime drinking patterns are significantly related to the prevalence of the metabolic syndrome...

..Prevalence of the MetS and its individual components, including obesity, high triglycerides, low high-density lipoprotein cholesterol, elevated blood pressure, and high fasting glucose, were the main outcomes...

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..This article describes the occurrence of adverse events during the pilot study...

..Multiple epidemiologic studies and some trials have linked diet with cardiovascular disease (CVD) prevention, but long-term intervention data are needed...

..The purpose of this study was to analyze the interrelationship among oxidation, myocardial infarction (MI), and type 2 diabetes in a population-based case-control study of MI...

..Our aim was to determine whether a history of having been breastfed as an infant is a determinant of adult pulmonary function...

..Aim To evaluate whether enhanced Na-Li CT activity is a predictor of type 2 diabetes...

..To assess coronary heart disease (CHD) risk within levels of the joint distribution of non-HDL and LDL cholesterol among individuals with and without diabetes...

..To examine the relationship between baseline hypertension, blood pressure, and the development of cognitive decline in participants in the Women's Health Initiative Memory Study (WHIMS)...