Maria Tretiakova

Summary

Affiliation: University of Chicago
Country: USA

Publications

  1. doi request reprint Microvessel density is not increased in prostate cancer: digital imaging of routine sections and tissue microarrays
    Maria Tretiakova
    Department of Pathology, University of Chicago, Chicago, IL 60546, USA
    Hum Pathol 44:495-502. 2013
  2. doi request reprint Laser microdissection for gene expression study of hepatocellular carcinomas arising in cirrhotic and non-cirrhotic livers
    Maria Tretiakova
    Department of Pathology, University of Chicago, Chicago, IL, USA
    Methods Mol Biol 755:233-44. 2011
  3. doi request reprint A model of gene-environment interaction reveals altered mammary gland gene expression and increased tumor growth following social isolation
    J Bradley Williams
    The University of Chicago, 5841 South Maryland Avenue, MC 2115, Chicago, IL 60637, USA
    Cancer Prev Res (Phila) 2:850-61. 2009
  4. doi request reprint Differential expression of RON in small and non-small cell lung cancers
    Rajani Kanteti
    Section of Hematology Oncology, Department of Medicine, University of Chicago, Chicago, IL 60637, USA
    Genes Chromosomes Cancer 51:841-51. 2012
  5. doi request reprint Epidermal growth factor receptor controls flat dysplastic aberrant crypt foci development and colon cancer progression in the rat azoxymethane model
    Urszula Dougherty
    Department of Medicine, University of Chicago Hospitals and Clinics, Chicago, IL 60637, USA
    Clin Cancer Res 14:2253-62. 2008
  6. pmc Protein kinase C beta in malignant pleural mesothelioma
    Leonardo Faoro
    Section of Hematology Oncology, Department of Medicine, University of Chicago Pritzker School of Medicine, Chicago, Illinois 60637 1470, USA
    Anticancer Drugs 19:841-8. 2008
  7. pmc Epidermal growth factor receptor signaling is required for microadenoma formation in the mouse azoxymethane model of colonic carcinogenesis
    Alessandro Fichera
    Department of Medicine, University of Chicago, Chicago, Illinois 60637, USA
    Cancer Res 67:827-35. 2007
  8. ncbi request reprint P504S immunostaining boosts diagnostic resolution of "suspicious" foci in prostatic needle biopsy specimens
    Zhong Jiang
    Department of Pathology, University of Massachusetts Medical School, Worcester, USA
    Am J Clin Pathol 121:99-107. 2004
  9. ncbi request reprint Epidermal growth factor receptor signaling is up-regulated in human colonic aberrant crypt foci
    Greg Cohen
    Department of Medicine, University of Chicago, Illinois, USA
    Cancer Res 66:5656-64. 2006
  10. doi request reprint Diffusion-weighted and dynamic contrast-enhanced MRI of prostate cancer: correlation of quantitative MR parameters with Gleason score and tumor angiogenesis
    Aytekin Oto
    Department of Radiology, University of Chicago, IL 60637, USA
    AJR Am J Roentgenol 197:1382-90. 2011

Detail Information

Publications57

  1. doi request reprint Microvessel density is not increased in prostate cancer: digital imaging of routine sections and tissue microarrays
    Maria Tretiakova
    Department of Pathology, University of Chicago, Chicago, IL 60546, USA
    Hum Pathol 44:495-502. 2013
    ..Similar microvessel density of low- and high-grade tumors indicate that microvessel density is neither an important nor reliable prognostic marker for prostate cancer...
  2. doi request reprint Laser microdissection for gene expression study of hepatocellular carcinomas arising in cirrhotic and non-cirrhotic livers
    Maria Tretiakova
    Department of Pathology, University of Chicago, Chicago, IL, USA
    Methods Mol Biol 755:233-44. 2011
    ..0 (MAS 5.0). Results were displayed using Genespring, dChip, SAM, and GenMapp/MAPP Finder software. Validation studies on selected genes and proteins were performed utilizing RT-PCR and immunohistologic techniques...
  3. doi request reprint A model of gene-environment interaction reveals altered mammary gland gene expression and increased tumor growth following social isolation
    J Bradley Williams
    The University of Chicago, 5841 South Maryland Avenue, MC 2115, Chicago, IL 60637, USA
    Cancer Prev Res (Phila) 2:850-61. 2009
    ..g., fatty acid synthesis) for preventive intervention in breast cancer...
  4. doi request reprint Differential expression of RON in small and non-small cell lung cancers
    Rajani Kanteti
    Section of Hematology Oncology, Department of Medicine, University of Chicago, Chicago, IL 60637, USA
    Genes Chromosomes Cancer 51:841-51. 2012
    ..RON was expressed on the cell surface in NSCLC cell lines. Finally, knock down of RON expression resulted in a significant loss in viability as well as motility in lung cancer cells suggesting that RON is a potential therapeutic target...
  5. doi request reprint Epidermal growth factor receptor controls flat dysplastic aberrant crypt foci development and colon cancer progression in the rat azoxymethane model
    Urszula Dougherty
    Department of Medicine, University of Chicago Hospitals and Clinics, Chicago, IL 60637, USA
    Clin Cancer Res 14:2253-62. 2008
    ..Recent studies indicate that flat dysplastic ACF with increased beta-catenin are tumor precursors in this model. We asked, therefore, if EGFR signals are required for flat dysplastic ACF development and cancer progression...
  6. pmc Protein kinase C beta in malignant pleural mesothelioma
    Leonardo Faoro
    Section of Hematology Oncology, Department of Medicine, University of Chicago Pritzker School of Medicine, Chicago, Illinois 60637 1470, USA
    Anticancer Drugs 19:841-8. 2008
    ..Enzastaurin has preclinical activity against MPM, and exhibited synergism with cisplatin. PKCbeta inhibition in MPM might be able to reduce the invasiveness of MPM by affecting cytoskeletal function...
  7. pmc Epidermal growth factor receptor signaling is required for microadenoma formation in the mouse azoxymethane model of colonic carcinogenesis
    Alessandro Fichera
    Department of Medicine, University of Chicago, Chicago, Illinois 60637, USA
    Cancer Res 67:827-35. 2007
    ..Our findings suggest, moreover, that inhibitors of EGFR might be useful in chemopreventive strategies in individuals at increased risk for colonic malignancies...
  8. ncbi request reprint P504S immunostaining boosts diagnostic resolution of "suspicious" foci in prostatic needle biopsy specimens
    Zhong Jiang
    Department of Pathology, University of Massachusetts Medical School, Worcester, USA
    Am J Clin Pathol 121:99-107. 2004
    ..Thus, the consensus diagnosis rate improved from poor to good after supplementing 34 beta E12 immunostaining with P504S...
  9. ncbi request reprint Epidermal growth factor receptor signaling is up-regulated in human colonic aberrant crypt foci
    Greg Cohen
    Department of Medicine, University of Chicago, Illinois, USA
    Cancer Res 66:5656-64. 2006
    ..In summary, we have shown that ACF with up-regulated PCNA possess increased EGFR signaling components that likely contribute to the enhanced proliferative state of dysplastic-appearing ACF...
  10. doi request reprint Diffusion-weighted and dynamic contrast-enhanced MRI of prostate cancer: correlation of quantitative MR parameters with Gleason score and tumor angiogenesis
    Aytekin Oto
    Department of Radiology, University of Chicago, IL 60637, USA
    AJR Am J Roentgenol 197:1382-90. 2011
    ..The objective of our study was to investigate whether quantitative parameters derived from diffusion-weighted imaging (DWI) and dynamic contrast-enhanced MRI (DCE-MRI) correlate with Gleason score and angiogenesis of prostate cancer...
  11. doi request reprint Technical report: laser microdissection of cochlear structures from celloidin embedded human temporal bone tissues and detection of the mitochondrial DNA common deletion using real time PCR
    Adam Markaryan
    Section of Otolaryngology Head and Neck Surgery, Department of Surgery, University of Chicago, 5841 S Maryland Avenue, MC 1035, Chicago, IL 60637, United States
    Hear Res 244:1-6. 2008
    ..To our knowledge, this approach to analyzing archival human temporal bone tissues has not been previously reported...
  12. pmc RON (MST1R) is a novel prognostic marker and therapeutic target for gastroesophageal adenocarcinoma
    Daniel V T Catenacci
    University of Chicago, USA
    Cancer Biol Ther 12:9-46. 2011
    ..These preclinical studies define RON as an important novel prognostic marker and therapeutic target for gastroesophageal cancer warranting further investigation...
  13. doi request reprint Epithelial-to-mesenchymal transition in metaplastic breast carcinomas with chondroid differentiation: expression of the E-cadherin repressor Snail
    Katja Gwin
    Department of Pathology, University of Chicago, The University of Chicago Medical Center, 5841 South Maryland Avenue, Chicago, IL 60637 1470, USA
    Appl Immunohistochem Mol Morphol 18:526-31. 2010
    ..E-cadherin expression was inversely correlated with active nuclear Snail expression. Our results suggest that EMT is induced in MBCD and may contribute to their frequent hematogenous metastasis...
  14. pmc Peroxisome proliferator-activated receptor-delta induces cell proliferation by a cyclin E1-dependent mechanism and is up-regulated in thyroid tumors
    Lingchun Zeng
    Department of Pathology, University of Chicago School of Medicine, University of Chicago Cancer Research Center, Chicago, Illinois, USA
    Cancer Res 68:6578-86. 2008
    ..The data argue for systematic investigation of PPARdelta antagonists as antineoplastic agents and implicate altered PPARdelta-cyclin E1 signaling in thyroid and other carcinomas...
  15. pmc Arginase-1: a new immunohistochemical marker of hepatocytes and hepatocellular neoplasms
    Benjamin C Yan
    Department of Pathology, University of Chicago Medical Center, Chicago, IL 60637, USA
    Am J Surg Pathol 34:1147-54. 2010
    ..Arg-1 represents a sensitive and specific marker of benign and malignant hepatocytes that may ultimately prove to be a useful diagnostic tool in routine surgical pathology practice...
  16. pmc PAX5 is expressed in small-cell lung cancer and positively regulates c-Met transcription
    Rajani Kanteti
    Department of Hematology Oncology, University of Chicago Medical Center, Chicago, IL 60637, USA
    Lab Invest 89:301-14. 2009
    ..Therefore, we propose that PAX5 could be an important regulator of c-Met transcription and a potential target for therapy in SCLC...
  17. ncbi request reprint Analysis of alpha-methylacyl-CoA racemase (P504S) expression in high-grade prostatic intraepithelial neoplasia
    Chin Lee Wu
    Department of Pathology, Massachusetts General Hospital, Harvard Medical School, Boston, USA
    Hum Pathol 35:1008-13. 2004
    ..This study provides additional evidence to link high-grade PIN as a precursor lesion to prostatic adenocarcinoma...
  18. pmc Reprogramming of CTLs into natural killer-like cells in celiac disease
    Bertrand Meresse
    Department of Pathology, University of Chicago, Chicago, IL 60637, USA
    J Exp Med 203:1343-55. 2006
    ....
  19. pmc Cytosolic PLA2 is required for CTL-mediated immunopathology of celiac disease via NKG2D and IL-15
    Fangming Tang
    Department of Pathology, University of Chicago, Chicago, IL 60637, USA
    J Exp Med 206:707-19. 2009
    ..These results reveal an unrecognized link between NKG2D and tissue inflammation, which may underlie the emerging role of NKG2D in various immunopathological conditions and define new therapeutic targets...
  20. ncbi request reprint Ursodeoxycholic acid inhibits Ras mutations, wild-type Ras activation, and cyclooxygenase-2 expression in colon cancer
    Sharad Khare
    Department of Medicine, University of Chicago, Chicago, Illinois 60637, USA
    Cancer Res 63:3517-23. 2003
    ..In summary, we have shown for the first time that UDCA suppressed the development of tumors with Ras mutations and blocked activation of WT Ras. Furthermore, UDCA inhibited Cox-2 induction by Ras-dependent and -independent mechanisms...
  21. pmc Expression patterns of PAX5, c-Met, and paxillin in neuroendocrine tumors of the lung
    Jie Song
    Department of Pathology, University of Chicago Medical Center, Chicago, IL, USA
    Arch Pathol Lab Med 134:1702-5. 2010
    ..The expression patterns of these functionally related proteins have not, to our knowledge, been systemically studied in neuroendocrine tumors of the lung...
  22. pmc Paxillin expression and amplification in early lung lesions of high-risk patients, lung adenocarcinoma and metastatic disease
    Alexander C MacKinnon
    Department of Pathology, University of Chicago Medical Center, Chicago, Illinois 60637, USA
    J Clin Pathol 64:16-24. 2011
    ..A murine in vivo xenograft model of the most common paxillin mutation (A127T) showed increased cell proliferation and invasive tumour growth, establishing an important role for paxillin in the development of lung cancer...
  23. ncbi request reprint Expression of vitamin D3 receptor in kidney tumors
    Wenhua Liu
    Department of Pathology, The University of Chicago Hospitals, University of Chicago, 5841 S Maryland Avenue, Chicago, IL 60637, USA
    Hum Pathol 37:1268-78. 2006
    ..In addition, the focal and much weaker VDR expression in clear cell RCCs makes VDR valuable in distinguishing clear cell RCC from other types of RCCs...
  24. ncbi request reprint Caveolin and thrombospondin expression during hepatocellular carcinogenesis
    Lisa M Yerian
    Department of Pathology, University of Chicago Hospitals, Chicago, IL 60637, USA
    Am J Surg Pathol 28:357-64. 2004
    ..The results illustrate the critical role of histologic techniques in interpretation of microarray data...
  25. pmc Loss of E-cadherin promotes ovarian cancer metastasis via alpha 5-integrin, which is a therapeutic target
    Kenjiro Sawada
    Department of Obstetrics and Gynecology Section of Gynecologic Oncology, University of Chicago, Chicago, IL 60637, USA
    Cancer Res 68:2329-39. 2008
    ..Targeting this integrin could be a promising therapy for a subset of ovarian cancer patients...
  26. doi request reprint Renal medullary carcinoma: rhabdoid features and the absence of INI1 expression as markers of aggressive behavior
    Jason X Cheng
    Department of Pathology, University of Chicago, Chicago, IL 60637, USA
    Mod Pathol 21:647-52. 2008
    ..However, the absence of INI1 expression is not necessarily predictive of rhabdoid histopathology but remains associated with aggressive behavior in renal medullary carcinoma...
  27. ncbi request reprint MET and phosphorylated MET as potential biomarkers in lung cancer
    Maria Tretiakova
    University of Chicago, Department of Pathology, Chicago, Illinois 60637, USA
    J Environ Pathol Toxicol Oncol 30:341-54. 2011
    ..12- 3.07; and P = .034; HR, 1.70; 95% CI, 1.04-2.78, respectively). In summary, MET, pMET, and HGF are highly expressed in both NSCLC and SCLC. Specific forms of pMET may serve as potential biomarkers in lung cancer...
  28. doi request reprint Evaluation of microvascular density in Barrett's associated neoplasia
    Vani J A Konda
    Center for Endoscopic Research and Therapeutics, Section of Gastroenterology, University of Chicago Medical Center, Chicago, IL, USA
    Mod Pathol 26:125-30. 2013
    ..Furthermore, the differences in the most superficial mucosal layers are consistent with findings of increased vascularity by depth-restricted imaging modalities...
  29. ncbi request reprint Detection of alpha-methylacyl-coenzyme A racemase in postradiation prostatic adenocarcinoma
    Ximing J Yang
    Department of Pathology, University of Chicago Pritzker School of Medicine, Chicago, Illinois, USA
    Urology 62:282-6. 2003
    ..It has been demonstrated that AMACR is overexpressed in the vast majority of prostatic adenocarcinoma cases by cDNA microarray, RNA analysis, Western blotting, and immunohistochemistry...
  30. ncbi request reprint Altered expression of alpha-methylacyl-coenzyme A racemase in prostatic adenocarcinoma following hormone therapy
    Kimiko Suzue
    Department of Pathology, University of Chicago Hospital, Chicago, IL, USA
    Am J Clin Pathol 123:553-61. 2005
    ..Furthermore, AMACR might have a role in the recurrence of prostatic adenocarcinoma after medical therapy...
  31. pmc Analysis of Drosophila segmentation network identifies a JNK pathway factor overexpressed in kidney cancer
    Jiang Liu
    Institute for Genomics and Systems Biology, University of Chicago and Argonne National Laboratory, Chicago, IL 60637, USA
    Science 323:1218-22. 2009
    ..SPOP expression distinguished histological subtypes of RCC and facilitated identification of clear cell RCC as the primary tumor for metastatic lesions...
  32. doi request reprint CREB3L2-PPARgamma fusion mutation identifies a thyroid signaling pathway regulated by intramembrane proteolysis
    Weng Onn Lui
    Department of Pathology, University of Chicago Medical Center, Chicago, Illinois 60637, USA
    Cancer Res 68:7156-64. 2008
    ..Our findings identify a novel CREB3L2-PPARgamma gene fusion mutation in thyroid carcinoma and reveal a thyroid signaling pathway that is regulated by intramembrane proteolysis and disrupted in cancer...
  33. pmc Phase II trial of temsirolimus in patients with metastatic breast cancer
    Gini F Fleming
    The University of Chicago Medical Center, 5841 South Maryland Ave, MC 2115, Chicago, IL 60637, USA
    Breast Cancer Res Treat 136:355-63. 2012
    ..We found no evidence that either absence of immunohistochemical staining for PTEN or mutations in the hotspot domains of PIK3CA in the primary tumor were associated with clinical benefit...
  34. doi request reprint Prostate cancer: differentiation of central gland cancer from benign prostatic hyperplasia by using diffusion-weighted and dynamic contrast-enhanced MR imaging
    Aytekin Oto
    Department of Radiology, University of Chicago, 5841 S Maryland Ave, MC 2026, Chicago, IL 60637, USA
    Radiology 257:715-23. 2010
    ....
  35. doi request reprint The different morphologies of urachal adenocarcinoma do not discriminate genomically by micro-RNA expression profiling
    Mei Lin Z Bissonnette
    Department of Pathology, University of Chicago, Chicago, IL 60637, USA
    Hum Pathol 44:1605-11. 2013
    ..This finding, if further validated in larger studies, may have implications in future clinical therapeutic trials for urachal adenocarcinoma with regard to patient grouping and choice of therapy. ..
  36. ncbi request reprint c-Met is a potentially new therapeutic target for treatment of human melanoma
    Neelu Puri
    Departments of Hematology Oncology and Pathology, University of Chicago Medical Center, Chicago, Illinois 60607, USA
    Clin Cancer Res 13:2246-53. 2007
    ..In this study, we investigated the role of c-Met in melanoma biology using a novel small-molecule tyrosine kinase inhibitor SU11274 and small interfering (si) RNA against the receptor...
  37. doi request reprint Chemokine expression in melanoma metastases associated with CD8+ T-cell recruitment
    Helena Harlin
    Department of Pathology, The University of Chicago, Chicago, Illinois 60637, USA
    Cancer Res 69:3077-85. 2009
    ..Our results suggest that lack of critical chemokines in a subset of melanoma metastases may limit the migration of activated T cells, which in turn could limit the effectiveness of antitumor immunity...
  38. pmc Role of protein kinase C β and vascular endothelial growth factor receptor in malignant pleural mesothelioma: Therapeutic implications and the usefulness of Caenorhabditis elegans model organism
    Sivakumar Loganathan
    Section of Hematology Oncology, University of Chicago, Chicago, IL 60637, USA
    J Carcinog 10:4. 2011
    ..To examine the role of both protein kinase C (PKC)-β and vascular endothelial growth factor receptor (VEGFR)-2 in malignant pleural mesothelioma (MPM) using respective inhibitors, enzastaurin and KRN633...
  39. ncbi request reprint Steroid hormone receptor expression in nasopharyngeal angiofibromas. Consistent expression of estrogen receptor beta
    Anthony G Montag
    Laboratory of Surgical Pathology, University of Chicago, Chicago, IL 60637, USA
    Am J Clin Pathol 125:832-7. 2006
    ..None of the cases displayed staining for ER-a or PR. The findings confirm that nasopharyngeal angiofibromas express ER and suggest that new modulators of ER-ss activity may provide an alternative therapy for these lesions...
  40. pmc cDNA microarray analysis of macroregenerative and dysplastic nodules in end-stage hepatitis C virus-induced cirrhosis
    Robert A Anders
    Department of Pathology, Section of Nephrology, The University of Chicago Medical Center, Chicago, Illinois 60637, USA
    Am J Pathol 162:991-1000. 2003
    ..Microarray expression analysis of dysplastic and macroregenerative liver nodules provide insight into the earliest changes in hepatocellular carcinogenesis...
  41. ncbi request reprint Pathogenesis and significance of collagenous micronodules of the prostate
    Valerie Arangelovich
    Department of Pathology, University of Chicago, Chicago, IL, USA
    Appl Immunohistochem Mol Morphol 11:15-9. 2003
    ..Collagenous micronodules are formed by subepithelial accumulations of fragmented collagen fibers, possibly related to the digestion by collagenase produced by prostatic adenocarcinoma cells...
  42. ncbi request reprint Prognostic significance of E-cadherin protein expression in pathological stage I-III endometrial cancer
    Loren K Mell
    Department of Radiation and Cellular Oncology, University of Chicago, Chicago, Illinois, USA
    Clin Cancer Res 10:5546-53. 2004
    ..Decreased expression of E-cadherin in endometrial cancer cells is associated with adverse prognostic features. This study aimed to evaluate the prognostic significance of decreased E-cadherin expression in patients with endometrial cancer...
  43. ncbi request reprint A molecular classification of papillary renal cell carcinoma
    Ximing J Yang
    Department of Pathology, Feinberg School of Medicine, Northwestern University, Illinois, USA
    Cancer Res 65:5628-37. 2005
    ..We report two molecular subclasses of PRCC, which are biologically and clinically distinct and may be readily distinguished in a clinical setting...
  44. doi request reprint Diagnostic utility of CD10 in benign and malignant extrahepatic bile duct lesions
    Maria Tretiakova
    Department of Pathology, University of Chicago Medical Center, Chicago, IL, USA
    Am J Surg Pathol 36:101-8. 2012
    ....
  45. pmc Wnt/beta-catenin pathway activation is enriched in basal-like breast cancers and predicts poor outcome
    Andrey I Khramtsov
    University of Chicago, Department of Medicine, Chicago, IL 60637, USA
    Am J Pathol 176:2911-20. 2010
    ....
  46. pmc A subgenomic segment of Theiler's murine encephalomyelitis virus RNA causes demyelination
    Gleb Baida
    Department of Neurology, University of Chicago Pritzker School of Medicine, Chicago, IL 60637, USA
    J Virol 82:5879-86. 2008
    ..This Cre/loxP transgenic system allows for spatially and temporally controlled expression of the viral transgene and is valuable for clarifying nonimmune (and immune) mechanisms of demyelination induced by TMEV as well as other viruses...
  47. pmc Claudin-1 and claudin-2 expression is elevated in inflammatory bowel disease and may contribute to early neoplastic transformation
    Christopher R Weber
    Department of Pathology, University of Chicago, Chicago, IL 60637, USA
    Lab Invest 88:1110-20. 2008
    ..We speculate that increased claudin-1 and claudin-2 expression may be involved at early stages of transformation in IBD-associated neoplasia...
  48. ncbi request reprint Ursodeoxycholic acid and F(6)-D(3) inhibit aberrant crypt proliferation in the rat azoxymethane model of colon cancer: roles of cyclin D1 and E-cadherin
    Ramesh K Wali
    Department of Medicine, University of Chicago Hospitals and Clinics, Chicago, Illinois 60637, USA
    Cancer Epidemiol Biomarkers Prev 11:1653-62. 2002
    ..In established tumors, UDCA and F(6)-D(3) also limited inductions of cyclooxygenase-2 and inducible nitric oxide synthase, which together with their effects on cyclin D1 and E-cadherin, contribute to their chemopreventive actions...
  49. ncbi request reprint Coordinated induction by IL15 of a TCR-independent NKG2D signaling pathway converts CTL into lymphokine-activated killer cells in celiac disease
    Bertrand Meresse
    Department of Pathology, University of Chicago, IL 60637, USA
    Immunity 21:357-66. 2004
    ....
  50. ncbi request reprint Estrogen receptor-beta expression in extraabdominal fibromatoses: an analysis of 40 cases
    Andrea T Deyrup
    Department of Pathology, Emory University, Atlanta, Georgia, USA
    Cancer 106:208-13. 2006
    ..Early experiments using ligand-binding assays demonstrated the presence of estrogen receptor (ER) in fibromatoses. These findings were not confirmed by later studies using immunohistochemical analysis...
  51. doi request reprint CD61, CD31, and CD34 improve diagnostic accuracy in gastric antral vascular ectasia and portal hypertensive gastropathy: An immunohistochemical and digital morphometric study
    Maria Westerhoff
    Department of Pathology, University of Chicago Medical Center, Chicago, 60637, USA
    Am J Surg Pathol 34:494-501. 2010
    ..MVD analysis can also assist in their distinction. In PHG, the increased vascularity may be subtle in an inflammatory background; vascular markers may serve as adjunct markers for identifying the aberrant vessels...
  52. ncbi request reprint Expression of alpha-Methylacyl-CoA racemase (P504S) in atypical adenomatous hyperplasia of the prostate
    Ximing J Yang
    Department of Pathology, University of Chicago, Illinois, USA
    Am J Surg Pathol 26:921-5. 2002
    ..Because most cases of AAH are negative for P504S, immunostaining of P504S is also of diagnostic value in distinguishing the majority of AAHs from prostatic adenocarcinoma...
  53. pmc Social isolation dysregulates endocrine and behavioral stress while increasing malignant burden of spontaneous mammary tumors
    Gretchen L Hermes
    Departments of Comparative Human Development, Institute for Mind and Biology, The University of Chicago, Chicago, IL 60637, USA
    Proc Natl Acad Sci U S A 106:22393-8. 2009
    ..Our model provides a framework for studying the interaction of social neglect with genetic risk to identify mechanisms whereby psychosocial stressors increase growth and malignancy of breast cancer...
  54. ncbi request reprint The Forkhead Box m1 transcription factor stimulates the proliferation of tumor cells during development of lung cancer
    Il Man Kim
    Department of Medicine, University of Chicago, Chicago, Illinois 60637, USA
    Cancer Res 66:2153-61. 2006
    ..Foxm1-depleted A549 cells exhibit reduced expression of cell cycle-promoting cyclin A2 and cyclin B1 genes. These data show that Foxm1 stimulates the proliferation of tumor cells during progression of NSCLC...
  55. ncbi request reprint P53 expression in small cell carcinoma of the urinary bladder: biological and prognostic implications
    Xiaoyan Wang
    Department of Pathology, Indiana University, Indianapolis, IN, USA
    Anticancer Res 25:2001-4. 2005
    ..88). Our data indicate that p53 is frequently expressed in small cell carcinoma of the urinary bladder. However, no correlation is found between p53 expression and clinicopathologic parameters, including long-term survival...
  56. doi request reprint Technical report: immunofluorescence and TUNEL staining of celloidin embedded human temporal bone tissues
    Adam Markaryan
    Section of Otolaryngology Head and Neck Surgery, Department of Surgery, University of Chicago, 5841 S Maryland Avenue, MC 1035, Chicago, IL 60637, United States
    Hear Res 241:1-6. 2008
    ..These results demonstrate the utility of developing techniques to evaluate the existing collections of archival temporal bones which remain our greatest source of tissue for investigating the causes of ear diseases...
  57. pmc HiSStology: high spectral and spatial resolution magnetic resonance imaging detection of vasculature validated by histology and micro-computed tomography
    Chad R Haney
    Department of Radiology, University of Chicago, Chicago, IL 60637, USA
    Mol Imaging 10:187-96. 2011
    ..The data demonstrate a strong correlation between tumor vasculature identified using HiSS and two gold standards: histology and microCT angiography...