Amy Trentham-Dietz

....

..To examine the association between breast cancer risk factors and second primary cancers (independent diagnoses occurring at least 12 months after the initial breast cancer diagnosis) among breast cancer survivors...

..03) and participated in fewer hours of sporting activity (P=0.08) than students who had not yet reached menarche. These preliminary data suggest that further investigation of the determinants of menarche is both feasible and warranted...

..Obesity is an established risk factor for endometrial cancer. Less well understood is the role of weight gain and weight change in determining risk...

..9 (95% CI: -6.3, 0.6) on the PCS and MCS scales, respectively. These results suggest that breast cancer survivors experience relative declines in health-related QOL across a broad spectrum of domains, even many years after diagnosis...

..Although the associations with cigarette smoking have been explored extensively for invasive breast cancer, the relation to in situ cancer has not previously been examined in depth...

..These findings indicate that women make substantial changes in their behaviors after a DCIS diagnosis. This cohort will be further monitored to evaluate the association between these behaviors and health outcomes following DCIS...

..3%. These findings suggest that a substantial fraction of postmenopausal breast cancer may be avoided by purposeful changes in lifestyle later in life...

..1 years among women born between 1915 and 1919 to 37.7 years among the 1935-1939 cohort (p = 0.0001). These findings have implications for women's lifetime exposure to circulating endogenous hormones...

..Our findings support the hypothesis that some breast cancer risk factors differ by ER and HER-2/neu tumor marker subtypes...

..Lifetime strenuous occupational activity was not associated with invasive breast cancer risk. These results provide further evidence that, for most women, physical activity may reduce the risk of invasive breast cancer...

..16-2.50). In this study we found no overall association between recent consumption of sport-caught fish and breast cancer, although there may be an increased breast cancer risk for subgroups of women who are young and/or premenopausal...

..16; 95% CI, 1.01-1.32 for ever versus never use). Consistent with invasive breast cancer, these results suggest that oral contraceptive use is at most a minor contributor to BCIS risk...

..Our objective was to evaluate women who were occupationally exposed to electromagnetic fields (EMF) and breast cancer risk...

..No significant associations were observed between colorectal cancer risk and age at menarche or age at menopause. These findings suggest differential roles of reproductive factors in colon and rectal cancer etiology...

..09; 95% CI, 1.07-4.07 for ever use versus nonuse). Estrogen-progestin use, both sequential and continuous, appears to be more strongly associated with risk of breast cancer than use of estrogen alone...

..The possible risk for women exposed to levels of atrazine at or above statutory action levels of >or=3 ppb (OR 1.3, 95% CI 0.3-6.5) could not be ruled out due to small numbers in this category...

..Recent studies have also considered potential health effects associated with exposure to environmental contaminants in breastmilk...

..Although the potential for residual confounding by smoking could not be eliminated, these data suggest that physical activity and WBC count are independent risk factors for lung cancer...

..Late age at first full-term birth and nulliparity are known to increase breast cancer risk. The frequency of these risk factors has increased in recent decades...

..However, very few studies have examined individual-level SES in relation to breast cancer survival or have assessed the contextual role of community-level SES independent of individual-level SES...

..49, 1.54) as compared with never users. Despite its small size and potential misclassification of exposure, this study provides evidence against an association between electric blanket or mattress cover use and endometrial cancer...

..Whether increased cadmium is a causal factor for breast cancer or reflects the effects of treatment or disease remains to be determined...

..03). These results indicate that common variation in the TP53 gene could modify the risk of invasive breast cancer...

..04). Our results indicate no overall association between fertility drug use and mammographic density, but provide evidence that density may be lower in women more recently dispensed a fertility drug...

..In contrast, short duration of sleep (<7 h/night) is not substantially associated with increased risk. Further research in this area is warranted...

..We evaluated students' perception of cancer causation among sixth-grade girls living in Wisconsin...

..1(st) quartile) or ionized (HR = 0.85; 95% CI: 0.53, 1.38; 4(th) vs. 1(st) quartile) serum calcium levels. Additionally, we found no evidence for an association among subgroups defined by menopausal status and body mass index...

..To evaluate the concordance of cancer diagnosis from self- and registry reports...

..Animal studies and protein modeling suggest that the Ile655Val polymorphism located in the transmembrane domain of the HER2 protein might influence breast cancer development by altering the efficiency of homodimerization...

..These results suggest that if an association exists with nitrate-nitrogen exposure from residential drinking water consumption, it may be limited to proximal colon cancer...

..Implications for enhancing complicated grief assessment tools and preventative interventions across the continuum of cancer care are highlighted...

..These findings provide a deeper understanding of the information needs of cancer patients and have implications for dissemination strategies that can minimize disparities in access to cancer information...

..These results are consistent with the hypothesis that a saturation of screening mammography utilization contributed to the overall decline in breast cancer incidence...

..The results of this study should be of interest to those seeking to understand or improve HRQoL among this growing population...

..Since physical activity has been shown to ameliorate age-related functional declines, we evaluated the association between physical activity and function in older, long-term colorectal cancer survivors...

..We explored whether higher levels of acculturation were associated with higher rates of cigarette smoking among pregnant Hispanic women residing in the United States...

..The goal of this project was to develop an iterative geocoding process that would achieve a high match rate in a large population-based health study...

..The minor allele of rs6476643 increases risk, whereas the rs2182317 minor allele decreases risk. Both alleles have a high population frequency and a low penetrance toward breast cancer risk...

..Additional studies are needed to determine effects of higher levels, particularly given patterns of increasing phytoestrogen intake...

..Women in these communities should be targeted for interventions to improve the early detection of breast cancer...

..Instead, cases treat menopausal symptoms with vitamin E and soy products, even though the safety and efficacy of these therapies are unproven. The increased use of soy products in this population has not been previously documented...

....

..We examined whether women living in such communities remained at greater risk of breast cancer after controlling for individual education and other known individual-level risk factors...

..These differences suggest that targeted prevention and detection strategies that go beyond equalizing access to mammography may be needed to eliminate breast cancer disparities...

..This study investigated the relation between the incidence of thyroid cancer and socioeconomic indicators of health care access...

..Although the Driver's Privacy Protection Act has restricted access to data on licensed drivers, these data are still an available resource in many states...

..Guided by an explanatory matrix of family conflict at the end of life, the purpose of this article was to examine the correlates and predictors of family conflict reported by 155 spouses and adult children of persons with lung cancer...

..We sought to evaluate national trends in the prevalence of hormone use and to assess variation by type of formulation and patient characteristics...

..To investigate the risk of endometrial cancer associated with various regimens of postmenopausal hormone therapy...

..Use of nonsteroidal anti-inflammatory drugs (NSAID) has been associated with a decrease in breast cancer risk, but it is unknown if they also reduce mammographic density, a strong intermediate marker of breast cancer risk...

..Due to the high prevalence of past and current hormone use, it is important to investigate whether these preparations are related to breast cancer mortality...

..CONCLUSIONS: Among women age > or = 50 years, breast cancer detection by mammography, self detection, and CBE varied according to tumor histopathology...

..76). These data suggest that both low and high birth weights are associated with higher adult BMI and support the hypothesis that fetal experience may influence adult obesity with potential consequences for risk of several major cancers...

..To evaluate the potential interaction between N-acetyltransferase 2 (NAT2) and smoking in breast cancer incidence...

..Of particular interest is the association between combined hormone therapy and increased risk of lobular carcinoma. This lesion is increasingly common but, nonetheless, comprises fewer than 10% of invasive breast cancers...

..Oral contraceptive use was not clearly associated with ductal carcinoma (OR = 1.2, 95%CI = 0.8-1.9). These results suggest that the association between oral contraceptive use and risk of breast cancer may vary by histologic type...

..Overall, our results are consistent with previous studies and suggest that these early life factors have a modest influence on breast cancer risk in postmenopausal women...

..79). No interaction was detected between STK15 variants and estrogenic risk factors, although the power of these analyses was limited. These results suggest that STK15 may represent a low penetrance type breast cancer susceptibility gene...

..We examined survival in a group of postmenopausal women according to BMI...

..To examine the relationship between anthropometric measures and ovarian cancer by menopausal status...

..We analyzed data from a population-based case-control study to evaluate the association between the use of statins and breast cancer risk...

..Whole-genome amplification may introduce substantial allele amplification bias in gDNA collected using a common protocol in population-based epidemiologic studies...

..Additional studies are required to replicate these findings and to determine whether rs361525 is a causative SNP or is a marker of a causative SNP...

..We performed a retrospective cost-effectiveness analysis comparing actual and alternative screening mammography scenarios...

..30), though results for other subtypes were based on sparse data and results were imprecise. In this study, neither total alcohol consumption as a young adult nor recently was associated with an increase in the risk of ovarian cancer...

....

..9, 95% CI = 1.1-3.3). In sum, addressing the career development needs of future leaders in the field by providing career and mentoring sessions at annual meetings may help individuals in the field and enrich the discipline overall...

..This study provides support for reduced overall mortality and mortality from breast cancer among women who engage in physical activity after breast cancer diagnosis...

..The proposed population-based cohort offers a powerful opportunity to inform women and physicians as they consider the trade-offs currently inherent in BCIS treatment. ..

..An award will be given for the best poster. Journal advertisements, posters and direct mail will be used to publicize the meeting. ..

..The proposed population-based cohort offers a powerful opportunity to inform women and physicians as they consider the trade-offs currently inherent in BCIS treatment. ..

..The long-term goal of this project is to reduce the public health impact of BCIS by quantifying both contextual and personal risk factors for the development of BCIS and the recurrence of breast cancer after a BCIS diagnosis. ..