Research Topics
| Miriam M TreggiariSummaryAffiliation: University of Washington Country: USA Publications
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Detail Information
Publications
Effects of anemia and hypotension on porcine optic nerve blood flow and oxygen deliveryLorri A Lee
Department of Anesthesiology, University of Washington, Seattle, Washington 98104, USA
Anesthesiology 108:864-72. 2008..However, the effects of these conditions on optic nerve (ON) blood flow are unknown and cannot be studied adequately in humans...
Hepatic haemodynamic changes following inhibition of endothelium-derived relaxing and hyperpolarising factors in anaesthetised miniature pigsM Treggiari-Venzi
Department of Anaesthesia, Pharmacology and Surgical Intensive Care, University Hospital of Geneva
Schweiz Med Wochenschr 130:608-16. 2000..Neither basal vascular tone nor acetylcholine-induced vasorelaxation are mediated by the opening of glybenclamide-sensitive K+ channels in the hepatic circulation in pigs...
Effect of intensive care unit organizational model and structure on outcomes in patients with acute lung injuryMiriam M Treggiari
Department of Anesthesiology, Harborview Medical Center, University of Washington School of Medicine, 325 Ninth Avenue, Seattle, WA 98104, USA
Am J Respir Crit Care Med 176:685-90. 2007..Prior studies supported an association between intensive care unit (ICU) organizational model or staffing patterns and outcome in critically ill patients...- Approach to eradication of initial Pseudomonas aeruginosa infection in children with cystic fibrosisMiriam M Treggiari
Department of Anesthesiology, Harborview Medical Center, University of Washington School of Medicine, Seattle, Washington 98104, USA
Pediatr Pulmonol 42:751-6. 2007.... - Occupational asbestos exposure and the incidence of non-Hodgkin lymphoma of the gastrointestinal tract: an ecologic studyMiriam M Treggiari
Department of Epidemiology, School of Public Health and Community Medicine, University of Washington, Seattle, WA 98195, USA
Ann Epidemiol 14:168-71. 2004..To test this hypothesis, we sought to determine whether the geographic pattern of the incidence of GINHL in the US has paralleled that of mesothelioma... - Which H is the most important in triple-H therapy for cerebral vasospasm?Miriam M Treggiari
Department of Anesthesiology and Pain Medicine, Harborview Medical Center, University of Washington, Seattle, Washington 98104, USA
Curr Opin Crit Care 15:83-6. 2009..To summarize the recent literature of the hemodynamic management of subarachnoid hemorrhage and cerebral vasospasm, also designated as 'triple-H' therapy, and discuss each component of this management approach individually... - Atrial and brain natriuretic peptide concentrations and the response to inhaled nitric oxide in patients with acute respiratory distress syndromeMiriam M Treggiari
Department of Anesthesiology and Pain Medicine, University of Washington School of Medicine, Harborview Medical Center, PO Box 359724, Seattle, WA 98104, USA
J Crit Care 25:23-9. 2010..We sought to determine whether the response to iNO, defined as 20% Pao(2)/Fio(2) increase from baseline, depends on the level of cardiac natriuretic peptides... - Early anti-pseudomonal acquisition in young patients with cystic fibrosis: rationale and design of the EPIC clinical trial and observational study'Miriam M Treggiari
Department of Anesthesiology and Pain Medicine, University of Washington School of Medicine, Seattle, WA 98104, USA
Contemp Clin Trials 30:256-68. 2009..Risk factors for and clinical impact of early Pa infection in young CF patients are less well understood... - Systematic review of the prevention of delayed ischemic neurological deficits with hypertension, hypervolemia, and hemodilution therapy following subarachnoid hemorrhageMiriam M Treggiari
Division of Surgical Intensive Care, Department of Anesthesia, Pharmacology, and Surgical Intensive Care, University Hospitals, Geneva, Switzerland
J Neurosurg 98:978-84. 2003..The authors therefore conducted a systematic review to evaluate the efficacy of triple-H prevention in decreasing the rate of clinical vasospasm, DINDs, and death... - Cervical sympathetic block to reverse delayed ischemic neurological deficits after aneurysmal subarachnoid hemorrhageMiriam M Treggiari
Division of Surgical Intensive Care, Department of Anesthesia, Pharmacology, and Surgical Intensive Care, Geneva University Hospital, Geneva, Switzerland
Stroke 34:961-7. 2003..The purpose of the present study was to evaluate the feasibility and safety of a locoregional cervical sympathetic block to improve cerebral perfusion in patients suffering from cerebral vasospasm after aneurysmal subarachnoid hemorrhage... - Randomized trial of light versus deep sedation on mental health after critical illnessMiriam M Treggiari
University of Washington, Seattle, WA, USA
Crit Care Med 37:2527-34. 2009..Symptoms of posttraumatic stress disorder are common in patients after they have undergone prolonged mechanical ventilation and are associated with sedation depth... - Review of medical prevention of vasospasm after aneurysmal subarachnoid hemorrhage: a problem of neurointensive careM M Treggiari-Venzi
Department of Anesthesia, Pharmacology, and Surgical Intensive Care, University Hospital, Geneva, Switzerland
Neurosurgery 48:249-61; discussion 261-2. 2001..In addition, it points out some experimental therapies that may hold promise in future clinical trials to prevent the occurrence of vasospasm... - Role of intracranial pressure values and patterns in predicting outcome in traumatic brain injury: a systematic reviewMiriam M Treggiari
Department of Anesthesiology, Harborview Medical Center, University of Washington School of Medicine, Seattle 98104, USA, and Department of Anesthesiology, Pharmacology, and Intensive Care, Geneva University Hospital, Switzerland
Neurocrit Care 6:104-12. 2007..Our purpose was to systematically review the literature to estimate the association between ICP values and patterns and short- and long-term vital and neurological outcome... - Initial Pseudomonas aeruginosa treatment failure is associated with exacerbations in cystic fibrosisNicole Mayer-Hamblett
Department of Pediatrics, University of Washington, Seattle, Washington Seattle Children s Hospital, Seattle, Washington, USA
Pediatr Pulmonol 47:125-34. 2012..The risk of pulmonary exacerbation following Pseudomonas aeruginosa (Pa) acquisition in children with cystic fibrosis (CF) is unknown... - The association between fluid balance and outcomes after subarachnoid hemorrhageRoss P Martini
Department of Anesthesiology and Pain Medicine, Harborview Medical Center, University of Washington, Washington, USA
Neurocrit Care 17:191-8. 2012..We sought to determine the association between early fluid balance and neurological/vital outcome of patients with subarachnoid hemorrhage... - Intensive insulin therapy and mortality in critically ill patientsMiriam M Treggiari
Department of Anaesthesiology, Box 359724, Harborview Medical Center, University of Washington School of Medicine, 325 Ninth Avenue, Seattle, WA 98104, USA
Crit Care 12:R29. 2008..We aimed to determine the association between IIT and mortality in a mixed population of critically ill patients... - Comparative efficacy and safety of 4 randomized regimens to treat early Pseudomonas aeruginosa infection in children with cystic fibrosisMiriam M Treggiari
Department of Anesthesiology and Pain Medicine, Seattle Children s Hospital, WA 98104, USA
Arch Pediatr Adolesc Med 165:847-56. 2011..To investigate the efficacy and safety of 4 antipseudomonal treatments in children with cystic fibrosis with recently acquired Pseudomonas aeruginosa infection... - Is it now time to promote mixed enteral and parenteral nutrition for the critically ill patient?Claudia Paula Heidegger
Geneva University Hospital, Service of Intensive Care, Rue Micheli du Crest 24, 1211, Geneva 14, Switzerland
Intensive Care Med 33:963-9. 2007.... - Intraoperative adherence to a low tidal volume ventilation strategy in critically ill patients with preexisting acute lung injuryOnuma Chaiwat
Department of Anesthesiology, University of Washington School of Medicine, Seattle, Washington, USA
J Crit Care 26:144-51. 2011..This study investigates adherence of intraoperative LTV and whether patient outcomes were different with or without continued intraoperative LTV ventilation in patients with previously established ALI or ARDS... - Mortality and long-term functional outcome associated with intracranial pressure after traumatic brain injuryShide Badri
Department of Anesthesiology and Pain Medicine, Harborview Anesthesiology Research Center, Harborview Medical Center, University of Washington School of Medicine, Seattle, WA 98104, USA
Intensive Care Med 38:1800-9. 2012..We have examined whether raised ICP is independently associated with mortality, functional status and neuropsychological functioning in adult TBI patients... - The effect of an intensive care unit staffing model on tidal volume in patients with acute lung injuryColin R Cooke
Division of Pulmonary and Critical Care Medicine, University of Washington School of Medicine, Harborview Medical Center, 325 9th Avenue, Box 359762, Seattle, Washington, 98104, USA
Crit Care 12:R134. 2008..We aimed to assess the effect of closed-model intensive care on evidence-based ventilatory practice in patients with acute lung injury (ALI)... - Accuracy of transcranial Doppler ultrasonography and single-photon emission computed tomography in the diagnosis of angiographically demonstrated cerebral vasospasmM Sean Kincaid
Department of Anesthesiology, Harborview Medical Center, Seattle, Washington 98104, USA
J Neurosurg 110:67-72. 2009..The goal of this study was to assess the accuracy of the routine clinical use of transcranial Doppler (TCD) ultrasonography and SPECT in predicting angiographically demonstrated vasospasm... - Air cysts and bronchiectasis prevail in nondependent areas in severe acute respiratory distress syndrome: a computed tomographic study of ventilator-associated changesMiriam M Treggiari
Surgical Intensive Care Division, Department of Anesthesiology, Pharmacology and Surgical Intensive Care, University Hospital, Geneva, Switzerland
Crit Care Med 30:1747-52. 2002..e., nondependent regions). Severity of changes revealed by computed tomographic imaging seems to be associated mainly with the high inspiratory pressures required and the length of mechanical ventilation... - Effect of acute lung injury and acute respiratory distress syndrome on outcome in critically ill trauma patientsMiriam M Treggiari
Department of Medicine, Harborview Medical Center, University of Wshington, Seattle, WA, USA
Crit Care Med 32:327-31. 2004..Nonetheless, ALI/ARDS was associated with increased intensive care unit stay and hospital cost, independent of trauma severity... - Transpulmonary lactate gradient after hypothermic cardiopulmonary bypassKarim Bendjelid
Division of Surgical Intensive Care, Department of Anaesthesiology, Pharmacology and Surgical Intensive Care, Geneva University Hospitals, 1211 Geneva, Switzerland
Intensive Care Med 30:817-21. 2004..Because after cardiopulmonary bypass (CPB) some patients develop ALI, the effect of CPB on pulmonary lactate release was investigated... - A nationwide survey of intensive care unit discharge practicesClaudia Paula Heidegger
Division of Surgical Intensive Care, University Hospital, Rue Micheli du Crest 24, 1211, Geneva 14, Switzerland
Intensive Care Med 31:1676-82. 2005..To describe intensive care unit (ICU) discharge practices, examine factors associated with physicians' discharge decisions, and explore ICU and hospital characteristics and clinical determinants associated with the discharge process... - Hemodynamic management of subarachnoid hemorrhageMiriam M Treggiari
Department of Anesthesiology and Pain Medicine, University of Washington, Box 359724, Seattle, WA, USA
Neurocrit Care 15:329-35. 2011..In the context of sparse data, no incremental risk of aneurysmal rupture has been reported with the induction of hemodynamic augmentation... - Postmenopausal hormone use and skeletal fracture: does the size of the benefit decrease with increasing age?Noel S Weiss
University of Washington, Seattle, Washington 98195, USA
Obstet Gynecol 100:364-8. 2002.... - Prolonged propofol anesthesia is not associated with an increase in blood lactateIrene Rozet
Department of Anesthesiology, University of Washington, VA Puget Sound Health Care System, 1660 South Columbian Way, Seattle, WA 98108 1597, USA
Anesth Analg 109:1105-10. 2009..Lactic acidosis is considered an early sign of propofol infusion syndrome. In this study, we investigated the changes in lactate and pH with propofol versus volatile anesthesia (VA) of long duration... - Effect of increasing norepinephrine dosage on regional blood flow in a porcine model of endotoxin shockMiriam M Treggiari
Surgical Intensive Care Division, Department of Anesthesiology, Pharmacology and Surgical Intensive Care, University Hospital, Geneva, Switzerland
Crit Care Med 30:1334-9. 2002..The administration of norepinephrine to increase mean arterial pressure 20 mm Hg above shock did not increase renal and splanchnic blood flows, despite an enhanced cardiac output... - Risk factors for reperfusion injury after lung transplantationSilvia R Cottini
Division of Surgical Intensive Care, Department of Anesthesiology, Pharmacology and Surgical Intensive Care, University Hospital of Geneva, Geneva, Switzerland
Intensive Care Med 32:557-63. 2006..To assess the influence of recipient's and donor's factors as well as surgical events on the occurrence of reperfusion injury after lung transplantation... - A national survey of airway management training in United States internal medicine-based critical care fellowship programsAaron M Joffe
Department of Anesthesiology and Pain Medicine, Harborview Medical Center, Seattle WA 98195 9724, USA
Respir Care 57:1084-8. 2012..Little is known of airway management training provided during fellowship.Our primary aim was to describe the current state of airway education in internal medicine-based critical care fellowship programs... - Randomized trial of the effect of antipyresis by metamizol, propacetamol or external cooling on metabolism, hemodynamics and inflammatory responseValerio Gozzoli
Surgical Intensive Care Division, University Hospital of Geneva, 1211 Geneva 14, Switzerland
Intensive Care Med 30:401-7. 2004..Propacetamol or external cooling should be preferred, although the latter should be avoided in patients unlikely to tolerate the increased metabolic demand induced by external cooling... - New endotracheal tubes designed to prevent ventilator-associated pneumonia: do they make a difference?Steven Deem
Anesthesiology Department, Harborview Medical Center, University of Washington, Box 359724, 325 Ninth Avenue, Seattle, WA 98104, USA
Respir Care 55:1046-55. 2010..It is critical that future studies of ETTs designed to prevent VAP be adequately powered to demonstrate efficacy on important patient outcomes and safety, in addition to cost-effectiveness...