Jason R Tregellas

Summary

Affiliation: University of Colorado Health Sciences Center
Country: USA

Publications

  1. ncbi request reprint Monitoring eye movements during fMRI tasks with echo planar images
    Jason R Tregellas
    Department of Pharmacology, University of Colorado Health Sciences Center, Denver 80262, USA
    Hum Brain Mapp 17:237-43. 2002
  2. ncbi request reprint Gray matter volume differences and the effects of smoking on gray matter in schizophrenia
    Jason R Tregellas
    Research Service, Denver VA Medical Center, Denver, Colorado, USA
    Schizophr Res 97:242-9. 2007
  3. pmc Increased hemodynamic response in the hippocampus, thalamus and prefrontal cortex during abnormal sensory gating in schizophrenia
    Jason R Tregellas
    VISN19 MIRECC, Denver VA Medical Center, Denver, Colorado, USA
    Schizophr Res 92:262-72. 2007
  4. ncbi request reprint Effect of task difficulty on the functional anatomy of temporal processing
    Jason R Tregellas
    Department of Psychiatry, University of Colorado Health Sciences Center, Campus Box C268 71, 4200 E 9th Avenue, Denver, CO 80262, USA
    Neuroimage 32:307-15. 2006
  5. ncbi request reprint FMRI of response to nicotine during a smooth pursuit eye movement task in schizophrenia
    Jason R Tregellas
    Department of Psychiatry, University of Colorado Health Sciences Center, Denver, CO 80262, USA
    Am J Psychiatry 162:391-3. 2005
  6. ncbi request reprint Neurobiology of smooth pursuit eye movement deficits in schizophrenia: an fMRI study
    Jason R Tregellas
    Department of Pharmacology, University of Colorado Health Sciences Center, Denver 80262, USA
    Am J Psychiatry 161:315-21. 2004
  7. pmc Effects of an alpha 7-nicotinic agonist on default network activity in schizophrenia
    Jason R Tregellas
    Department of Psychiatry, Denver VA Medical Center, VISN19 MIRECC, Colorado, USA
    Biol Psychiatry 69:7-11. 2011
  8. pmc Neural effects of auditory distraction on visual attention in schizophrenia
    Jason Smucny
    Neuroscience Program, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA
    PLoS ONE 8:e60606. 2013
  9. pmc Altered default network activity in obesity
    Jason R Tregellas
    Department of Psychiatry, Denver VA Medical Center and University of Colorado Denver, Aurora, Colorado, USA
    Obesity (Silver Spring) 19:2316-21. 2011
  10. pmc Functional magnetic resonance imaging of effects of a nicotinic agonist in schizophrenia
    Jason R Tregellas
    Department of Psychiatry, Denver VA Medical Center VISN19 MIRECC and University of Colorado Denver, Aurora, CO 80045, USA
    Neuropsychopharmacology 35:938-42. 2010

Research Grants

  1. fMRI of Cholinergic Dysfunction in Schizophrenia
    Jason Tregellas; Fiscal Year: 2003

Detail Information

Publications28

  1. ncbi request reprint Monitoring eye movements during fMRI tasks with echo planar images
    Jason R Tregellas
    Department of Pharmacology, University of Colorado Health Sciences Center, Denver 80262, USA
    Hum Brain Mapp 17:237-43. 2002
    ..We demonstrate that local eye movements will influence whole-head motion correction procedures, resulting in inaccurate movement parameters and potentially lowering the sensitivity to detect activations...
  2. ncbi request reprint Gray matter volume differences and the effects of smoking on gray matter in schizophrenia
    Jason R Tregellas
    Research Service, Denver VA Medical Center, Denver, Colorado, USA
    Schizophr Res 97:242-9. 2007
    ..The present study used voxel-based morphometry (VBM) to examine differences in gray matter in subjects with schizophrenia and evaluate the effects of smoking on this measure...
  3. pmc Increased hemodynamic response in the hippocampus, thalamus and prefrontal cortex during abnormal sensory gating in schizophrenia
    Jason R Tregellas
    VISN19 MIRECC, Denver VA Medical Center, Denver, Colorado, USA
    Schizophr Res 92:262-72. 2007
    ..This study used functional magnetic resonance imaging (fMRI) to investigate the functional neuroanatomy of sensory gating deficits in schizophrenia...
  4. ncbi request reprint Effect of task difficulty on the functional anatomy of temporal processing
    Jason R Tregellas
    Department of Psychiatry, University of Colorado Health Sciences Center, Campus Box C268 71, 4200 E 9th Avenue, Denver, CO 80262, USA
    Neuroimage 32:307-15. 2006
    ....
  5. ncbi request reprint FMRI of response to nicotine during a smooth pursuit eye movement task in schizophrenia
    Jason R Tregellas
    Department of Psychiatry, University of Colorado Health Sciences Center, Denver, CO 80262, USA
    Am J Psychiatry 162:391-3. 2005
    ..This study used functional magnetic resonance imaging (fMRI) to examine changes in brain hemodynamic response associated with nicotine administration during a smooth pursuit eye movement task in subjects with schizophrenia...
  6. ncbi request reprint Neurobiology of smooth pursuit eye movement deficits in schizophrenia: an fMRI study
    Jason R Tregellas
    Department of Pharmacology, University of Colorado Health Sciences Center, Denver 80262, USA
    Am J Psychiatry 161:315-21. 2004
    ..The investigators used functional magnetic resonance imaging (fMRI) to compare brain hemodynamic response during a smooth pursuit eye movement task in patients with schizophrenia and healthy comparison subjects...
  7. pmc Effects of an alpha 7-nicotinic agonist on default network activity in schizophrenia
    Jason R Tregellas
    Department of Psychiatry, Denver VA Medical Center, VISN19 MIRECC, Colorado, USA
    Biol Psychiatry 69:7-11. 2011
    ..This study examined the effects of DMXB-A on default network activity as a biomarker for drug effects on pathologic brain function associated with schizophrenia...
  8. pmc Neural effects of auditory distraction on visual attention in schizophrenia
    Jason Smucny
    Neuroscience Program, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA
    PLoS ONE 8:e60606. 2013
    ..These response differences may predict global functioning in the illness, and may serve as a biomarker for therapeutic development...
  9. pmc Altered default network activity in obesity
    Jason R Tregellas
    Department of Psychiatry, Denver VA Medical Center and University of Colorado Denver, Aurora, Colorado, USA
    Obesity (Silver Spring) 19:2316-21. 2011
    ..Future studies of the network's function and its relationship to other brain networks may improve our understanding of the mechanisms and treatment of obesity...
  10. pmc Functional magnetic resonance imaging of effects of a nicotinic agonist in schizophrenia
    Jason R Tregellas
    Department of Psychiatry, Denver VA Medical Center VISN19 MIRECC and University of Colorado Denver, Aurora, CO 80045, USA
    Neuropsychopharmacology 35:938-42. 2010
    ..Imaging of drug response is useful in planning future clinical tests of this compound and other nicotinic agonists for schizophrenia...
  11. doi request reprint Greater neuronal responses during automatic semantic processing in schizophrenia
    Lisa B Wilson
    Department of Psychiatry, University of Colorado Denver, Aurora 80045, USA
    Neuroreport 24:212-6. 2013
    ..Greater priming-related responses within temporal regions may reflect increased and prolonged automatic spreading activation during semantic processing in schizophrenia...
  12. pmc Medial orbitofrontal cortex gray matter is reduced in abstinent substance-dependent individuals
    Jody Tanabe
    Department of Radiology, University of Denver School of Medicine, Denver, CO, USA
    Biol Psychiatry 65:160-4. 2009
    ..We tested the hypothesis that medial OFC gray matter (GM) volume would be lower in SDI compared with control subjects...
  13. pmc Nicotine increases brain functional network efficiency
    Korey P Wylie
    Department of Psychiatry, University of Colorado Anschutz Medical Campus, Bldg 500, Mail Stop F546, 13001 East 17th Place, Aurora, CO 80045, USA
    Neuroimage 63:73-80. 2012
    ..These changes in network topology may be one mechanism by which cholinergic therapies improve brain function...
  14. ncbi request reprint Effects of nicotine on hippocampal and cingulate activity during smooth pursuit eye movement in schizophrenia
    Jody Tanabe
    Department of Radiology, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
    Biol Psychiatry 59:754-61. 2006
    ..The purpose of this work was to determine if nicotine differentially affects brain activity in schizophrenic and control subjects during pursuit eye tracking...
  15. pmc Nicotine effects on default mode network during resting state
    Jody Tanabe
    Department of Radiology, University of Colorado Denver School of Medicine, Denver, CO, USA
    Psychopharmacology (Berl) 216:287-95. 2011
    ..It is unknown if these pharmacological effects also occur in the absence of effortful processing...
  16. doi request reprint The effect of distracting noise on the neuronal mechanisms of attention in schizophrenia
    Jason R Tregellas
    Research Service, Denver VA Medical Center, Denver, CO, United States
    Schizophr Res 142:230-6. 2012
    ..The purpose of this study was to determine if the neuronal response to distracting noise is related to mechanisms of altered attention observed in the illness...
  17. doi request reprint Phonological processing in first-degree relatives of individuals with autism: an fMRI study
    Lisa B Wilson
    Department of Psychiatry, University of Colorado Denver, Aurora, CO 80045, USA
    Hum Brain Mapp 34:1447-63. 2013
    ..Furthermore, interpretation of our fMRI results is limited by the fact that the parent group failed to exhibit behavioral evidence of phonological impairments...
  18. pmc Regional gray matter volumetric changes in autism associated with social and repetitive behavior symptoms
    Donald C Rojas
    Department of Psychiatry, University of Colorado Health Sciences Center, Denver, CO, 80220, USA
    BMC Psychiatry 6:56. 2006
    ..We attempted to replicate these whole brain studies and to correlate regional volume changes with several autism symptom measures...
  19. pmc Sensory gating and alpha-7 nicotinic receptor gene allelic variants in schizoaffective disorder, bipolar type
    Laura F Martin
    Department of Psychiatry, Denver Veterans Affairs Medical Center, Denver, Colorado 80262, USA
    Am J Med Genet B Neuropsychiatr Genet 144:611-4. 2007
    ..The purpose of this study was to determine if CHRNA7 promoter allelic variants are also associated with abnormal P50 ratios in persons with schizoaffective disorder, bipolar type...
  20. pmc A voxel-based morphometry comparison of regional gray matter between fragile X syndrome and autism
    Lisa B Wilson
    Department of Psychiatry, University of Colorado at Denver, Denver, CO, 80045, USA
    Psychiatry Res 174:138-45. 2009
    ..Cerebellar deficits suggest atypical development of the cerebellum contributing to the phenotype of both disorders, but further imply that unique cerebellar regions contribute to the phenotype of each disorder...
  21. ncbi request reprint Reducing susceptibility artifacts in fMRI using volume-selective z-shim compensation
    Yiping P Du
    Department of Psychiatry, University of Colorado at Denver and Health Sciences Center, Aurora, Colorado 80010 7155, USA
    Magn Reson Med 57:396-404. 2007
    ..The results of an fMRI study (N=6) demonstrate the feasibility of detecting the OFC activation with z-shim in whole-brain fMRI studies at a temporal resolution of 2 s...
  22. pmc Implicit phonological priming during visual word recognition
    Lisa B Wilson
    University of Colorado Denver, Department of Psychiatry, Aurora, CO 80045, USA
    Neuroimage 55:724-31. 2011
    ....
  23. pmc Early sensory processing deficits predict sensitivity to distraction in schizophrenia
    Jason Smucny
    Department of Psychiatry, University of Colorado Anschutz Medical Campus, Aurora, CO 80045, USA
    Schizophr Res 147:196-200. 2013
    ..The observed relationship between noise effects on reaction time and P50 auditory gating supports the hypothesis that early inhibitory processing deficits may contribute to susceptibility to distraction in the illness...
  24. pmc Anorexia nervosa and obesity are associated with opposite brain reward response
    Guido K W Frank
    Department of Psychiatry, University of Colorado, Anschutz Medical Campus, Aurora, CO, USA
    Neuropsychopharmacology 37:2031-46. 2012
    ..The mechanism for this association is uncertain, but these brain reward response patterns could be biomarkers for the respective weight state...
  25. ncbi request reprint A voxel-based morphometry study of gray matter in parents of children with autism
    Eric Peterson
    Department of Psychiatry, University of Colorado Health Sciences Center, Denver, Colorado 80262, USA
    Neuroreport 17:1289-92. 2006
    ..This investigation constitutes the first whole-brain study of regional brain volume in the parents of autistic children, and suggests that a number of structural changes observed in autism may be familial...
  26. ncbi request reprint Effects of overfeeding on the neuronal response to visual food cues
    Marc Andre Cornier
    Division of Endocrinology, Metabolism, and Diabetes, Department of Medicine, University of Colorado at Denver, Health Sciences Center, Denver, CO 80045, USA
    Am J Clin Nutr 86:965-71. 2007
    ..Environmental visual cues are one of the first and primary inputs signaling the potential availability of food...
  27. doi request reprint Effects of exercise on resting-state default mode and salience network activity in overweight/obese adults
    Kristina L McFadden
    aDepartment of Psychiatry Divisions of bEndocrinology, Metabolism and Diabetes cGeriatric Medicine, Department of Medicine dAnschutz Health and Wellness Center, University of Colorado Anschutz Medical Campus, Aurora eResearch Service, VA Medical Center, Denver, Colorado, USA
    Neuroreport 24:866-71. 2013
    ..Given previous reports of DMN overactivity in overweight/obese individuals, the present findings may indicate an exercise-related 'normalization' of network function. ..
  28. doi request reprint Brain structure predicts risk for obesity
    Jason Smucny
    Neuroscience Program, University of Colorado Anschutz Medical Campus, Aurora, CO, USA
    Appetite 59:859-65. 2012
    ....

Research Grants1

  1. fMRI of Cholinergic Dysfunction in Schizophrenia
    Jason Tregellas; Fiscal Year: 2003
    ..abstract_text> ..