Research Topics
Genomes and GenesSpecies | Gregory J TranahSummaryAffiliation: University of California Country: USA Publications
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Publications
Domestic and farm-animal exposures and risk of non-Hodgkin's lymphoma in a population-based study in the San Francisco Bay AreaGregory J Tranah
California Pacific Medical Center Research Institute, San Francisco Coordinating Center, University of California San Francisco, San Francisco, CA 94107 1728, USA
Cancer Epidemiol Biomarkers Prev 17:2382-7. 2008..To assess the association between animal exposures and non-Hodgkin's lymphoma (NHL)...
Circadian activity rhythms and mortality: the study of osteoporotic fracturesGregory J Tranah
California Pacific Medical Center Research Institute, San Francisco Coordinating Center, UCSF, 185 Berry Street, Lobby 4, Suite 5700, San Francisco, CA 94107, USA
J Am Geriatr Soc 58:282-91. 2010..To determine whether circadian activity rhythms are associated with mortality in community-dwelling older women...
Solvent exposure and non-Hodgkin lymphoma: no risk in a population-based study in the San Francisco Bay AreaGregory J Tranah
California Pacific Medical Center Research Institute, University of California San Francisco, San Francisco, California 94107 1728, USA
Cancer Epidemiol Biomarkers Prev 18:3130-2. 2009..Odds ratios and 95% confidence intervals were adjusted for potential confounders. Our results have provided no support for an association between NHL and occupational exposure to solvents...
Genetic variation in candidate osteoporosis genes, bone mineral density, and fracture risk: the study of osteoporotic fracturesGregory J Tranah
CPMC Research Institute, San Francisco, CA 94120, USA
Calcif Tissue Int 83:155-66. 2008..In conclusion, polymorphisms in several candidate genes were associated with hip, vertebral, and nonhip/nonvertebral fractures but not with total hip BMD in this large population based cohort study...
Cigarette, cigar and pipe smoking, passive smoke exposure, and risk of pancreatic cancer: a population-based study in the San Francisco Bay AreaGregory J Tranah
California Pacific Medical Center Research Institute, 94107, USA
BMC Cancer 11:138. 2011..To examine the influence of cigarette, cigar and pipe smoking, cessation of cigarette smoking and passive smoke exposure on the risk of pancreatic cancer...
O6-methylguanine-DNA methyltransferase Leu84Phe and Ile143Val polymorphisms and risk of colorectal cancer in the Nurses' Health Study and Physicians' Health Study (United States)Gregory J Tranah
Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
Cancer Causes Control 17:721-31. 2006..Two non-synonymous MGMT coding region variants, Leu84Phe and Ile143Val, lie in close proximity to the reactive 145Cys residue and to a conserved estrogen receptor interacting helix...
Epoxide hydrolase and CYP2C9 polymorphisms, cigarette smoking, and risk of colorectal carcinoma in the Nurses' Health Study and the Physicians' Health StudyGregory J Tranah
Department of Epidemiology, Harvard School of Public Health, Boston, Massachusetts, USA
Mol Carcinog 44:21-30. 2005..Our results indicate that individuals exposed to tobacco carcinogens were at increased risk of colorectal cancer and that overall risk is related to mEH and CYP2C9 genotype, although the results were not consistent between men and women...
Hemochromatosis gene mutations, body iron stores, dietary iron, and risk of colorectal adenoma in womenAndrew T Chan
Gastrointestinal Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA
J Natl Cancer Inst 97:917-26. 2005..We assessed dietary iron intake and genetic and biochemical markers of iron status in a prospective, nested case-control study of women enrolled in the Nurses' Health Study...
Mitochondrial DNA sequence variation is associated with free-living activity energy expenditure in the elderlyGregory J Tranah
California Pacific Medical Center Research Institute, San Francisco, San Francisco, CA, 94107, USA
Biochim Biophys Acta 1817:1691-700. 2012....
XRCC2 and XRCC3 polymorphisms are not associated with risk of colorectal adenomaGregory J Tranah
Department of Epidemiology, and Harvard Center for Cancer Prevention, Harvard School of Public Health, Boston, MA, USA
Cancer Epidemiol Biomarkers Prev 13:1090-1. 2004
Mitochondrial DNA sequence variation associated with dementia and cognitive function in the elderlyGregory J Tranah
California Pacific Medical Center Research Institute, San Francisco, CA, USA
J Alzheimers Dis 32:357-72. 2012....
Circadian activity rhythms and risk of incident dementia and mild cognitive impairment in older womenGregory J Tranah
California Pacific Medical Center Research Institute, San Francisco, CA 94107 1728, USA
Ann Neurol 70:722-32. 2011..We determined whether circadian activity rhythms measured in community-dwelling older women are prospectively associated with incident dementia or mild cognitive impairment (MCI)...
Postmenopausal hormones and sleep quality in the elderly: a population based studyGregory J Tranah
CPMC Research Institute, San Francisco, CA, USA
BMC Womens Health 10:15. 2010..Using data from the multicenter Study of Osteoporotic Fractures (SOF), we tested the relationship between HT and sleep-wake estimated from actigraphy...
Genetic variants in the UGT1A6 enzyme, aspirin use, and the risk of colorectal adenomaAndrew T Chan
Gastrointestinal Unit, Massachusetts General Hospital and Harvard Medical School, GRJ 722, Boston, MA 02114, USA
J Natl Cancer Inst 97:457-60. 2005....
Hip pain while using lower extremity joints and sleep disturbances in elderly white women: results from a cross-sectional analysisNeeta Parimi
San Francisco Coordinating Center, California Pacific Medical Center Research Institute, 185 Berry Street, Lobby 5, Suite 5700, San Francisco, CA 94107 1762, USA
Arthritis Care Res (Hoboken) 64:1070-8. 2012..To evaluate sleep quality in women with hip pain due to daily activities involving the lower extremity joints...
Epoxide hydrolase polymorphisms, cigarette smoking and risk of colorectal adenoma in the Nurses' Health Study and the Health Professionals Follow-up StudyGregory J Tranah
Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
Carcinogenesis 25:1211-8. 2004....
p53 Arg72Pro polymorphism and risk of colorectal adenoma and cancerAnita Koushik
Department of Nutrition, Harvard School of Public Health, Boston, MA 02115, USA
Int J Cancer 119:1863-8. 2006..09, 95% CI = 1.28-3.40) but not proximal colon or rectal cancers. Our results suggest that Arg72Pro may play a role in the early stages of colorectal neoplasia and possibly in progression to invasive disease, depending on site and sex...
APC Asp1822Val and Gly2502Ser polymorphisms and risk of colorectal cancer and adenomaGregory J Tranah
Department of Epidemiology, Harvard School of Public Health, 677 Huntington Avenue, Boston, MA 02115, USA
Cancer Epidemiol Biomarkers Prev 14:863-70. 2005..No gene-environment interactions were observed with these risk factors or with other dietary risk factors previously hypothesized to interact with the APC Asp1822Val polymorphism...
Common genetic variants in ARNTL and NPAS2 and at chromosome 12p13 are associated with objectively measured sleep traits in the elderlyDaniel S Evans
California Pacific Medical Center Research Institute, San Francisco, CA 94107 1728, USA
Sleep 36:431-46. 2013..To determine the association between common genetic variation in the clock gene pathway and objectively measured acti-graphic sleep and activity rhythm traits...
MGMT germline polymorphism is associated with somatic MGMT promoter methylation and gene silencing in colorectal cancerShuji Ogino
Department of Medical Oncology, Dana Farber Cancer Institute, Boston, MA 02115, USA
Carcinogenesis 28:1985-90. 2007..56C>T) of the MGMT promoter and promoter methylation/silencing of MGMT in colorectal cancer. Our data provide compelling evidence for common susceptibility for MGMT promoter CpG island methylation...
Polymorphisms in O6-methylguanine DNA methyltransferase and breast cancer riskJiali Han
Channing Laboratory, Department of Medicine, Brigham and Women s Hospital, and Harvard Medical School, 181 Longwood Avenue, Boston, MA 02115, USA
Pharmacogenet Genomics 16:469-74. 2006..We also evaluated the potential interactions between the two polymorphisms and estrogen-related risk factors and cigarette smoking on breast cancer risk...
Mitochondrial DNA sequence variation and risk of pancreatic cancerErnest T Lam
Institute for Human Genetics, University of California, San Francisco, California, USA
Cancer Res 72:686-95. 2012..Together, the results of this study provide evidence that aggregated common and rare variants and the accumulation of singleton variants are important contributors to pancreatic cancer risk...
Prospective study of N-acetyltransferase-2 genotypes, meat intake, smoking and risk of colorectal cancerAndrew T Chan
Gastrointestinal Unit, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
Int J Cancer 115:648-52. 2005..The influence of NAT2 genotype on this association supports a role for heterocyclic amines in mediating the effect of red meat on colorectal carcinogenesis...
Multiple displacement amplification prior to single nucleotide polymorphism genotyping in epidemiologic studiesGregory J Tranah
Department of Epidemiology, Harvard School of Public Health, Boston, MA 02115, USA
Biotechnol Lett 25:1031-6. 2003..These results suggest that MDA will provide a sufficiently robust amplification of limiting samples of genomic DNA that can be used for SNP genotyping in large case-control studies of complex diseases...
Mitochondrial DNA variation in human metabolic rate and energy expenditureGregory J Tranah
California Pacific Medical Center Research Institute, San Francisco, CA, 94107, USA
Mitochondrion 11:855-61. 2011..This study links mitochondrial haplogroups with ancestry-associated differences in metabolic rate and energy expenditure...
A prospective study of genetic polymorphisms in the cytochrome P-450 2C9 enzyme and the risk for distal colorectal adenomaAndrew T Chan
Gastrointestinal Unit, Massachusetts General Hospital and Harvard Medical School, Boston 02114, USA
Clin Gastroenterol Hepatol 2:704-12. 2004..Genetic variation in this enzyme may modulate the influence of aspirin and smoking on adenoma risk...
