Steven M Tracy

Summary

Affiliation: University of Nebraska Medical Center
Country: USA

Publications

  1. ncbi request reprint Group B coxsackievirus myocarditis and pancreatitis: connection between viral virulence phenotypes in mice
    S Tracy
    Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha 68198 6495, USA
    J Med Virol 62:70-81. 2000
  2. doi request reprint Enteroviruses and type 1 diabetes
    Steven Tracy
    Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE 68198, USA
    Diabetes Metab Res Rev 27:820-3. 2011
  3. doi request reprint Enteroviruses, type 1 diabetes and hygiene: a complex relationship
    S Tracy
    Department of Pathology and Microbiology, University of Nebraska Medical Center, 986495 Nebraska Medical Center, Omaha, NE 68198 6495, USA
    Rev Med Virol 20:106-16. 2010
  4. ncbi request reprint Group B coxsackievirus virulence
    S Tracy
    Department of Pathology and Microbiology, University of Nebraska, 986495 Nebraska Medical Center, Omaha, NE 68198, USA
    Curr Top Microbiol Immunol 323:49-63. 2008
  5. ncbi request reprint Coxsackievirus infections and NOD mice: relevant models of protection from, and induction of, type 1 diabetes
    Steven Tracy
    Department of Pathology and Microbiology, University of Nebraska Medical Center, 986495 Nebraska Medical Center, Omaha NE 68198, USA
    Ann N Y Acad Sci 1103:143-51. 2007
  6. pmc Toward testing the hypothesis that group B coxsackieviruses (CVB) trigger insulin-dependent diabetes: inoculating nonobese diabetic mice with CVB markedly lowers diabetes incidence
    S Tracy
    Enterovirus Research Laboratory, University of Nebraska Medical Center, Omaha, Nebraska 68198, USA
    J Virol 76:12097-111. 2002
  7. ncbi request reprint Evolution of virulence in picornaviruses
    S Tracy
    Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE 68198 6495, USA
    Curr Top Microbiol Immunol 299:193-209. 2006
  8. ncbi request reprint The stem loop II within the 5' nontranslated region of clinical coxsackievirus B3 genomes determines cardiovirulence phenotype in a murine model
    James J Dunn
    Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, USA
    J Infect Dis 187:1552-61. 2003
  9. ncbi request reprint Characterization of an infectious cDNA copy of the genome of a naturally occurring, avirulent coxsackievirus B3 clinical isolate
    C K Lee
    Enterovirus Research Laboratory, Department of Pathology and Microbiology, University of Nebraska Medical Center, 986495 Nebraska Medical Center, Omaha, NE 68198, USA
    J Gen Virol 86:197-210. 2005
  10. pmc 5'-Terminal deletions occur in coxsackievirus B3 during replication in murine hearts and cardiac myocyte cultures and correlate with encapsidation of negative-strand viral RNA
    K S Kim
    Enterovirus Research Laboratory, Department of Pathology and Microbiology, University of Nebraska Medical Center, 986495 Nebraska Medical Center, Omaha, NE 68198 6495, USA
    J Virol 79:7024-41. 2005

Detail Information

Publications18

  1. ncbi request reprint Group B coxsackievirus myocarditis and pancreatitis: connection between viral virulence phenotypes in mice
    S Tracy
    Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha 68198 6495, USA
    J Med Virol 62:70-81. 2000
    ..The data are consistent with the possibility of an etiologic link between CVB-induced pancreatic and heart disease...
  2. doi request reprint Enteroviruses and type 1 diabetes
    Steven Tracy
    Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE 68198, USA
    Diabetes Metab Res Rev 27:820-3. 2011
    ....
  3. doi request reprint Enteroviruses, type 1 diabetes and hygiene: a complex relationship
    S Tracy
    Department of Pathology and Microbiology, University of Nebraska Medical Center, 986495 Nebraska Medical Center, Omaha, NE 68198 6495, USA
    Rev Med Virol 20:106-16. 2010
    ..Viewing T1D in this perspective suggests that potential preventative options could be developed...
  4. ncbi request reprint Group B coxsackievirus virulence
    S Tracy
    Department of Pathology and Microbiology, University of Nebraska, 986495 Nebraska Medical Center, Omaha, NE 68198, USA
    Curr Top Microbiol Immunol 323:49-63. 2008
    ..It is not known how highly virulent CVB strains may arise but evidence suggests such strains are not the norm...
  5. ncbi request reprint Coxsackievirus infections and NOD mice: relevant models of protection from, and induction of, type 1 diabetes
    Steven Tracy
    Department of Pathology and Microbiology, University of Nebraska Medical Center, 986495 Nebraska Medical Center, Omaha NE 68198, USA
    Ann N Y Acad Sci 1103:143-51. 2007
    ..These models expand much of what is known or suspected regarding the etiologic role of HEVs in human T1D...
  6. pmc Toward testing the hypothesis that group B coxsackieviruses (CVB) trigger insulin-dependent diabetes: inoculating nonobese diabetic mice with CVB markedly lowers diabetes incidence
    S Tracy
    Enterovirus Research Laboratory, University of Nebraska Medical Center, Omaha, Nebraska 68198, USA
    J Virol 76:12097-111. 2002
    ..To the contrary, CVB infections provide significant protection from T1D onset in NOD mice. Possible mechanisms by which this virus-induced protection may occur are discussed...
  7. ncbi request reprint Evolution of virulence in picornaviruses
    S Tracy
    Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, NE 68198 6495, USA
    Curr Top Microbiol Immunol 299:193-209. 2006
    ..Ultimately, the ability of a picornavirus to induce disease depends upon viral genetics and how they are modulated by the host environment...
  8. ncbi request reprint The stem loop II within the 5' nontranslated region of clinical coxsackievirus B3 genomes determines cardiovirulence phenotype in a murine model
    James J Dunn
    Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska, USA
    J Infect Dis 187:1552-61. 2003
    ..The identity of this higher-order RNA structure may be essential for productive infection of cardiac cells...
  9. ncbi request reprint Characterization of an infectious cDNA copy of the genome of a naturally occurring, avirulent coxsackievirus B3 clinical isolate
    C K Lee
    Enterovirus Research Laboratory, Department of Pathology and Microbiology, University of Nebraska Medical Center, 986495 Nebraska Medical Center, Omaha, NE 68198, USA
    J Gen Virol 86:197-210. 2005
    ..This is the first report characterizing a cloned CVB3 genome from an avirulent strain...
  10. pmc 5'-Terminal deletions occur in coxsackievirus B3 during replication in murine hearts and cardiac myocyte cultures and correlate with encapsidation of negative-strand viral RNA
    K S Kim
    Enterovirus Research Laboratory, Department of Pathology and Microbiology, University of Nebraska Medical Center, 986495 Nebraska Medical Center, Omaha, NE 68198 6495, USA
    J Virol 79:7024-41. 2005
    ..These studies describe a naturally occurring genomic alteration to an enteroviral genome associated with long-term viral persistence...
  11. pmc Replication of coxsackievirus B3 in primary cell cultures generates novel viral genome deletions
    K S Kim
    Department of Pathology and Microbiology, University of Nebraska Medical Center, 986495 Nebraska Medical Center, Omaha, NE 68198 6495, USA
    J Virol 82:2033-7. 2008
    ..The cellular environment of contact-inhibited primary cell cultures or the myocardium in vivo is sufficient for the selection of 5' TDs over undeleted genomes...
  12. pmc Coxsackievirus expression of the murine secretory protein interleukin-4 induces increased synthesis of immunoglobulin G1 in mice
    N M Chapman
    Enterovirus Research Laboratory, Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska 68198, USA
    J Virol 74:7952-62. 2000
    ..Comparison of the murine antibody responses to CVB3-PL2-mIL4/46 and the parental CVB3/0 strain demonstrated an increased level of CVB3-binding serum immunoglobulin G1 in mice inoculated with CVB3-PL2-mIL4/46...
  13. pmc A group B coxsackievirus/poliovirus 5' nontranslated region chimera can act as an attenuated vaccine strain in mice
    N M Chapman
    Enterovirus Research Laboratory, Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska 68198 6495, USA
    J Virol 74:4047-56. 2000
    ....
  14. ncbi request reprint Genetics of coxsackievirus B cardiovirulence and inflammatory heart muscle disease
    S Tracy
    Dept of Pathology and Microbiology, University of Nebraska Medical Center, Omaha 68198 6495, USA
    Trends Microbiol 4:175-9. 1996
    ..The relative importance of these sites to expression of the phenotype remains unclear...
  15. pmc Injection of the sciatic nerve with TMEV: a new model for peripheral nerve demyelination
    Kristen M Drescher
    Department of Medical Microbiology and Immunology, Creighton University School of Medicine, 2500 California Plaza, Criss II, Room 424, Omaha, NE 68178, USA
    Virology 359:233-42. 2007
    ..i., hindlimbs were paralyzed. This new model of virus-induced peripheral demyelination may be used to dissect processes involved in protection of the PNS from viral insult and to study the early phases of lesion development...
  16. ncbi request reprint The group B coxsackieviruses and myocarditis
    K S Kim
    Enterovirus Research Laboratory, Department of Pathology and Microbiology, University of Nebraska Medical Center, 986495 Nebraska Medical Center, Omaha, NE 68198-6495, USA
    Rev Med Virol 11:355-68. 2001
    ....
  17. ncbi request reprint Monoclonal antibody against mouse CAR following genetic immunization
    Steven D Carson
    Department of Pathology and Microbiology, University of Nebraska Medical Center, Omaha, Nebraska 68198 6495, USA
    Hybrid Hybridomics 23:19-22. 2004
    ..Since CAR has been shown to form dimers, expression of human CAR in cells that express mouse CAR may have stimulated the host immune system to recognize endogenous CAR in heterodimers...
  18. ncbi request reprint Myocarditis and heart failure associated with hepatitis C virus infection
    Akira Matsumori
    Department of Cardiovascular Medicine, Kyoto University Graduate School of Medicine, Kyoto, Japan
    J Card Fail 12:293-8. 2006
    ..HCV infection has recently been noted in patients with cardiomyopathies and myocarditis. However, prevalence of HCV infection in myocarditis and heart failure remains to be clarified...