Duygu Tosun

Summary

Affiliation: University of California
Country: USA

Publications

  1. pmc MRI patterns of atrophy and hypoperfusion associations across brain regions in frontotemporal dementia
    Duygu Tosun
    Center for Imaging Neurodegenerative Diseases, Veterans Affairs Medical Center, San Francisco, CA 94121, USA
    Neuroimage 59:2098-109. 2012
  2. pmc Spatial patterns of brain amyloid-beta burden and atrophy rate associations in mild cognitive impairment
    Duygu Tosun
    Center for Imaging Neurodegenerative Diseases, Department of Veterans Affairs Medical Centre, 4150 Clement Street, Building 13, 114 M, San Francisco, CA 94121, USA
    Brain 134:1077-88. 2011
  3. doi Relationship between CSF biomarkers of Alzheimer's disease and rates of regional cortical thinning in ADNI data
    Duygu Tosun
    Center for Imaging of Neurodegenerative Diseases, Department of Veterans Affairs Medical Center, San Francisco, CA 94121, USA
    J Alzheimers Dis 26:77-90. 2011
  4. pmc Effects of childhood absence epilepsy on associations between regional cortical morphometry and aging and cognitive abilities
    Duygu Tosun
    Center for Imaging Neurodegenerative Diseases, San Francisco, California, USA
    Hum Brain Mapp 32:580-91. 2011
  5. pmc Relations between brain tissue loss, CSF biomarkers, and the ApoE genetic profile: a longitudinal MRI study
    Duygu Tosun
    Center for Imaging of Neurodegenerative Diseases, Department of Veterans Affairs Medical Center, San Francisco, CA 94121, United States
    Neurobiol Aging 31:1340-54. 2010
  6. ncbi Joint analysis of structural and perfusion MRI for cognitive assessment and classification of Alzheimer's disease and normal aging
    Duygu Tosun
    Center for Imaging of Neurodegenerative Diseases, Department of Veterans Affairs Medical Center, San Francisco, CA 94121, USA
    Neuroimage 52:186-97. 2010
  7. pmc An integrated multimodality MR brain imaging study: gray matter tissue loss mediates the association between cerebral hypoperfusion and Alzheimer's disease
    Duygu Tosun
    Imaging Neurodegenerative Diseases, VA Medical Center 114M, 4150 Clement St, San Francisco, CA 94121, USA
    Conf Proc IEEE Eng Med Biol Soc 2009:6981-4. 2009
  8. pmc Intelligence and cortical thickness in children with complex partial seizures
    Duygu Tosun
    Center for Imaging of Neurodegenerative Diseases, San Francisco, CA, USA
    Neuroimage 57:337-45. 2011
  9. ncbi The effect of subsyndromal symptoms of depression and white matter lesions on disability for individuals with mild cognitive impairment
    R Scott Mackin
    Center for Imaging of Neurodegenerative Diseases, Veterans Administration Medical Center, San Francisco, CA Department of Psychiatry, University of California, San Francisco, CA Electronic address
    Am J Geriatr Psychiatry 21:906-14. 2013
  10. pmc Association of brain amyloid-β with cerebral perfusion and structure in Alzheimer's disease and mild cognitive impairment
    Niklas Mattsson
    1 Department of Veterans Affairs Medical Centre, Centre for Imaging of Neurodegenerative Diseases, San Francisco, CA, USA
    Brain 137:1550-61. 2014

Detail Information

Publications24

  1. pmc MRI patterns of atrophy and hypoperfusion associations across brain regions in frontotemporal dementia
    Duygu Tosun
    Center for Imaging Neurodegenerative Diseases, Veterans Affairs Medical Center, San Francisco, CA 94121, USA
    Neuroimage 59:2098-109. 2012
    ....
  2. pmc Spatial patterns of brain amyloid-beta burden and atrophy rate associations in mild cognitive impairment
    Duygu Tosun
    Center for Imaging Neurodegenerative Diseases, Department of Veterans Affairs Medical Centre, 4150 Clement Street, Building 13, 114 M, San Francisco, CA 94121, USA
    Brain 134:1077-88. 2011
    ....
  3. doi Relationship between CSF biomarkers of Alzheimer's disease and rates of regional cortical thinning in ADNI data
    Duygu Tosun
    Center for Imaging of Neurodegenerative Diseases, Department of Veterans Affairs Medical Center, San Francisco, CA 94121, USA
    J Alzheimers Dis 26:77-90. 2011
    ....
  4. pmc Effects of childhood absence epilepsy on associations between regional cortical morphometry and aging and cognitive abilities
    Duygu Tosun
    Center for Imaging Neurodegenerative Diseases, San Francisco, California, USA
    Hum Brain Mapp 32:580-91. 2011
    ....
  5. pmc Relations between brain tissue loss, CSF biomarkers, and the ApoE genetic profile: a longitudinal MRI study
    Duygu Tosun
    Center for Imaging of Neurodegenerative Diseases, Department of Veterans Affairs Medical Center, San Francisco, CA 94121, United States
    Neurobiol Aging 31:1340-54. 2010
    ....
  6. ncbi Joint analysis of structural and perfusion MRI for cognitive assessment and classification of Alzheimer's disease and normal aging
    Duygu Tosun
    Center for Imaging of Neurodegenerative Diseases, Department of Veterans Affairs Medical Center, San Francisco, CA 94121, USA
    Neuroimage 52:186-97. 2010
    ..Compared to reduced rCBF, regional cortical thinning better explained the variability in dementia severity. In conclusion, structural brain alterations compared to physiological variations are the dominant features of MRI in AD...
  7. pmc An integrated multimodality MR brain imaging study: gray matter tissue loss mediates the association between cerebral hypoperfusion and Alzheimer's disease
    Duygu Tosun
    Imaging Neurodegenerative Diseases, VA Medical Center 114M, 4150 Clement St, San Francisco, CA 94121, USA
    Conf Proc IEEE Eng Med Biol Soc 2009:6981-4. 2009
    ....
  8. pmc Intelligence and cortical thickness in children with complex partial seizures
    Duygu Tosun
    Center for Imaging of Neurodegenerative Diseases, San Francisco, CA, USA
    Neuroimage 57:337-45. 2011
    ..Our cross-sectional findings suggest that disruption in normal age-related cortical thickness expression is associated with intelligence in pediatric CPS patients both with average and below average IQ scores...
  9. ncbi The effect of subsyndromal symptoms of depression and white matter lesions on disability for individuals with mild cognitive impairment
    R Scott Mackin
    Center for Imaging of Neurodegenerative Diseases, Veterans Administration Medical Center, San Francisco, CA Department of Psychiatry, University of California, San Francisco, CA Electronic address
    Am J Geriatr Psychiatry 21:906-14. 2013
    ..To assess the effect of subsyndromal symptoms of depression (SSD) on ratings of disability for individuals with mild cognitive impairment (MCI)...
  10. pmc Association of brain amyloid-β with cerebral perfusion and structure in Alzheimer's disease and mild cognitive impairment
    Niklas Mattsson
    1 Department of Veterans Affairs Medical Centre, Centre for Imaging of Neurodegenerative Diseases, San Francisco, CA, USA
    Brain 137:1550-61. 2014
    ..Amyloid-β pathology has different associations with cerebral blood flow and volume, and may cause more loss of blood flow in early stages, whereas volume loss dominates in late disease stages. ..
  11. pmc Nonlinear time course of brain volume loss in cognitively normal and impaired elders
    Norbert Schuff
    Center for Imaging of Neurodegenerative Diseases and VA Medical Center, San Francisco, CA, USA
    Neurobiol Aging 33:845-55. 2012
    ..The approach has potential uses for early detection of AD and differentiation between stable and progressing MCI...
  12. pmc Identifying cognitively healthy elderly individuals with subsequent memory decline by using automated MR temporoparietal volumes
    Gloria C Chiang
    Department of Radiology, University of California, San Francisco, 505 Parnassus Ave, Room M391, San Francisco, CA, 94143, USA
    Radiology 259:844-51. 2011
    ..To determine whether automated temporoparietal brain volumes can be used to accurately predict future memory decline among a multicenter cohort of cognitively healthy elderly individuals...
  13. ncbi Emerging β-amyloid pathology and accelerated cortical atrophy
    Niklas Mattsson
    Department of Veterans Affairs Medical Center, Center for Imaging of Neurodegenerative Diseases, San Francisco, California2Clinical Neurochemistry Laboratory, Institute of Neuroscience and Physiology, The Sahlgrenska Academy, University of Gothenburg, Mol
    JAMA Neurol 71:725-34. 2014
    ..The effect of β-amyloid (Aβ) accumulation on regional structural brain changes in early stages of Alzheimer disease (AD) is not well understood...
  14. pmc Impact of apolipoprotein E4-cerebrospinal fluid β-amyloid interaction on hippocampal volume loss over 1 year in mild cognitive impairment
    Gloria C Chiang
    Department of Radiology, University of California, San Francisco, USA
    Alzheimers Dement 7:514-20. 2011
    ..No studies have considered the effects of amyloid pathology and APOE ɛ4 together on longitudinal volume loss...
  15. pmc Longitudinal changes in white matter disease and cognition in the first year of the Alzheimer disease neuroimaging initiative
    Owen Carmichael
    Department of Neurology, School of Medicine, University of California, Davis, CA, USA
    Arch Neurol 67:1370-8. 2010
    ....
  16. pmc Effects of cerebrospinal fluid proteins on brain atrophy rates in cognitively healthy older adults
    Niklas Mattsson
    Department of Veterans Affairs Medical Center, Center for Imaging of Neurodegenerative Diseases, San Francisco, CA, USA Clinical Neurochemistry Laboratory, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Molndal, Sweden Department of Radiology and Biomedical Imaging, University of California, San Francisco, CA, USA Electronic address
    Neurobiol Aging 35:614-22. 2014
    ..Proteins interacting with CSF Aβ42 may be related to Aβ brain pathology, whereas proteins associated with atrophy even after adjusting for CSF Aβ42 may be related to Aβ-independent mechanisms. ..
  17. pmc Deformation-based morphometry of prospective neurodevelopmental changes in new onset paediatric epilepsy
    Duygu Tosun
    Centre for Imaging of Neurodegenerative Diseases, San Francisco VA Medical Centre, San Francisco, CA, USA
    Brain 134:1003-14. 2011
    ....
  18. pmc Effects of baseline CSF α-synuclein on regional brain atrophy rates in healthy elders, mild cognitive impairment and Alzheimer's disease
    Niklas Mattsson
    Department of Veterans Affairs Medical Center, Center for Imaging of Neurodegenerative Diseases, San Francisco, California, United States of America Clinical Neurochemistry Laboratory, Institute of Neuroscience and Physiology, The Sahlgrenska Academy at the University of Gothenburg, Molndal, Sweden Department of Radiology and Biomedical Imaging, University of California, San Francisco, California, United States of America
    PLoS ONE 8:e85443. 2013
    ..Here we tested if baseline CSF α-synuclein affects brain atrophy rates and if these effects vary across brain regions, and across the cognitive spectrum from healthy elders (NL), to patients with mild cognitive impairment (MCI) and AD...
  19. pmc Patterns of reduced cortical thickness in late-life depression and relationship to psychotherapeutic response
    R Scott Mackin
    Center for Imaging of Neurodegenerative Diseases, Veterans Administration Medical Center, University of California, San Francisco, CA Department of Psychiatry, University of California, San Francisco, CA Electronic address
    Am J Geriatr Psychiatry 21:794-802. 2013
    ..This study was conducted to evaluate patterns of cortical thickness in LLD and in relation to psychotherapy treatment outcomes...
  20. ncbi 3-D analysis of cortical morphometry in differential diagnosis of Parkinson's plus syndromes: mapping frontal lobe cortical atrophy in progressive supranuclear palsy patients
    Duygu Tosun
    Laboratory of Neuro Imaging, UCLA School of Medicine, Los Angeles, CA, USA
    Med Image Comput Comput Assist Interv 10:891-9. 2007
    ..These findings are indicative of the potential use of routine MRI and cortical morphometry in performing differential diagnosis in PSP, MSA and IPD...
  21. pmc Cortical thickness, surface area, and volume of the brain reward system in alcohol dependence: relationships to relapse and extended abstinence
    Timothy C Durazzo
    Department of Radiology and Biomedical Imaging, University of California San Francisco, CA 94121, USA
    Alcohol Clin Exp Res 35:1187-200. 2011
    ..This study compared thickness, surface area, and volume in neocortical components of the BRS among nonsmoking light-drinking controls (controls), individuals who remained abstinent and those who relapsed after treatment...
  22. pmc Locally linear embedding (LLE) for MRI based Alzheimer's disease classification
    Xin Liu
    Center of Imaging of Neurodegenerative Disease, VA Medical Center and the Department of Radiology and Biomedical Imaging University of California, San Francisco, CA, USA Electronic address
    Neuroimage 83:148-57. 2013
    ..The improvement in predicting conversion to AD in MCI could have important implications for health management and for powering therapeutic trials by targeting non-demented subjects who later convert to AD...
  23. pmc Joint assessment of structural, perfusion, and diffusion MRI in Alzheimer's disease and frontotemporal dementia
    Yu Zhang
    Center for Imaging of Neurodegenerative Diseases, Department of Veterans Affairs San Francisco VA, Medical Center, 4150, Clement Street, San Francisco, CA 94121, USA
    Int J Alzheimers Dis 2011:546871. 2011
    ..Joint assessments of multimodal MRI have potential value to provide new imaging markers for improved differential diagnoses between FTD and AD...
  24. ncbi Neuroimaging predictors of brain amyloidosis in mild cognitive impairment
    Duygu Tosun
    Department of Radiology and Biomedical Imaging, University of California, San Francisco, San Francisco, CA Veterans Administration Medical Center, Center for Imaging of Neurodegenerative Diseases, San Francisco, CA
    Ann Neurol 74:188-98. 2013
    ..To identify a neuroimaging signature predictive of brain amyloidosis as a screening tool to identify individuals with mild cognitive impairment (MCI) that are most likely to have high levels of brain amyloidosis or to be amyloid-free...