Mauricio Tohen

Summary

Affiliation: University of Texas Health Science Center
Country: USA

Publications

  1. doi Efficacy of olanzapine monotherapy in acute bipolar depression: a pooled analysis of controlled studies
    M Tohen
    University of New Mexico, Health Science Center, Department of Psychiatry, Albuquerque, NM, USA
    J Affect Disord 149:196-201. 2013
  2. doi Randomised, double-blind, placebo-controlled study of olanzapine in patients with bipolar I depression
    Mauricio Tohen
    University of Texas Health Science Center, Division of Mood and Anxiety Disorders, 7526 Louis Pasteur Drive, San Antonio, TX 78229 3900, USA
    Br J Psychiatry 201:376-82. 2012
  3. doi Variables as mediators or moderators in predicting relapse to any type of mood episode in a bipolar maintenance study
    Mauricio Tohen
    Division of Mood and Anxiety Disorders, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA
    J Clin Psychiatry 73:e913-7. 2012
  4. doi Olanzapine/fluoxetine combination in patients with treatment-resistant depression: rapid onset of therapeutic response and its predictive value for subsequent overall response in a pooled analysis of 5 studies
    Mauricio Tohen
    University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA
    J Clin Psychiatry 71:451-62. 2010
  5. doi Number needed to treat or harm analyses of olanzapine for maintenance treatment of bipolar disorder
    Mauricio Tohen
    Division of Mood and Anxiety Disorders, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Dr, MSC 7792, San Antonio, TX 78229 390, USA
    J Clin Psychopharmacol 29:520-8. 2009
  6. doi Baseline characteristics and outcomes in patients with first episode or multiple episodes of acute mania
    Mauricio Tohen
    Division of Mood and Anxiety Disorders, University of Texas Health Science Center at San Antonio, 7526 Louis Pasteur Drive, San Antonio, TX 78229 3900, USA
    J Clin Psychiatry 71:255-61. 2010
  7. ncbi The International Society for Bipolar Disorders (ISBD) Task Force report on the nomenclature of course and outcome in bipolar disorders
    Mauricio Tohen
    Department of Psychiatry, Division of Mood and Anxiety Disorders, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, MC 7792, San Antonio, TX 78229, USA
    Bipolar Disord 11:453-73. 2009
  8. doi Antipsychotic agents in the treatment of bipolar mania
    Mauricio Tohen
    Division of Mood and Anxiety Disorders, The University of Texas Health Science Center, San Antonio TX 78229, USA
    Bipolar Disord 11:45-54. 2009
  9. doi Two-year outcomes in first-episode psychotic depression the McLean-Harvard First-Episode Project
    Mauricio Tohen
    University of Texas Health Science Center at San Antonio, TX 78229, USA
    J Affect Disord 136:1-8. 2012
  10. ncbi Randomized, double-blind trial of olanzapine versus placebo in patients prodromally symptomatic for psychosis
    Thomas H McGlashan
    Department of Psychiatry, Yale University School of Medicine, 301 Cedar St, New Haven, CT 06519, USA
    Am J Psychiatry 163:790-9. 2006

Detail Information

Publications26

  1. doi Efficacy of olanzapine monotherapy in acute bipolar depression: a pooled analysis of controlled studies
    M Tohen
    University of New Mexico, Health Science Center, Department of Psychiatry, Albuquerque, NM, USA
    J Affect Disord 149:196-201. 2013
    ..The efficacy and safety of olanzapine monotherapy in bipolar depression has been evaluated in 2 placebo-controlled studies...
  2. doi Randomised, double-blind, placebo-controlled study of olanzapine in patients with bipolar I depression
    Mauricio Tohen
    University of Texas Health Science Center, Division of Mood and Anxiety Disorders, 7526 Louis Pasteur Drive, San Antonio, TX 78229 3900, USA
    Br J Psychiatry 201:376-82. 2012
    ..Atypical antipsychotics are widely used in bipolar mania. However, the efficacy of atypical antipsychotics in bipolar depression has not been comprehensively explored...
  3. doi Variables as mediators or moderators in predicting relapse to any type of mood episode in a bipolar maintenance study
    Mauricio Tohen
    Division of Mood and Anxiety Disorders, University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA
    J Clin Psychiatry 73:e913-7. 2012
    ..The aim was to identify moderators that precede and influence other variables to affect relapse and mediators that explain how or why a second variable affects relapse...
  4. doi Olanzapine/fluoxetine combination in patients with treatment-resistant depression: rapid onset of therapeutic response and its predictive value for subsequent overall response in a pooled analysis of 5 studies
    Mauricio Tohen
    University of Texas Health Science Center at San Antonio, San Antonio, TX 78229, USA
    J Clin Psychiatry 71:451-62. 2010
    ....
  5. doi Number needed to treat or harm analyses of olanzapine for maintenance treatment of bipolar disorder
    Mauricio Tohen
    Division of Mood and Anxiety Disorders, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Dr, MSC 7792, San Antonio, TX 78229 390, USA
    J Clin Psychopharmacol 29:520-8. 2009
    ..Clinicians should consider these and other potential benefits and risks in using maintenance treatments for patients with a bipolar disorder...
  6. doi Baseline characteristics and outcomes in patients with first episode or multiple episodes of acute mania
    Mauricio Tohen
    Division of Mood and Anxiety Disorders, University of Texas Health Science Center at San Antonio, 7526 Louis Pasteur Drive, San Antonio, TX 78229 3900, USA
    J Clin Psychiatry 71:255-61. 2010
    ..The goal of the present analyses was to describe and compare the baseline characteristics, response to treatment, and medication patterns in adult patients experiencing a first episode versus multiple episodes of mania...
  7. ncbi The International Society for Bipolar Disorders (ISBD) Task Force report on the nomenclature of course and outcome in bipolar disorders
    Mauricio Tohen
    Department of Psychiatry, Division of Mood and Anxiety Disorders, University of Texas Health Science Center at San Antonio, 7703 Floyd Curl Drive, MC 7792, San Antonio, TX 78229, USA
    Bipolar Disord 11:453-73. 2009
    ....
  8. doi Antipsychotic agents in the treatment of bipolar mania
    Mauricio Tohen
    Division of Mood and Anxiety Disorders, The University of Texas Health Science Center, San Antonio TX 78229, USA
    Bipolar Disord 11:45-54. 2009
    ..Antipsychotics have been widely used in the treatment of bipolar mania. The purpose of this manuscript was to briefly review the evidence of typical and atypical antipsychotics for the treatment of bipolar mania...
  9. doi Two-year outcomes in first-episode psychotic depression the McLean-Harvard First-Episode Project
    Mauricio Tohen
    University of Texas Health Science Center at San Antonio, TX 78229, USA
    J Affect Disord 136:1-8. 2012
    ..Early assessment can guide accurate diagnosis, prognosis, and treatment-planning for patients with major mental illnesses. Longitudinal studies in psychotic depression from onset are rare, encouraging the present study...
  10. ncbi Randomized, double-blind trial of olanzapine versus placebo in patients prodromally symptomatic for psychosis
    Thomas H McGlashan
    Department of Psychiatry, Yale University School of Medicine, 301 Cedar St, New Haven, CT 06519, USA
    Am J Psychiatry 163:790-9. 2006
    ..This study assessed the efficacy of olanzapine in delaying or preventing conversion to psychosis and reducing symptoms in people with prodromal symptoms of schizophrenia...
  11. doi Neuropsychological course in the prodrome and first episode of psychosis: findings from the PRIME North America Double Blind Treatment Study
    Keith A Hawkins
    Department of Psychiatry, Yale University School of Medicine, New Haven, CT 06519, USA
    Schizophr Res 105:1-9. 2008
    ..We investigated whether conversion to psychosis and/or olanzapine altered the neuropsychological course of subjects within the first-ever double blind medication study of the putative schizophrenia first episode prodrome...
  12. pmc McLean-Harvard International First-Episode Project: two-year stability of DSM-IV diagnoses in 500 first-episode psychotic disorder patients
    Paola Salvatore
    Department of Psychiatry, Harvard Medical School, Boston, MA, USA
    J Clin Psychiatry 70:458-66. 2009
    ..Since stability of DSM-IV diagnoses of disorders with psychotic features requires validation, we evaluated psychotic patients followed systematically in the McLean-Harvard International First Episode Project...
  13. ncbi Predictors of antipsychotic medication adherence in patients recovering from a first psychotic episode
    Diana O Perkins
    Department of Psychiatry, C B 7160, University of North Carolina School of Medicine, Chapel Hill, 27599 7160, USA
    Schizophr Res 83:53-63. 2006
    ..Factors associated with treatment adherence in patients with chronic schizophrenia include beliefs about severity of illness and need for treatment, treatment with typical versus atypical antipsychotic and medication side effects...
  14. ncbi Comparative efficacy and safety of atypical and conventional antipsychotic drugs in first-episode psychosis: a randomized, double-blind trial of olanzapine versus haloperidol
    Jeffrey A Lieberman
    Department of Psychiatry, University of North Carolina School of Medicine, NC 27599 7160, USA
    Am J Psychiatry 160:1396-404. 2003
    ..This study compared the acute and long-term effectiveness of haloperidol with that of olanzapine in patients with first-episode psychosis in a large, controlled clinical trial...
  15. ncbi Analyses of treatment-emergent mania with olanzapine/fluoxetine combination in the treatment of bipolar depression
    Paul E Keck
    Psychopharmacology Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, OH 45267, USA
    J Clin Psychiatry 66:611-6. 2005
    ..These subanalyses compare treatment-emergent mania rates in bipolar I depressed patients treated with olanzapine, placebo, or olanzapine/fluoxetine combination...
  16. pmc Dissimilar morbidity following initial mania versus mixed-states in type-I bipolar disorder
    Ross J Baldessarini
    Department of Psychiatry, Harvard Medical School, Boston, MA, USA
    J Affect Disord 126:299-302. 2010
    ..Mixed-states of bipolar disorders (BPD) may predict worse future illness and more depressive than manic morbidity, challenging a tendency to conflate mixed-states and mania...
  17. ncbi Suicidal events and accidents in 216 first-episode bipolar I disorder patients: predictive factors
    Hari Mandir Kaur Khalsa
    Department of Psychiatry, Harvard Medical School, Mailman Research Center, McLean Division of Massachusetts General Hospital, Belmont, MA 02478 9106, USA
    J Affect Disord 106:179-84. 2008
    ..Risks of life-threatening behaviors are high among bipolar disorder (BPD) patients, but early rates and associated risk factors for suicides and accidents remain ill-defined...
  18. ncbi Substance abuse in first-episode bipolar I disorder: indications for early intervention
    Christopher Baethge
    Department of Psychiatry, Harvard Medical School, Boston, MA, USA
    Am J Psychiatry 162:1008-10. 2005
    ..This study clarified the early characteristics of substance use disorders in patients with first-episode bipolar I disorder...
  19. doi Morbidity in 303 first-episode bipolar I disorder patients
    Ross J Baldessarini
    Department of Psychiatry, Harvard Medical School, Boston, MA, USA
    Bipolar Disord 12:264-70. 2010
    ....
  20. ncbi Weight gain during treatment of bipolar I patients with olanzapine
    John Hennen
    Department of Psychiatry, Harvard Medical School, Boston, MA, USA
    J Clin Psychiatry 65:1679-87. 2004
    ..Body weight increase during long-term treatment with olanzapine in schizophrenia patients is well documented, but weight gain and its association with other medical measures are less well evaluated in bipolar disorder patients...
  21. ncbi An excitement subscale of the Positive and Negative Syndrome Scale
    Jean Pierre Lindenmayer
    Department of Psychiatry, New York University School of Medicine, and Manhattan Psychiatric Center, Wards Island Complex, New York, NY, USA
    Schizophr Res 68:331-7. 2004
    ....
  22. ncbi Randomized trial of olanzapine versus placebo in the symptomatic acute treatment of the schizophrenic prodrome
    Scott W Woods
    Department of Psychiatry, Yale University School of Medicine, New Haven, Connecticut 06519, USA
    Biol Psychiatry 54:453-64. 2003
    ..The prodromal phase of schizophrenic disorders has been described prospectively. The present study aimed to determine the short-term efficacy and safety of olanzapine treatment of prodromal symptoms compared with placebo...
  23. ncbi Capgras' syndrome in first-episode psychotic disorders
    Paola Salvatore
    Department of Psychiatry, Harvard Medical School, Boston, Mass, USA
    Psychopathology 47:261-9. 2014
    ..Conclusions: Capgras' syndrome was prevalent across a broad spectrum of first-episode psychotic disorders, most often in acute psychoses of rapid onset. © 2014 S. Karger AG, Basel. ..
  24. ncbi Rates and predictors of developing a manic or hypomanic episode 1 to 2 years following a first hospitalization for major depression with psychotic features
    Melissa P DelBello
    The Bipolar and Psychotic Disorders Research Program, Department of Psychiatry, University of Cincinnati College of Medicine, Cincinnati, Ohio 45267 0559, USA
    J Child Adolesc Psychopharmacol 13:173-85. 2003
    ....
  25. ncbi Efficacy of olanzapine monotherapy in the treatment of bipolar depression with mixed features
    Mauricio Tohen
    University of New Mexico, Health Sciences Center, Department of Psychiatry, Albuquerque, NM, USA
    J Affect Disord 164:57-62. 2014
    ..This analysis investigated the correlations between the efficacy of olanzapine monotherapy and the number of concurrent manic symptoms in patients treated for bipolar depression...
  26. ncbi Sex differences in clinical response to olanzapine compared with haloperidol
    Jill M Goldstein
    Harvard Institute of Psychiatric Epidemiology and Genetics, Department of Psychiatry, Harvard Medical School at Massachusetts Mental Health Center, MMHC, Boston, MA 02115, USA
    Psychiatry Res 110:27-37. 2002
    ..Finally, premenopausal women had a significantly better treatment response than postmenopausal women, regardless of treatment and chronicity...