Affiliation: University of Colorado Health Sciences Center
- Expression of Galpha14 in sweet-transducing taste cells of the posterior tongueMarco Tizzano
Rocky Mountain Taste and Smell Center, University of Colorado Denver School of Medicine, Aurora, CO 80045, USA
BMC Neurosci 9:110. 2008..We utilized RT-PCR, immunocytochemistry and single-cell gene expression profiling to examine the expression of the Galphaq family (q, 11, 14) in mouse taste buds...
- Expression of taste receptors in solitary chemosensory cells of rodent airwaysMarco Tizzano
Rocky Mountain Taste and Smell Center, Department of Cell and Developmental Biology, University of Colorado at Denver and Health Sciences Center, Aurora, CO, USA
BMC Pulm Med 11:3. 2011..The objective of this study is to map the distribution of SCCs within the airways and to determine the elements of the chemosensory transduction cascade expressed in these SCCs...
- Cholinergic neurotransmission links solitary chemosensory cells to nasal inflammationCecil J Saunders
Rocky Mountain Taste and Smell Center, Department of Cellular and Developmental Biology and Neuroscience Program, University of Colorado School of Medicine, Anschutz Medical Center, Aurora, CO 80045
Proc Natl Acad Sci U S A 111:6075-80. 2014..Taken together, these results show that SCCs use cholinergic neurotransmission to trigger peptidergic trigeminal nociceptors, which link SCCs to the neurogenic inflammatory pathway. ..
- Nasal chemosensory cells use bitter taste signaling to detect irritants and bacterial signalsMarco Tizzano
Rocky Mountain Taste and Smell Center, Department of Cell and Developmental Biology, University of Colorado Denver, Aurora, CO 80045, USA
Proc Natl Acad Sci U S A 107:3210-5. 2010....
- Solitary chemosensory cells and bitter taste receptor signaling in human sinonasal mucosaHenry P Barham
Department of Otolaryngology Head and Neck Surgery, University of Colorado Denver, Aurora, CO 80045, USA
Int Forum Allergy Rhinol 3:450-7. 2013..The purpose of this study was to test for the presence SCCs in human sinonasal epithelium, and to test for a correlation with inflammatory disease processes such as allergic rhinitis and chronic rhinosinusitis...
- Chemosensors in the nose: guardians of the airwaysMarco Tizzano
Department of Cell and Developmental Biology, Rocky Mountain Taste and Smell Center, University of Colorado School of Medicine, Aurora, Colorado, USA
Physiology (Bethesda) 28:51-60. 2013..Here, we describe the different cell types in the airways that utilize taste-receptor signaling to trigger protective epithelial and neural responses to potentially dangerous toxins and bacterial infection...