Robert D Timmerman

Summary

Affiliation: University of Texas Southwestern Medical Center
Country: USA

Publications

  1. ncbi request reprint Observation-only management of early stage, medically inoperable lung cancer: poor outcome
    Ronald C McGarry
    Department of Radiation Oncology, Indiana University, Indianapolis, IN 46202, USA
    Chest 121:1155-8. 2002
  2. pmc Stereotactic body radiation therapy for inoperable early stage lung cancer
    Robert Timmerman
    Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
    JAMA 303:1070-6. 2010
  3. ncbi request reprint Gamma knife stereotactic radiosurgery for low-grade astrocytomas
    Mark A Henderson
    Department of Radiation Oncology, Indiana University Medical Center, Indianapolis, IN 46202, USA
    Stereotact Funct Neurosurg 87:161-7. 2009
  4. doi request reprint An overview of hypofractionation and introduction to this issue of seminars in radiation oncology
    Robert D Timmerman
    Semin Radiat Oncol 18:215-22. 2008
  5. ncbi request reprint Lung cancer: a model for implementing stereotactic body radiation therapy into practice
    Robert Timmerman
    Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9183, USA
    Front Radiat Ther Oncol 40:368-85. 2007
  6. doi request reprint A Radiation Oncologist's and Thoracic Surgeon's View on the Role of Stereotactic Ablative Radiotherapy for Operable Lung Cancer
    Robert D Timmerman
    Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, Texas Electronic address
    Semin Thorac Cardiovasc Surg 25:8-13. 2013
  7. ncbi request reprint Optimizing dose and fractionation for stereotactic body radiation therapy. Normal tissue and tumor control effects with large dose per fraction
    Robert Timmerman
    Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9183, USA
    Front Radiat Ther Oncol 40:352-65. 2007
  8. doi request reprint Local surgical, ablative, and radiation treatment of metastases
    Robert D Timmerman
    University of Texas Southwestern Medical Center, Dallas, TX 75390 9183, USA
    CA Cancer J Clin 59:145-70. 2009
  9. ncbi request reprint The North American experience with stereotactic body radiation therapy in non-small cell lung cancer
    Robert D Timmerman
    Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9183, USA
    J Thorac Oncol 2:S101-12. 2007
  10. ncbi request reprint Stereotactic body radiation therapy: a treatment in need of basic biological research
    Robert D Timmerman
    Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9183, USA
    Cancer J 12:19-20. 2006

Detail Information

Publications83

  1. ncbi request reprint Observation-only management of early stage, medically inoperable lung cancer: poor outcome
    Ronald C McGarry
    Department of Radiation Oncology, Indiana University, Indianapolis, IN 46202, USA
    Chest 121:1155-8. 2002
    ..To assess the treatments received and outcomes of patients with early stage non-small cell lung carcinoma (NSCLC)...
  2. pmc Stereotactic body radiation therapy for inoperable early stage lung cancer
    Robert Timmerman
    Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
    JAMA 303:1070-6. 2010
    ..Patients with early stage but medically inoperable lung cancer have a poor rate of primary tumor control (30%-40%) and a high rate of mortality (3-year survival, 20%-35%) with current management...
  3. ncbi request reprint Gamma knife stereotactic radiosurgery for low-grade astrocytomas
    Mark A Henderson
    Department of Radiation Oncology, Indiana University Medical Center, Indianapolis, IN 46202, USA
    Stereotact Funct Neurosurg 87:161-7. 2009
    ..Only 2 patients experienced symptomatic treatment-related toxicity. GKSRS can provide local control in cases of unresectable or recurrent LGA with a low incidence of side effects in carefully selected patients...
  4. doi request reprint An overview of hypofractionation and introduction to this issue of seminars in radiation oncology
    Robert D Timmerman
    Semin Radiat Oncol 18:215-22. 2008
  5. ncbi request reprint Lung cancer: a model for implementing stereotactic body radiation therapy into practice
    Robert Timmerman
    Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9183, USA
    Front Radiat Ther Oncol 40:368-85. 2007
    ..While mechanisms of this injury remain elusive, ongoing prospective trials offer the hope of finding the ideal application for SBRT in treating pulmonary targets...
  6. doi request reprint A Radiation Oncologist's and Thoracic Surgeon's View on the Role of Stereotactic Ablative Radiotherapy for Operable Lung Cancer
    Robert D Timmerman
    Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, Texas Electronic address
    Semin Thorac Cardiovasc Surg 25:8-13. 2013
    ....
  7. ncbi request reprint Optimizing dose and fractionation for stereotactic body radiation therapy. Normal tissue and tumor control effects with large dose per fraction
    Robert Timmerman
    Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9183, USA
    Front Radiat Ther Oncol 40:352-65. 2007
    ..Hopefully, it will serve as a motivation for more sophisticated biological research into the effects of SBRT...
  8. doi request reprint Local surgical, ablative, and radiation treatment of metastases
    Robert D Timmerman
    University of Texas Southwestern Medical Center, Dallas, TX 75390 9183, USA
    CA Cancer J Clin 59:145-70. 2009
    ..Rather than eliminating the need for local therapies, improvements in systemic therapies appear to be increasing the prudent utilization of modern local therapies in patients presenting with more advanced cancer...
  9. ncbi request reprint The North American experience with stereotactic body radiation therapy in non-small cell lung cancer
    Robert D Timmerman
    Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9183, USA
    J Thorac Oncol 2:S101-12. 2007
    ..In North America, the majority of prospective investigation using stereotactic body radiation therapy (SBRT) for thoracic targets has been carried out treating medically inoperable patients with non-small cell lung cancer...
  10. ncbi request reprint Stereotactic body radiation therapy: a treatment in need of basic biological research
    Robert D Timmerman
    Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9183, USA
    Cancer J 12:19-20. 2006
  11. ncbi request reprint Accreditation and quality assurance for Radiation Therapy Oncology Group: Multicenter clinical trials using Stereotactic Body Radiation Therapy in lung cancer
    Robert Timmerman
    Department of Radiation Oncology, The University of Texas Southwestern Medical Center, Dallas, TX 75390 9183, USA
    Acta Oncol 45:779-86. 2006
    ..The development of RTOG 0618 using SBRT in operable patients with early stage NSCLC is a testament to both the enthusiasm from already published works and prospective multicenter clinical testing using SBRT techniques...
  12. ncbi request reprint Excessive toxicity when treating central tumors in a phase II study of stereotactic body radiation therapy for medically inoperable early-stage lung cancer
    Robert Timmerman
    Department of Radiation Oncology, The University of Texas Southwestern Medical Center, 5801 Forest Park Rd, Dallas, TX 75390 9183, USA
    J Clin Oncol 24:4833-9. 2006
    ..Building on a previously reported phase I trial, we carried out a prospective phase II trial using stereotactic body radiation therapy (SBRT) in this population...
  13. ncbi request reprint Stereotactic body radiation therapy in multiple organ sites
    Robert D Timmerman
    Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9183, USA
    J Clin Oncol 25:947-52. 2007
    ..Stereotactic body radiation therapy (SBRT) uses advanced technology to deliver a potent ablative dose to deep-seated tumors in the lung, liver, spine, pancreas, kidney, and prostate...
  14. ncbi request reprint Extracranial stereotactic radiation delivery
    Robert D Timmerman
    Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas 75390 9183, USA
    Semin Radiat Oncol 15:202-7. 2005
    ..Clinical results already show that SBRT constitutes a new paradigm in cancer treatment that deserves careful implementation and assessment for the improvement in patient outcomes...
  15. doi request reprint Stereotactic body radiation therapy: normal tissue and tumor control effects with large dose per fraction
    Robert Timmerman
    Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, Tex, USA
    Front Radiat Ther Oncol 43:382-94. 2011
    ....
  16. doi request reprint Stereotactic body radiation therapy for thoracic cancers: recommendations for patient selection, setup and therapy
    Robert Timmerman
    Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, Tex, USA
    Front Radiat Ther Oncol 43:395-411. 2011
    ..This chapter will outline many details essential for establishing an effective SBRT program in clinical practice...
  17. doi request reprint Stereotactic body radiation therapy: a novel treatment modality
    Simon S Lo
    Department of Radiation Oncology, Arthur G James Cancer Hospital, Ohio State University College of Medicine, 300 West 10th Avenue, Columbus, OH 43210, USA
    Nat Rev Clin Oncol 7:44-54. 2010
    ..The results of these clinical trials will better define the role of SBRT in cancer management. This article will review the radiobiologic, technical, and clinical aspects of SBRT...
  18. ncbi request reprint Extracranial radiosurgery (stereotactic body radiation therapy) for oligometastases
    Brian D Kavanagh
    Department of Radiation Oncology, University of Colorado Comprehensive Cancer Center, Aurora, CO, USA
    Semin Radiat Oncol 16:77-84. 2006
    ..With proper conduct though, SBRT can be an extremely effective treatment option for oligometastases...
  19. doi request reprint Imaging changes after stereotactic body radiation therapy for lung and liver tumors
    Simon S Lo
    Department of Radiation Oncology, University Hospitals Case Medical Center, Case Western Reserve University, 11100 Euclid Avenue, Lerner Tower B181, Cleveland, OH 44106, USA
    Expert Rev Anticancer Ther 11:613-20. 2011
    ..Since computed tomography and PET are the most commonly used diagnostic imaging tools for monitoring lung tumor and computed tomography for liver tumors, this article will focus on the changes observed on those imaging modalities...
  20. ncbi request reprint Gamma-knife-based stereotactic radiosurgery for uveal melanoma
    Achilles J Fakiris
    Department of Radiation Oncology, Indiana University Medical Center, Indianapolis, USA
    Stereotact Funct Neurosurg 85:106-12. 2007
    ..Gamma-Knife-based SRS appears to provide excellent local control of uveal melanoma. The risk of distant metastasis is significant. Effective systemic therapy is to be explored to improve the treatment outcome of uveal melanoma...
  21. pmc Dosimetric and motion analysis of margin-intensive therapy by stereotactic ablative radiotherapy for resectable pancreatic cancer
    John H Heinzerling
    Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, TX, USA
    Radiat Oncol 6:146. 2011
    ....
  22. ncbi request reprint Interim analysis of a prospective phase I/II trial of SBRT for liver metastases
    Brian D Kavanagh
    Department of Radiation Oncology, University of Colorado, Aurora, Colorado 80045, USA
    Acta Oncol 45:848-55. 2006
    ..This interim analysis indicates that a very high rate of durable in-field tumor control can be safely achieved with SBRT to 1-3 liver lesions as administered in this protocol, to a prescription dose of 60 Gy in 3 fractions...
  23. ncbi request reprint Brachial plexopathy from stereotactic body radiotherapy in early-stage NSCLC: dose-limiting toxicity in apical tumor sites
    Jeffrey A Forquer
    Department of Radiation Oncology, Indiana University School of Medicine, Indianapolis, USA
    Radiother Oncol 93:408-13. 2009
    ..We report frequency of brachial plexopathy in early-stage non-small cell lung cancer treated with stereotactic body radiotherapy...
  24. pmc A pilot trial of serial 18F-fluorodeoxyglucose positron emission tomography in patients with medically inoperable stage I non-small-cell lung cancer treated with hypofractionated stereotactic body radiotherapy
    Mark A Henderson
    Department of Radiation Oncology, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Int J Radiat Oncol Biol Phys 76:789-95. 2010
    ..This report describes PET correlates prospectively collected after stereotactic body radiotherapy (SBRT) for patients with medically inoperable NSCLC...
  25. doi request reprint Universal survival curve and single fraction equivalent dose: useful tools in understanding potency of ablative radiotherapy
    Clint Park
    Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, TX 75390 9183, USA
    Int J Radiat Oncol Biol Phys 70:847-52. 2008
    ....
  26. ncbi request reprint Predictors of rectal tolerance observed in a dose-escalated phase 1-2 trial of stereotactic body radiation therapy for prostate cancer
    D W Nathan Kim
    Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, Texas
    Int J Radiat Oncol Biol Phys 89:509-17. 2014
    ....
  27. doi request reprint Optimization of normalized prescription isodose selection for stereotactic body radiation therapy: conventional vs robotic linac
    Chuxiong Ding
    Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas Texas 75390, USA
    Med Phys 40:051705. 2013
    ..This work aims to determine the optimal prescription isodose line that minimizes normal tissue irradiation for stereotactic body radiation therapy (SBRT) for a conventional linear accelerator and a robotic delivery platform...
  28. ncbi request reprint Stereotactic radiosurgery and fractionated stereotactic radiotherapy in the treatment of uveal melanoma
    Mark A Henderson
    Department of Radiation Oncology, Indiana University Medical Center, Indianapolis, IN, USA
    Technol Cancer Res Treat 5:411-9. 2006
    ..This review summarizes the available literature on these newer treatment modalities...
  29. ncbi request reprint Stereotactic body radiation therapy (stereotactic ablative radiotherapy) for stage I non-small cell lung cancer--updates of radiobiology, techniques, and clinical outcomes
    Mersiha Hadziahmetovic
    Department of Radiation Oncology, Arthur G James Cancer Hospital, Ohio State University, Columbus, OH 43210, USA
    Discov Med 9:411-7. 2010
    ..This article provides updates of these aspects of SBRT for stage I NSCLC...
  30. doi request reprint Endocrine response after gamma knife-based stereotactic radiosurgery for secretory pituitary adenoma
    Brent A Tinnel
    Department of Radiation Oncology, Walter Reed Army Medical Center, Washington, DC, USA
    Stereotact Funct Neurosurg 86:292-6. 2008
    ..To examine treatment outcomes of Gamma Knife-based stereotactic radiosurgery (GK-based SRS) for secretory pituitary adenomas...
  31. ncbi request reprint Stereotactic body radiation therapy for oligometastases
    Simon S Lo
    Department of Radiation Oncology, Arthur G James Cancer Hospital, Ohio State University, Columbus, Ohio 43210, USA
    Discov Med 10:247-54. 2010
    ..Given the high propensity for distant progression, the combination of novel systemic therapy and stereotactic body radiation therapy is to be explored...
  32. ncbi request reprint The role of Gamma Knife Radiosurgery in the management of unresectable gross disease or gross residual disease after surgery in ependymoma
    Simon S Lo
    Department of Radiation Oncology, Indiana University Medical Center, 535 Barnhill Drive, RT 041, Indianapolis, IN 46202, USA
    J Neurooncol 79:51-6. 2006
    ..To evaluate the efficacy and the toxicity of Gamma Knife (GK)-based stereotactic radiosurgery (SRS) in the management of gross disease in ependymoma...
  33. doi request reprint A study on the dosimetric accuracy of treatment planning for stereotactic body radiation therapy of lung cancer using average and maximum intensity projection images
    Long Huang
    Department Radiation Oncology, The University of Texas Southwestern Medical Center, Dallas, TX 75390 9183, USA
    Radiother Oncol 96:48-54. 2010
    ....
  34. ncbi request reprint Stereotactic body radiation therapy of early-stage non-small-cell lung carcinoma: phase I study
    Ronald C McGarry
    Department of Radiation Oncology, Indiana University, Indianapolis, IN 46202, USA
    Int J Radiat Oncol Biol Phys 63:1010-5. 2005
    ..A Phase I dose escalation study of stereotactic body radiation therapy to assess toxicity and local control rates for patients with medically inoperable Stage I lung cancer...
  35. ncbi request reprint Stereotactic ablative radiotherapy (SABR) for non-small cell lung cancer
    Puneeth Iyengar
    Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, Texas
    Semin Respir Crit Care Med 34:845-54. 2013
    ....
  36. ncbi request reprint Gamma knife radiosurgery in the treatment of choroidal neovascularization (wet-type macular degeneration)
    Mark A Henderson
    Department of Radiation Oncology, Indiana University Medical Center, Indianapolis, Ind, USA
    Stereotact Funct Neurosurg 85:11-7. 2007
    ..Further studies are needed to better define the role of GKR in the treatment of macular degeneration...
  37. ncbi request reprint Stereotactic body radiation therapy
    Robert D Timmerman
    Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, Texas, USA
    Curr Probl Cancer 29:120-57. 2005
  38. ncbi request reprint Stereotactic body radiation therapy: a comprehensive review
    Brian K Chang
    Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9183, USA
    Am J Clin Oncol 30:637-44. 2007
    ....
  39. ncbi request reprint A phase II study with cetuximab and radiation therapy for patients with surgically resectable esophageal and GE junction carcinomas: Hoosier Oncology Group G05-92
    Carlos R Becerra
    US Oncology Research, McKesson Specialty Health, The Woodlands, Texas, and Texas Oncology Baylor Sammons Cancer Center, Dallas, Texas Indiana University Melvin and Bren Simon Cancer Center, Indianapolis, Indiana Community Oncology Center, Kokomo, Indiana University of Texas Southwestern Medical Center at Dallas, Dallas, Texas and Indiana University School of Medicine, Indianapolis, Indiana
    J Thorac Oncol 8:1425-9. 2013
    ..This was a phase II, open-label, single-arm, multicenter study of patients with potentially resectable esophageal cancer...
  40. ncbi request reprint Stereotactic ablative radiotherapy for non-small cell lung cancer: rationale and outcomes
    Puneeth Iyengar
    Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, USA
    J Natl Compr Canc Netw 10:1514-20. 2012
    ..Specifically, this review provides the rationale, evidence, and indications for treating early-stage lung cancers with SABR...
  41. doi request reprint Dosimetric and deformation effects of image-guided interventions during stereotactic body radiation therapy of the prostate using an endorectal balloon
    Bernard L Jones
    Department of Radiation Oncology, University of Colorado School of Medicine, Aurora, CO 80045, USA
    Med Phys 39:3080-8. 2012
    ..This work assessed the dosimetric impact of manual interventions on ERB position in patients receiving prostate SBRT and investigated the impact of ERB interventions on prostate shape...
  42. ncbi request reprint Stereotactic body radiation therapy (SBRT) for genitourinary malignancies
    Bin S Teh
    Department of Radiation Oncology, The Methodist Hospital, Houston, Texas 77030, USA
    Discov Med 10:255-62. 2010
    ..Preclinical data, clinical experience, and challenges are reviewed and discussed...
  43. ncbi request reprint Brain metastasis from non-seminomatous germ cell tumor of the testis
    Jeffrey A Forquer
    Indiana University Medical Center, Department of Radiation Oncology, 535 Barnhill Drive, RT041, Indianapolis, IN 46202, USA
    Expert Rev Anticancer Ther 7:1567-80. 2007
    ..This article reviews the literature of the diagnosis and management of brain metastasis from nonseminomatous germ cell tumor of the testis...
  44. doi request reprint Stereotactic body radiation therapy for early-stage non-small-cell lung carcinoma: four-year results of a prospective phase II study
    Achilles J Fakiris
    Department of Radiation Oncology, Indiana University School of Medicine, 535 Barnhill Drive, Indianapolis, IN 46202, USA
    Int J Radiat Oncol Biol Phys 75:677-82. 2009
    ..The 50-month results of a prospective Phase II trial of stereotactic body radiation therapy (SBRT) in medically inoperable patients are reported...
  45. ncbi request reprint Monte carlo simulation of the Leksell Gamma Knife: II. Effects of heterogeneous versus homogeneous media for stereotactic radiosurgery
    Vadim Moskvin
    Department of Radiation Oncology, Indiana University School of Medicine, Indianapolis, IN 46202 5289, USA
    Phys Med Biol 49:4879-95. 2004
    ..This study shows that the employed Monte Carlo treatment planning is more accurate for precise dosimetry of stereotactic radiosurgery with the Leksell Gamma Knife for targets in the vicinity of air-filled cavities...
  46. ncbi request reprint A retrospective analysis of tumor volumetric responses to five-fraction stereotactic radiotherapy for paragangliomas of the head and neck (glomus tumors)
    Stephen G Chun
    Department of Radiation Oncology, Harold C Simmons Cancer Center, University of Texas at Southwestern Medical Center, Dallas, Tex, USA
    Stereotact Funct Neurosurg 92:153-9. 2014
    ..This report describes the results of 31 patients with SBP treated with CyberKnife radiotherapy delivering a total dose of 25 Gray in five fractions...
  47. ncbi request reprint A phase I trial of stereotactic body radiation therapy (SBRT) for liver metastases
    Tracey E Schefter
    Department of Radiation Oncology, University of Colorado Health Sciences Center, Aurora, CO 80045 0510, USA
    Int J Radiat Oncol Biol Phys 62:1371-8. 2005
    ..To determine the maximum tolerated dose (MTD) of stereotactic body radiation therapy (SBRT) for liver metastases...
  48. ncbi request reprint Stereotactic radiosurgery and stereotactic body radiation therapy: an overview of technical considerations and clinical applications
    Brian D Kavanagh
    Department of Radiation Oncology, University of Colorado Comprehensive Cancer Center, 1665 North Ursula Street, Aurora, CO 80045, USA
    Hematol Oncol Clin North Am 20:87-95. 2006
    ..It will be especially interesting to investigate how SRS and SBRT might best be combined with new molecularly targeted systemic agents as the field of oncology progresses through the twenty-first century...
  49. doi request reprint Phosphorus-32 therapy for cystic craniopharyngiomas
    Robert Bryan Barriger
    Department of Radiation Oncology, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Radiother Oncol 98:207-12. 2011
    ..To examine control rates for predominantly cystic craniopharyngiomas treated with intracavitary phosphorus-32 (P-32)...
  50. ncbi request reprint Extracranial stereotactic radioablation: results of a phase I study in medically inoperable stage I non-small cell lung cancer
    Robert Timmerman
    Department of Radiation Oncology, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Chest 124:1946-55. 2003
    ..We set out to investigate a new therapy akin to brain radiosurgery called extracranial stereotactic radioablation (ESR) in a phase I trial...
  51. ncbi request reprint A dosimetric comparison of stereotactic body radiation therapy techniques for lung cancer: robotic versus conventional linac-based systems
    Chuxiong Ding
    Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
    J Appl Clin Med Phys 11:3223. 2010
    ..The results of this study provide a general guideline for patient and treatment modality selection based on dosimetric, tumor and normal tissue sparing considerations...
  52. ncbi request reprint Frame-based immobilization and targeting for stereotactic body radiation therapy
    Bryan Murray
    Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
    Med Dosim 32:86-91. 2007
    ..With the body frame, large-dose-per fraction treatment is possible for localized tumor deposits with the aim of attaining a more therapeutic result...
  53. pmc Dosimetric evaluation of heterogeneity corrections for RTOG 0236: stereotactic body radiotherapy of inoperable stage I-II non-small-cell lung cancer
    Ying Xiao
    Department of Radiation Oncology, Jefferson Medical College, Philadelphia, PA 19107, USA
    Int J Radiat Oncol Biol Phys 73:1235-42. 2009
    ....
  54. ncbi request reprint Hypofractionation in radiation therapy and its impact
    Lech Papiez
    University of Texas Southwestern Medical Center, Dallas, Texas 75390, USA
    Med Phys 35:112-8. 2008
    ....
  55. doi request reprint Multi-staged robotic stereotactic radiosurgery for large cerebral arteriovenous malformations
    Chuxiong Ding
    Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, USA Electronic address
    Radiother Oncol 109:452-6. 2013
    ..The treatment planning process and strategies to optimize both individual and composite dosimetry are discussed...
  56. pmc Isolated central nervous system progression on Crizotinib: an Achilles heel of non-small cell lung cancer with EML4-ALK translocation?
    Stephen G Chun
    Department of Radiation Oncology, Harold C Simmons Comprehensive Cancer Center, University of Texas Southwestern Medical Center, Dallas, TX, USA
    Cancer Biol Ther 13:1376-83. 2012
    ....
  57. ncbi request reprint Cost-effectiveness analysis of SBRT versus IMRT: an emerging initial radiation treatment option for organ-confined prostate cancer
    Joseph C Hodges
    University of Texas Southwestern, Dallas, USA
    Am J Manag Care 18:e186-93. 2012
    ....
  58. doi request reprint Stereotactic ablative radiation therapy for primary lung tumors
    John H Heinzerling
    Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
    Cancer J 17:28-32. 2011
    ....
  59. pmc Radiation dose-volume effects in the lung
    Lawrence B Marks
    Department of Radiation Oncology, University of North Carolina, Chapel Hill, NC 27514, USA
    Int J Radiat Oncol Biol Phys 76:S70-6. 2010
    ..The rate of symptomatic pneumonitis is related to many dosimetric parameters, and there are no evident threshold "tolerance dose-volume" levels. There are strong volume and fractionation effects...
  60. ncbi request reprint American Society for Therapeutic Radiology and Oncology and American College of Radiology practice guideline for the performance of stereotactic body radiation therapy
    Louis Potters
    Department of Radiation Oncology, South Nassau Communities Hospital, Oceanside, NY, USA
    Int J Radiat Oncol Biol Phys 60:1026-32. 2004
  61. ncbi request reprint Extracranial stereotactic radioablation: physical principles
    Lech Papiez
    Department of Radiation Oncology, Indiana University School of Medicine, Indianapolis 46202, USA
    Acta Oncol 42:882-94. 2003
    ..It is also shown that isotropic, highly non-coplanar beam arrangements avoiding oppositional fields allow more optimal fall-off gradients to normal tissue as opposed to coplanar treatments (condition 5)...
  62. doi request reprint Four-dimensional computed tomography scan analysis of tumor and organ motion at varying levels of abdominal compression during stereotactic treatment of lung and liver
    John H Heinzerling
    Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA
    Int J Radiat Oncol Biol Phys 70:1571-8. 2008
    ..To investigate the effectiveness of different abdominal compression levels on tumor and organ motion during stereotactic body radiotherapy of lower lobe lung and liver tumors using four-dimensional (4D)-CT scan analysis...
  63. doi request reprint Baseline pulmonary function as a predictor for survival and decline in pulmonary function over time in patients undergoing stereotactic body radiotherapy for the treatment of stage I non-small-cell lung cancer
    Mark Henderson
    Department of Radiation Oncology, Indiana University School of Medicine, Indianapolis, IN, USA
    Int J Radiat Oncol Biol Phys 72:404-9. 2008
    ....
  64. ncbi request reprint Stereotactic body radiation therapy: evaluation of setup accuracy and targeting methods for a new couch integrated immobilization system
    John H Heinzerling
    Department of Radiation Oncology, University of Texas Southwestern Medical Center, Dallas, TX, USA
    Technol Cancer Res Treat 7:197-206. 2008
    ..With these results, a 5 mm expansion for PTV margins remains the standard for our institution...
  65. ncbi request reprint Extracranial stereotactic radiation delivery: expansion of technology beyond the brain
    Robert Timmerman
    Department of Radiation Oncology, Indiana University School of Medicine, Indianapolis, IN 46202, USA
    Technol Cancer Res Treat 2:153-60. 2003
    ..In addition, this article will summarize the data that exists in the literature to date, that has documented the rationale, and efficacy of this novel therapeutic approach...
  66. pmc Intraduodenal sarcoma recurrence of retroperitoneal origin: an unusual cause for a duodenal obstruction
    Jean J Bao
    Department of Surgery, Division of Surgical Oncology, UT Southwestern Medical Center, Dallas, TX, USA
    World J Surg Oncol 10:59. 2012
    ..This unusual recurrence pattern likely relates to the patient's previous resection and radiation treatment, and highlights the benefits, limitations and follow-up strategies after multimodality treatment...
  67. ncbi request reprint Lung cancer radiation therapy: Monte Carlo investigation of "under dose" by high energy photons
    Paul M DesRosiers
    Department of Radiation Oncology, Indiana University School of Medicine, Indianapolis, IN, USA
    Technol Cancer Res Treat 3:289-94. 2004
    ..The non-coplanar technique with the lower energy photons covered the tumor with a greatest isodose at the tumor periphery without tangential sparing in the coronal plane...
  68. ncbi request reprint The impact of mid-treatment MRI on defining boost volumes in the radiation treatment of glioblastoma multiforme
    Rafael Manon
    University of Wisconsin, Department of Radiation Oncology, K4 B100, 600 Highland Ave, Madison, WI 53792, USA
    Technol Cancer Res Treat 3:303-7. 2004
    ....
  69. pmc An orthotopic lung tumor model for image-guided microirradiation in rats
    Debabrata Saha
    Department of Radiation Oncology, Division of Molecular Radiation Biology and Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, Texas 75390 9187, USA
    Radiat Res 174:62-71. 2010
    ....
  70. doi request reprint Rib fracture following stereotactic body radiotherapy: a potential pitfall
    Sinisa Stanic
    Department of Radiation Oncology, University of California Davis, Sacramento, CA 95817, USA
    Clin Nucl Med 36:e168-70. 2011
    ..Nuclear medicine physicians and diagnostic radiologists should always consider rib fracture in the differential diagnosis...
  71. ncbi request reprint Effect of estrogen on radiation-induced cataractogenesis
    Joseph R Dynlacht
    Department of Radiation Oncology, Indiana University School of Medicine, Indianapolis, Indiana 46202, USA
    Radiat Res 165:9-15. 2006
    ..Taken together, our data suggest that estrogen accelerates progression of radiation-induced opacification...
  72. ncbi request reprint Monte Carlo simulation of the Leksell Gamma Knife: I. Source modelling and calculations in homogeneous media
    Vadim Moskvin
    Department of Radiation Oncology, Indiana University School of Medicine, Indianapolis 46202 5289, USA
    Phys Med Biol 47:1995-2011. 2002
    ..Good agreement was found between these data and results of simulations in homogeneous media. Owing to this established accuracy, PENELOPE is suitable for simulating problems relevant to stereotactic radiosurgery...
  73. pmc Phase I dose-escalation study of stereotactic body radiation therapy for low- and intermediate-risk prostate cancer
    Thomas P Boike
    University of Texas Southwestern, Dallas, TX 75390, USA
    J Clin Oncol 29:2020-6. 2011
    ..To evaluate the tolerability of escalating doses of stereotactic body radiation therapy in the treatment of localized prostate cancer...
  74. ncbi request reprint Efficacy of high dose per fraction radiation for implanted human prostate cancer in a nude mouse model
    Yair Lotan
    Department of Urology, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    J Urol 175:1932-6. 2006
    ..We investigated the dose-response characteristics of SBRT for treating human prostate cancer in a nude mouse model...
  75. ncbi request reprint Efficacy of ablative high-dose-per-fraction radiation for implanted human renal cell cancer in a nude mouse model
    Lance Walsh
    Department of Urology, The University of Texas Southwestern Medical Center, Dallas, Texas 75390 9110, USA
    Eur Urol 50:795-800; discussion 800. 2006
    ..We investigated the use of ablative hypofractionation in treating human renal cell carcinoma using a nude mouse model...
  76. ncbi request reprint Role of stereotactic radiosurgery and fractionated stereotactic radiotherapy in pediatric brain tumors
    Simon S Lo
    Department of Radiation Medicine, Arthur G James Cancer Hospital, Ohio State University Medical Center, 300 West 10th Avenue, Ste 088A, Columbus, OH 43210, USA
    Expert Rev Neurother 8:121-32. 2008
    ..SRS and FSRT can potentially add to the armamentarium against brain tumors in children. This article will review the role of SRS and FSRT in the management of pediatric brain tumors...
  77. ncbi request reprint Stereotactic body radiation therapy for early-stage non-small-cell lung cancer
    Simon S Lo
    Ohio State University Medical Center, Department of Radiation Medicine, Arthur G James Cancer Hospital, 300 West 10th Avenue, Suite 088A, Columbus, OH 43210, USA
    Expert Rev Anticancer Ther 8:87-98. 2008
    ..This article reviews the radiobiologic, physical/technical and clinical aspects of stereotactic body radiation therapy for early-stage non-small-cell lung cancer. The literature is also reviewed...
  78. ncbi request reprint In regard to Donaldson et al: results from the IRS-IV randomized trial of hyperfractionated radiotherapy in children with rhabdomyosarcoma-a report from the IRSG. IJROBP 2001;51:718-728
    Robert D Timmerman
    Int J Radiat Oncol Biol Phys 54:1579-80; author reply 1580. 2002
  79. ncbi request reprint FDG-PET and stereotactic body radiotherapy (SBRT) for stage I non-small-cell lung cancer
    David J Hoopes
    Department of Radiation Oncology, Indiana University School of Medicine, Indianapolis, IN, United States
    Lung Cancer 56:229-34. 2007
    ..To investigate the utility of positron emission tomography (PET) in patients treated with stereotactic body radiotherapy (SBRT) for stage I non-small-cell lung cancer (NSCLC) on prospective institutional trials...
  80. ncbi request reprint Successful treatment of a skull base malignant rhabdoid tumor with surgery, chemotherapy and gamma Knife-based stereotactic radiosurgery in a young child
    Thomas C Witt
    Neurosurgery, Indiana University Medical Center, Indianapolis, Indiana, USA
    Stereotact Funct Neurosurg 85:310-3. 2007
    ..There were no obvious endocrine deficits or growth abnormalities at last follow-up. Gamma Knife-based stereotactic radiosurgery may have a role in the management of very young children with skull base tumors...
  81. ncbi request reprint Use of computed tomography for the fabrication of a custom brachytherapy carrier: a clinical report
    Patrick M Van Derhei
    School of Dentistry, Indiana University, Indianapolis 46202, USA
    J Prosthet Dent 89:15-8. 2003
    ..The indirect procedure eliminated discomfort from impression making and allowed for precise fabrication of the nasopharyngeal carrier. The described technique can be used for other intracavitary radiation applications...
  82. ncbi request reprint Patterns of failure after induction chemotherapy followed by consolidative radiation therapy for children with central nervous system germinoma
    Robert D Timmerman
    Department of Radiation Oncology, Indiana University School of Medicine, Indianapolis, Indiana, IN 46202, USA
    Med Pediatr Oncol 41:564-6. 2003
  83. ncbi request reprint Adjuvant radiation for stage IIb soft tissue sarcoma of the extremity
    Robert D Timmerman
    J Clin Oncol 20:3929-30; author reply 3930. 2002