Tarik Tihan

Summary

Affiliation: University of California
Country: USA

Publications

  1. ncbi request reprint Pathologic and epidemiologic findings of intramedullary spinal cord tumors
    Tarik Tihan
    Department of Pathology, University of California, San Francisco, CA 94143, USA
    Neurosurg Clin N Am 17:7-11. 2006
  2. ncbi request reprint Neural stem cells and their role in the pathology and classification of central nervous system tumors
    Tarik Tihan
    Department of Pathology, University of California San Francisco, San Francisco, USA
    Turk Patoloji Derg 27:1-11. 2011
  3. doi request reprint Pathologic characteristics of pediatric intracranial pilocytic astrocytomas and their impact on outcome in 3 countries: a multi-institutional study
    Tarik Tihan
    Department of Pathology, University of California San Francisco, San Francisco, CA, USA
    Am J Surg Pathol 36:43-55. 2012
  4. ncbi request reprint The prognostic value of histological grading of posterior fossa ependymomas in children: a Children's Oncology Group study and a review of prognostic factors
    Tarik Tihan
    Department of Pathology, University of California, San Francisco, CA 94143 0102, USA
    Mod Pathol 21:165-77. 2008
  5. ncbi request reprint Astrocytic neoplasms of the central nervous system and orbit: a morphologic perspective
    Tarik Tihan
    Department of Pathology, University of California, San Francisco, UCSF School of Medicine, California, 94143 0102, USA
    Semin Diagn Pathol 27:114-21. 2010
  6. doi request reprint Secondary gliosarcoma after diagnosis of glioblastoma: clinical experience with 30 consecutive patients
    Seunggu J Han
    Department of Neurological Surgery, University of California, San Francisco, California 94117, USA
    J Neurosurg 112:990-6. 2010
  7. pmc Inherited variant on chromosome 11q23 increases susceptibility to IDH-mutated but not IDH-normal gliomas regardless of grade or histology
    Terri Rice
    Department of Neurological Surgery, University of California, San Francisco, San Francisco, CA 94107, USA
    Neuro Oncol 15:535-41. 2013
  8. doi request reprint Intracranial hemangiopericytoma: clinical experience and treatment considerations in a modern series of 40 adult patients
    Martin J Rutkowski
    Department of Neurological Surgery, University of California at San Francisco, San Francisco, California, USA
    Cancer 118:1628-36. 2012
  9. doi request reprint Role of extent of resection in the long-term outcome of low-grade hemispheric gliomas
    Justin S Smith
    Department of Neurological Surgery, Brain Tumor Research Center, University of California San Francisco, 505 Parnassus Ave, Room M 779, San Francisco, CA 94143 0112, USA
    J Clin Oncol 26:1338-45. 2008
  10. doi request reprint Management of recurrent intracranial hemangiopericytoma
    Martin J Rutkowski
    Brain Tumor Research Center, Department of Neurological Surgery, University of California San Francisco, San Francisco, CA 94143, USA
    J Clin Neurosci 18:1500-4. 2011

Detail Information

Publications101 found, 100 shown here

  1. ncbi request reprint Pathologic and epidemiologic findings of intramedullary spinal cord tumors
    Tarik Tihan
    Department of Pathology, University of California, San Francisco, CA 94143, USA
    Neurosurg Clin N Am 17:7-11. 2006
  2. ncbi request reprint Neural stem cells and their role in the pathology and classification of central nervous system tumors
    Tarik Tihan
    Department of Pathology, University of California San Francisco, San Francisco, USA
    Turk Patoloji Derg 27:1-11. 2011
    ..We strongly believe that the ever increasing knowledge in the field of neural and brain tumor stem cells should be influential in the subsequent attempts to classify brain tumors...
  3. doi request reprint Pathologic characteristics of pediatric intracranial pilocytic astrocytomas and their impact on outcome in 3 countries: a multi-institutional study
    Tarik Tihan
    Department of Pathology, University of California San Francisco, San Francisco, CA, USA
    Am J Surg Pathol 36:43-55. 2012
    ..This finding has significant implications given its role in oncogen-induced senescence and possible influence on treatment decisions of subtotally resected tumors...
  4. ncbi request reprint The prognostic value of histological grading of posterior fossa ependymomas in children: a Children's Oncology Group study and a review of prognostic factors
    Tarik Tihan
    Department of Pathology, University of California, San Francisco, CA 94143 0102, USA
    Mod Pathol 21:165-77. 2008
    ....
  5. ncbi request reprint Astrocytic neoplasms of the central nervous system and orbit: a morphologic perspective
    Tarik Tihan
    Department of Pathology, University of California, San Francisco, UCSF School of Medicine, California, 94143 0102, USA
    Semin Diagn Pathol 27:114-21. 2010
    ..This short review highlights the most pertinent features of neoplasms considered within this diverse family...
  6. doi request reprint Secondary gliosarcoma after diagnosis of glioblastoma: clinical experience with 30 consecutive patients
    Seunggu J Han
    Department of Neurological Surgery, University of California, San Francisco, California 94117, USA
    J Neurosurg 112:990-6. 2010
    ..The authors present a large series of histologically confirmed SGSs, with follow-up to describe the clinical and radiological presentation, pathological diagnosis, and treatment outcomes...
  7. pmc Inherited variant on chromosome 11q23 increases susceptibility to IDH-mutated but not IDH-normal gliomas regardless of grade or histology
    Terri Rice
    Department of Neurological Surgery, University of California, San Francisco, San Francisco, CA 94107, USA
    Neuro Oncol 15:535-41. 2013
    ..Because the inherited variant in 11q23 has been associated with risk of lower grade glioma and not with glioblastomas, we hypothesized that this variant increases susceptibility to IDH-mutated gliomas, but not to IDH-wild-type gliomas...
  8. doi request reprint Intracranial hemangiopericytoma: clinical experience and treatment considerations in a modern series of 40 adult patients
    Martin J Rutkowski
    Department of Neurological Surgery, University of California at San Francisco, San Francisco, California, USA
    Cancer 118:1628-36. 2012
    ..Intracranial hemangiopericytoma (HPC) is a malignant meningothelial tumor. Because of its rarity, few guidelines exist for optimal management...
  9. doi request reprint Role of extent of resection in the long-term outcome of low-grade hemispheric gliomas
    Justin S Smith
    Department of Neurological Surgery, Brain Tumor Research Center, University of California San Francisco, 505 Parnassus Ave, Room M 779, San Francisco, CA 94143 0112, USA
    J Clin Oncol 26:1338-45. 2008
    ..The prognostic role of extent of resection (EOR) of low-grade gliomas (LGGs) is a major controversy. We designed a retrospective study to assess the influence of EOR on long-term outcomes of LGGs...
  10. doi request reprint Management of recurrent intracranial hemangiopericytoma
    Martin J Rutkowski
    Brain Tumor Research Center, Department of Neurological Surgery, University of California San Francisco, San Francisco, CA 94143, USA
    J Clin Neurosci 18:1500-4. 2011
    ..This multimodality approach also appears to outperform GKS in extending time to second recurrence. Accordingly, when safe and feasible, surgical resection of recurrent HPC with adjuvant EBRT should be the first steps in management...
  11. doi request reprint Spectrum of pilomyxoid astrocytomas: intermediate pilomyxoid tumors
    Michael W Johnson
    Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Am J Surg Pathol 34:1783-91. 2010
    ..Further follow-up is needed to more accurately determine the prognosis of intermediate tumors...
  12. pmc Genetic variants in telomerase-related genes are associated with an older age at diagnosis in glioma patients: evidence for distinct pathways of gliomagenesis
    Kyle M Walsh
    Department of Neurological Surgery, University of California, San Francisco, San Francisco, CA, USA
    Neuro Oncol 15:1041-7. 2013
    ..We examined associations of these 7 established glioma risk loci with age at diagnosis among patients with glioma...
  13. ncbi request reprint Comprehensive management of symptomatic and aggressive vertebral hemangiomas
    Frank L Acosta
    Department of Neurological Surgery, University of California, San Francisco, R505 Parnassus Avenue, Room M 779, San Francisco, CA 94143 0112, USA
    Neurosurg Clin N Am 19:17-29. 2008
    ..Vertebroplasty is useful for improving pain symptoms, especially when vertebral body compression fracture has occurred in patients without neurological deficit, but is less effective in providing long-term pain relief...
  14. pmc The superiority of conservative resection and adjuvant radiation for craniopharyngiomas
    Adam Schoenfeld
    Department of Radiation Oncology, University of California, San Francisco UCSF, San Francisco, CA 94143 1708, USA
    J Neurooncol 108:133-9. 2012
    ..014). In conclusion, for patients with craniopharyngioma, STR + RT may provide superior clinical outcome, achieving better disease control than STR and limiting side effects associated with aggressive surgical resection...
  15. ncbi request reprint Volumetric extent of resection and residual contrast enhancement on initial surgery as predictors of outcome in adult patients with hemispheric anaplastic astrocytoma
    G Evren Keles
    Department of Neurological Surgery, University of California, San Francisco, California 94143 0112, USA
    J Neurosurg 105:34-40. 2006
    ....
  16. pmc Implications for immunotherapy of tumor-mediated T-cell apoptosis associated with loss of the tumor suppressor PTEN in glioblastoma
    James S Waldron
    Department of Neurological Surgery, University of California at San Francisco, San Francisco, California 94123, USA
    J Clin Neurosci 17:1543-7. 2010
    ..In addition, our results raise the possibility of combining T-cell based immunotherapy protocols with clinical inhibitors of the PI3K/Akt/mTOR pathway...
  17. pmc SNPLogic: an interactive single nucleotide polymorphism selection, annotation, and prioritization system
    Alexander R Pico
    Gladstone Institute of Cardiovascular Disease, 1650 Owens Street, San Francisco, CA 94158, USA
    Nucleic Acids Res 37:D803-9. 2009
    ..We have found integration of SNP annotation in the context of pathway information and functional prediction scores to be a powerful approach to the analysis and interpretation of SNP-disease association data...
  18. doi request reprint Surgical resection and adjuvant radiotherapy for a large pineal hemangiopericytoma
    Brian J Jian
    Department of Neurological Surgery, University of California at San Francisco, 505 Parnassus Avenue, San Francisco, CA 94143, USA
    J Clin Neurosci 17:1209-11. 2010
    ..The patient remains recurrence free 4 years after treatment...
  19. doi request reprint Clinical characteristics and outcomes for a modern series of primary gliosarcoma patients
    Seunggu J Han
    Department of Neurological Surgery, University of California, San Francisco, CA, USA
    Cancer 116:1358-66. 2010
    ..In the current study, the authors present a modern series of confirmed PGS cases treated in the era of magnetic resonance imaging (MRI), after the accepted glioblastoma management of resection, radiation, and temozolomide...
  20. doi request reprint Surgical technique of temporary arterial occlusion in the operative management of spinal hemangioblastomas
    Aaron J Clark
    Department of Neurological Surgery, University of California, San Francisco, California, USA
    World Neurosurg 74:200-5. 2010
    ..Although benign, their highly vascular nature makes resection challenging. A major difficulty involves intraoperative differentiation of vessels supplying the tumor from those supplying the spinal cord...
  21. pmc Voltage-gated potassium channel EAG2 controls mitotic entry and tumor growth in medulloblastoma via regulating cell volume dynamics
    Xi Huang
    Howard Hughes Medical Institute, San Francisco, CA 94158, USA
    Genes Dev 26:1780-96. 2012
    ....
  22. pmc SSBP2 variants are associated with survival in glioblastoma patients
    Yuanyuan Xiao
    Department of Epidemiology and Biostatistics, University of California, San Francisco 185 Berry St, Suite 5700, San Francisco, CA 94107, USA
    Clin Cancer Res 18:3154-62. 2012
    ..Glioblastoma is a devastating, incurable disease with few known prognostic factors. Here, we present the first genome-wide survival and validation study for glioblastoma...
  23. pmc Chemotherapy-induced apoptosis in a transgenic model of neuroblastoma proceeds through p53 induction
    Louis Chesler
    Department of Pediatrics, University of California, San Francisco, San Francisco, CA 94143, USA
    Neoplasia 10:1268-74. 2008
    ....
  24. doi request reprint Post-radiation reactive changes in a single vertebral body mimicking metastatic pineoblastoma
    Matthew C Tate
    Departments of Neurological Surgery, University of California San Francisco, California, USA
    J Neurosurg Pediatr 4:479-83. 2009
    ..To the authors' knowledge this is the first reported case of reactive changes mimicking metastasis in a single vertebral body following standard therapy for resected primary pineoblastoma...
  25. doi request reprint Early surgical intervention in adult patients with ganglioglioma is associated with improved clinical seizure outcomes
    Isaac Yang
    Department of Neurological Surgery, University of California at Los Angeles, Los Angeles, California, USA
    J Clin Neurosci 18:29-33. 2011
    ..Our findings also support that an early surgical intervention is significantly associated with improved clinical seizure control...
  26. pmc DNA hypermethylation profiles associated with glioma subtypes and EZH2 and IGFBP2 mRNA expression
    Shichun Zheng
    Department of Neurological Surgery, University of California San Francisco, Helen Diller Family Cancer Center, 1450 3rd Street, San Francisco, CA 94158, USA
    Neuro Oncol 13:280-9. 2011
    ..DNA methylation markers are useful in characterizing distinct glioma subtypes and may hold promise for clinical applications...
  27. doi request reprint Diagnostic implications of IDH1-R132H and OLIG2 expression patterns in rare and challenging glioblastoma variants
    Nancy M Joseph
    Department of Pathology, University of California San Francisco, San Francisco, CA 94143, USA
    Mod Pathol 26:315-26. 2013
    ..Therefore, in one of the most challenging differential diagnoses, IDH1 positivity could provide strong support for glioblastoma with oligodendroglial component, while essentially excluding small cell glioblastoma...
  28. doi request reprint Transmantle sign in focal cortical dysplasia: a unique radiological entity with excellent prognosis for seizure control
    Doris D Wang
    Department of Neurological Surgery, University of California, San Francisco, 505 Parnassus Avenue, M779, San Francisco, California 94143, USA
    J Neurosurg 118:337-44. 2013
    ..The aim of this study was to characterize seizure control outcomes and prognostic significance of the transmantle sign in FCD epilepsy...
  29. doi request reprint Immune cell infiltrate differences in pilocytic astrocytoma and glioblastoma: evidence of distinct immunological microenvironments that reflect tumor biology
    Isaac Yang
    Department of Neurosurgery, University of California, Los Angeles, California, USA
    J Neurosurg 115:505-11. 2011
    ..In this paper the authors demonstrate that characterization of the intratumoral inflammatory infiltrate can distinguish high-grade glioblastoma from low-grade pilocytic astrocytoma...
  30. doi request reprint Frequent gains at chromosome 7q34 involving BRAF in pilocytic astrocytoma
    Eli E Bar
    Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    J Neuropathol Exp Neurol 67:878-87. 2008
    ..These data indicate that focal gains at chromosome 7q34 and increased BRAF-MEK-ERK signaling are common findings in sporadic pilocytic astrocytomas...
  31. pmc Methylation of the PTEN promoter defines low-grade gliomas and secondary glioblastoma
    John K Wiencke
    Department of Neurological Surgery and Brain Tumor Research Center, University of California, San Francisco, San Francisco, CA 94143, USA
    Neuro Oncol 9:271-9. 2007
    ....
  32. doi request reprint Adjuvant radiation therapy and chondroid chordoma subtype are associated with a lower tumor recurrence rate of cranial chordoma
    Brian J Jian
    Department of Neurological Surgery, University of California at San Francisco, 505, Parnassus Ave, San Francisco, CA 94143, USA
    J Neurooncol 98:101-8. 2010
    ..Our data suggests that younger patients with chondroid type cranial chordoma treated with both surgery and radiation may have improved rates of tumor recurrence in the treatment of these tumors...
  33. doi request reprint The next step: innovative molecular targeted therapies for treatment of intracranial chordoma patients
    Jeffrey J Barry
    Department of Neurological Surgery, University of California at San Francisco, San Francisco, California 94117, USA
    Neurosurgery 68:231-40; discussion 240-1. 2011
    ..Patients who relapse or cannot undergo a complete en bloc resection generally have a poor prognosis. New agents for postoperative adjuvant treatment of chordomas are needed...
  34. ncbi request reprint Biomarkers to predict response to epidermal growth factor receptor inhibitors
    Daphne A Haas-Kogan
    Department of Radiation Oncology, University of California San Francisco, USA
    Cell Cycle 4:1369-72. 2005
    ..Ultimately the goal of these studies is to allow selection of patients who will preferentially respond to EGFR inhibitors...
  35. pmc Pleiotropic role for MYCN in medulloblastoma
    Fredrik J Swartling
    University of California at San Francisco, San Francisco, California 94158, USA
    Genes Dev 24:1059-72. 2010
    ..Targeted expression of MYCN thus contributes to initiation, progression, and maintenance of MB, suggesting a central role for MYCN in pathogenesis...
  36. doi request reprint Intratumoral hemorrhage and fibrosis in vestibular schwannoma: a possible mechanism for hearing loss
    Michael E Sughrue
    Department of Neurological Surgery, University of California, San Francisco, 94143, USA
    J Neurosurg 114:386-93. 2011
    ..In this case-control study, the authors investigated the relationship between preoperative hearing loss and histological changes such as intratumoral microhemorrhage and extensive fibrosis...
  37. pmc CD8+ T-cell infiltrate in newly diagnosed glioblastoma is associated with long-term survival
    Isaac Yang
    Department of Neurological Surgery, University of California at San Francisco, 505 Parnassus Avenue, San Francisco, California 94117, USA
    J Clin Neurosci 17:1381-5. 2010
    ..006). Thus, CD8+ T-cell infiltrate is associated with prolonged survival. Our data provide the impetus for more sophisticated studies to further elucidate prospectively the specific T-cell subtypes associated with long-term survival...
  38. doi request reprint Evidence of ambiguous differentiation and mTOR pathway dysregulation in subependymal giant cell astrocytoma
    Brad D Barrows
    Department of Pathology, University of California San Francisco, San Francisco, USA
    Turk Patoloji Derg 28:95-103. 2012
    ..Inactivation leads to loss of proteins that inhibit mammalian target of rapamycin (mTOR ) disrupting tightly regulated cell functions...
  39. pmc High-dose chemotherapy and autologous stem cell rescue for atypical teratoid/rhabdoid tumor of the central nervous system
    Theodore Nicolaides
    Department of Pediatrics, University of California San Francisco School of Medicine, 505 Parnassus Avenue, M649, Box 0106, San Francisco, CA 94143, USA
    J Neurooncol 98:117-23. 2010
    ..Two of nine patients treated for AT/RT at our institution with high dose chemotherapy and autologous bone marrow transplant are long-term survivors, suggesting that a subset of patients can be cured with this approach...
  40. doi request reprint Clinicopathological characteristics of adamantinomatous and papillary craniopharyngiomas: University of California, San Francisco experience 1985-2005
    Melike Pekmezci
    Department of Pathology, University of California, San Francisco, San Francisco, California, USA
    Neurosurgery 67:1341-9; discussion 1349. 2010
    ..Craniopharyngiomas are rare epithelial tumors that are presumed to arise from the remnants of Rathke's pouch...
  41. doi request reprint Expression of p75NTR in fetal brain and medulloblastomas: evidence of a precursor cell marker and its persistence in neoplasia
    Michael Barnes
    Department of Pathology, UCSF Medical Center, San Francisco, CA, USA
    J Neurooncol 92:193-201. 2009
    ..The persistence of p75NTR in a small group of medulloblastomas raises the possibility that in such tumors, the receptor could be a potential therapeutic target...
  42. doi request reprint Secondary gliosarcoma: a review of clinical features and pathological diagnosis
    Seunggu J Han
    Department of Neurological Surgery, University of California, San Francisco, California 94117, USA
    J Neurosurg 112:26-32. 2010
    ..In this article the authors review the literature on secondary gliosarcoma, with attention to clinical course and pathological features...
  43. pmc Variants in the CDKN2B and RTEL1 regions are associated with high-grade glioma susceptibility
    Margaret Wrensch
    Department of Neurological Surgery, University of California, San Francisco, San Francisco, California, USA
    Nat Genet 41:905-8. 2009
    ..85 x 10(-10). On 20q13.3, rs6010620 intronic to RTEL1 had discovery P = 1.5 x 10(-7), replication P = 0.00035 and combined P = 3.40 x 10(-9). For both SNPs, the direction of association was the same in discovery and replication phases...
  44. doi request reprint Predictors of seizure freedom after surgery for malformations of cortical development
    Edward F Chang
    Northern California Comprehensive Epilepsy Center, San Francisco, San Francisco, CA 94143, USA
    Ann Neurol 70:151-62. 2011
    ..Our aim was to examine a surgical series of patients with cortical malformations to determine the prognostic factors associated with long-term seizure control...
  45. ncbi request reprint Loss of tumor suppressor PTEN function increases B7-H1 expression and immunoresistance in glioma
    Andrew T Parsa
    Department of Neurological Surgery, University of California San Francisco, 505 Parnassus Avenue, M 779, San Francisco, California 94143, USA
    Nat Med 13:84-8. 2007
    ..These data identify a previously unrecognized mechanism linking loss of the tumor suppressor PTEN with immunoresistance, mediated in part by B7-H1...
  46. pmc Reduced mural cell coverage and impaired vessel integrity after angiogenic stimulation in the Alk1-deficient brain
    Wanqiu Chen
    Department of Anesthesia and Perioperative Care, Center for Cerebrovascular Research, University of California, San Francisco, CA 94110, USA
    Arterioscler Thromb Vasc Biol 33:305-10. 2013
    ..We tested the hypothesis that vascular endothelial growth factor impairs vascular integrity in the Alk1-deficient brain through reduction of mural cell coverage...
  47. doi request reprint HIV TAT peptide modifies the distribution of DNA nanolipoparticles following convection-enhanced delivery
    J Andrew MacKay
    Joint Graduate Group in Bioengineering, University of California at San Francisco, San Francisco, California, USA
    Mol Ther 16:893-900. 2008
    ....
  48. doi request reprint Temporal fossa hemangiopericytoma: a case series
    Marc A Heiser
    Department of Otolaryngology Head and Neck Surgery, University of California at San Francisco, San Francisco, California 94143 0342, USA
    Otol Neurotol 30:985-9. 2009
    ..Review clinical experience with temporal fossa hemangiopericytomas (HPCs)...
  49. doi request reprint The molecular pathology of central neurocytomas
    Ari J Kane
    Department of Neurological Surgery, University of California at San Francisco, 505 Parnassus Avenue, San Francisco, California 94143, USA
    J Clin Neurosci 18:1-6. 2011
    ..Our discussion is expanded to include important and related insights into the cellular origin and classification of central nervous system tumors...
  50. ncbi request reprint Prognostic value of detecting recurrent glioblastoma multiforme in surgical specimens from patients after radiotherapy: should pathology evaluation alter treatment decisions?
    Tarik Tihan
    Department of Pathology, University of California at San Francisco, San Francisco, CA 94143 0511, USA
    Hum Pathol 37:272-82. 2006
    ..A comprehensive prospective study with advanced radiologic, pathologic, and molecular analyses may be more useful to determine prognostically valuable parameters...
  51. ncbi request reprint Intracranial dermoid cyst mimicking hemorrhage. Case report and review of the literature
    Rene O Sanchez-Mejia
    Department of Neurological Surgery, University of California, San Francisco 94143, USA
    J Neurosurg 105:311-4. 2006
    ..The authors describe their experience and review the literature, emphasizing that a dermoid cyst may have unusual radiographic characteristics indicative of hemorrhage and may contain areas of hemorrhage on histological examination...
  52. doi request reprint Inflammatory myofibroblastic tumor of the central nervous system and its relationship to inflammatory pseudotumor
    Rebecca S Swain
    Department of Pathology, Neuropathology, University of California, San Francisco, CA 94143 0102, USA
    Hum Pathol 39:410-9. 2008
    ..Neither IMT nor IP cases demonstrated HHV-8 expression. We suggest that IMT in the CNS is distinct from the nonneoplastic IP, and distinguishing IMT from nonneoplastic lesions should enable better decisions for patient management...
  53. pmc Pituicytoma: characterization of a unique neoplasm by histology, immunohistochemistry, ultrastructure, and array-based comparative genomic hybridization
    Joanna J Phillips
    Neuropathology Unit, University of California San Francisco, 505 Parnassus Avenue, San Francisco, CA 94143 0102, USA
    Arch Pathol Lab Med 134:1063-9. 2010
    ..This pattern of genetic changes only partially overlaps with the genomic alterations reported in pituitary adenomas. In summary, our data suggest that pituicytomas are a unique subset of tumors of the sellar region...
  54. doi request reprint Pathway analysis of single-nucleotide polymorphisms potentially associated with glioblastoma multiforme susceptibility using random forests
    Jeffrey S Chang
    Department of Epidemiology and Biostatistics, University of California, San Francisco, 44 Page Street, Suite 503, San Francisco, CA 94143 1215, USA
    Cancer Epidemiol Biomarkers Prev 17:1368-73. 2008
    ..Despite less than complete inclusion of genes and SNPs relevant to glioma and a small sample size, RF analysis identified one important biological pathway and several SNPs potentially associated with the development of glioblastoma...
  55. doi request reprint Pathology of spinal ependymomas: an institutional experience over 25 years in 134 patients
    Phiroz E Tarapore
    Department of Neurosurgery, University of California, San Francisco, San Francisco, California Department of Pathology, University of California, San Francisco, San Francisco, California
    Neurosurgery 73:247-55; discussion 255. 2013
    ..Ependymomas constitute approximately 40% of primary intraspinal tumors. Current World Health Organization (WHO) grading may not correlate with observed progression-free survival (PFS)...
  56. doi request reprint Falcine and parasagittal chondrosarcomas
    Michael Safaee
    Department of Neurological Surgery, University of California, San Francisco, 505 Parnassus Ave, Room 779M, San Francisco, CA 94143 0112, USA
    J Clin Neurosci 20:1232-6. 2013
    ..Treatment should be tailored to the biology of the tumor, with radiation therapy reserved for patients with the mesenchymal subtype. ..
  57. pmc Choroid plexus papillomas: advances in molecular biology and understanding of tumorigenesis
    Michael Safaee
    Department of Neurological Surgery, University of California at San Francisco, 505 Parnassus Ave, San Francisco, CA 94117, USA
    Neuro Oncol 15:255-67. 2013
    ..Improving our understanding of the molecular biology, genetics, and oncogenic pathways associated with this tumor will allow for the development of targeted therapies and improved outcomes for patients with this disease...
  58. doi request reprint Sarcoma arising as a distinct nodule within glioblastoma: a morphological and molecular perspective on gliosarcoma
    Cynthia Jimenez
    Department of Pathology, Neuropathology Unit, University of California at San Francisco, 505 Parnassus Avenue, San Francisco, CA 94143 0102, USA
    J Neurooncol 105:317-23. 2011
    ..Studies are under way to determine the significance of chromosome 3 alterations in gliosarcomas...
  59. ncbi request reprint Solitary fibrous tumors in the central nervous system. A clinicopathologic review of 18 cases and comparison to meningeal hemangiopericytomas
    Tarik Tihan
    Department of Pathology, The Johns Hopkins University School of Medicine, Baltimore, MD, USA
    Arch Pathol Lab Med 127:432-9. 2003
    ..In particular, densely cellular regions seen in some SFTs can be indistinguishable from HPC. Little is known about the biological behavior of SFTs, although most seem amenable to total resection...
  60. ncbi request reprint Solitary fibrous tumor arising from Cranial Nerve VI in the prepontine cistern: case report and review of a tumor subpopulation mimicking schwannoma
    James S Waldron
    Department of Neurological Surgery, University of California, San Francisco, San Francisco, California, USA
    Neurosurgery 59:E939-40; discussion E940. 2006
    ..In this study, the authors define a subpopulation of SFTs that seem to arise directly from nerve, rather than meninges, and clinically mimic the appearance of a schwannoma...
  61. ncbi request reprint Genetic aberrations in gliomatosis cerebri
    Marcus L Ware
    Department of Neurological Surgery, University of California, San Francisco, San Francisco, California, USA
    Neurosurgery 60:150-8; discussion 158. 2007
    ....
  62. doi request reprint Seizure control outcomes after resection of dysembryoplastic neuroepithelial tumor in 50 patients
    Edward F Chang
    Northern California Comprehensive Epilepsy Center, Brain Tumor Research Center, Department of Neurological Surgery, University of California, San Francisco, California 94143, USA
    J Neurosurg Pediatr 5:123-30. 2010
    ..The authors' aim was to identify factors that predict seizure control following excision...
  63. doi request reprint Intradural extramedullary leptomeningeal hemangioblastomatosis and paraneoplastic limbic encephalitis diagnosed at autopsy: an unlikely pair
    Rageshree Ramachandran
    Department of Pathology, University of California at San Francisco School of Medicine, San Francisco, CA, USA
    Arch Pathol Lab Med 132:104-8. 2008
    ..To the best of our knowledge, this is the first case of limbic encephalitis occurring in the setting of disseminated hemangioblastomatosis...
  64. ncbi request reprint Definition and diagnostic implications of gemistocytic astrocytomas: a pathological perspective
    Tarik Tihan
    Department of Pathology, UCSF School of Medicine, San Francisco, CA 94143 0511, USA
    J Neurooncol 76:175-83. 2006
    ..This article presents a critical review of the existing studies and a brief mention of our experience from a pathological perspective...
  65. ncbi request reprint Epidermal growth factor receptor, protein kinase B/Akt, and glioma response to erlotinib
    Daphne A Haas-Kogan
    Department of Neurosurgery, Brain Tumor Research Center, University of California San Francisco, 1600 Divisadero Street, Suite H1031, San Francisco, CA 94143, USA
    J Natl Cancer Inst 97:880-7. 2005
    ....
  66. ncbi request reprint Current treatment strategies and outcomes in the management of symptomatic vertebral hemangiomas
    Frank L Acosta
    Department of Neurological Surgery, University of California, San Francisco 94143 0112, USA
    Neurosurgery 58:287-95; discussion 287-95. 2006
    ..Treatment included transarterial embolization, embolization followed by surgical decompression or vertebral reconstruction with arthrodesis, and percutaneous vertebroplasty alone...
  67. doi request reprint Cardiac rupture after intravenous t-PA administration in acute ischemic stroke
    Amar Dhand
    Department of Neurology, University of California San Francisco, 505 Parnassus Avenue, Box 0114, San Francisco, CA 94143 0114, USA
    Neurocrit Care 13:261-2. 2010
    ..Although described in MI patients who receive thrombolytic therapy, this complication is not well known in ischemic stroke patients who receive intravenous (IV) t-PA...
  68. doi request reprint Clinical management of pituitary carcinomas
    Michael C Oh
    Department of Neurological Surgery, California Center for Pituitary Disorders, University of California, San Francisco, San Francisco, CA 94143, USA
    Neurosurg Clin N Am 23:595-606. 2012
    ..Here we review the clinical behavior and pathologic characteristics of pituitary carcinomas and the recent advances in potential therapies for this malignant disease...
  69. pmc Silent intralesional microhemorrhage as a risk factor for brain arteriovenous malformation rupture
    Yi Guo
    University of California, San Francisco, CA 94110, USA
    Stroke 43:1240-6. 2012
    ....
  70. ncbi request reprint Management of a sporadic malignant subfrontal peripheral nerve sheath tumor
    Rene O Sanchez-Mejia
    Department of Neurological Surgery, University of California, M 779, Box 0112, San Francisco, CA 94143, USA
    J Neurooncol 76:165-9. 2006
    ..Our case shows that these rare lesions can present as a malignant variant and thus require aggressive surgical and postoperative management to provide long-term tumor control...
  71. pmc A case of enteroviral meningoencephalitis presenting as rapidly progressive dementia
    Victor Valcour
    Department of Neurology, Memory and Aging Center, University of California, San Francisco, CA94143, USA
    Nat Clin Pract Neurol 4:399-403. 2008
    ..He had hypophonic speech and had mildly increased axial tone. He scored 5 out of 30 on the Mini Mental State Examination and was admitted for expedited evaluation...
  72. pmc Primary gliosarcoma: key clinical and pathologic distinctions from glioblastoma with implications as a unique oncologic entity
    Seunggu J Han
    Department of Neurological Surgery, University of California at San Francisco, 505 Parnassus Ave, San Francisco, CA 94117, USA
    J Neurooncol 96:313-20. 2010
    ..Clinical and pathologic characteristics distinct from GBM suggest that they may warrant specific treatment, separate from conventional GBM therapy...
  73. doi request reprint Radiobiology of vestibular schwannomas: mechanisms of radioresistance and potential targets for therapeutic sensitization
    Andrea H Yeung
    Departments of Otolaryngology Head and Neck Surgery, University of California at San Francisco, San Francisco, California, USA
    Neurosurg Focus 27:E2. 2009
    ..An improved understanding of the radiobiological behavior of VS may help guide appropriate patient selection for SRS and potentially aid in the design of novel therapies to treat radioresistant tumors...
  74. ncbi request reprint The pilomyxoid astrocytoma and its relationship to pilocytic astrocytoma: report of a case and a critical review of the entity
    Eugene P Ceppa
    Department of Pathology, University of California, Neuropathology Unit, 513 Parnassus Avenue, HSW 408 Box 0511, San Francisco, CA 94143 0511, USA
    J Neurooncol 81:191-6. 2007
    ..More systematic review of such cases will provide a better answer for the origin of PMA, and its relation to PA...
  75. ncbi request reprint The value of tandem CSF/MRI evaluation for predicting disseminated disease in childhood central nervous system neoplasms
    Judy Pang
    Department of Pathology, UCSF School of Medicine, San Francisco, CA, 94143 0102, USA
    J Neurooncol 87:97-102. 2008
    ..Even though the number of cases is limited, our findings suggest that a positive CSF cytology with no other corroborating evidence of tumor spread or recurrence should be interpreted with caution...
  76. ncbi request reprint Medulloblastomas with systemic metastases: evaluation of tumor histopathology and clinical behavior in 23 patients
    Charles G Eberhart
    Department of Pathology, Johns Hopkins University School of Medicine, Baltimore, Maryland 21287, USA
    J Pediatr Hematol Oncol 25:198-203. 2003
    ..To review the clinical behavior and histopathologic features of medulloblastomas that metastasize outside the central nervous systems (CNS)...
  77. ncbi request reprint Epidemiology and pathology of intraventricular tumors
    James S Waldron
    Department of Neurological Surgery, University of California at San Francisco, 513 Parnassus, HSW 511, San Francisco, CA 94143 0511, USA
    Neurosurg Clin N Am 14:469-82. 2003
    ..When used in conjunction with clinical and radiologic data, histopathologic features can distinguish among this wide range of possibilities to provide the correct diagnosis for optimal patient management...
  78. ncbi request reprint Retro-convection enhanced delivery to increase blood to brain transfer of macromolecules
    Grace H Huynh
    Joint Graduate Group in Bioengineering, University of California, San Francisco and University of California, Berkeley, San Francisco, CA 94143 0446, USA
    Brain Res 1128:181-90. 2007
    ....
  79. ncbi request reprint Differentiation of low-grade oligodendrogliomas from low-grade astrocytomas by using quantitative blood-volume measurements derived from dynamic susceptibility contrast-enhanced MR imaging
    Soonmee Cha
    Department of Radiology, University of California San Francisco, UCSF Medical Center, 505 Parnassus Avenue, San Francisco, CA 94143 0628, USA
    AJNR Am J Neuroradiol 26:266-73. 2005
    ..We hypothesized that tumor blood-volume measurements, derived from DSC MR imaging, would help differentiate the two on the basis of differences in tumor vascularity...
  80. ncbi request reprint Myxopapillary ependymoma: cytomorphologic characteristics and differential diagnosis
    Peter Kulesza
    The John K Frost Cytopathology Laboratory, Department of Pathology, The Johns Hopkins Hospital, Baltimore, Maryland 21287, USA
    Diagn Cytopathol 26:247-50. 2002
    ..An accurate preoperative diagnosis of ME on FNA can be achieved based on its distinctive cytomorphologic features...
  81. ncbi request reprint Lhermitte-Duclos disease: a report of 31 cases with immunohistochemical analysis of the PTEN/AKT/mTOR pathway
    Ty W Abel
    Department of Pathology, Division of Neuropathology, Johns Hopkins University, Baltimore, Maryland 21287, USA
    J Neuropathol Exp Neurol 64:341-9. 2005
    ..These data support recommendations for genetic testing and screening for CD in patients with LDD and suggest a novel therapy for LDD through pharmacologic inhibition of mTOR...
  82. ncbi request reprint The hypoxic response of tumors is dependent on their microenvironment
    Barbara Blouw
    Molecular Biology Section, Division of Biological Sciences, University of California at San Diego, Pacific Hall Room 1212, MC 0366, 9500 Gilman Drive, La Jolla, CA 92093, USA
    Cancer Cell 4:133-46. 2003
    ..These results demonstrate that HIF-1alpha has differential roles in tumor progression, which are greatly dependent on the extant microenvironment of the tumor...
  83. ncbi request reprint Combination chemotherapy of BCNU and Didox acts synergystically in 9L glioma cells
    Zsuzsanna Horvath
    Clinical Institute of Medical and Chemical Laboratory Diagnostics, University of Vienna, Vienna, Austria
    Nucleosides Nucleotides Nucleic Acids 23:1531-5. 2004
    ..These results introduce the combination of Didox and BCNU as a viable alternative for the treatment of malignant gliomas...
  84. ncbi request reprint Desmoplastic noninfantile ganglioglioma: report of a case
    Ibrahim Qaddoumi
    Department of Oncology, King Hussein Cancer Center, Amman, Jordan
    Pediatr Dev Pathol 9:462-7. 2006
    ..It is also unclear whether the desmoplastic noninfantile ganglioglioma has characteristics similar to classical ganglioglioma. This rare case highlights the remarkable versatility of glioneuronal tumors in children...
  85. ncbi request reprint Newly codified glial neoplasms of the 2007 WHO Classification of Tumours of the Central Nervous System: angiocentric glioma, pilomyxoid astrocytoma and pituicytoma
    Daniel J Brat
    Department of Pathology and Laboratory Medicine, 1364 Clifton Road NE, Atlanta, GA 30322, USA
    Brain Pathol 17:319-24. 2007
    ..It is solid in architecture, composed of spindle cells and presumably derived from pituicytes. Pituicytomas are indolent tumours, and are designated WHO grade I...
  86. ncbi request reprint Monomorphous angiocentric glioma: a distinctive epileptogenic neoplasm with features of infiltrating astrocytoma and ependymoma
    Min Wang
    Department of Pathology and Laboratory Medicine, University of Texas Health Science Center at Houston, Medical School, Houston, Texas, USA
    J Neuropathol Exp Neurol 64:875-81. 2005
    ..Overall, the tumors were biologically indolent except for one that recurred and ultimately proved fatal...
  87. ncbi request reprint Pilocytic and pilomyxoid hypothalamic/chiasmatic astrocytomas
    Ricardo J Komotar
    Department of Neurosurgery, Columbia University College of Physicians and Surgeons, New York, New York, USA
    Neurosurgery 54:72-9; discussion 79-80. 2004
    ..This article describes the clinicopathological features of these unusual neoplasms, which are currently known as pilomyxoid astrocytomas (PMAs), to better differentiate them from typical PAs...
  88. ncbi request reprint Polilactofate microspheres for Paclitaxel delivery to central nervous system malignancies
    Khan W Li
    Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland 21205, USA
    Clin Cancer Res 9:3441-7. 2003
    ....
  89. ncbi request reprint MR imaging characteristics of pilomyxoid astrocytomas
    Atilla Arslanoglu
    Department of Radiology, Johns Hopkins University, Baltimore, MD 21287, USA
    AJNR Am J Neuroradiol 24:1906-8. 2003
    ..These tumors have been previously diagnosed as pilocytic astrocytoma (PA). PMA appears to have a higher rate of recurrence and CSF dissemination than typical PA...
  90. ncbi request reprint Gene expression profiling reveals unique molecular subtypes of Neurofibromatosis Type I-associated and sporadic malignant peripheral nerve sheath tumors
    Mark A Watson
    Department of Pathology and Immunology, Washington University School of Medicine, St Louis, MO 63110, USA
    Brain Pathol 14:297-303. 2004
    ..We conclude that distinct molecular classes of MPNST exist and that the ability to stratify these tumors based on unique and biologically relevant gene expression profiles may be important for future targeted therapeutics...
  91. ncbi request reprint Synergistic cytotoxicity of the ribonucleotide reductase inhibitor didox (3,4-dihydroxy-benzohydroxamic acid) and the alkylating agent carmustine (BCNU) in 9L rat gliosarcoma cells and DAOY human medulloblastoma cells
    Zsuzsanna Horvath
    General Hospital of Vienna, Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Vienna, 5H Waehringer Guertel 18 20, 1090, Austria
    Cancer Chemother Pharmacol 54:139-45. 2004
    ....
  92. ncbi request reprint Recurrent glioependymal cyst of the posterior fossa: an unusual entity containing mixed glial elements. Case report
    James Frazier
    Department of Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, MD 21287, USA
    J Neurooncol 68:13-7. 2004
    ..Definitive diagnosis is by microscopic examination of surgically resected specimens. Total extirpation of these cystic lesions is recommended...
  93. ncbi request reprint Pilomyxoid astrocytoma of the spinal cord: report of three cases
    Ricardo J Komotar
    Department of Neurosurgery, Columbia University, New York, New York, USA
    Neurosurgery 56:191. 2005
    ..All PMAs reported to date involved the hypothalamic/chiasmatic region. Since these original reports, we have encountered three tumors in the spinal cord with histological features identical to those of PMA...
  94. pmc Pilomyxoid astrocytoma: a review
    Ricardo J Komotar
    Department of Neurosurgery, Columbia University, New York, USA
    MedGenMed 6:42. 2004
    ..Increased recognition of PMA within the medical community has the potential to affect the treatment and prognosis of pediatric low-grade astrocytomas...
  95. ncbi request reprint Pilomyxoid astrocytoma: diagnosis, prognosis, and management
    Ricardo J Komotar
    Department of Neurosurgery, Columbia University, New York, New York, USA
    Neurosurg Focus 18:E7. 2005
    ..To increase awareness of PMA within the neurosurgical community, the authors review the diagnostic criteria, prognostic implications, and current management of this recently described pediatric low-grade astrocytoma...
  96. ncbi request reprint Solitary central nervous system metastasis from acinic cell carcinoma of the parotid gland
    Maciej S Lesniak
    Department of Neurosurgery, The Johns Hopkins Hospital, Baltimore, Maryland 21287, USA
    J Otolaryngol 31:38-41. 2002
  97. ncbi request reprint Impact of telemedicine on pediatric neuro-oncology in a developing country: the Jordanian-Canadian experience
    Ibrahim Qaddoumi
    Department of Pediatrics, King Hussein Cancer Center KHCC, Amman, Jordan
    Pediatr Blood Cancer 48:39-43. 2007
    ..Pediatric neuro-oncology is a complex multidisciplinary discipline that is underserved in most of DC and provides a model to test the feasibility of such tool for twinning purposes...
  98. ncbi request reprint Growth and regression of arteriovenous malformations in a patient with hereditary hemorrhagic telangiectasia. Case report
    Rose Du
    Department of Neurological Surgery, Brigham and Women s Hospital, Harvard Medical School, Boston, Massachusetts, USA
    J Neurosurg 106:470-7. 2007
    ..Histopathological features of the surgical specimen were examined. Active angiogenesis, as indicated by increased endothelial proliferation, might be a part of the underlying pathophysiology of the growth and regression of AVMs...
  99. doi request reprint Issues of diagnostic review in brain tumor studies: from the Brain Tumor Epidemiology Consortium
    Faith G Davis
    Division of Epidemiology Biostatistics, School of Public Health, University of Illinois at Chicago, Chicago, IL 60612, USA
    Cancer Epidemiol Biomarkers Prev 17:484-9. 2008
    ..It is essential that epidemiologists and neuropathologists collaborate to develop appropriate study designs and protocols for specific hypothesis and populations...
  100. doi request reprint Outcome analysis of childhood low-grade astrocytomas
    Paul G Fisher
    Department of Neurology, Stanford University, Palo Alto, California 94305 5826, USA
    Pediatr Blood Cancer 51:245-50. 2008
    ..We aimed to determine the long-term natural history of low-grade astrocytomas (LGA) in children, with respect to pathology, and to evaluate influence of treatment on survival...
  101. pmc Brain tumor epidemiology: consensus from the Brain Tumor Epidemiology Consortium
    Melissa L Bondy
    Department of Epidemiology, The University of Texas M D Anderson Cancer Center, Houston, Texas 77030, USA
    Cancer 113:1953-68. 2008
    ..In this report, BTEC epidemiologists reviewed the group's consensus on the current state of scientific findings, and they present a consensus on research priorities to identify which important areas the science should move to address...