Research Topics
Species | E Gretchen TietjenSummaryAffiliation: University of Toledo Country: USA Publications
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Detail Information
Publications
Adverse childhood experiences are associated with migraine and vascular biomarkersGretchen E Tietjen
Department of Neurology, University of Toledo, 3000 Arlington Avenue, Toledo, OH 43614, USA
Headache 52:920-9. 2012..Our objective is to evaluate the relationship between adverse childhood experiences (ACEs), migraine, and vascular biomarker levels in premenopausal women...
Migraine genes and the relation to genderReinald Shyti
Department of Human Genetics, Leiden University Medical Centre, Leiden, The Netherlands
Headache 51:880-90. 2011..By deciphering genetic and pathogenic migraine pathways, it can be expected that in the near future we will better understand mechanisms behind the female preponderance in migraine...
Childhood abuse and migraine: epidemiology, sex differences, and potential mechanismsGretchen E Tietjen
Department of Neurology, University of Toledo, Toledo, OH, USA
Headache 51:869-79. 2011..Advances in our understanding of the basic mechanisms by which an adverse environment interacts with and changes the genome, may suggest new treatment strategies...
Platelet dysfunction and stroke in the female migraineurGretchen E Tietjen
Department of Neurology, The University of Toledo, 3000 Arlington Avenue, MS 1195, Toledo, OH 43614, USA
Curr Pain Headache Rep 13:386-91. 2009..Identifying those migraineurs at highest risk of developing endothelial dysfunction and platelet disorders may allow for preventive strategies to avoid the cerebral consequences...
Migraine and biomarkers of endothelial activation in young womenGretchen E Tietjen
Department of Neurology, University of Toledo College of Medicine, Toledo, OH 43614, USA
Stroke 40:2977-82. 2009..There is mounting evidence of endothelial activation and dysfunction in migraine. Our objectives were to determine in a population of premenopausal women whether endothelial activation markers are associated with migraine...
Association of von Willebrand factor activity with ACE I/D and MTHFR C677T polymorphisms in migraineG E Tietjen
Department of Neurology, The University of Toledo College of Medicine, Toledo, OH 43614, USA
Cephalalgia 29:960-8. 2009..ACE DD was associated with higher headache frequency, and MTHFR TT was associated with MA. In migraine, vWF activity may be a marker of endothelial-mediated genetic risk for ischaemic conditions...
History of childhood maltreatment is associated with comorbid depression in women with migraineG E Tietjen
Department of Neurology, College of Medicine, The University of Toledo Health Science Campus, Toledo, OH 43614, USA
Neurology 69:959-68. 2007..Our objective is to determine, within a headache clinic population of women, if depression moderates the abuse-migraine relationship...
Migraine and ischaemic heart disease and stroke: potential mechanisms and treatment implicationsE Gretchen Tietjen
Department of Neurology, The University of Toledo Health Science Campus, Toledo, OH 43614, USA
Cephalalgia 27:981-7. 2007..Although triptans are generally considered safe for use in migraine, caution is warranted in those with multiple vascular risk factors. Known vascular disease is a contraindication to triptan use...
Migraine as a systemic vasculopathyG E Tietjen
The University of Toledo, Department of Neurology, Toledo, OH 76508, USA
Cephalalgia 29:987-96. 2009..It is uncertain whether stroke, myocardial infarction and other vasculopathies can be prevented by migraine prophylaxis, endothelial repair, platelet inhibition or a combination of these strategies...
Altered hemostasis in migraineurs studied with a dynamic flow systemGretchen E Tietjen
Department of Neurology, Medical University of Ohio, Toledo, OH 43614, USA
Thromb Res 119:217-22. 2007..The purpose of this study is to evaluate global hemostasis in migraineurs, including the subset with LR, using a dynamic flow system simulating physiological conditions, and measuring vWF activity and antigen levels...
Plasma thrombosis markers following cerebral infarction in African AmericansAskiel Bruno
Department of Neurology, Indiana University School of Medicine, 541 Clinical Drive, Room 292, Indianapolis, IN 46202-5111, USA
Thromb Res 115:73-7. 2005
Livedo reticularis and migraine: a marker for stroke risk?Gretchen E Tietjen
Department of Neurology, Medical College of Ohio, Toledo, USA
Headache 42:352-5. 2002..Over 50% of persons with Sneddon syndrome describe a history of headache. We undertook this study to determine the frequency of livedo reticularis in our headache clinic...
High prevalence of somatic symptoms and depression in women with disabling chronic headacheG E Tietjen
Department of Neurology, The University of Toledo Health Science Campus, Toledo, OH 43614, USA
Neurology 68:134-40. 2007..To better define, in women with headache, the relationship of depression and somatic symptoms to headache, characterized by diagnoses, frequency, and disability...
Increased von Willebrand factor in migraineG E Tietjen
Department of Neurology, Medical College of Ohio, Toledo, USA
Neurology 57:334-6. 2001..vWF antigen (126%) and activity (130%) were also significantly higher in migraineurs without stroke. Multimers and protease activity were normal in the interictal subset...
