Research Topics
Species | Yingfang TianSummaryAffiliation: University of California Country: USA Publications
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Publications
Effects of gender on gene expression in the blood of ischemic stroke patientsYingfang Tian
Department of Neurology, The MIND Institute, University of California at Davis, Sacramento, CA, USA
J Cereb Blood Flow Metab 32:780-91. 2012..Gender affects gene expression in the blood of IS patients, which likely implies gender differences in immune, inflammatory, and cell death responses to stroke...- Y chromosome gene expression in the blood of male patients with ischemic stroke compared with male controlsYingfang Tian
Department of Neurology and the MIND Institute, University of California at Davis, Sacramento, California 95817, USA
Gend Med 9:68-75.e3. 2012.... - Exon expression and alternatively spliced genes in Tourette SyndromeYingfang Tian
M I N D Institute, Department of Neurology, University of California at Davis, Sacramento, 95817, USA
Am J Med Genet B Neuropsychiatr Genet 156:72-8. 2011..However, the findings are tempered by the small sample size and multiple comparisons and require confirmation using PCR or deep RNA sequencing and a much larger patient population... 
Differences in exon expression and alternatively spliced genes in blood of multiple sclerosis compared to healthy control subjectsYingfang Tian
Department of Neurology and MIND Institute, University of California at Davis, Sacramento, CA 95817, United States
J Neuroimmunol 230:124-9. 2011..However, given that multiple comparisons were performed on a very small sample, these preliminary findings require confirmation using a much larger independent cohort...- Correlations of gene expression with blood lead levels in children with autism compared to typically developing controlsYingfang Tian
Department of Neurology, University of California at Davis, Sacramento, CA 95817, USA
Neurotox Res 19:1-13. 2011..We postulate that this may relate to the underlying genetic differences between the two groups, though other explanations cannot be excluded... - The X-chromosome has a different pattern of gene expression in women compared with men with ischemic strokeBoryana Stamova
Departments of Neurology, University of California at Davis, MIND Institute and Department of Neurology, 2805 50th Street, Sacramento CA 95817, USA
Stroke 43:326-34. 2012..However, sex differences in immune response to ischemia may exist. We hypothesized that differential expression of X-chromosome genes in blood immune cells contribute to differences between men and women with ischemic stroke... - Gene expression profiling of blood for the prediction of ischemic strokeBoryana Stamova
Department of Neurology and the MIND Institute, University of California at Davis, Sacramento, Calif 95817, USA
Stroke 41:2171-7. 2010..This study aimed to (1) replicate in a larger cohort our previous study using gene expression profiling to predict ischemic stroke; and (2) refine prediction of ischemic stroke by including control groups relevant to ischemic stroke... - GABA- and acetylcholine-related gene expression in blood correlate with tic severity and microarray evidence for alternative splicing in Tourette syndrome: a pilot studyYingfang Tian
University of California at Davis, M I N D, Institute and Department of Neurology, USA
Brain Res 1381:228-36. 2011..This pilot study suggests that at least some of these GABA- and ACh-related genes observed in blood that correlate with tics or are alternatively spliced are involved in the pathophysiology of TS and tics... - Profiles of lacunar and nonlacunar strokeGlen C Jickling
Department of Neurology and the MIND Institute, University of California at Davis, Sacramento, CA 95817, USA
Ann Neurol 70:477-85. 2011..We sought to distinguish lacunar from nonlacunar causes of SDIs using a gene expression profile... - Correlations of gene expression with ratings of inattention and hyperactivity/impulsivity in Tourette syndrome: a pilot studyYingfang Tian
MIND Institute and Department of Neurology, University of California at Davis, Sacramento, CA 95817, USA
BMC Med Genomics 5:49. 2012..This study determined if gene expression in blood correlated significantly with IA and/or HI rating scale scores in participants with TS... - Ischemic transient neurological events identified by immune response to cerebral ischemiaGlen C Jickling
University of California at Davis, MIND Institute, 2805 50th Street, Sacramento, CA 95817, USA
Stroke 43:1006-12. 2012..Ischemia of cerebral tissue elicits an immune response in stroke and transient ischemic attack (TIA). This response, as detected by RNA expressed in immune cells, could potentially distinguish ischemic from nonischemic TNE... - Signatures of cardioembolic and large-vessel ischemic strokeGlen C Jickling
Department of Neurology and the MIND Institute, University of California at Davis, Sacramento, CA 95817, USA
Ann Neurol 68:681-92. 2010..We sought to determine whether gene expression signatures in blood can distinguish between cardioembolic and large-vessel causes of stroke, and whether these profiles can predict stroke etiology in the cryptogenic group... - Genome response to tissue plasminogen activator in experimental ischemic strokeGlen C Jickling
Department of Neurology and M, I, N, d, Institute, University of California at Davis, Sacramento, California 95817, USA
BMC Genomics 11:254. 2010..To further delineate tPA functions in the blood, we examined the gene expression profiles induced by tPA in a rat model of ischemic stroke... - RNA expression profiles from blood for the diagnosis of stroke and its causesFrank R Sharp
Department of Neurology, University of California at Davis, Sacramento, CA, USA
J Child Neurol 26:1131-6. 2011..These profiles will be useful for predicting the causes of cryptogenic stroke. The results in adults suggest that similar diagnostic tools could be developed for children... - Correlations between gene expression and mercury levels in blood of boys with and without autismBoryana Stamova
Department of Neurology, University of California at Davis Medical Center, Sacramento, CA 95817, USA
Neurotox Res 19:31-48. 2011..These findings might suggest different genetic transcriptional programs associated with mercury in AU compared to TD children... - Brain and blood microRNA expression profiling of ischemic stroke, intracerebral hemorrhage, and kainate seizuresDa Zhi Liu
Department of Neurology and the M I N D Institute, University of California at Davis Medical Center, Sacramento, California 95817, USA
J Cereb Blood Flow Metab 30:92-101. 2010.... - Integrated analysis of mRNA and microRNA expression in mature neurons, neural progenitor cells and neuroblastoma cellsDa Zhi Liu
Department of Neurology and the M I N D Institute, University of California at Davis, Sacramento, CA 95817, USA
Gene 495:120-7. 2012..g., miR-370, miR-9, miR-672) in NBCs are associated with cancer pathways. These results provide a library of negative mRNAmiRNA networks that are likely involved in the cellular processes of differentiation and division... - Molecular markers and mechanisms of stroke: RNA studies of blood in animals and humansFrank R Sharp
Department of Neurology, MIND Institute, University of California at Davis, Sacramento, California 95817, USA
J Cereb Blood Flow Metab 31:1513-31. 2011..New techniques to measure all coding and noncoding RNAs along with alternatively spliced transcripts will markedly advance molecular studies of human stroke... - Distinctive RNA expression profiles in blood associated with white matter hyperintensities in brainHuichun Xu
Department of Neurology and M I N D Institute, University of California at Davis, Sacramento, CA 95817, USA
Stroke 41:2744-9. 2010..Thus, RNA expression was assessed in the blood of individuals with and without extensive WMH to search for evidence of oxidative stress, inflammation, and other abnormalities described in WMH lesions in brain... - Genome wide differences of gene expression associated with HLA-DRB1 genotype in multiple sclerosis: A pilot studyMichelle L Apperson
Department of Neurology and the M I N D Institute, University of California at Davis, Sacramento, CA 95817, United States Department of Neurology, VA Northern California Health System, Mather, CA 95655, United States Electronic address
J Neuroimmunol 257:90-6. 2013..Different risk alleles appear to be associated with different patterns of gene expression that may reflect differences in pathophysiology of these two MS subtypes. These preliminary data will need to be confirmed in future studies... - Catecholamine-related gene expression in blood correlates with tic severity in tourette syndromeJoan Gunther
Department of Neurology and MIND Institute, University of California at Davis, 2805 50th Street, Sacramento, CA 95817, USA
Psychiatry Res 200:593-601. 2012..Findings built on previous work suggest that at least some genes expressed peripherally are relevant for central nervous system (CNS) pathology in the brain of individuals with TS... - Identification and validation of suitable endogenous reference genes for gene expression studies in human peripheral bloodBoryana S Stamova
Department of Neurology and M, Institute, University of California at Davis Medical Center, Sacramento, CA 95817, USA
BMC Med Genomics 2:49. 2009..These genes should be useful as normalization genes for microarray and RT-PCR whole blood studies of human physiology, metabolism and disease...