Research Topics
| SARAH W THURSTONSummaryAffiliation: University of Rochester Country: USA Publications
Research Grants
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Detail Information
Publications
Does prenatal methylmercury exposure from fish consumption affect blood pressure in childhood?Sally W Thurston
Department of Biostatistics and Computational Biology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, United States
Neurotoxicology 28:924-30. 2007..We examined this relationship in the Seychelles Islands to determine if it was present in a society exposed primarily to MeHg from consuming ocean fish...
Smoothing in survival models: an application to workers exposed to metalworking fluidsSally W Thurston
Department of Biostatistics, Harvard School of Mental Health, Boston, MA, USA
Epidemiology 13:685-92. 2002..CONCLUSIONS This example illustrates that the penalized spline methodology can be easily applied to cohort studies to estimate smooth exposure-response curves...- Bayesian models for multiple outcomes nested in domainsSally W Thurston
University of Rochester, Department of Biostatistics and Computational Biology, 601 Elmwood Avenue, Box 630, Rochester, New York 14642, USA
Biometrics 65:1078-86. 2009..Simulation studies examine the model performance under alternative scenarios. Our results demonstrate that a sizeable increase in power is possible... - Modeling lung cancer risk in case-control studies using a new dose metric of smokingSally W Thurston
Department of Biostatistics and Computational Biology, University of Rochester, 601 Elmwood Avenue, Rochester, NY 14642, USA
Cancer Epidemiol Biomarkers Prev 14:2296-302. 2005..In conclusion, we provide a general framework for evaluating different smoking metrics in studies where smoking is a critical variable... - Association between prenatal exposure to methylmercury and visuospatial ability at 10.7 years in the seychelles child development studyPhilip W Davidson
University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
Neurotoxicology 29:453-9. 2008..04), but not when the single outlier was removed (p=0.07). In a population whose exposure to MeHg is from fish consumption, we continue to find no consistent adverse association between MeHg and visual motor coordination... - One semen sample or 2? Insights from a study of fertile menAbbie Stokes-Riner
Department of Biostatistics and Computational Biology, University of Rochester Medical Center, 601 Elmwood Ave, Box 630, Rochester, NY 14642, USA
J Androl 28:638-43. 2007 - Neurodevelopmental effects of maternal nutritional status and exposure to methylmercury from eating fish during pregnancyPhilip W Davidson
University of Rochester School of Medicine and Dentistry, Box 671, URMC, 601 Elmwood Avenue, Rochester, NY 14642, USA
Neurotoxicology 29:767-75. 2008..These findings suggest a possible confounding role of maternal nutrition in studies examining associations between prenatal MeHg exposures and developmental outcomes in children... - Interpreting epidemiological evidence in the presence of multiple endpoints: an alternative analytic approach using the 9-year follow-up of the Seychelles child development studyEdwin van Wijngaarden
Department of Community and Preventive Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY, 14642, USA
Int Arch Occup Environ Health 82:1031-41. 2009..These studies evaluate a large number of developmental tests. We propose an alternative analysis strategy that reduces the number of comparisons tested in these studies... - Postnatal exposure to methyl mercury from fish consumption: a review and new data from the Seychelles Child Development StudyGary J Myers
University of Rochester School of Medicine and Dentistry, Department of Neurology, Rochester, NY, United States
Neurotoxicology 30:338-49. 2009.... - Is susceptibility to prenatal methylmercury exposure from fish consumption non-homogeneous? Tree-structured analysis for the Seychelles Child Development StudyLi Shan Huang
Department of Biostatistics and Computational Biology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
Neurotoxicology 28:1237-44. 2007..The regression tree results support previous analyses of outcomes in this cohort. However, this analysis raises the intriguing possibility that an effect may be non-homogeneous among children with different backgrounds and IQ levels... - Genetic polymorphisms in N-acetyltransferase-2 and microsomal epoxide hydrolase, cumulative cigarette smoking, and lung cancerWei Zhou
Occupational Health Program, Department of Environmental Health, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA
Cancer Epidemiol Biomarkers Prev 11:15-21. 2002..The joint effects of NAT2 and mEH polymorphisms are consistent with an independent, additive effect of these two genes, modified by smoking history... - Prenatal organochlorine exposure and behaviors associated with attention deficit hyperactivity disorder in school-aged childrenSharon K Sagiv
Department of Environmental Health, Harvard School of Public Health, Boston, MA 02115, USA
Am J Epidemiol 171:593-601. 2010..76, 95% confidence interval: 1.06, 2.92) and a similar relation for p,p'-DDE. These results support an association between low-level prenatal organochlorine exposure and ADHD-like behaviors in childhood... - On the use of biomarkers for environmental health researchLouise Ryan
Department of Biostatistics, Harvard School of Public Health, Boston, MA 02115, USA
Stat Methods Med Res 13:207-25. 2004.... - Organic and inorganic mercury in neonatal rat brain after prenatal exposure to methylmercury and mercury vaporHiromi Ishitobi
Department of Environmental Medicine, School of Medicine and Dentistry, University of Rochester, Rochester, New York 14642, USA
Environ Health Perspect 118:242-8. 2010..Most of our knowledge of the neurotoxicity of Hg is based on research devoted to studying only one form at a time, mostly MeHg... - Polymorphisms in the DNA repair genes XRCC1 and ERCC2, smoking, and lung cancer riskWei Zhou
Occupational Health Program, Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts 02115, USA
Cancer Epidemiol Biomarkers Prev 12:359-65. 2003..In conclusion, cumulative cigarette smoking plays an important role in altering the direction and magnitude of the associations between the XRCC1 and ERCC2 polymorphisms and lung cancer risk... - Are environmental levels of bisphenol a associated with reproductive function in fertile men?Jaime Mendiola
Department of Obstetrics and Gynecology, School of Medicine and Dentistry, University of Rochester, Rochester, New York, USA
Environ Health Perspect 118:1286-91. 2010..Rodent and in vitro studies have demonstrated the estrogenicity of bisphenol A (BPA). However, few studies have examined the relationship between human exposure to BPA and male reproductive function... - Gene-environment interaction for the ERCC2 polymorphisms and cumulative cigarette smoking exposure in lung cancerWei Zhou
Occupational Health Program, Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts 02115, USA
Cancer Res 62:1377-81. 2002..A stronger gene-smoking interaction was observed for the Asp312Asn polymorphism than for the Lys751Gln polymorphism. In conclusion, cumulative cigarette smoking modifies the associations between ERCC2 polymorphisms and lung cancer risk... - P53 (codon 72) and P21 (codon 31) polymorphisms alter in vivo mRNA expression of p21Li Su
Occupational Health Program, Department of Environmental Health, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA
Lung Cancer 40:259-66. 2003..Results were consistent in both patients with lung cancer (n=63) and in normal controls (n=21). In conclusion, the presence of a p53 Pro allele and/or p21 Arg allele is associated with lower downstream target gene expression of p21... - Early alterations in cytokine expression in adult compared to developing lung in mice after radiation exposureCarl J Johnston
Departments of Pediatrics and Neonatology, University of Rochester Medical Center, Rochester, New York 14642, USA
Radiat Res 173:522-35. 2010..They may be candidates for use in marker-based biodosimetry. However, the lack of cytokine induction in early life suggests that different end points (and mitigating treatments) may be required for children... - Mathematical modeling of ultradeep sequencing data reveals that acute CD8+ T-lymphocyte responses exert strong selective pressure in simian immunodeficiency virus-infected macaques but still fail to clear founder epitope sequencesTanzy M T Love
Department of Biostatistics and Computational Biology, University of Rochester, Rochester, New York 14642, USA
J Virol 84:5802-14. 2010..Our results suggest that a reservoir of SIV infection is preferentially formed by virus with the transmitted epitope... - Comparing smoothing techniques in Cox models for exposure-response relationshipsUsha S Govindarajulu
Yale Center for Clinical Investigation, Yale School of Medicine, New Haven, CT 06510, USA
Stat Med 26:3735-52. 2007..Overall, the penalized spline and the restricted cubic spline were closer to each other than either was to the fractional polynomial...
Research Grants
- BAYESIAN BIOMARKER MODELS FOR CANCER GENETICS STUDIESSARAH THURSTON; Fiscal Year: 2004..abstract_text> ..