SARAH W THURSTON

Summary

Affiliation: University of Rochester
Country: USA

Publications

  1. pmc Does prenatal methylmercury exposure from fish consumption affect blood pressure in childhood?
    Sally W Thurston
    Department of Biostatistics and Computational Biology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, United States
    Neurotoxicology 28:924-30. 2007
  2. ncbi request reprint Smoothing in survival models: an application to workers exposed to metalworking fluids
    Sally W Thurston
    Department of Biostatistics, Harvard School of Mental Health, Boston, MA, USA
    Epidemiology 13:685-92. 2002
  3. pmc Bayesian models for multiple outcomes nested in domains
    Sally W Thurston
    University of Rochester, Department of Biostatistics and Computational Biology, 601 Elmwood Avenue, Box 630, Rochester, New York 14642, USA
    Biometrics 65:1078-86. 2009
  4. pmc Modeling lung cancer risk in case-control studies using a new dose metric of smoking
    Sally W Thurston
    Department of Biostatistics and Computational Biology, University of Rochester, 601 Elmwood Avenue, Rochester, NY 14642, USA
    Cancer Epidemiol Biomarkers Prev 14:2296-302. 2005
  5. pmc Association between prenatal exposure to methylmercury and visuospatial ability at 10.7 years in the seychelles child development study
    Philip W Davidson
    University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Neurotoxicology 29:453-9. 2008
  6. ncbi request reprint One semen sample or 2? Insights from a study of fertile men
    Abbie Stokes-Riner
    Department of Biostatistics and Computational Biology, University of Rochester Medical Center, 601 Elmwood Ave, Box 630, Rochester, NY 14642, USA
    J Androl 28:638-43. 2007
  7. pmc Neurodevelopmental effects of maternal nutritional status and exposure to methylmercury from eating fish during pregnancy
    Philip W Davidson
    University of Rochester School of Medicine and Dentistry, Box 671, URMC, 601 Elmwood Avenue, Rochester, NY 14642, USA
    Neurotoxicology 29:767-75. 2008
  8. pmc Interpreting epidemiological evidence in the presence of multiple endpoints: an alternative analytic approach using the 9-year follow-up of the Seychelles child development study
    Edwin van Wijngaarden
    Department of Community and Preventive Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY, 14642, USA
    Int Arch Occup Environ Health 82:1031-41. 2009
  9. pmc Postnatal exposure to methyl mercury from fish consumption: a review and new data from the Seychelles Child Development Study
    Gary J Myers
    University of Rochester School of Medicine and Dentistry, Department of Neurology, Rochester, NY, United States
    Neurotoxicology 30:338-49. 2009
  10. pmc Is susceptibility to prenatal methylmercury exposure from fish consumption non-homogeneous? Tree-structured analysis for the Seychelles Child Development Study
    Li Shan Huang
    Department of Biostatistics and Computational Biology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Neurotoxicology 28:1237-44. 2007

Research Grants

Detail Information

Publications21

  1. pmc Does prenatal methylmercury exposure from fish consumption affect blood pressure in childhood?
    Sally W Thurston
    Department of Biostatistics and Computational Biology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, United States
    Neurotoxicology 28:924-30. 2007
    ..We examined this relationship in the Seychelles Islands to determine if it was present in a society exposed primarily to MeHg from consuming ocean fish...
  2. ncbi request reprint Smoothing in survival models: an application to workers exposed to metalworking fluids
    Sally W Thurston
    Department of Biostatistics, Harvard School of Mental Health, Boston, MA, USA
    Epidemiology 13:685-92. 2002
    ..CONCLUSIONS This example illustrates that the penalized spline methodology can be easily applied to cohort studies to estimate smooth exposure-response curves...
  3. pmc Bayesian models for multiple outcomes nested in domains
    Sally W Thurston
    University of Rochester, Department of Biostatistics and Computational Biology, 601 Elmwood Avenue, Box 630, Rochester, New York 14642, USA
    Biometrics 65:1078-86. 2009
    ..Simulation studies examine the model performance under alternative scenarios. Our results demonstrate that a sizeable increase in power is possible...
  4. pmc Modeling lung cancer risk in case-control studies using a new dose metric of smoking
    Sally W Thurston
    Department of Biostatistics and Computational Biology, University of Rochester, 601 Elmwood Avenue, Rochester, NY 14642, USA
    Cancer Epidemiol Biomarkers Prev 14:2296-302. 2005
    ..In conclusion, we provide a general framework for evaluating different smoking metrics in studies where smoking is a critical variable...
  5. pmc Association between prenatal exposure to methylmercury and visuospatial ability at 10.7 years in the seychelles child development study
    Philip W Davidson
    University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Neurotoxicology 29:453-9. 2008
    ..04), but not when the single outlier was removed (p=0.07). In a population whose exposure to MeHg is from fish consumption, we continue to find no consistent adverse association between MeHg and visual motor coordination...
  6. ncbi request reprint One semen sample or 2? Insights from a study of fertile men
    Abbie Stokes-Riner
    Department of Biostatistics and Computational Biology, University of Rochester Medical Center, 601 Elmwood Ave, Box 630, Rochester, NY 14642, USA
    J Androl 28:638-43. 2007
  7. pmc Neurodevelopmental effects of maternal nutritional status and exposure to methylmercury from eating fish during pregnancy
    Philip W Davidson
    University of Rochester School of Medicine and Dentistry, Box 671, URMC, 601 Elmwood Avenue, Rochester, NY 14642, USA
    Neurotoxicology 29:767-75. 2008
    ..These findings suggest a possible confounding role of maternal nutrition in studies examining associations between prenatal MeHg exposures and developmental outcomes in children...
  8. pmc Interpreting epidemiological evidence in the presence of multiple endpoints: an alternative analytic approach using the 9-year follow-up of the Seychelles child development study
    Edwin van Wijngaarden
    Department of Community and Preventive Medicine, University of Rochester School of Medicine and Dentistry, Rochester, NY, 14642, USA
    Int Arch Occup Environ Health 82:1031-41. 2009
    ..These studies evaluate a large number of developmental tests. We propose an alternative analysis strategy that reduces the number of comparisons tested in these studies...
  9. pmc Postnatal exposure to methyl mercury from fish consumption: a review and new data from the Seychelles Child Development Study
    Gary J Myers
    University of Rochester School of Medicine and Dentistry, Department of Neurology, Rochester, NY, United States
    Neurotoxicology 30:338-49. 2009
    ....
  10. pmc Is susceptibility to prenatal methylmercury exposure from fish consumption non-homogeneous? Tree-structured analysis for the Seychelles Child Development Study
    Li Shan Huang
    Department of Biostatistics and Computational Biology, University of Rochester School of Medicine and Dentistry, Rochester, NY 14642, USA
    Neurotoxicology 28:1237-44. 2007
    ..The regression tree results support previous analyses of outcomes in this cohort. However, this analysis raises the intriguing possibility that an effect may be non-homogeneous among children with different backgrounds and IQ levels...
  11. ncbi request reprint Genetic polymorphisms in N-acetyltransferase-2 and microsomal epoxide hydrolase, cumulative cigarette smoking, and lung cancer
    Wei Zhou
    Occupational Health Program, Department of Environmental Health, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA
    Cancer Epidemiol Biomarkers Prev 11:15-21. 2002
    ..The joint effects of NAT2 and mEH polymorphisms are consistent with an independent, additive effect of these two genes, modified by smoking history...
  12. pmc Prenatal organochlorine exposure and behaviors associated with attention deficit hyperactivity disorder in school-aged children
    Sharon K Sagiv
    Department of Environmental Health, Harvard School of Public Health, Boston, MA 02115, USA
    Am J Epidemiol 171:593-601. 2010
    ..76, 95% confidence interval: 1.06, 2.92) and a similar relation for p,p'-DDE. These results support an association between low-level prenatal organochlorine exposure and ADHD-like behaviors in childhood...
  13. ncbi request reprint On the use of biomarkers for environmental health research
    Louise Ryan
    Department of Biostatistics, Harvard School of Public Health, Boston, MA 02115, USA
    Stat Methods Med Res 13:207-25. 2004
    ....
  14. pmc Organic and inorganic mercury in neonatal rat brain after prenatal exposure to methylmercury and mercury vapor
    Hiromi Ishitobi
    Department of Environmental Medicine, School of Medicine and Dentistry, University of Rochester, Rochester, New York 14642, USA
    Environ Health Perspect 118:242-8. 2010
    ..Most of our knowledge of the neurotoxicity of Hg is based on research devoted to studying only one form at a time, mostly MeHg...
  15. ncbi request reprint Polymorphisms in the DNA repair genes XRCC1 and ERCC2, smoking, and lung cancer risk
    Wei Zhou
    Occupational Health Program, Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Cancer Epidemiol Biomarkers Prev 12:359-65. 2003
    ..In conclusion, cumulative cigarette smoking plays an important role in altering the direction and magnitude of the associations between the XRCC1 and ERCC2 polymorphisms and lung cancer risk...
  16. pmc Are environmental levels of bisphenol a associated with reproductive function in fertile men?
    Jaime Mendiola
    Department of Obstetrics and Gynecology, School of Medicine and Dentistry, University of Rochester, Rochester, New York, USA
    Environ Health Perspect 118:1286-91. 2010
    ..Rodent and in vitro studies have demonstrated the estrogenicity of bisphenol A (BPA). However, few studies have examined the relationship between human exposure to BPA and male reproductive function...
  17. ncbi request reprint Gene-environment interaction for the ERCC2 polymorphisms and cumulative cigarette smoking exposure in lung cancer
    Wei Zhou
    Occupational Health Program, Department of Environmental Health, Harvard School of Public Health, Boston, Massachusetts 02115, USA
    Cancer Res 62:1377-81. 2002
    ..A stronger gene-smoking interaction was observed for the Asp312Asn polymorphism than for the Lys751Gln polymorphism. In conclusion, cumulative cigarette smoking modifies the associations between ERCC2 polymorphisms and lung cancer risk...
  18. ncbi request reprint P53 (codon 72) and P21 (codon 31) polymorphisms alter in vivo mRNA expression of p21
    Li Su
    Occupational Health Program, Department of Environmental Health, Harvard School of Public Health, 665 Huntington Avenue, Boston, MA 02115, USA
    Lung Cancer 40:259-66. 2003
    ..Results were consistent in both patients with lung cancer (n=63) and in normal controls (n=21). In conclusion, the presence of a p53 Pro allele and/or p21 Arg allele is associated with lower downstream target gene expression of p21...
  19. pmc Early alterations in cytokine expression in adult compared to developing lung in mice after radiation exposure
    Carl J Johnston
    Departments of Pediatrics and Neonatology, University of Rochester Medical Center, Rochester, New York 14642, USA
    Radiat Res 173:522-35. 2010
    ..They may be candidates for use in marker-based biodosimetry. However, the lack of cytokine induction in early life suggests that different end points (and mitigating treatments) may be required for children...
  20. pmc Mathematical modeling of ultradeep sequencing data reveals that acute CD8+ T-lymphocyte responses exert strong selective pressure in simian immunodeficiency virus-infected macaques but still fail to clear founder epitope sequences
    Tanzy M T Love
    Department of Biostatistics and Computational Biology, University of Rochester, Rochester, New York 14642, USA
    J Virol 84:5802-14. 2010
    ..Our results suggest that a reservoir of SIV infection is preferentially formed by virus with the transmitted epitope...
  21. ncbi request reprint Comparing smoothing techniques in Cox models for exposure-response relationships
    Usha S Govindarajulu
    Yale Center for Clinical Investigation, Yale School of Medicine, New Haven, CT 06510, USA
    Stat Med 26:3735-52. 2007
    ..Overall, the penalized spline and the restricted cubic spline were closer to each other than either was to the fractional polynomial...

Research Grants1

  1. BAYESIAN BIOMARKER MODELS FOR CANCER GENETICS STUDIES
    SARAH THURSTON; Fiscal Year: 2004
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