Peter Thorne

Summary

Affiliation: University of Iowa
Country: USA

Publications

  1. pmc Murine pulmonary responses after sub-chronic exposure to aluminum oxide-based nanowhiskers
    Andrea Adamcakova-Dodd
    Department of Occupational and Environmental Health, University of Iowa, Iowa City, IA 52242, USA
    Part Fibre Toxicol 9:22. 2012
  2. pmc Safety assessment of inhaled xylitol in mice and healthy volunteers
    Lakshmi Durairaj
    Department of Medicine, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA
    Respir Res 5:13. 2004
  3. pmc Effects of copper nanoparticle exposure on host defense in a murine pulmonary infection model
    Jong Sung Kim
    Interdisciplinary Graduate Program in Human Toxicology, University of Iowa, Iowa City, 52242, USA
    Part Fibre Toxicol 8:29. 2011
  4. pmc Nanosilver induces minimal lung toxicity or inflammation in a subacute murine inhalation model
    Larissa V Stebounova
    Department of Chemistry, University of Iowa, Iowa City, IA 52242, USA
    Part Fibre Toxicol 8:5. 2011
  5. pmc An integrated model of environmental factors in adult asthma lung function and disease severity: a cross-sectional study
    Laura Trupin
    Department of Medicine, University of California San Francisco, San Francisco, CA, USA
    Environ Health 9:24. 2010
  6. ncbi request reprint Surface sampling for endotoxin assessment using electrostatic wiping cloths
    Peter S Thorne
    Occupational and Environmental Health, College of Public Health, The University of Iowa, 100 Oakdale Campus, IREH, Iowa City, IA 52242 5000, USA
    Ann Occup Hyg 49:401-6. 2005
  7. pmc Endotoxin exposure is a risk factor for asthma: the national survey of endotoxin in United States housing
    Peter S Thorne
    Department of Occupational and Environmental Health, College of Public Health, University of Iowa, 100 Oakdale Campus, 176 IREH, Iowa City, IA 52242 5000, USA
    Am J Respir Crit Care Med 172:1371-7. 2005
  8. pmc Metalworking fluid with mycobacteria and endotoxin induces hypersensitivity pneumonitis in mice
    Peter S Thorne
    The University of Iowa, College of Public Health, 100 Oakdale Campus, IREH Iowa City, IA 52242 5000, USA
    Am J Respir Crit Care Med 173:759-68. 2006
  9. ncbi request reprint Biomonitoring for assessment of organic dust-induced lung inflammation
    L J Mueller-Anneling
    Dept of Occupational and Environmental Health, The University of Iowa, College of Public Health, 100 Oakdale Campus, IREH, Iowa City, IA 52242 5000, USA
    Eur Respir J 27:1096-102. 2006
  10. pmc Environmental health impacts of concentrated animal feeding operations: anticipating hazards--searching for solutions
    Peter S Thorne
    College of Public Health, The University of Iowa, Iowa City, Iowa 52242, USA
    Environ Health Perspect 115:296-7. 2007

Research Grants

Detail Information

Publications62

  1. pmc Murine pulmonary responses after sub-chronic exposure to aluminum oxide-based nanowhiskers
    Andrea Adamcakova-Dodd
    Department of Occupational and Environmental Health, University of Iowa, Iowa City, IA 52242, USA
    Part Fibre Toxicol 9:22. 2012
    ..They are classified as high aspect ratio nanomaterials. Our aim was to assess in vivo toxicity of inhaled AO nanowhisker aerosols...
  2. pmc Safety assessment of inhaled xylitol in mice and healthy volunteers
    Lakshmi Durairaj
    Department of Medicine, Roy J and Lucille A Carver College of Medicine, University of Iowa, Iowa City, Iowa, USA
    Respir Res 5:13. 2004
    ..Xylitol is a 5-carbon sugar that can lower the airway surface salt concentration, thus enhancing innate immunity. We tested the safety and tolerability of aerosolized iso-osmotic xylitol in mice and human volunteers...
  3. pmc Effects of copper nanoparticle exposure on host defense in a murine pulmonary infection model
    Jong Sung Kim
    Interdisciplinary Graduate Program in Human Toxicology, University of Iowa, Iowa City, 52242, USA
    Part Fibre Toxicol 8:29. 2011
    ..The purpose of this study was to assess the potential pulmonary effects of inhalation and instillation exposure to copper (Cu) NPs using a model of lung inflammation and host defense...
  4. pmc Nanosilver induces minimal lung toxicity or inflammation in a subacute murine inhalation model
    Larissa V Stebounova
    Department of Chemistry, University of Iowa, Iowa City, IA 52242, USA
    Part Fibre Toxicol 8:5. 2011
    ..The objective of this study was to determine whether very small commercially available nanosilver induces pulmonary toxicity in mice following inhalation exposure...
  5. pmc An integrated model of environmental factors in adult asthma lung function and disease severity: a cross-sectional study
    Laura Trupin
    Department of Medicine, University of California San Francisco, San Francisco, CA, USA
    Environ Health 9:24. 2010
    ..We sought to evaluate the contribution of combined social and physical environmental exposures to adult asthma lung function and disease severity...
  6. ncbi request reprint Surface sampling for endotoxin assessment using electrostatic wiping cloths
    Peter S Thorne
    Occupational and Environmental Health, College of Public Health, The University of Iowa, 100 Oakdale Campus, IREH, Iowa City, IA 52242 5000, USA
    Ann Occup Hyg 49:401-6. 2005
    ..Thus, we evaluated the feasibility of wipe sampling for endotoxin environmental assessment using electrostatic wipes with or without the use of disposable examination gloves...
  7. pmc Endotoxin exposure is a risk factor for asthma: the national survey of endotoxin in United States housing
    Peter S Thorne
    Department of Occupational and Environmental Health, College of Public Health, University of Iowa, 100 Oakdale Campus, 176 IREH, Iowa City, IA 52242 5000, USA
    Am J Respir Crit Care Med 172:1371-7. 2005
    ..We assayed 2,552 house dust samples in a representative nationwide sam- ple to explore relationships between endotoxin exposures and risk factors for asthma, asthma symptoms, and medication use...
  8. pmc Metalworking fluid with mycobacteria and endotoxin induces hypersensitivity pneumonitis in mice
    Peter S Thorne
    The University of Iowa, College of Public Health, 100 Oakdale Campus, IREH Iowa City, IA 52242 5000, USA
    Am J Respir Crit Care Med 173:759-68. 2006
    ..Other constituents of in-use metalworking fluids (MWFs) may also contribute to the development of lung disease. We investigated the potential for Mycobacterium immunogenum (MI) in MWFs to induce HP...
  9. ncbi request reprint Biomonitoring for assessment of organic dust-induced lung inflammation
    L J Mueller-Anneling
    Dept of Occupational and Environmental Health, The University of Iowa, College of Public Health, 100 Oakdale Campus, IREH, Iowa City, IA 52242 5000, USA
    Eur Respir J 27:1096-102. 2006
    ..This study demonstrates the efficacy of whole blood assay as a biomarker of inhalation exposure to inflammatory agents and its use for assessing susceptibility to organic dust-induced lung inflammation...
  10. pmc Environmental health impacts of concentrated animal feeding operations: anticipating hazards--searching for solutions
    Peter S Thorne
    College of Public Health, The University of Iowa, Iowa City, Iowa 52242, USA
    Environ Health Perspect 115:296-7. 2007
    ....
  11. doi request reprint Concentrations of bioaerosols, odors, and hydrogen sulfide inside and downwind from two types of swine livestock operations
    Peter S Thorne
    Department of Occupational and Environmental Health, University of Iowa, Iowa City, Iowa 52242 5000, USA
    J Occup Environ Hyg 6:211-20. 2009
    ..Both types of swine operations produced high airborne concentrations of endotoxin, odor, hydrogen sulfide, bacteria, and fungi. Endotoxin and odors were found downwind at concentrations previously associated with adverse health effects...
  12. pmc Predictors of endotoxin levels in U.S. housing
    Peter S Thorne
    Environmental Health Sciences Research Center, College of Public Health, University of Iowa, Iowa City, Iowa 52242 5000, USA
    Environ Health Perspect 117:763-71. 2009
    ..However, few studies have evaluated predictors of household endotoxin, and none have done so for multiple locations within homes and on a national scale...
  13. pmc Evaluation of the Limulus amebocyte lysate and recombinant factor C assays for assessment of airborne endotoxin
    Peter S Thorne
    Department of Occupational and Environmental Health, University of Iowa, Iowa City, Iowa 52242, USA
    Appl Environ Microbiol 76:4988-95. 2010
    ..Both methods provided suitable lower limits of detection such that all but 19 of 1,824 samples were quantifiable...
  14. ncbi request reprint Working Group report 4: exposure assessment for biological agents
    Peter S Thorne
    College of Public Health, University of Iowa, Iowa City, IA 55242 5000, USA
    Am J Ind Med 46:419-22. 2004
    ..Endotoxin exposure assessment using the Limulus amebocyte lysate method is a high priority for harmonization because of its importance as a pulmonary inflammatory agent in many occupational settings...
  15. ncbi request reprint Evaluation of five extraction protocols for quantification of endotoxin in metalworking fluid aerosol
    Peter S Thorne
    College of Public Health, Department of Occupational and Environmental Health, 100 Oakdale Campus, IREH, The University of Iowa, Iowa City, IA 52242 5000, USA
    Ann Occup Hyg 47:31-6. 2003
    ..This study was conducted to generate multiple samples with similar mass and endotoxin loading in order to compare four alternative extraction methods with the ASTM method...
  16. ncbi request reprint Early-onset inflammatory responses in vivo to adenoviral vectors in the presence or absence of lipopolysaccharide-induced inflammation
    P S Thorne
    Department of Preventive Medicine and Environmental Health, University of Iowa, Iowa City, Iowa 52242 5000, USA
    Am J Respir Cell Mol Biol 20:1155-64. 1999
    ..These data demonstrate that replication-deficient Ad induce early inflammation and LPS-induced inflammation is not augmented by concurrent treatment with Ad...
  17. ncbi request reprint Inhalation toxicology models of endotoxin- and bioaerosol-induced inflammation
    P S Thorne
    Department of Occupational and Environmental Health, University of Iowa College of Public Health, Iowa City, IA 52242 5000, USA
    Toxicology 152:13-23. 2000
    ..In order to produce reliable data, rigorous exposure chamber design, aerosol generation systems, exposure quantitation and experimental protocols must be utilized...
  18. ncbi request reprint Indoor and outdoor air quality assessment of four wastewater treatment plants
    Joung Ae Lee
    Department of Occupational and Environmental Health, The University of Iowa, Iowa City 52242, USA
    J Occup Environ Hyg 3:36-43. 2006
    ..The results showed that the factors analyzed affected concentrations of H2S and endotoxin differently. Therefore, different control methods for endotoxin and H2S need to be considered to effectively reduce their concentrations at WWTPs...
  19. ncbi request reprint Comparison of endotoxin assays using agricultural dusts
    Stephen J Reynolds
    College of Public Health, Department of Occupational and Environmental Health, 140 IREH, University of Iowa, Iowa City, IA 52242, USA
    AIHA J (Fairfax, Va) 63:430-8. 2002
    ..The results of this study will be useful for standardization of sampling and analysis of airborne endotoxin in agriculture...
  20. ncbi request reprint Exposure to particulates, microorganisms, beta(1-3)-glucans, and endotoxins during soybean harvesting
    Chad J Roy
    The University of Iowa, College of Public Health, Department of Occupational and Environmental Health, Iowa City, IA 52242 5000, USA
    AIHA J (Fairfax, Va) 64:487-95. 2003
    ..6 x 10(4) to 4.0 x 10(8) organisms/m(3). These data indicate the potential exists for high exposures to organic dust and bioaerosols during soybean harvesting...
  21. pmc MD-2-dependent pulmonary immune responses to inhaled lipooligosaccharides: effect of acylation state
    Suzana Hadina
    Department of Occupational and Environmental Health, The University of Iowa, Iowa City, IA 52242 5000, USA
    Am J Respir Cell Mol Biol 38:647-54. 2008
    ..Hyporesponsiveness in MD-2-null mice after nasal aspiration of wild-type LOS indicate its essential role in airway responsiveness to endotoxin...
  22. pmc The potential role of concentrated animal feeding operations in infectious disease epidemics and antibiotic resistance
    Mary J Gilchrist
    University Hygienic Laboratory, Iowa City, Iowa 52242, USA
    Environ Health Perspect 115:313-6. 2007
    ....
  23. ncbi request reprint Early exposure to a nonhygienic environment alters pulmonary immunity and allergic responses
    Caroline L S George
    Department of Pediatrics, University of Iowa, Iowa City, 52242, USA
    Am J Physiol Lung Cell Mol Physiol 291:L512-22. 2006
    ..In conclusion, exposure to a nonhygienic environment did not induce significant airway neutrophilia, yet altered the population of immunologically active cells in the lung and reduced subsequent allergic inflammation...
  24. pmc Asthma and farm exposures in a cohort of rural Iowa children
    James A Merchant
    Department of Occupational and Environmental Health, University of Iowa College of Public Health, Iowa City, Iowa, USA
    Environ Health Perspect 113:350-6. 2005
    ....
  25. ncbi request reprint A small whole-body exposure chamber for laboratory use
    PATRICK T O'SHAUGHNESSY
    Department of Occupational and Environmental Health, College of Public Health, University of Iowa, 100 Oakdale Campus, 137 IREH, Iowa City, IA 52242 5000, USA
    Inhal Toxicol 15:251-63. 2003
    ..8% and 11.0%, respectively. These CV values are comparable to those obtained from similar studies involving other inhalation exposure chambers...
  26. ncbi request reprint Altered surfactant protein A gene expression and protein metabolism associated with repeat exposure to inhaled endotoxin
    Caroline L S George
    Department of Pediatrics, Division of Pediatric Critical Care, University of Iowa, Iowa City, IA 52242, USA
    Am J Physiol Lung Cell Mol Physiol 285:L1337-44. 2003
    ..Furthermore, these alterations in SP-A gene activity and protein metabolism are dependent on an intact endotoxin signaling system...
  27. pmc Exposures to the Kuwait oil fires and their association with asthma and bronchitis among gulf war veterans
    Jeffrey L Lange
    Department of Occupational and Environmental Health, College of Public Health, College of Medicine, University of Iowa, Iowa City, Iowa, USA
    Environ Health Perspect 110:1141-6. 2002
    ..In contrast, there was no association between the modeled exposure and any of the outcomes. These findings do not support speculation that exposures to oil-fire smoke caused respiratory symptoms among veterans...
  28. ncbi request reprint Monitoring risks in association with exposure levels among wastewater treatment plant workers
    Joung Ae Lee
    Health Protection Office, The University of Iowa, Iowa City, IA 52246, USA
    J Occup Environ Med 49:1235-48. 2007
    ..To investigate the relationship between exposure to hydrogen sulfide and endotoxin during specific job tasks and health symptoms among wastewater treatment plant (WWTP) workers...
  29. pmc Inhalation exposure study of titanium dioxide nanoparticles with a primary particle size of 2 to 5 nm
    Vicki H Grassian
    Department of Chemistry, University of Iowa, Iowa City, Iowa 52242, USA
    Environ Health Perspect 115:397-402. 2007
    ..Nanotechnology offers great promise in many industrial applications. However, little is known about the health effects of manufactured nanoparticles, the building blocks of nanomaterials...
  30. ncbi request reprint Asthma prevalence and morbidity among rural Iowa schoolchildren
    Elizabeth Chrischilles
    Department of Epidemiology, College of Public Health, The University of Iowa, Iowa City, Iowa 52242, USA
    J Allergy Clin Immunol 113:66-71. 2004
    ..There are conflicting findings about the prevalence of asthma among farm and nonfarm children...
  31. pmc Community health and socioeconomic issues surrounding concentrated animal feeding operations
    Kelley J Donham
    College of Public Health, The University of Iowa, Iowa City, Iowa 52242, USA
    Environ Health Perspect 115:317-20. 2007
    ....
  32. pmc Novispirin G10-induced lung toxicity in a Klebsiella pneumoniae infection model
    Karen H Bartlett
    Department of Occupational and Environmental Health, The University of Iowa, Iowa City, Iowa 52242, USA
    Antimicrob Agents Chemother 47:3901-6. 2003
    ..This finding establishes the importance of investigating candidate antimicrobial agents in an in vivo infection model...
  33. pmc Ambient endotoxin concentrations in PM10 from Southern California
    Linda Mueller-Anneling
    College of Public Health, The University of Iowa, 100 Oakdale Campus, IREH, Iowa City, IA 52242 5000, USA
    Environ Health Perspect 112:583-8. 2004
    ....
  34. ncbi request reprint Women in the Gulf War: combat experience, exposures, and subsequent health care use
    Caroline P Carney
    Department of Psychiatry, University of Iowa College of Medicine, Iowa City, Iowa 52242, USA
    Mil Med 168:654-61. 2003
    ..If these important differences in exposures and health care use are confirmed in other studies, optimal training and deployment preparedness strategies should be reconsidered...
  35. ncbi request reprint Reduction in the bactericidal activity of selected cathelicidin peptides by bovine calf serum or exogenous endotoxin
    Karen H Bartlett
    Department of Occupational and Environmental Health, College of Public Health, The University of Iowa, 100 Oakdale Campus, IREH, Iowa City, IA 52242, USA
    Int J Antimicrob Agents 23:606-12. 2004
    ..LPS-binding efficiency was not correlated with antimicrobial activity in complex media. Additionally, LPS- and serum-binding may interfere with the antimicrobial activity of peptides in complex media...
  36. pmc Modulation of reactive oxygen species by Rac1 or catalase prevents asbestos-induced pulmonary fibrosis
    Shubha Murthy
    Department of Internal Medicine, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA
    Am J Physiol Lung Cell Mol Physiol 297:L846-55. 2009
    ..For the first time, these results demonstrate that Rac1 plays a crucial role in asbestos-induced pulmonary fibrosis. Moreover, it suggests that a simple intervention may be useful to prevent progression of the disease...
  37. pmc Innovative application of fluoro tagging to trace airborne particulate and gas-phase polybrominated diphenyl ether exposures
    Johannes Klösener
    Department of Occupational and Environmental Health, High Resolution Mass Spectrometry Facility, and Interdisciplinary Graduate Program in Human Toxicology, University of Iowa, 100 Oakdale Campus, Iowa City, Iowa 52242, USA
    Chem Res Toxicol 22:179-86. 2009
    ..Our study is of fundamental importance to the development of xenobiotic tracers for monitoring routes of human exposure to PBDEs and understanding uptake of PBDEs from particles and vapors...
  38. pmc Time course of congener uptake and elimination in rats after short-term inhalation exposure to an airborne polychlorinated biphenyl (PCB) mixture
    Xin Hu
    Interdisciplinary Graduate Program in Human Toxicology, Department of Occupational and Environmental Health, University of Iowa, Iowa City, Iowa 52242, USA
    Environ Sci Technol 44:6893-900. 2010
    ..Selective uptake and elimination led to accumulation of a distinct congener spectrum in tissue. Minimal evidence of toxicity was observed...
  39. ncbi request reprint Antibiotics delay but do not prevent bacteremia and lung injury in murine sepsis
    Kevin C Doerschug
    Department of Internal Medicine, University of Iowa College of Medicine, Iowa City, IA, USA
    Crit Care Med 32:489-94. 2004
    ..To circumvent the effect of antibiotics on cultures, we used polymerase chain reaction to detect bacteria...
  40. pmc Evaluation of a low-cost electrostatic dust fall collector for indoor air endotoxin exposure assessment
    Ilka Noss
    Institute for Risk Assessment Sciences, Utrecht University, Utrecht, The Netherlands
    Appl Environ Microbiol 74:5621-7. 2008
    ..We therefore conclude that measuring endotoxin levels with the EDC is a valid measure of average airborne endotoxin exposure, while reproducibility over time is at least equivalent to that of reservoir dust analyses...
  41. ncbi request reprint Health-based occupational exposure limits for high molecular weight sensitizers: how long is the road we must travel?
    Dick Heederik
    Institute for Risk Assessment Sciences, Division of Environmental and Occupational Health, Utrecht University, PO Box 80176, The Netherlands
    Ann Occup Hyg 46:439-46. 2002
    ..The major practical constraint at this moment seems to be the absence of well-standardized measurement techniques (immunoassays) for the evaluation of allergen exposure in the field...
  42. pmc Exposure to multiple indoor allergens in US homes and its relationship to asthma
    Päivi M Salo
    National Institute of Environmental Health Sciences, National Institutes of Health, Research Triangle Park, NC 27709, USA
    J Allergy Clin Immunol 121:678-684.e2. 2008
    ..The National Survey of Lead and Allergens in Housing was the first population-based study to measure indoor allergen levels in US homes...
  43. pmc First National Survey of Lead and Allergens in Housing: survey design and methods for the allergen and endotoxin components
    Patrick J Vojta
    Division of Intramural Research, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina 27709, USA
    Environ Health Perspect 110:527-32. 2002
    ..S. households, their distribution by various housing characteristics, and their associations with allergic diseases such as asthma and rhinitis...
  44. pmc Optimization of airborne endotoxin exposure assessment: effects of filter type, transport conditions, extraction solutions, and storage of samples and extracts
    Suzanne Spaan
    Institute for Risk Assessment Sciences, Division Environmental Epidemiology, Utrecht University, P O Box 80178, 3508 TD Utrecht, The Netherlands
    Appl Environ Microbiol 73:6134-43. 2007
    ..05% Tween 20 in the assay solution had an additive effect. Thus, this study investigated gaps in the CEN protocol and provides data with which to fully specify a protocol for standardization of endotoxin exposure assessment...
  45. ncbi request reprint Impact of the home indoor environment on adult asthma and rhinitis
    Paul D Blanc
    Department of Medicine, Cardiovascular Research Institute, University of California San Francisco, San Francisco, CA 94117, USA
    J Occup Environ Med 47:362-72. 2005
    ..We sought to study the combined effects of multiple home indoor environmental exposures in adult asthma and rhinitis...
  46. ncbi request reprint History and results of the two inter-laboratory round robin endotoxin assay studies on cotton dust
    David T W Chun
    Cotton Quality Research Station, Agricultural Research Service, U S Department of Agriculture, Clemson, South Carolina 29633, USA
    Am J Ind Med 49:301-6. 2006
    ..When different laboratories assay identical samples, the levels differ. The objective of this research was to evaluate the intra- and inter-laboratory variability for 13 laboratories measuring endotoxin in cotton dust...
  47. ncbi request reprint Inter- and intraindividual variation of endotoxin- and beta(1 --> 3)-glucan-induced cytokine responses in a whole blood assay
    Inge M Wouters
    Institute for Risk Assessment Sciences, Division of Environmental and Occupational Health, Utrecht University, The Netherlands
    Toxicol Ind Health 18:15-27. 2002
    ....
  48. ncbi request reprint Interlaboratory evaluation of endotoxin analyses in agricultural dusts--comparison of LAL assay and mass spectrometry
    Stephen J Reynolds
    Department of Environmental and Radiological Health Sciences, Colorado State University, Ft Collins, CO 80523 1681, USA
    J Environ Monit 7:1371-7. 2005
    ..GC-MS may be of use when comparing across heterogeneous environments and should be considered for inclusion in future studies of human health outcomes...
  49. ncbi request reprint Airborne endotoxin predicts symptoms in non-mouse-sensitized technicians and research scientists exposed to laboratory mice
    Karin A Pacheco
    Department of Medicine, Division of Environmental and Occupational Health Sciences, National Jewish Medical and Research Center, 1400 Jackson Street, Denver, CO 80206, USA
    Am J Respir Crit Care Med 167:983-90. 2003
    ..8, p = 0.003). We conclude that airborne endotoxin is associated with respiratory symptoms to mice in non-mouse-sensitized scientists and technicians...
  50. pmc Endotoxin in inner-city homes: associations with wheeze and eczema in early childhood
    Matthew S Perzanowski
    Columbia s Center for Children s Environmental Health, Columbia University, New York, NY 10032, USA
    J Allergy Clin Immunol 117:1082-9. 2006
    ..The relevance of this aspect of the hygiene hypothesis to US inner-city communities that have disproportionately high asthma prevalence has not been determined...
  51. ncbi request reprint Characterization of endotoxin and mouse allergen exposures in mouse facilities and research laboratories
    Karin A Pacheco
    Department of Medicine, National Jewish Medical and Research Center, Denver, CO, USA
    Ann Occup Hyg 50:563-72. 2006
    ..Endotoxin and mouse allergen are derived from the same animal source, but have different physicochemical attributes. It is not known if airborne exposures to these agents are correlated in the laboratory animal workplace...
  52. pmc Dog ownership enhances symptomatic responses to air pollution in children with asthma
    Rob McConnell
    Department of Preventive Medicine, University of Southern California, Los Angeles, California, USA
    Environ Health Perspect 114:1910-5. 2006
    ..Experimental data suggest that asthma exacerbation by ambient air pollutants is enhanced by exposure to endotoxin and allergens; however, there is little supporting epidemiologic evidence...
  53. ncbi request reprint Personal exposures to inorganic and organic dust in manual harvest of California citrus and table grapes
    Kiyoung Lee
    Department of Epidemiology and Preventive Medicine, Western Center for Agricultural Health and Safety, University of California, Davis, Calif, USA
    J Occup Environ Hyg 1:505-14. 2004
    ..The degree of vigorous contact with foliage appeared to be a significant determining factor of exposures in manual harvesting...
  54. pmc Impacts of waste from concentrated animal feeding operations on water quality
    JoAnn Burkholder
    North Carolina State University, Raleigh, North Carolina, USA
    Environ Health Perspect 115:308-12. 2007
    ..Last, there is a need to promote and enforce best practices to minimize inputs of nutrients and toxicants from CAFOs into freshwater and marine ecosystems...
  55. pmc Monitoring and modeling of emissions from concentrated animal feeding operations: overview of methods
    Bryan Bunton
    Iowa Department of Natural Resources, Des Moines, Iowa, USA
    Environ Health Perspect 115:303-7. 2007
    ..Additional data are needed to obtain reliable emission rates from CAFOs...
  56. pmc Health effects of airborne exposures from concentrated animal feeding operations
    Dick Heederik
    University of Utrecht, Utrecht, The Netherlands
    Environ Health Perspect 115:298-302. 2007
    ....
  57. pmc Characterization of airborne molds, endotoxins, and glucans in homes in New Orleans after Hurricanes Katrina and Rita
    Carol Y Rao
    Epidemic Intelligence Service, Mycotic Diseases Branch, Centers for Disease Control and Prevention, 1600 Clifton Rd NE, MS C09, Atlanta, GA 30333, USA
    Appl Environ Microbiol 73:1630-4. 2007
    ..The species and concentrations were different from those previously reported for non-water-damaged buildings in the southeastern United States...
  58. ncbi request reprint Second inter-laboratory study comparing endotoxin assay results from cotton dust
    David T W Chun
    Cotton Quality Research Station, Agricultural Research Service, US Department of Agriculture, P O Box 792, Clemson, SC 29633, USA
    Ann Agric Environ Med 9:49-53. 2002
    ..The results of this second round robin endotoxin assay study indicate that differences between laboratories are still high, but most of the laboratories could discern the cotton dusts with the different levels of endotoxin...
  59. pmc Effect of extraction and assay media on analysis of airborne endotoxin
    Suzanne Spaan
    Institute for Risk Assessment Sciences, Environmental Epidemiology Division, Utrecht University, P O Box 80178, 3508 TD Utrecht, The Netherlands
    Appl Environ Microbiol 74:3804-11. 2008
    ..In conclusion, of the media tested, only Tween enhances the efficiency of endotoxin extraction from airborne dust samples in a consistent manner. We recommend extraction in PFW-Tween combined with dilution and LAL analysis in PFW...
  60. ncbi request reprint Six month tracking of microbial growth in a metalworking fluid after system cleaning and recharging
    Marc Veillette
    Centre de Recherche, Hopital Laval, Institut Universitaire de Cardiologie et de Pneumologie and Département de Biochimie et de Microbiologie de l Université Laval, 2725 Chemin Ste Foy, Quebec, Ste Foy, G1V 4G5, Canada
    Ann Occup Hyg 48:541-6. 2004
    ..This study demonstrates that standard methods for cleaning MWF systems are inadequate since residual bacteria in the system can rapidly repopulate the newly charged MWF...
  61. ncbi request reprint Toenail arsenic content and cutaneous melanoma in Iowa
    Laura E Beane Freeman
    Division of Cancer Prevention, National Cancer Institute, Bethesda, MD, USA
    Am J Epidemiol 160:679-87. 2004
    ..03). The arsenic-melanoma findings in this study are not known to have been previously reported in observational epidemiologic studies involving incident cutaneous melanoma. Therefore, the findings warrant confirmation...
  62. pmc Mold and endotoxin levels in the aftermath of Hurricane Katrina: a pilot project of homes in New Orleans undergoing renovation
    Ginger L Chew
    Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, New York 10034 4206, USA
    Environ Health Perspect 114:1883-9. 2006
    ..After Hurricane Katrina, many New Orleans homes remained flooded for weeks, promoting heavy microbial growth...

Research Grants9

  1. Exposure Intervention in a Rural Pediatric Asthma Cohort
    Peter Thorne; Fiscal Year: 2005
    ..Detailed health and home hygiene questionnaires and home inspections will be conducted at baseline and one year later, as will child spirometry. ..
  2. ENVIRONMENTAL HEALTH SCIENCES RESEARCH CENTER
    Peter Thorne; Fiscal Year: 2007
    ..During that time it has had two Directors, Dr. James Merchant (1993-2003) and Dr. Peter Thorne (2003-present)...