WALLACE BRUCE THORESON

Summary

Affiliation: University of Nebraska Medical Center
Country: USA

Publications

  1. Warren T, Van Hook M, Tranchina D, Thoreson W. Kinetics of Inhibitory Feedback from Horizontal Cells to Photoreceptors: Implications for an Ephaptic Mechanism. J Neurosci. 2016;36:10075-88 pubmed publisher
    ..By eliminating the proposed ephaptic mechanism for HC feedback regulation of photoreceptor Ca(2+) channels, our data support earlier proposals that synaptic cleft pH changes are more likely responsible. ..
  2. Thoreson W, Miller R. Removal of extracellular chloride suppresses transmitter release from photoreceptor terminals in the mudpuppy retina. J Gen Physiol. 1996;107:631-42 pubmed
    ..Thus, it is possible that control of [Cl-] in and around photoreceptors may regulate glutamate release from these cells...
  3. request reprint
    Thoreson W, Nitzan R, Miller R. Chloride efflux inhibits single calcium channel open probability in vertebrate photoreceptors: chloride imaging and cell-attached patch-clamp recordings. Vis Neurosci. 2000;17:197-206 pubmed
    ..Examination of the open and closed time distributions suggests that the reduction in open probability arises from increases in closed-state dwell times. Changes in intracellular [Cl-] may thus modulate photoreceptor Ca2+ channels...
  4. request reprint
    Thoreson W, Bryson E, Rabl K. Reciprocal interactions between calcium and chloride in rod photoreceptors. J Neurophysiol. 2003;90:1747-53 pubmed
    ..These findings support the hypothesis that feedback interactions between Ca2+- and Ca2+-activated Cl- channels may contribute to the regulation of presynaptic Ca2+ currents involved in synaptic transmission from rod photoreceptors...

Locale

Detail Information

Publications4

  1. Warren T, Van Hook M, Tranchina D, Thoreson W. Kinetics of Inhibitory Feedback from Horizontal Cells to Photoreceptors: Implications for an Ephaptic Mechanism. J Neurosci. 2016;36:10075-88 pubmed publisher
    ..By eliminating the proposed ephaptic mechanism for HC feedback regulation of photoreceptor Ca(2+) channels, our data support earlier proposals that synaptic cleft pH changes are more likely responsible. ..
  2. Thoreson W, Miller R. Removal of extracellular chloride suppresses transmitter release from photoreceptor terminals in the mudpuppy retina. J Gen Physiol. 1996;107:631-42 pubmed
    ..Thus, it is possible that control of [Cl-] in and around photoreceptors may regulate glutamate release from these cells...
  3. request reprint
    Thoreson W, Nitzan R, Miller R. Chloride efflux inhibits single calcium channel open probability in vertebrate photoreceptors: chloride imaging and cell-attached patch-clamp recordings. Vis Neurosci. 2000;17:197-206 pubmed
    ..Examination of the open and closed time distributions suggests that the reduction in open probability arises from increases in closed-state dwell times. Changes in intracellular [Cl-] may thus modulate photoreceptor Ca2+ channels...
  4. request reprint
    Thoreson W, Bryson E, Rabl K. Reciprocal interactions between calcium and chloride in rod photoreceptors. J Neurophysiol. 2003;90:1747-53 pubmed
    ..These findings support the hypothesis that feedback interactions between Ca2+- and Ca2+-activated Cl- channels may contribute to the regulation of presynaptic Ca2+ currents involved in synaptic transmission from rod photoreceptors...