Padmaja B Thomas

Summary

Affiliation: University of Southern California
Country: USA

Publications

  1. pmc Identification of Notch-1 expression in the limbal basal epithelium
    Padmaja B Thomas
    Ocular Surface Center, Doheny Eye Institute, Los Angeles, CA 90033, USA
    Mol Vis 13:337-44. 2007
  2. pmc Adeno-associated virus-mediated IL-10 gene transfer suppresses lacrimal gland immunopathology in a rabbit model of autoimmune dacryoadenitis
    Padmaja B Thomas
    Ocular Surface Center, Doheny Eye Institute, Los Angeles, California 90033, USA
    Invest Ophthalmol Vis Sci 51:5137-44. 2010
  3. doi request reprint Autoimmune dacryoadenitis and sialadenitis induced in rabbits by intravenous injection of autologous lymphocytes activated ex vivo against lacrimal antigens
    Rui Hua Wei
    Ocular Surface Center, Doheny Eye Institute, Los Angeles, CA 90033, USA
    Cornea 31:693-701. 2012
  4. pmc Distinct dacryoadenitides autoadoptively transferred to rabbits by different subpopulations of lymphocytes activated ex vivo
    Padmaja B Thomas
    Ocular Surface Center, Doheny Eye Institute, Los Angeles, CA 90033, USA
    Cornea 29:1153-62. 2010
  5. ncbi request reprint Transepithelial bioelectrical properties of rabbit acinar cell monolayers on polyester membrane scaffolds
    Shivaram Selvam
    Mork Family Department of Chemical Engineering and Materials Science, Viterbi School of Engineering, University of Southern California, Los Angeles, CA, USA
    Am J Physiol Cell Physiol 293:C1412-9. 2007
  6. pmc Long-term topical cyclosporine treatment improves tear production and reduces keratoconjunctivitis in rabbits with induced autoimmune dacryoadenitis
    Padmaja B Thomas
    Ocular Surface Center, Department of Ophthalmology, Doheny Eye Institute, Los Angeles, CA 90033, USA
    J Ocul Pharmacol Ther 25:285-92. 2009
  7. pmc Current status of gene delivery and gene therapy in lacrimal gland using viral vectors
    Shivaram Selvam
    Mork Family Department of Chemical Engineering and Materials Science, Viterbi School of Engineering, University of Southern California, Los Angeles, CA 90089, USA
    Adv Drug Deliv Rev 58:1243-57. 2006
  8. ncbi request reprint Ocular surface reconstruction: recent advances and future outlook
    Samuel C Yiu
    Ocular Surface Center, Doheny Eye Institute, Los Angeles, CA 90033, USA
    Curr Opin Ophthalmol 18:509-14. 2007
  9. ncbi request reprint Tissue engineering: current and future approaches to ocular surface reconstruction
    Shivaram Selvam
    Department of Chemical Engineering, Viterbi School of Engineering, University of Southern California, Los Angeles, CA 90033, USA
    Ocul Surf 4:120-36. 2006
  10. doi request reprint A novel approach for subretinal implantation of ultrathin substrates containing stem cell-derived retinal pigment epithelium monolayer
    Yuntao Hu
    Doheny Eye Institute, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA
    Ophthalmic Res 48:186-91. 2012

Collaborators

Detail Information

Publications11

  1. pmc Identification of Notch-1 expression in the limbal basal epithelium
    Padmaja B Thomas
    Ocular Surface Center, Doheny Eye Institute, Los Angeles, CA 90033, USA
    Mol Vis 13:337-44. 2007
    ..To determine whether Notch-1, a ligand-activated transmembrane receptor known to maintain cells in an undifferentiated state, primarily progenitor cells in other systems, could be used as a stem cell marker in human limbal epithelium...
  2. pmc Adeno-associated virus-mediated IL-10 gene transfer suppresses lacrimal gland immunopathology in a rabbit model of autoimmune dacryoadenitis
    Padmaja B Thomas
    Ocular Surface Center, Doheny Eye Institute, Los Angeles, California 90033, USA
    Invest Ophthalmol Vis Sci 51:5137-44. 2010
    ..To evaluate the effect of adeno-associated virus (AAV) vector-mediated viral (v)IL-10 gene expression on lacrimal gland (LG) immunopathology and ocular surface disease in a rabbit model of induced autoimmune dacryoadenitis (ID)...
  3. doi request reprint Autoimmune dacryoadenitis and sialadenitis induced in rabbits by intravenous injection of autologous lymphocytes activated ex vivo against lacrimal antigens
    Rui Hua Wei
    Ocular Surface Center, Doheny Eye Institute, Los Angeles, CA 90033, USA
    Cornea 31:693-701. 2012
    ..The purpose of the present study was to determine the ability of intravenously (IV) injected autologous stimulated lymphocytes to home to the LG and salivary gland (SG) and induce disease...
  4. pmc Distinct dacryoadenitides autoadoptively transferred to rabbits by different subpopulations of lymphocytes activated ex vivo
    Padmaja B Thomas
    Ocular Surface Center, Doheny Eye Institute, Los Angeles, CA 90033, USA
    Cornea 29:1153-62. 2010
    ..To test whether CD4+ T cells proliferate in mixed cell reactions with autologous lacrimal gland (LG) acinar cells and whether these cells can autoadoptively transfer disease...
  5. ncbi request reprint Transepithelial bioelectrical properties of rabbit acinar cell monolayers on polyester membrane scaffolds
    Shivaram Selvam
    Mork Family Department of Chemical Engineering and Materials Science, Viterbi School of Engineering, University of Southern California, Los Angeles, CA, USA
    Am J Physiol Cell Physiol 293:C1412-9. 2007
    ..In summary, rabbit lacrimal acinar cell monolayers generate a Cl(-)-dependent, ouabain-sensitive AP --> BL I(sc) in response to CCh, consistent with current models for Na(+)-dependent Cl(-) secretion...
  6. pmc Long-term topical cyclosporine treatment improves tear production and reduces keratoconjunctivitis in rabbits with induced autoimmune dacryoadenitis
    Padmaja B Thomas
    Ocular Surface Center, Department of Ophthalmology, Doheny Eye Institute, Los Angeles, CA 90033, USA
    J Ocul Pharmacol Ther 25:285-92. 2009
    ..To use a rabbit model of induced autoimmune dacryoadenitis to evaluate the efficacy of topical ophthalmic cyclosporine A (CsA)...
  7. pmc Current status of gene delivery and gene therapy in lacrimal gland using viral vectors
    Shivaram Selvam
    Mork Family Department of Chemical Engineering and Materials Science, Viterbi School of Engineering, University of Southern California, Los Angeles, CA 90089, USA
    Adv Drug Deliv Rev 58:1243-57. 2006
    ..This review will discuss the developments related to gene delivery and gene therapy in the lacrimal gland using several viral vector systems...
  8. ncbi request reprint Ocular surface reconstruction: recent advances and future outlook
    Samuel C Yiu
    Ocular Surface Center, Doheny Eye Institute, Los Angeles, CA 90033, USA
    Curr Opin Ophthalmol 18:509-14. 2007
    ..Left untreated, these conditions can progress to vision loss or destruction of the globe itself. This review discusses the most recent and relevant clinical and experimental advances in the treatment options for ocular surface disorders...
  9. ncbi request reprint Tissue engineering: current and future approaches to ocular surface reconstruction
    Shivaram Selvam
    Department of Chemical Engineering, Viterbi School of Engineering, University of Southern California, Los Angeles, CA 90033, USA
    Ocul Surf 4:120-36. 2006
    ....
  10. doi request reprint A novel approach for subretinal implantation of ultrathin substrates containing stem cell-derived retinal pigment epithelium monolayer
    Yuntao Hu
    Doheny Eye Institute, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA
    Ophthalmic Res 48:186-91. 2012
    ....
  11. ncbi request reprint Tissue-engineered tear secretory system: functional lacrimal gland acinar cells cultured on matrix protein-coated substrata
    Shivaram Selvam
    Department of Chemical Engineering, Viterbi School of Engineering, University of Southern California, Los Angeles, California 90089, USA
    J Biomed Mater Res B Appl Biomater 80:192-200. 2007
    ..Our study demonstrates that PLLA supported the morphological and physiological properties of purified rabbit lacrimal gland epithelial cells more successfully than the others...