Biju B Thomas

Summary

Affiliation: University of Southern California
Country: USA

Publications

  1. ncbi Modulatory influence of stimulus parameters on optokinetic head-tracking response
    Biju B Thomas
    Doheny Retina Institute, Doheny Eye Institute, 1450 San Pablo St, Los Angeles, CA 90033, United States
    Neurosci Lett 479:92-6. 2010
  2. ncbi Behavioral evaluation of visual function of rats using a visual discrimination apparatus
    Biju B Thomas
    Department of Ophthalmology, Doheny Eye Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
    J Neurosci Methods 162:84-90. 2007
  3. ncbi BDNF-treated retinal progenitor sheets transplanted to degenerate rats: improved restoration of visual function
    Magdalene J Seiler
    Ophthalmology USC, Doheny, Los Angeles, CA, USA
    Exp Eye Res 86:92-104. 2008
  4. ncbi Visual functional effects of constant blue light in a retinal degenerate rat model
    Biju B Thomas
    Doheny Retina Institute, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA
    Photochem Photobiol 83:759-65. 2007
  5. ncbi Retinal transplantation. A treatment strategy for retinal degenerative diseases
    Biju B Thomas
    Dept. Ophthalmology, Doheny Retina Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
    Adv Exp Med Biol 572:367-76. 2006
  6. ncbi Retinal transplants restore visual responses: trans-synaptic tracing from visually responsive sites labels transplant neurons
    Magdalene J Seiler
    Ophthalmology USC, Doheny Eye Institute, 1355 San Pablo Street, DVRC 402, Los Angeles, CA 90033, USA
    Eur J Neurosci 28:208-20. 2008
  7. ncbi Optokinetic test to evaluate visual acuity of each eye independently
    Biju B Thomas
    Department of Ophthalmology, Doheny Retina Institute/DVRC 402, Keck School of Medicine at the University of Southern California, 1355 San Pablo St, Los Angeles, CA 90033, USA
    J Neurosci Methods 138:7-13. 2004
  8. ncbi Light response differences in the superior colliculus of albino and pigmented rats
    Biju B Thomas
    Department of Ophthalmology, Doheny Retina Institute, Doheny Eye Institute, Keck School of Medicine, University of Southern California, DVRC 402, 1355 San Pablo St, Los Angeles, CA 90033, USA
    Neurosci Lett 385:143-7. 2005
  9. ncbi Retinal transplants evaluated by optical coherence tomography in photoreceptor degenerate rats
    Biju B Thomas
    Department of Ophthalmology, Doheny Retina Institute, Keck School of Medicine, University of Southern California, 1450 San Pablo Street, Los Angeles, CA 90033, USA
    J Neurosci Methods 151:186-93. 2006
  10. ncbi Revisiting nestin expression in retinal progenitor cells in vitro and after transplantation in vivo
    Guanting Qiu
    Department of Ophthalmology, Doheny Retina Institute, Keck School of Medicine, at the University of Southern California, 1450 Pablo St DEI 3610, Los Angeles, CA, 90033 3699, USA
    Exp Eye Res 84:1047-59. 2007

Collaborators

Detail Information

Publications14

  1. ncbi Modulatory influence of stimulus parameters on optokinetic head-tracking response
    Biju B Thomas
    Doheny Retina Institute, Doheny Eye Institute, 1450 San Pablo St, Los Angeles, CA 90033, United States
    Neurosci Lett 479:92-6. 2010
    ..This study highlights the importance of careful selection of appropriate stimulus parameters for testing optokinetic head-tracking response in RD animals...
  2. ncbi Behavioral evaluation of visual function of rats using a visual discrimination apparatus
    Biju B Thomas
    Department of Ophthalmology, Doheny Eye Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
    J Neurosci Methods 162:84-90. 2007
    ..03, paired t-test). This apparatus could be useful to train rats at a very early age to distinguish between two different visual stimuli and may be effective for visual functional evaluations following therapeutic interventions...
  3. ncbi BDNF-treated retinal progenitor sheets transplanted to degenerate rats: improved restoration of visual function
    Magdalene J Seiler
    Ophthalmology USC, Doheny, Los Angeles, CA, USA
    Exp Eye Res 86:92-104. 2008
    ..The mechanism of the BDNF effects--either promoting functional integration between the transplant and the host retina and/or synergistic action with other putative humoral factors released by the RPCs--still needs to be elucidated...
  4. ncbi Visual functional effects of constant blue light in a retinal degenerate rat model
    Biju B Thomas
    Doheny Retina Institute, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA
    Photochem Photobiol 83:759-65. 2007
    ..Histological evaluation showed reduction of the rod population in the central area of the light-damaged retina. Exposure to constant BL considerably reduces the residual visual responses in a rapid degenerating RD rat model...
  5. ncbi Retinal transplantation. A treatment strategy for retinal degenerative diseases
    Biju B Thomas
    Dept. Ophthalmology, Doheny Retina Institute, Keck School of Medicine, University of Southern California, Los Angeles, CA, USA
    Adv Exp Med Biol 572:367-76. 2006
    ..Modified functional evaluation techniques permit better understanding of the physiological mechanisms underlying visual improvement in animal models...
  6. ncbi Retinal transplants restore visual responses: trans-synaptic tracing from visually responsive sites labels transplant neurons
    Magdalene J Seiler
    Ophthalmology USC, Doheny Eye Institute, 1355 San Pablo Street, DVRC 402, Los Angeles, CA 90033, USA
    Eur J Neurosci 28:208-20. 2008
    ..This study provides anatomical evidence that synaptic connections between fetal retinal transplants and host retinas contribute to the visual responses in the SC...
  7. ncbi Optokinetic test to evaluate visual acuity of each eye independently
    Biju B Thomas
    Department of Ophthalmology, Doheny Retina Institute/DVRC 402, Keck School of Medicine at the University of Southern California, 1355 San Pablo St, Los Angeles, CA 90033, USA
    J Neurosci Methods 138:7-13. 2004
    ..In conclusion, contributions from the fellow eye to the optokinetic tracking response can be limited by this testing modification, which is useful for evaluation of treatment effects to one eye...
  8. ncbi Light response differences in the superior colliculus of albino and pigmented rats
    Biju B Thomas
    Department of Ophthalmology, Doheny Retina Institute, Doheny Eye Institute, Keck School of Medicine, University of Southern California, DVRC 402, 1355 San Pablo St, Los Angeles, CA 90033, USA
    Neurosci Lett 385:143-7. 2005
    ..This can be attributed to the transmission of rod-driven responses. The differences observed in the light response characteristics of albino rats may be indicative of their visual abnormalities...
  9. ncbi Retinal transplants evaluated by optical coherence tomography in photoreceptor degenerate rats
    Biju B Thomas
    Department of Ophthalmology, Doheny Retina Institute, Keck School of Medicine, University of Southern California, 1450 San Pablo Street, Los Angeles, CA 90033, USA
    J Neurosci Methods 151:186-93. 2006
    ..OCT is a useful technique for in vivo screening and evaluation of retinal transplants. This technique determines surgical outcomes at a much earlier stage...
  10. ncbi Revisiting nestin expression in retinal progenitor cells in vitro and after transplantation in vivo
    Guanting Qiu
    Department of Ophthalmology, Doheny Retina Institute, Keck School of Medicine, at the University of Southern California, 1450 Pablo St DEI 3610, Los Angeles, CA, 90033 3699, USA
    Exp Eye Res 84:1047-59. 2007
    ..The role of nestin as a unique neural stem/progenitor cell marker should be reconsidered. Nestin expression during RPC maturation appears to be different in vitro versus in vivo...
  11. ncbi Superior colliculus responses to light - preserved by transplantation in a slow degeneration rat model
    Biju B Thomas
    Department of Ophthalmology, Doheny Eye Institute, University of Southern California, 1450 San Pablo St, Los Angeles, CA 90033, USA
    Exp Eye Res 79:29-39. 2004
    ..30-50 msec). CONCLUSIONS: Fetal retinal sheet transplantation showed a long-term rescue effect on visual function in this animal model of slow photoreceptor degeneration...
  12. ncbi A novel approach for subretinal implantation of ultrathin substrates containing stem cell-derived retinal pigment epithelium monolayer
    Yuntao Hu
    Doheny Eye Institute, Keck School of Medicine of the University of Southern California, Los Angeles, CA, USA
    Ophthalmic Res 48:186-91. 2012
    ....
  13. ncbi Structure and function of embryonic rat retinal sheet transplants
    Qing Peng
    Department of Ophthalmology, First Hospital of Shanxi Medical University, Taiyuan, Shanxi, People s Republic of China
    Curr Eye Res 32:781-9. 2007
    ..To evaluate retinal sheet transplants in S334ter-line-3 retinal degenerate rats by comparing visual responses recorded electrophysiologically with morphology based on light and electron microscopy...
  14. ncbi Transsynaptic virus tracing from host brain to subretinal transplants
    Magdalene J Seiler
    Department of Ophthalmology and Visual Sciences, University of Louisville, Louisville, KY, USA
    Eur J Neurosci 21:161-72. 2005
    ..This study provides evidence that PRV spreads in the retina as in other parts of the CNS and is useful to outline transplant-host circuitry...