Robert Thoma

Summary

Affiliation: University of New Mexico
Country: USA

Publications

  1. pmc Perturbation of the glutamate-glutamine system in alcohol dependence and remission
    Robert Thoma
    MIND Research Network, Albuquerque, NM, USA
    Neuropsychopharmacology 36:1359-65. 2011
  2. pmc Impaired secondary somatosensory gating in patients with schizophrenia
    Robert J Thoma
    Department of Psychiatry, University of New Mexico School of Medicine, Albuquerque, NM 87131 0001, USA
    Psychiatry Res 151:189-99. 2007
  3. pmc Hippocampus volume and episodic memory in schizophrenia
    Robert J Thoma
    Department of Psychiatry, University of New Mexico School of Medicine, Albuquerque, USA
    J Int Neuropsychol Soc 15:182-95. 2009
  4. ncbi request reprint Developmental instability and the neural dynamics of the speed-intelligence relationship
    Robert J Thoma
    Center for Neuropsychological Services, Department of Psychiatry, 915 Vassar NE, 1 University of New Mexico, Albuquerque, NM 87131 0001, USA
    Neuroimage 32:1456-64. 2006
  5. ncbi request reprint Neuropsychological and sensory gating deficits related to remote alcohol abuse history in schizophrenia
    Robert J Thoma
    Department of Psychiatry, University of New Mexico School of Medicine, Albuquerque, New Mexico 87131 0001, USA
    J Int Neuropsychol Soc 12:34-44. 2006
  6. pmc Schizophrenia diagnosis and anterior hippocampal volume make separate contributions to sensory gating
    Robert J Thoma
    Department of Psychiatry, University of New Mexico, Albuquerque, New Mexico 87131 0001, USA
    Psychophysiology 45:926-35. 2008
  7. pmc Adolescent substance abuse: the effects of alcohol and marijuana on neuropsychological performance
    Robert J Thoma
    Department of Psychiatry, University of New Mexico, Albuquerque, 87131, USA
    Alcohol Clin Exp Res 35:39-46. 2011
  8. ncbi request reprint Lateralization of auditory sensory gating and neuropsychological dysfunction in schizophrenia
    Robert J Thoma
    Psychiatry Service, Department of Radiology, New Mexico VA Health Care System, VAMC 116A, 1501 San Pedro SE, Albuquerque, NM 87108, USA
    Am J Psychiatry 160:1595-605. 2003
  9. ncbi request reprint Visual processing of facial affect
    Stephen Lewis
    Department of Psychiatry, University of New Mexico, School of Medicine, Albuquerque, NM 87131, USA
    Neuroreport 14:1841-5. 2003
  10. pmc Cognitive abilities and 50- and 100-msec paired-click processes in schizophrenia
    Ashley K Smith
    Center for Functional Brain Imaging, New Mexico VA Health Care System, 1501 San Pedro Drive S E, Albuquerque, NM 87108, USA
    Am J Psychiatry 167:1264-75. 2010

Research Grants

Collaborators

Detail Information

Publications23

  1. pmc Perturbation of the glutamate-glutamine system in alcohol dependence and remission
    Robert Thoma
    MIND Research Network, Albuquerque, NM, USA
    Neuropsychopharmacology 36:1359-65. 2011
    ..The absence of differences in mean Glu and Gln between the AUD and AUD-R groups suggests that altered Glu-Gln metabolism may either predate the onset of abuse or persist during prolonged abstinence...
  2. pmc Impaired secondary somatosensory gating in patients with schizophrenia
    Robert J Thoma
    Department of Psychiatry, University of New Mexico School of Medicine, Albuquerque, NM 87131 0001, USA
    Psychiatry Res 151:189-99. 2007
    ..Patients demonstrated no impairment in SI gating, but a robust gating deficit in SII, supporting the presence of cross modal gating deficits in schizophrenia...
  3. pmc Hippocampus volume and episodic memory in schizophrenia
    Robert J Thoma
    Department of Psychiatry, University of New Mexico School of Medicine, Albuquerque, USA
    J Int Neuropsychol Soc 15:182-95. 2009
    ..In this sample of adults with schizophrenia, atypical relationships between regional hippocampus volumes and episodic memory ability were found, as was an atypical negative association between hippocampus volume and age...
  4. ncbi request reprint Developmental instability and the neural dynamics of the speed-intelligence relationship
    Robert J Thoma
    Center for Neuropsychological Services, Department of Psychiatry, 915 Vassar NE, 1 University of New Mexico, Albuquerque, NM 87131 0001, USA
    Neuroimage 32:1456-64. 2006
    ..These observations suggest that fluid intelligence is primarily related to speed during processing associated with decision time, while fluctuating asymmetry predicted slower processing across all stages of information processing...
  5. ncbi request reprint Neuropsychological and sensory gating deficits related to remote alcohol abuse history in schizophrenia
    Robert J Thoma
    Department of Psychiatry, University of New Mexico School of Medicine, Albuquerque, New Mexico 87131 0001, USA
    J Int Neuropsychol Soc 12:34-44. 2006
    ....
  6. pmc Schizophrenia diagnosis and anterior hippocampal volume make separate contributions to sensory gating
    Robert J Thoma
    Department of Psychiatry, University of New Mexico, Albuquerque, New Mexico 87131 0001, USA
    Psychophysiology 45:926-35. 2008
    ..Schizophrenia diagnosis predicted M50 gating independent of hippocampal volume. These results are consistent with the finding that hippocampus is a critical part of a fronto-temporal circuit involved in auditory gating...
  7. pmc Adolescent substance abuse: the effects of alcohol and marijuana on neuropsychological performance
    Robert J Thoma
    Department of Psychiatry, University of New Mexico, Albuquerque, 87131, USA
    Alcohol Clin Exp Res 35:39-46. 2011
    ....
  8. ncbi request reprint Lateralization of auditory sensory gating and neuropsychological dysfunction in schizophrenia
    Robert J Thoma
    Psychiatry Service, Department of Radiology, New Mexico VA Health Care System, VAMC 116A, 1501 San Pedro SE, Albuquerque, NM 87108, USA
    Am J Psychiatry 160:1595-605. 2003
    ....
  9. ncbi request reprint Visual processing of facial affect
    Stephen Lewis
    Department of Psychiatry, University of New Mexico, School of Medicine, Albuquerque, NM 87131, USA
    Neuroreport 14:1841-5. 2003
    ..These findings are considered in the context of a specialized neural face-dependent information system...
  10. pmc Cognitive abilities and 50- and 100-msec paired-click processes in schizophrenia
    Ashley K Smith
    Center for Functional Brain Imaging, New Mexico VA Health Care System, 1501 San Pedro Drive S E, Albuquerque, NM 87108, USA
    Am J Psychiatry 167:1264-75. 2010
    ..In addition, the functional implications remain unclear. In the present study, EEG and magnetoencephalography (MEG) were used to examine paired-click measures and cognitive correlates of paired-click activity...
  11. ncbi request reprint A specific test of hippocampal deficit in schizophrenia
    Faith M Hanlon
    Department of Psychiatry, New Mexico Veterans Affairs Health Care System, University of New Mexico, Albuquerque, NM 87131, USA
    Behav Neurosci 119:863-75. 2005
    ..Patients' abnormal hippocampal lateralization may play a role in the hippocampal-dependent behavioral deficit...
  12. pmc Resting state and task-induced deactivation: A methodological comparison in patients with schizophrenia and healthy controls
    Maggie V Mannell
    The MIND Research Network, Albuquerque, New Mexico, USA
    Hum Brain Mapp 31:424-37. 2010
    ..The increased posterior and reduced anterior connectivity may partially explain some of the cognitive dysfunction and clinical symptoms that are frequently associated with schizophrenia...
  13. ncbi request reprint Efficacy of olanzapine and risperidone in schizophrenia: a randomized double-blind crossover design
    Jose M Canive
    Psychiatry Service, New Mexico VA Health Care System, Albuquerque, NM 87108, USA
    Psychopharmacol Bull 39:105-16. 2006
    ..Despite the small number of subjects, this study shows the potential of a within-subject design to elucidate differences in efficacy...
  14. ncbi request reprint Dynamic neural activity recorded from human amygdala during fear conditioning using magnetoencephalography
    Sandra N Moses
    Department of Psychology, University of New Mexico, Albuquerque, NM 87109, USA
    Brain Res Bull 71:452-60. 2007
    ..The amygdala also shows stimulus omission-related activation that could potentially provide feedback about experienced stimulus contingencies to modify future responding during learning and extinction...
  15. pmc The impact of developmental instability on Voxel-Based Morphometry analyses of neuroanatomical abnormalities in schizophrenia
    Matthew Euler
    Department of Psychology, University of New Mexico, Albuquerque, NM 87131, USA
    Schizophr Res 115:1-7. 2009
    ..These results support the DI approach and suggest that the unique etiologic factors associated with schizophrenia lead to widespread gray matter volume reductions...
  16. ncbi request reprint Distinct M50 and M100 auditory gating deficits in schizophrenia
    Faith M Hanlon
    Center for Functional Brain Imaging, New Mexico VA Health Care System, Albuquerque, New Mexico 87108, USA
    Psychophysiology 42:417-27. 2005
    ..In contrast, a right-hemisphere M100 gating deficit was unrelated to M50 gating in either hemisphere. Investigations of interhemisphere gating relations may clarify group differences in regional connectivity and their role in gating...
  17. ncbi request reprint Impairment on the hippocampal-dependent virtual Morris water task in schizophrenia
    Faith M Hanlon
    The Mental Illness and Neuroscience Discovery MIND Institute, 1101 Yale Blvd NE, Albuquerque, New Mexico 87106, USA
    Schizophr Res 87:67-80. 2006
    ..There was no deficit in the visible-platform condition. These findings identify a behavioral impairment on a hippocampal-dependent task in schizophrenia and support using the MWT in testing animal models of schizophrenia...
  18. ncbi request reprint Abnormal stimulus-response intensity functions in posttraumatic stress disorder: an electrophysiological investigation
    Jeffrey David Lewine
    Departments of Psychology and Psychiatry, University of New Mexico, Albuquerque, NM, USA
    Am J Psychiatry 159:1689-95. 2002
    ....
  19. pmc Superior temporal gyrus spectral abnormalities in schizophrenia
    J Christopher Edgar
    Department of Psychology, Beckman Institute Biomedical Imaging Center, University of Illinois at Urbana Champaign, Urbana, Illinois, USA
    Psychophysiology 45:812-24. 2008
    ..Compared to controls, patients with schizophrenia showed more low-frequency phase variability, and the decreased 100-ms S1 evoked response observed in patients was best predicted by the STG phase-locking measure...
  20. ncbi request reprint A parietal-frontal network studied by somatosensory oddball MEG responses, and its cross-modal consistency
    Ming Xiong Huang
    Department of Radiology, University of California, San Diego, 92103 8756, USA
    Neuroimage 28:99-114. 2005
    ....
  21. ncbi request reprint M50 sensory gating predicts negative symptoms in schizophrenia
    Robert J Thoma
    Psychiatry Service, New Mexico VA Health Care System, Albuquerque, NM 87108, United States
    Schizophr Res 73:311-8. 2005
    ..This finding is compatible with information processing theories of negative symptoms and with more recent findings of fronto-temporal abnormality in patients with predominantly negative symptoms...
  22. ncbi request reprint Cross-modal generality of the gating deficit
    J Christopher Edgar
    Department of Psychology and Beckman Institute Biomedical Imaging Center, University of Illinois at Urbana Champaign, Urbana, IL 61820, USA
    Psychophysiology 42:318-27. 2005
    ..Patients showed abnormal auditory M50 gating but normal somatosensory M20 gating. Results argue against a cross-modal gating deficit in primary somatosensory cortex...
  23. ncbi request reprint A non-invasive method for observing hippocampal function
    Faith M Hanlon
    New Mexico VA Health Care System, 1501 San Pedro Drive, SE Albuquerque, NM 87108, USA
    Neuroreport 14:1957-60. 2003
    ..Patients with unilateral hippocampal damage showed activation in undamaged hippocampus. MEG during transverse patterning performance is a promising, non-invasive tool for assessing hippocampal function...

Research Grants4

  1. Brain and Behavioral Impairment in Alcohol Dependence and Schizophrenia
    Robert Thoma; Fiscal Year: 2007
    ..It is relevant public health research in that it will help to develop new tools and biomarkers sensitive to alcohol-related cognitive dysfunction, and will expand our knowledge of cognitive recovery. ..
  2. Adolescent Neurodevelopment and Alcohol
    Robert Thoma; Fiscal Year: 2007
    ..This interdisciplinary project closely follows the guidelines set out in the 2005 NIH Roadmap. ..