Michael E Thase

Summary

Affiliation: University of Pittsburgh
Country: USA

Publications

  1. pmc Depression and sleep: pathophysiology and treatment
    Michael E Thase
    University of Pittsburgh Medical Center, PA, USA
    Dialogues Clin Neurosci 8:217-26. 2006
  2. ncbi request reprint Remission rates following antidepressant therapy with bupropion or selective serotonin reuptake inhibitors: a meta-analysis of original data from 7 randomized controlled trials
    Michael E Thase
    Department of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, PA 15213 2593, USA
    J Clin Psychiatry 66:974-81. 2005
  3. ncbi request reprint Correlates and consequences of chronic insomnia
    Michael E Thase
    Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, PA 15213 2593, USA
    Gen Hosp Psychiatry 27:100-12. 2005
  4. ncbi request reprint Cognitive therapy versus medication in augmentation and switch strategies as second-step treatments: a STAR*D report
    Michael E Thase
    Department of Psychiatry, University of Pittsburgh Medical Center, 3811 OHara St, Pittsburgh, PA 15213 2593, and Massachusetts General Hospital, USA
    Am J Psychiatry 164:739-52. 2007
  5. ncbi request reprint Introduction: new directions in the treatment of atypical depression
    Michael E Thase
    Department of Psychiatry, University of Pittsburgh Medical Center School of Medicine, and the Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, USA
    J Clin Psychiatry 68:4-9. 2007
  6. ncbi request reprint A randomized, double-blind comparison of olanzapine/fluoxetine combination, olanzapine, and fluoxetine in treatment-resistant major depressive disorder
    Michael E Thase
    Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    J Clin Psychiatry 68:224-36. 2007
  7. ncbi request reprint Relative antidepressant efficacy of venlafaxine and SSRIs: sex-age interactions
    Michael E Thase
    Department of Psychiatry, University of Pittsburgh Medical Center, Western Psychiatric Institute and Clinic, 3811 O Hara Street, Pittsburgh, PA 15213 2593, USA
    J Womens Health (Larchmt) 14:609-16. 2005
  8. ncbi request reprint Bipolar depression: issues in diagnosis and treatment
    Michael E Thase
    Department of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Harv Rev Psychiatry 13:257-71. 2005
  9. ncbi request reprint The failure of evidence-based medicine to guide treatment of antidepressant nonresponders
    Michael E Thase
    University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    J Clin Psychiatry 67:1833-5. 2006
  10. ncbi request reprint Preventing relapse and recurrence of depression: a brief review of therapeutic options
    Michael E Thase
    Department of Psychiatry, University of Pittsburgh Medical Center, Pennsylvania 15213 2593, USA
    CNS Spectr 11:12-21. 2006

Collaborators

Detail Information

Publications102 found, 100 shown here

  1. pmc Depression and sleep: pathophysiology and treatment
    Michael E Thase
    University of Pittsburgh Medical Center, PA, USA
    Dialogues Clin Neurosci 8:217-26. 2006
    ..Cognitive behavioral therapy and other nonpharmacologic strategies are also helpful...
  2. ncbi request reprint Remission rates following antidepressant therapy with bupropion or selective serotonin reuptake inhibitors: a meta-analysis of original data from 7 randomized controlled trials
    Michael E Thase
    Department of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, PA 15213 2593, USA
    J Clin Psychiatry 66:974-81. 2005
    ....
  3. ncbi request reprint Correlates and consequences of chronic insomnia
    Michael E Thase
    Department of Psychiatry, Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, PA 15213 2593, USA
    Gen Hosp Psychiatry 27:100-12. 2005
    ..New and emerging anti-insomnia agents may prove useful in the long-term treatment of chronic insomnia. Further research is needed to establish the benefits of such treatment...
  4. ncbi request reprint Cognitive therapy versus medication in augmentation and switch strategies as second-step treatments: a STAR*D report
    Michael E Thase
    Department of Psychiatry, University of Pittsburgh Medical Center, 3811 OHara St, Pittsburgh, PA 15213 2593, and Massachusetts General Hospital, USA
    Am J Psychiatry 164:739-52. 2007
    ..Cognitive therapy was compared with medication augmentation and switch strategies...
  5. ncbi request reprint Introduction: new directions in the treatment of atypical depression
    Michael E Thase
    Department of Psychiatry, University of Pittsburgh Medical Center School of Medicine, and the Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, USA
    J Clin Psychiatry 68:4-9. 2007
  6. ncbi request reprint A randomized, double-blind comparison of olanzapine/fluoxetine combination, olanzapine, and fluoxetine in treatment-resistant major depressive disorder
    Michael E Thase
    Western Psychiatric Institute and Clinic, University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    J Clin Psychiatry 68:224-36. 2007
    ..Two parallel, 8-week double-blind studies compared olanzapine/fluoxetine combination, olanzapine, and fluoxetine in outpatients with treatment-resistant depression (TRD)...
  7. ncbi request reprint Relative antidepressant efficacy of venlafaxine and SSRIs: sex-age interactions
    Michael E Thase
    Department of Psychiatry, University of Pittsburgh Medical Center, Western Psychiatric Institute and Clinic, 3811 O Hara Street, Pittsburgh, PA 15213 2593, USA
    J Womens Health (Larchmt) 14:609-16. 2005
    ..To investigate whether differences in antidepressant efficacy are moderated by an interaction of age and gender...
  8. ncbi request reprint Bipolar depression: issues in diagnosis and treatment
    Michael E Thase
    Department of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Harv Rev Psychiatry 13:257-71. 2005
    ..The optimal duration of maintenance antidepressant therapy has not been established empirically and, until better evidence-based guidelines are established, should be determined on a case-by-case basis...
  9. ncbi request reprint The failure of evidence-based medicine to guide treatment of antidepressant nonresponders
    Michael E Thase
    University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    J Clin Psychiatry 67:1833-5. 2006
  10. ncbi request reprint Preventing relapse and recurrence of depression: a brief review of therapeutic options
    Michael E Thase
    Department of Psychiatry, University of Pittsburgh Medical Center, Pennsylvania 15213 2593, USA
    CNS Spectr 11:12-21. 2006
    ....
  11. ncbi request reprint Efficacy of quetiapine monotherapy in bipolar I and II depression: a double-blind, placebo-controlled study (the BOLDER II study)
    Michael E Thase
    Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, Pittsburgh, PA 15213 2593, USA
    J Clin Psychopharmacol 26:600-9. 2006
    ..This study demonstrates that quetiapine monotherapy is an effective and well-tolerated treatment for depressive episodes in bipolar disorder, confirming the results observed from a previous study (BipOLar DEpRession [BOLDER] I)...
  12. ncbi request reprint Managing depressive and anxiety disorders with escitalopram
    Michael E Thase
    University of Pittsburgh Medical Centre, Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213 2593, USA
    Expert Opin Pharmacother 7:429-40. 2006
    ..Pharmacoeconomic models suggest that the greater drug acquisition cost of this patent-protected compound may be offset by greater efficacy (relative to generic citalopram) and tolerability (compared with extended release venlafaxine)...
  13. ncbi request reprint Modafinil augmentation of SSRI therapy in patients with major depressive disorder and excessive sleepiness and fatigue: a 12-week, open-label, extension study
    Michael E Thase
    Division of Adult Academic Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, PA, USA
    CNS Spectr 11:93-102. 2006
    ..Placebo-controlled studies indicate that modafinil, a wake-promoting agent, may relieve residual symptoms...
  14. ncbi request reprint Treatment of anxiety disorders with venlafaxine XR
    Michael E Thase
    University of Pittsburgh Medical Center, Pittsburgh, PA 15213, USA
    Expert Rev Neurother 6:269-82. 2006
    ..Concerns about safety in overdose have also recently emerged. Despite these caveats, venlafaxine XR is an effective and generally well-tolerated option for treatment of anxiety disorders...
  15. ncbi request reprint Pharmacotherapy of bipolar depression: an update
    Michael E Thase
    University of Pittsburgh Medical Center, Western Psychiatric Institute and Clinic, 3811 O Hara St, Pittsburgh, PA 15213 2593, USA
    Curr Psychiatry Rep 8:478-88. 2006
    ..Antidepressants--particularly selective serotonin reuptake inhibitors and bupropion--are indicated when mood stabilizers are ineffective and for "breakthrough" depressions...
  16. ncbi request reprint Treatment with venlafaxine extended release after SSRI nonresponse or intolerance: a randomized comparison of standard- and higher-dosing strategies
    Michael E Thase
    University of Pittsburgh Medical Center, Department of Psychiatry, Pittsburgh, PA 15213 2593, USA
    J Clin Psychopharmacol 26:250-8. 2006
    ....
  17. ncbi request reprint Introduction: the dual-action debate: does pharmacology matter?
    Michael E Thase
    Department of Psychiatry, University of Pittsburgh Medical Center, 3811 O Hara St, Pittsburgh, PA 15213 2593, USA
    J Clin Psychiatry 65:3-4. 2004
  18. ncbi request reprint Therapeutic alternatives for difficult-to-treat depression: a narrative review of the state of the evidence
    Michael E Thase
    Department of Psychiatry, University of Pittsburgh Medical Center, Pittsburgh, PA 15213 2593, USA
    CNS Spectr 9:808-16, 818-21. 2004
    ....
  19. ncbi request reprint Treatment of recurrent depression: an alternate viewpoint
    Michael E Thase
    University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania, USA
    CNS Drugs 17:1119-22. 2003
  20. ncbi request reprint Bipolar depression: diagnostic and treatment considerations
    Michael E Thase
    Western Psychiatric Institute and Clinic, University of Pittsburgh Medical Center, PA 15123 2593, USA
    Dev Psychopathol 18:1213-30. 2006
    ..Studies of adults indicate that several forms of focused psychotherapy may improve longer term outcomes...
  21. ncbi request reprint Acceptability of second-step treatments to depressed outpatients: a STAR*D report
    Stephen R Wisniewski
    Department of Psychiatry, Epidemiology Data Center, Graduate School of Public Health, University of Pittsburgh, Pittsburgh, PA 15261, and Clinical Psychopharmacology Unit, Massachusetts General Hospital, Boston, USA
    Am J Psychiatry 164:753-60. 2007
    ..This study sought to identify factors that affect patients' willingness to accept different second-step treatment approaches...
  22. doi request reprint Income and attrition in the treatment of depression: a STAR*D report
    Diane Warden
    Department of Psychiatry, The University of Texas Southwestern Medical Center at Dallas, Dallas, Texas 75390 9086, USA
    Depress Anxiety 26:622-33. 2009
    ..This report assessed whether attrition rates and predictors of attrition differed among depressed outpatients with different income levels...
  23. doi request reprint What predicts attrition in second step medication treatments for depression?: a STAR*D Report
    Diane Warden
    Department of Psychiatry, The University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390 9119, USA
    Int J Neuropsychopharmacol 12:459-73. 2009
    ..Focus on patients with attrition risk factors for medication augmentation or switch strategies may enhance retention and improve outcomes...
  24. ncbi request reprint Depressive illness burden associated with complex polypharmacy in patients with bipolar disorder: findings from the STEP-BD
    Joseph F Goldberg
    Department of Psychiatry, Mount Sinai School of Medicine, New York, NY, USA
    J Clin Psychiatry 70:155-62. 2009
    ..Many patients with bipolar disorder receive multi-drug treatment regimens, but the distinguishing profiles of patients who receive complex pharmacologies have not been established...
  25. ncbi request reprint Sequenced treatment alternatives to relieve depression (STAR*D): rationale and design
    A John Rush
    Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9086, USA
    Control Clin Trials 25:119-42. 2004
    ..Participants with an adequate symptomatic response may enter the 12-month naturalistic follow-up phase with brief monthly and more complete quarterly assessments...
  26. ncbi request reprint Randomized, placebo-controlled trial of nefazodone maintenance treatment in preventing recurrence in chronic depression
    Alan J Gelenberg
    Department of Psychiatry, Health Sciences Center, University of Arizona, PO Box 245002, Tucson, AZ 85724 5002, USA
    Biol Psychiatry 54:806-17. 2003
    ..This randomized, placebo-controlled study of the efficacy and safety of nefazodone in preventing recurrence was conducted for patients with chronic MDD...
  27. ncbi request reprint Medication augmentation after the failure of SSRIs for depression
    Madhukar H Trivedi
    Mood Disorder Program and Clinic, Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX 75390 9119, USA
    N Engl J Med 354:1243-52. 2006
    ..Although clinicians frequently add a second medication to an initial, ineffective antidepressant drug, no randomized controlled trial has compared the efficacy of this approach...
  28. ncbi request reprint Acute and longer-term outcomes in depressed outpatients requiring one or several treatment steps: a STAR*D report
    A John Rush
    Department of Psychiatry, University of Texas Southwestern Medical Center at Dallas, 5323 Harry Hines Blvd, Dallas, TX 75390 9086, USA
    Am J Psychiatry 163:1905-17. 2006
    ..This report describes the participants and compares the acute and longer-term treatment outcomes associated with each of four successive steps in the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) trial...
  29. ncbi request reprint Prevention of recurrent episodes of depression with venlafaxine ER in a 1-year maintenance phase from the PREVENT Study
    James H Kocsis
    Department of Psychiatry, Weill Cornell Medical College, New York, NY 10012, USA
    J Clin Psychiatry 68:1014-23. 2007
    ..To test the long-term efficacy and safety of venlafaxine extended-release (ER) in preventing recurrence in patients with major depression...
  30. pmc Which symptoms predict recurrence of depression in women treated with maintenance interpersonal psychotherapy?
    Alexandre Y Dombrovski
    Western Psychiatric Institute and Clinic, Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA
    Depress Anxiety 25:1060-6. 2008
    ..We therefore examined the impact of persistent symptoms, including mood, insomnia, and anxiety symptoms, on time to recurrence in women receiving maintenance interpersonal psychotherapy (IPT-M) for recurrent depression...
  31. doi request reprint Can phase III trial results of antidepressant medications be generalized to clinical practice? A STAR*D report
    Stephen R Wisniewski
    Epidemiology Data Center, Graduate School of Public Health, University of Pittsburgh, 127 Parran Hall, 130 DeSoto St, Pittsburgh, PA 15261, USA
    Am J Psychiatry 166:599-607. 2009
    ....
  32. doi request reprint Clinical features associated with poor pharmacologic adherence in bipolar disorder: results from the STEP-BD study
    Roy H Perlis
    Bipolar Clinic and Research Program, Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    J Clin Psychiatry 71:296-303. 2010
    ..Poor medication adherence is common among bipolar patients...
  33. ncbi request reprint An integrated analysis of olanzapine/fluoxetine combination in clinical trials of treatment-resistant depression
    Madhukar H Trivedi
    Department of Psychiatry, University of Texas Southwestern Medical Center at Dallas, Dallas, TX 75390 9119, USA
    J Clin Psychiatry 70:387-96. 2009
    ..To evaluate the efficacy of olanzapine/fluoxetine combination (OFC) versus olanzapine or fluoxetine monotherapy across all clinical trials of treatment-resistant depression sponsored by Eli Lilly and Company...
  34. doi request reprint Clinical correlates of the worsening or emergence of suicidal ideation during SSRI treatment of depression: an examination of citalopram in the STAR*D study
    Sidney Zisook
    Department of Psychiatry, University of California, San Diego, San Diego VA Medical Center, San Diego, California, USA
    J Affect Disord 117:63-73. 2009
    ..The purpose of this study was to determine whether, and in whom, treatment of MDD is associated with increased or emergent SI...
  35. pmc Cognitive behavioral analysis system of psychotherapy and brief supportive psychotherapy for augmentation of antidepressant nonresponse in chronic depression: the REVAMP Trial
    James H Kocsis
    Department of Psychiatry, Weill Cornell Medical College, 1300 York Ave, New York, NY 10065, USA
    Arch Gen Psychiatry 66:1178-88. 2009
    ..Previous studies have found that few chronically depressed patients remit with antidepressant medications alone...
  36. ncbi request reprint Randomized, placebo-controlled trial of fluoxetine for acute treatment of minor depressive disorder
    Lewis L Judd
    Department of Psychiatry, University of California, San Diego, 9500 Gilman Dr, La Jolla, CA 92093 0603, USA
    Am J Psychiatry 161:1864-71. 2004
    ..Minor depressive disorder is both common and associated with significant psychosocial impairment. This study examined antidepressant treatment efficacy in a large group of patients with minor depressive disorder...
  37. pmc Primary versus specialty care outcomes for depressed outpatients managed with measurement-based care: results from STAR*D
    Bradley N Gaynes
    Department of Psychiatry, University of North Carolina School of Medicine, Chapel Hill, NC, USA
    J Gen Intern Med 23:551-60. 2008
    ..Whether the acute outcomes of major depressive disorder (MDD) treated in primary (PC) or specialty care (SC) settings are different is unknown...
  38. ncbi request reprint Bupropion-SR, sertraline, or venlafaxine-XR after failure of SSRIs for depression
    A John Rush
    Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX 75390 9086, USA
    N Engl J Med 354:1231-42. 2006
    ..After unsuccessful treatment for depression with a selective serotonin-reuptake inhibitor (SSRI), it is not known whether switching to one antidepressant is more effective than switching to another...
  39. doi request reprint The prospective course of rapid-cycling bipolar disorder: findings from the STEP-BD
    Christopher D Schneck
    Department of Psychiatry, University of Colorado Health Sciences Center, Denver, CO 80220, USA
    Am J Psychiatry 165:370-7; quiz 410. 2008
    ..In a naturalistic follow-up of adult bipolar patients, the authors examined the contributions of demographic, phenomenological, and clinical variables, including antidepressant use, to prospectively observed mood episode frequency...
  40. pmc Bipolar disorder center for Pennsylvanians: implementing an effectiveness trial to improve treatment for at-risk patients
    David J Kupfer
    Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, 3811 O Hara St, Pittsburgh, PA 15213, USA
    Psychiatr Serv 60:888-97. 2009
    ..This report highlights the methods used to recruit, screen, and enroll a cohort of difficult-to-recruit individuals with bipolar disorder...
  41. ncbi request reprint Sexual function and satisfaction in the treatment of chronic major depression with nefazodone, psychotherapy, and their combination
    John Zajecka
    Department of Psychiatry, Rush Presbyterian St Luke s Medical Center, 1725 W Harrison Street, Suite 955, Chicago, IL 60612, USA
    J Clin Psychiatry 63:709-16. 2002
    ..This study compares the effects of antidepressant medication, psychotherapy, and combined treatment on sexual interest/satisfaction and function in patients with chronic major depression...
  42. ncbi request reprint Differential effects of nefazodone and cognitive behavioral analysis system of psychotherapy on insomnia associated with chronic forms of major depression
    Michael E Thase
    Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, PA 15213 2593, USA
    J Clin Psychiatry 63:493-500. 2002
    ..As nefazodone-mediated blockade of serotonin-2 receptors may directly relieve insomnia associated with depression, we examined the more specific effects of CBASP and nefazodone, singly and in combination, on sleep disturbances...
  43. pmc Chronic forms of major depression are still undertreated in the 21st century: systematic assessment of 801 patients presenting for treatment
    James H Kocsis
    Department of Psychiatry, Weill Cornell Medical Center, 525 East 68th Street, New York, NY 10021, USA
    J Affect Disord 110:55-61. 2008
    ..These results and the consistency of similar results over time point to the dire need for patient and provider education regarding the signs and symptoms of depression and its treatment...
  44. ncbi request reprint Self-reported depressive symptom measures: sensitivity to detecting change in a randomized, controlled trial of chronically depressed, nonpsychotic outpatients
    A John Rush
    Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX 75390 9086, USA
    Neuropsychopharmacology 30:405-16. 2005
    ..Global patient ratings such as the PGI-I, as opposed to specific item-based ratings, provide less valid findings...
  45. pmc Insomnia and objectively measured sleep disturbances predict treatment outcome in depressed patients treated with psychotherapy or psychotherapy-pharmacotherapy combinations
    Wendy M Troxel
    Department of Psychiatry and Psychology, University of Pittsburgh, Pittsburgh, PA 15213, USA
    J Clin Psychiatry 73:478-85. 2012
    ..The present study is a secondary analysis that examines the degree to which insomnia, objective sleep disturbances, or their combination predicts depression remission following pharmacotherapy and/or psychotherapy treatment...
  46. ncbi request reprint Does recovery from substance use disorder matter in patients with bipolar disorder?
    Roger D Weiss
    Department of Psychiatry, Harvard Medical School, Boston, USA
    J Clin Psychiatry 66:730-5; quiz 808-9. 2005
    ..To examine the potential impact of recovery from substance use disorder (SUD) on the course of bipolar disorder among patients diagnosed with both bipolar and substance use disorders according to DSM-IV criteria...
  47. doi request reprint Differential effects of treatments for chronic depression: a latent growth model reanalysis
    Niklaus Stulz
    Department of Psychiatry, University of Pennsylvania Philadelphia, PA 19104, USA
    J Consult Clin Psychol 78:409-19. 2010
    ....
  48. doi request reprint Sustained gamma-band EEG following negative words in depression and schizophrenia
    Greg J Siegle
    University of Pittsburgh School of Medicine, Pittsburgh, PA, USA
    Int J Psychophysiol 75:107-18. 2010
    ..This study examined whether there were group differences in baseline and sustained gamma-band EEG following emotional stimuli in healthy adults as well as adults with depression and schizophrenia...
  49. doi request reprint Lithium treatment -- moderate dose use study (LiTMUS) for bipolar disorder: rationale and design
    Andrew A Nierenberg
    Department of Psychiatry, Massachusetts General Hospital, Boston, MA 02114, USA
    Clin Trials 6:637-48. 2009
    ..Recent data indicate that lithium use for bipolar disorder has declined over the last decade and that lithium largely has been replaced with alternate, commercially promoted medications that may or may not result in better outcomes...
  50. ncbi request reprint REVAMP - Research Evaluating the Value of Augmenting Medication with Psychotherapy: rationale and design
    Madhukar H Trivedi
    Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX, USA
    Psychopharmacol Bull 41:5-33. 2008
    ....
  51. ncbi request reprint Two-year outcomes for interpersonal and social rhythm therapy in individuals with bipolar I disorder
    Ellen Frank
    Western Psychiatric Institute and Clinic, Department of Psychiatry, University of Pittsburgh School of Medicine, Pittsburgh, PA 15213, USA
    Arch Gen Psychiatry 62:996-1004. 2005
    ..Recent investigations have demonstrated benefits from the addition of psychoeducation or psychotherapy to pharmacotherapy in this population...
  52. ncbi request reprint Patient preference as a moderator of outcome for chronic forms of major depressive disorder treated with nefazodone, cognitive behavioral analysis system of psychotherapy, or their combination
    James H Kocsis
    Department of Psychiatry, Weill Cornell Medical College, New York, N Y, USA
    J Clin Psychiatry 70:354-61. 2009
    ..We hypothesized that patient preference at baseline would interact with treatment group to differentially affect treatment outcome...
  53. pmc Association study of 21 circadian genes with bipolar I disorder, schizoaffective disorder, and schizophrenia
    Hader A Mansour
    Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, USA
    Bipolar Disord 11:701-10. 2009
    ..The results are plausible, based on prior studies of circadian abnormalities. As replications have not been attempted uniformly, we evaluated representative, common polymorphisms in all three disorders...
  54. ncbi request reprint Effect of age at onset on the course of major depressive disorder
    Sidney Zisook
    Department of Psychiatry, University of California, San Diego, CA 92093, USA
    Am J Psychiatry 164:1539-46. 2007
    ..This report assesses whether age at onset defines a specific subgroup of major depressive disorder in 4,041 participants who entered the Sequenced Treatment Alternatives to Relieve Depression (STAR*D) study...
  55. ncbi request reprint Clinical significance of lifetime panic spectrum symptoms in the treatment of patients with bipolar I disorder
    Ellen Frank
    Department of Psychiatry, Western Psychiatric Institute and Clinic, Pittsburgh, PA 15213, USA
    Arch Gen Psychiatry 59:905-11. 2002
    ..We hypothesized that lifetime panic spectrum features would be associated with higher levels of suicidal ideation and a poorer response to acute treatment of the index mood episode in this patient population...
  56. ncbi request reprint Background and rationale for the sequenced treatment alternatives to relieve depression (STAR*D) study
    Maurizio Fava
    Department of Psychiatry, Massachusetts General Hospital, Boston, MA, USA
    Psychiatr Clin North Am 26:457-94, x. 2003
    ..This article provides the overall rationale for STAR*D and details the rationale for key design, measurement, and analytic features of the study...
  57. ncbi request reprint The 16-Item Quick Inventory of Depressive Symptomatology (QIDS), clinician rating (QIDS-C), and self-report (QIDS-SR): a psychometric evaluation in patients with chronic major depression
    A John Rush
    Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9086, USA
    Biol Psychiatry 54:573-83. 2003
    ..The QIDS-SR(16) has highly acceptable psychometric properties, which supports the usefulness of this brief rating of depressive symptom severity in both clinical and research settings...
  58. doi request reprint Update on partial response in depression
    Michael E Thase
    Department of Psychiatry, University of Pennsylvania School of Medicine, Philadelphia Veterans Affairs Medical Center, and Pittsburgh Medical Center, Philadelphia and Pittsburgh, USA
    J Clin Psychiatry 70:4-9. 2009
    ..Although studies on predictive factors have not yielded definitive results, clinicians in practice often select adjunctive agents that target patients' persistent symptoms...
  59. ncbi request reprint Report by the ACNP Task Force on response and remission in major depressive disorder
    A John Rush
    Department of Psychiatry, University of Texas Southwestern Medical Center, Dallas, TX 75390 9086, USA
    Neuropsychopharmacology 31:1841-53. 2006
    ..Research to evaluate these recommendations empirically is needed...
  60. ncbi request reprint A comparison of baseline sociodemographic and clinical characteristics between major depressive disorder patients with and without diabetes: a STAR*D report
    Charlene J Bryan
    School of Nursing, University of Pennsylvania, Philadelphia, Pennsylvania, USA
    J Affect Disord 108:113-20. 2008
    ....
  61. ncbi request reprint Validity of the distinction between primary and secondary substance use disorder in patients with bipolar disorder: data from the first 1000 STEP-BD participants
    Mark D Fossey
    Department of Psychiatry, University of Oklahoma College of Medicine Tulsa, Tulsa, Oklahoma 74135, USA
    Am J Addict 15:138-43. 2006
    ..The primary/secondary distinction for SUD is not valid when variations in the age of onset of the non-SUD are linked to course characteristics...
  62. ncbi request reprint Selecting appropriate treatments for maintenance therapy for bipolar disorder
    Michael E Thase
    Department of Psychiatry, University of Pennsylvania School of Medicine and Philadelphia Veterans Affairs Medical Center, Philadelphia, PA 19104, USA
    J Clin Psychiatry 69:28-35. 2008
    ..Additionally, several forms of psychotherapy specifically tailored to the needs of people with bipolar disorder should be considered as an adjunct to medication...
  63. ncbi request reprint Brief report: paroxetine in younger and adult individuals at high risk for suicide
    Mark S Bauer
    Department of Psychiatry, Brown University, USA
    Psychopharmacol Bull 39:31-7. 2006
    ..In fact, the younger group showed a trend for decreased suicidality (P = .13). Thus, increased suicidality risk with paroxetine exposure does not extend to this other high-risk mood disordered population, even among younger individuals...
  64. ncbi request reprint The state of knowledge of chronic depression
    Alan J Gelenberg
    Department of Psychiatry, Arizona Health Sciences Center, Tucson, AZ, USA
    J Clin Psychiatry 67:179-84. 2006
  65. ncbi request reprint Symptomatic and syndromal anxiety in chronic forms of major depression: effect of nefazodone, cognitive behavioral analysis system of psychotherapy, and their combination
    Philip T Ninan
    Department of Psychiatry, Emory University School of Medicine, Atlanta, GA 30329, USA
    J Clin Psychiatry 63:434-41. 2002
    ....
  66. ncbi request reprint Augmentation strategies for depression: history and concepts
    Michael E Thase
    University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    CNS Spectr 12:3-5. 2007
  67. ncbi request reprint Management of patients with treatment-resistant depression
    Michael E Thase
    Department of Psychiatry, University of Pittsburgh Medical Center, Western Psychiatric Institute and Clinic, Pittsburgh, PA, USA
    J Clin Psychiatry 69:e8. 2008
    ....
  68. ncbi request reprint Modafinil augmentation of selective serotonin reuptake inhibitor therapy in MDD partial responders with persistent fatigue and sleepiness
    Maurizio Fava
    Depression Clinical and Research Program, Massachusetts General Hospital, Boston, MA 02114, and Department of Psychiatry, University of Pittsburgh Medical Center, PA, USA
    Ann Clin Psychiatry 19:153-9. 2007
    ..This study evaluated modafinil in patients with major depressive disorder (MDD) who were partial responders to adequate selective serotonin reuptake inhibitor (SSRI) therapy and excessive sleepiness and fatigue...
  69. ncbi request reprint A double-blind comparison between bupropion XL and venlafaxine XR: sexual functioning, antidepressant efficacy, and tolerability
    Michael E Thase
    Department of Psychiatry, University of Pittsburgh Medical Center, Western Psychiatric Institute, Pittsburgh, PA, USA
    J Clin Psychopharmacol 26:482-8. 2006
    ..In conclusion, in this patient population (ie, relatively young, sexually active outpatients), bupropion XL was at least as effective as venlafaxine XR and had a significantly more favorable sexual side effect profile...
  70. ncbi request reprint Efficacy of duloxetine and selective serotonin reuptake inhibitors: comparisons as assessed by remission rates in patients with major depressive disorder
    Michael E Thase
    Department of Psychiatry, University of Pennsylvania School of Medicine, 3535 Market Street, Philadelphia, PA 19104, USA
    J Clin Psychopharmacol 27:672-6. 2007
    ....
  71. ncbi request reprint Electroencephalographic sleep profiles in single-episode and recurrent unipolar forms of major depression: II. Comparison during remission
    Ripu D Jindal
    Department of Psychiatry, University of Pittsburgh School of Medicine, Western Psychiatric Institute and Clinic, Pittsburgh, Pennsylvania 15213, USA
    Biol Psychiatry 51:230-6. 2002
    ..This study examines whether the observed differences in the sleep patterns during recurrent and single-episode depression persist into remission following nonpharmacologic treatment...
  72. doi request reprint A randomized, double-blind, placebo-controlled study of the effect of sustained-release bupropion on blood pressure in individuals with mild untreated hypertension
    Michael E Thase
    Department of Psychiatry, University of Pennsylvania School of Medicine, 3535 Market Street, Philadelphia, PA 19104, USA
    J Clin Psychopharmacol 28:302-7. 2008
    ..28 vs -0.64 beats/min; Delta = 2.92, P = 0.004). Although only minor effects on blood pressure were observed in this trial, an infrequent association of bupropion therapy and treatment-emergent hypertension cannot be ruled out...
  73. ncbi request reprint Focus on bipolar disorder treatment
    Charles L Bowden
    Department of Psychiatry, University of Texas Health Science Center at San Antonio, TX, USA
    J Clin Psychiatry 66:1598-609. 2005
  74. ncbi request reprint Persistent posttraumatic stress disorder following September 11 in patients with bipolar disorder
    Mark H Pollack
    Department of Psychiatry, Massachusetts General Hospital, Boston, Mass, USA
    J Clin Psychiatry 67:394-9. 2006
    ....
  75. doi request reprint Retrospective age at onset of bipolar disorder and outcome during two-year follow-up: results from the STEP-BD study
    Roy H Perlis
    Bipolar Clinical and Research Program, Department of Psychiatry, Massachusetts General Hospital and Harvard Medical School, ACC 812 15 Parkman Street, Boston, MA 02114, USA
    Bipolar Disord 11:391-400. 2009
    ..Symptoms of bipolar disorder are increasingly recognized among children and adolescents, but little is known about the course of bipolar disorder among adults who experience childhood onset of symptoms...
  76. ncbi request reprint Predictors of recurrence in bipolar disorder: primary outcomes from the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD)
    Roy H Perlis
    Bipolar Clinical and Research Program, Massachusetts General Hospital, ACC 812, 15 Parkman Street, Boston, MA 02114, USA
    Am J Psychiatry 163:217-24. 2006
    ..The authors looked for the features associated with risk of recurrence...
  77. ncbi request reprint Treatment-resistant bipolar depression: a STEP-BD equipoise randomized effectiveness trial of antidepressant augmentation with lamotrigine, inositol, or risperidone
    Andrew A Nierenberg
    Massachusetts General Hospital Bipolar Clinic and Research Program, Suite 580, 50 Staniford Street, Boston, MA 02114, USA
    Am J Psychiatry 163:210-6. 2006
    ..This study represents the first randomized trial of competing options for treatment-resistant bipolar depression and assesses the effectiveness and safety of antidepressant augmentation with lamotrigine, inositol, and risperidone...
  78. ncbi request reprint Placebo-controlled continuation treatment with mirtazapine: acute pattern of response predicts relapse
    Andrew A Nierenberg
    Havard Medical School, Massachusetts General Hospital, Boston, MA 02114, USA
    Neuropsychopharmacology 29:1012-8. 2004
    ..The low relapse rate for patients with an acute placebo pattern switched to placebo suggests specific drug effect played a smaller role in their initial improvement...
  79. ncbi request reprint Therapeutic alliance in depression treatment: controlling for prior change and patient characteristics
    Daniel N Klein
    Department of Psychology and Psychiatry, State University of New York at Stony Brook, 11794 2500, USA
    J Consult Clin Psychol 71:997-1006. 2003
    ..Patients receiving combination treatment reported stronger alliances with their psychotherapists than patients receiving CBASP alone. However, the impact of the alliance on outcome was similar for both treatment conditions...
  80. ncbi request reprint The effects of psychotherapy, nefazodone, and their combination on subjective assessment of disturbed sleep in chronic depression
    Rachel Manber
    Department of Psychiatry and Behavioral Sciences, Stanford University, CA 94305, USA
    Sleep 26:130-6. 2003
    ..The purpose of the study was to compare the effects of psychotherapy, nefazodone, and their combination on subjective measures of sleep in patients with chronic forms of major depression...
  81. ncbi request reprint Pharmacological Treatment Patterns at Study Entry for the First 500 STEP-BD Participants
    S Nassir Ghaemi
    Department of Psychiatry at Emory University in Atlanta, Georgia 30322, USA
    Psychiatr Serv 57:660-5. 2006
    ..This study assessed patterns of psychopharmacological treatment for bipolar disorder...
  82. ncbi request reprint Incidence of sexual side effects in refractory depression during treatment with citalopram or paroxetine
    Mikael Landen
    Section of Psychiatry St Göran, Department of Clinical Neuroscience, Karolinska Institutet, SE 112 81, Stockholm, Sweden
    J Clin Psychiatry 66:100-6. 2005
    ....
  83. ncbi request reprint Tranylcypromine versus venlafaxine plus mirtazapine following three failed antidepressant medication trials for depression: a STAR*D report
    Patrick J McGrath
    Depression Evaluation Service, New York State Psychiatric Institute, 1051 Riverside Dr, New York, NY 10032, USA
    Am J Psychiatry 163:1531-41; quiz 1666. 2006
    ....
  84. ncbi request reprint A comparison of lithium and T(3) augmentation following two failed medication treatments for depression: a STAR*D report
    Andrew A Nierenberg
    Massachusetts General Hospital, 50 Staniford St, Boston, MA 02114, USA
    Am J Psychiatry 163:1519-30; quiz 1665. 2006
    ..This study compared the effectiveness of lithium versus triiodothyronine (T(3)) augmentation as a third-step treatment for patients with major depressive disorder...
  85. ncbi request reprint Dropouts versus completers among chronically depressed outpatients
    Bruce A Arnow
    Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94305 5722, United States
    J Affect Disord 97:197-202. 2007
    ..Premature termination is common among patients treated for depression with either pharmacotherapy or psychotherapy. Yet little is known about factors associated with premature treatment termination among depressed patients...
  86. ncbi request reprint Psychotherapy and medication in the treatment of adult and geriatric depression: which monotherapy or combined treatment?
    Steven D Hollon
    Department of Psychology, Vanderbilt University, Nashville, TN 37203, USA
    J Clin Psychiatry 66:455-68. 2005
    ..The authors reviewed the literature with respect to the relative efficacy of medications and psychotherapy alone and in combination in the treatment of depression...
  87. ncbi request reprint A comparison of mirtazapine and nortriptyline following two consecutive failed medication treatments for depressed outpatients: a STAR*D report
    Maurizio Fava
    Depression Clinical and Research Program, Massachusetts General Hospital, Bulfinch 351, 55 Fruit St, Boston, MA 02114, USA
    Am J Psychiatry 163:1161-72. 2006
    ....
  88. pmc Intensive psychosocial intervention enhances functioning in patients with bipolar depression: results from a 9-month randomized controlled trial
    David J Miklowitz
    Department of Psychology, University of Colorado, Boulder, CO 80309 0345, USA
    Am J Psychiatry 164:1340-7. 2007
    ..In a randomized trial, the authors examined the impact of intensive psychosocial treatment plus pharmacotherapy on the functional outcomes of patients with bipolar disorder over the 9 months following a depressive episode...
  89. ncbi request reprint The Prevention of Recurrent Episodes of Depression with Venlafaxine for Two Years (PREVENT) study: outcomes from the acute and continuation phases
    Martin B Keller
    Brown University, Providence, Rhode Island 02906, USA
    Biol Psychiatry 62:1371-9. 2007
    ..We evaluated the comparative efficacy and safety of venlafaxine extended release (ER) and fluoxetine in the acute and continuation phases of treatment...
  90. ncbi request reprint Comprehensive analysis of remission (COMPARE) with venlafaxine versus SSRIs
    Charles B Nemeroff
    Department of Psychiatry and Behavioral Sciences, Emory University School of Medicine, Atlanta, Georgia 30322, USA
    Biol Psychiatry 63:424-34. 2008
    ..To compare venlafaxine and selective serotonin reuptake inhibitors (SSRIs; fluoxetine, sertraline, paroxetine, fluvoxamine, and citalopram) in the treatment of depression...
  91. ncbi request reprint Chronic depression: medication (nefazodone) or psychotherapy (CBASP) is effective when the other is not
    Alan F Schatzberg
    Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94305 5717, USA
    Arch Gen Psychiatry 62:513-20. 2005
    ..Although various strategies are available to manage nonresponders to an initial treatment for depression, no controlled trials address the utility of switching from an antidepressant medication to psychotherapy or vice versa...
  92. pmc Psychosocial treatments for bipolar depression: a 1-year randomized trial from the Systematic Treatment Enhancement Program
    David J Miklowitz
    Department of Psychology, University of Colorado, Boulder, CO 80309 0345, USA
    Arch Gen Psychiatry 64:419-26. 2007
    ..Psychosocial interventions have been shown to enhance pharmacotherapy outcomes in bipolar disorder...
  93. ncbi request reprint Effectiveness of adjunctive antidepressant treatment for bipolar depression
    Gary S Sachs
    Bipolar Clinic and Research Program, Massachusetts General Hospital, Harvard Medical School, Boston, MA 02114, USA
    N Engl J Med 356:1711-22. 2007
    ..Our study was designed to determine whether adjunctive antidepressant therapy reduces symptoms of bipolar depression without increasing the risk of mania...
  94. ncbi request reprint A multicenter, placebo-controlled study of modafinil augmentation in partial responders to selective serotonin reuptake inhibitors with persistent fatigue and sleepiness
    Maurizio Fava
    Depression Clinical and Research Program, Massachusetts General Hospital, Boston, MA 02114, USA
    J Clin Psychiatry 66:85-93. 2005
    ....
  95. ncbi request reprint Anxiety disorder comorbidity in bipolar disorder patients: data from the first 500 participants in the Systematic Treatment Enhancement Program for Bipolar Disorder (STEP-BD)
    Naomi M Simon
    Center for Anxiety and Traumatic Stress Related Disorders, Wang ACC 815, Massachusetts General Hospital, 15 Parkman St, Boston, MA 02114, USA
    Am J Psychiatry 161:2222-9. 2004
    ..The authors provide a detailed perspective on the correlates of comorbid anxiety in a large, well-characterized sample of bipolar disorder patients...
  96. doi request reprint The efficacy and safety of aripiprazole as adjunctive therapy in major depressive disorder: a second multicenter, randomized, double-blind, placebo-controlled study
    Ronald N Marcus
    Bristol Myers Squibb, Wallingford, CT 06492, USA
    J Clin Psychopharmacol 28:156-65. 2008
    ..1%] vs adjunctive aripiprazole [3.7%]). Aripiprazole is an effective and safe adjunctive therapy as demonstrated in this short-term study for patients who are nonresponsive to standard ADT...
  97. ncbi request reprint Pharmacotherapy for bipolar disorder and comorbid conditions: baseline data from STEP-BD
    Naomi M Simon
    Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA
    J Clin Psychopharmacol 24:512-20. 2004
    ..Our findings highlight the need for greater clinical guidance and treatment options for patients with bipolar disorder and comorbidity...
  98. ncbi request reprint Adjunctive antidepressant use and symptomatic recovery among bipolar depressed patients with concomitant manic symptoms: findings from the STEP-BD
    Joseph F Goldberg
    Affective Disorders Program, Silver Hill Hospital, New Canaan, Connecticut, USA
    Am J Psychiatry 164:1348-55. 2007
    ..However, few studies have examined the outcomes of patients with co-occurring manic and depressive symptoms who are treated with antidepressants plus mood stabilizing drugs...
  99. pmc Faster remission of chronic depression with combined psychotherapy and medication than with each therapy alone
    Rachel Manber
    Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, Stanford, CA 94305, USA
    J Consult Clin Psychol 76:459-67. 2008
    ..The authors conclude that combined antidepressant medications and psychotherapy result in faster full remission of chronic forms of major depressive disorder...
  100. ncbi request reprint The effectiveness of St. John's Wort in major depressive disorder: a naturalistic phase 2 follow-up in which nonresponders were provided alternate medication
    Alan J Gelenberg
    University of Arizona Health Sciences Center, Tucson, AZ 85724, USA
    J Clin Psychiatry 65:1114-9. 2004
    ..A continuation study of an extract of St. John's wort (Hypericum perforatum) for depression was performed in follow-up to an acute study that found no significant difference between St. John's wort extract and placebo...
  101. ncbi request reprint Therapeutic reactance as a predictor of outcome in the treatment of chronic depression
    Bruce A Arnow
    Department of Psychiatry and Behavioral Sciences, Stanford University School of Medicine, California 94305 5722, USA
    J Consult Clin Psychol 71:1025-35. 2003
    ..Results support the importance of Aptitude * Treatment interactions in psychotherapy outcome. The direction and significance of such interactions may vary with different forms of psychopathology...