Herve Tettelin

Summary

Affiliation: University of Maryland
Country: USA

Publications

  1. ncbi request reprint Comparative genomics: the bacterial pan-genome
    Herve Tettelin
    Institute for Genome Sciences, Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Curr Opin Microbiol 11:472-7. 2008
  2. pmc Phenotypic, genomic, and transcriptional characterization of Streptococcus pneumoniae interacting with human pharyngeal cells
    Sheila Z Kimaro Mlacha
    Kenya Medical Research Institute, Wellcome Trust Research Programme, Kilifi, Kenya
    BMC Genomics 14:383. 2013
  3. pmc Transcriptional adaptation of pneumococci and human pharyngeal cells in the presence of a virus infection
    Sheila Z Kimaro Mlacha
    Kenya Medical Research Institute, Wellcome Trust Research Programme, Kilifi, Kenya
    BMC Genomics 14:378. 2013
  4. pmc Genomic insights into the emerging human pathogen Mycobacterium massiliense
    Herve Tettelin
    Institute for Genome Sciences, Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland, USA
    J Bacteriol 194:5450. 2012
  5. pmc Structure and dynamics of the pan-genome of Streptococcus pneumoniae and closely related species
    Claudio Donati
    Novartis Vaccines and Diagnostics, Via Fiorentina 1, 53100 Siena, Italy
    Genome Biol 11:R107. 2010
  6. pmc Pyrosequencing-based comparative genome analysis of the nosocomial pathogen Enterococcus faecium and identification of a large transferable pathogenicity island
    Willem van Schaik
    Department of Medical Microbiology, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    BMC Genomics 11:239. 2010
  7. pmc Acidithiobacillus ferrooxidans metabolism: from genome sequence to industrial applications
    Jorge Valdes
    Center for Bioinformatics and Genome Biology, FundaciĆ³n Ciencia para la Vida, Facultad de Ciencias de la Salud, Universidad Andres Bello, Santiago, Chile
    BMC Genomics 9:597. 2008
  8. pmc Improving pan-genome annotation using whole genome multiple alignment
    Samuel V Angiuoli
    Center for Bioinformatics and Computational Biology, University of Maryland, College Park, MD 20742, USA
    BMC Bioinformatics 12:272. 2011
  9. pmc Comparative genomics of emerging human ehrlichiosis agents
    Julie C Dunning Hotopp
    The Institute for Genomic Research, Rockville, Maryland, USA
    PLoS Genet 2:e21. 2006
  10. pmc Whole-genome association study on tissue tropism phenotypes in group A Streptococcus
    Debra E Bessen
    New York Medical College, Department of Microbiology and Immunology, Valhalla, NY 10595, USA
    J Bacteriol 193:6651-63. 2011

Collaborators

Detail Information

Publications17

  1. ncbi request reprint Comparative genomics: the bacterial pan-genome
    Herve Tettelin
    Institute for Genome Sciences, Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD 21201, USA
    Curr Opin Microbiol 11:472-7. 2008
    ..Different models exist for the analysis and their accuracy and applicability depend on the case at hand. Here we discuss current models and suggest a new model of broad applicability, including examples of its implementation...
  2. pmc Phenotypic, genomic, and transcriptional characterization of Streptococcus pneumoniae interacting with human pharyngeal cells
    Sheila Z Kimaro Mlacha
    Kenya Medical Research Institute, Wellcome Trust Research Programme, Kilifi, Kenya
    BMC Genomics 14:383. 2013
    ..Understanding the molecular interactions between the bacterium and the host will contribute to the control and prevention of pneumococcal disease...
  3. pmc Transcriptional adaptation of pneumococci and human pharyngeal cells in the presence of a virus infection
    Sheila Z Kimaro Mlacha
    Kenya Medical Research Institute, Wellcome Trust Research Programme, Kilifi, Kenya
    BMC Genomics 14:378. 2013
    ..The objective of this study is to describe a comprehensive picture of the cellular interaction between the adhering bacteria and host cells in the presence or absence of a viral co-infection...
  4. pmc Genomic insights into the emerging human pathogen Mycobacterium massiliense
    Herve Tettelin
    Institute for Genome Sciences, Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland, USA
    J Bacteriol 194:5450. 2012
    ..Mycobacterium massiliense (Mycobacterium abscessus group) is an emerging pathogen causing pulmonary disease and skin and soft tissue infections. We report the genome sequence of the type strain CCUG 48898...
  5. pmc Structure and dynamics of the pan-genome of Streptococcus pneumoniae and closely related species
    Claudio Donati
    Novartis Vaccines and Diagnostics, Via Fiorentina 1, 53100 Siena, Italy
    Genome Biol 11:R107. 2010
    ..Streptococcus pneumoniae is one of the most important causes of microbial diseases in humans. The genomes of 44 diverse strains of S. pneumoniae were analyzed and compared with strains of non-pathogenic streptococci of the Mitis group...
  6. pmc Pyrosequencing-based comparative genome analysis of the nosocomial pathogen Enterococcus faecium and identification of a large transferable pathogenicity island
    Willem van Schaik
    Department of Medical Microbiology, University Medical Center Utrecht, Heidelberglaan 100, 3584 CX Utrecht, The Netherlands
    BMC Genomics 11:239. 2010
    ..The Gram-positive bacterium Enterococcus faecium is an important cause of nosocomial infections in immunocompromized patients...
  7. pmc Acidithiobacillus ferrooxidans metabolism: from genome sequence to industrial applications
    Jorge Valdes
    Center for Bioinformatics and Genome Biology, FundaciĆ³n Ciencia para la Vida, Facultad de Ciencias de la Salud, Universidad Andres Bello, Santiago, Chile
    BMC Genomics 9:597. 2008
    ..Also, confusion has been caused by prior metabolic models constructed based upon the examination of multiple, and sometimes distantly related, strains of the microorganism...
  8. pmc Improving pan-genome annotation using whole genome multiple alignment
    Samuel V Angiuoli
    Center for Bioinformatics and Computational Biology, University of Maryland, College Park, MD 20742, USA
    BMC Bioinformatics 12:272. 2011
    ..Genome annotations can contain inconsistencies and errors that hinder comparative analysis even within a single species. Tools are needed to compare and improve annotation quality across sets of closely related genomes...
  9. pmc Comparative genomics of emerging human ehrlichiosis agents
    Julie C Dunning Hotopp
    The Institute for Genomic Research, Rockville, Maryland, USA
    PLoS Genet 2:e21. 2006
    ..These discoveries provide significant insights into the biology of these obligate intracellular pathogens...
  10. pmc Whole-genome association study on tissue tropism phenotypes in group A Streptococcus
    Debra E Bessen
    New York Medical College, Department of Microbiology and Immunology, Valhalla, NY 10595, USA
    J Bacteriol 193:6651-63. 2011
    ..This study employs a novel synthesis of tools to help delineate the major genetic changes associated with key adaptive shifts in an extensively recombined bacterial species...
  11. pmc Using Sybil for interactive comparative genomics of microbes on the web
    David R Riley
    Institute for Genome Sciences, University of Maryland School of Medicine, Baltimore, MD, USA
    Bioinformatics 28:160-6. 2012
    ..In addition to scalability, comparative genomics tools must also provide user-friendly interfaces such that the research scientist can explore complex data with minimal technical expertise...
  12. ncbi request reprint Widespread lateral gene transfer from intracellular bacteria to multicellular eukaryotes
    Julie C Dunning Hotopp
    Institute for Genomic Research, J Craig Venter Institute, 9712 Medical Center Drive, Rockville, MD 20850, USA
    Science 317:1753-6. 2007
    ..Therefore, heritable lateral gene transfer occurs into eukaryotic hosts from their prokaryote symbionts, potentially providing a mechanism for acquisition of new genes and functions...
  13. pmc Phylogenomics of the reproductive parasite Wolbachia pipientis wMel: a streamlined genome overrun by mobile genetic elements
    Martin Wu
    The Institute for Genomic Research, Rockville, Maryland, USA
    PLoS Biol 2:E69. 2004
    ..With the availability of the complete genomes of both species and excellent genetic tools for the host, the wMel-D. melanogaster symbiosis is now an ideal system for studying the biology and evolution of Wolbachia infections...
  14. doi request reprint Bacterial genome sequencing
    Herve Tettelin
    Institute for Genome Sciences, Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD, USA
    Methods Mol Biol 551:231-47. 2009
    ..We review a number of sequencing technologies and provide examples of applications. We also discuss the impact genomics and new DNA sequencing approaches have had on various fields of biological research...
  15. pmc Genome-wide identification of genes required for fitness of group A Streptococcus in human blood
    Yoann Le Breton
    Department of Cell Biology and Molecular Genetics and Maryland Pathogen Research Institute, University of Maryland, College Park, Maryland, USA
    Infect Immun 81:862-75. 2013
    ..Overall, this work represents the first use of TraSH in GAS to identify potential virulence genes...
  16. pmc Genomic insights into methanotrophy: the complete genome sequence of Methylococcus capsulatus (Bath)
    Naomi Ward
    The Institute for Genomic Research, Rockville, Maryland, USA
    PLoS Biol 2:e303. 2004
    ..We have gained evidence for greater metabolic flexibility than was previously known, and for genetic components that may have biotechnological potential...
  17. pmc New Rapid Scheme for Distinguishing the Subspecies of the Mycobacterium abscessus Group and Identifying Mycobacterium massiliense Isolates with Inducible Clarithromycin Resistance
    Shamira J Shallom
    Microbiology Service, Department of Laboratory Medicine, Clinical Center, National Institutes of Health, Bethesda, Maryland, USA
    J Clin Microbiol 51:2943-9. 2013
    ..bolletii and the assessment of inducible clarithromycin resistance. This method can be easily integrated into a routine workflow to provide subspecies-level identification within 24 h after isolation of the M. abscessus group. ..