Research Topics
Species | Jonathan P TerdimanSummaryAffiliation: University of California Country: USA Publications
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Detail Information
Publications
Prevention of postoperative recurrence in Crohn's diseaseJonathan P Terdiman
University of California, San Francisco, San Francisco, California 94115, USA
Clin Gastroenterol Hepatol 6:616-20. 2008- Update on upper gastrointestinal bleeding. Basing treatment decisions on patients' risk levelJ P Terdiman
University of California, San Francisco School of Medicine, USA
Postgrad Med 103:43-7, 51-2, 58-9 passim. 1998..Early assessment helps identify low-risk patients in whom discharge on the day of presentation is appropriate... - Colorectal cancer at a young ageJonathan P Terdiman
Division of Gastroenterology, University of California, San Francisco, CA 94115, USA
Gastroenterology 128:1067-76. 2005 - High resolution analysis of chromosome 18 alterations in ulcerative colitis-related colorectal cancerJonathan P Terdiman
Cancer Center, University of California San Francisco, San Francisco, CA, USA
Cancer Genet Cytogenet 136:129-37. 2002..SMAD2 was retained in four tumors having loss of SMAD4 and DCC. Loss of SMAD4 alone was seen in one tumor. The present data indicate that the loss of SMAD4 and DCC occurs in the majority of colitis-related cancers... - Hereditary nonpolyposis colorectal cancer in young colorectal cancer patients: high-risk clinic versus population-based registryJonathan P Terdiman
Department of Medicine, University of California, San Francisco 94143, USA
Gastroenterology 122:940-7. 2002..We sought to compare rates of genetically defined HNPCC among individuals with early onset CRC drawn from a high-risk clinic and a population-based cancer registry... - Colonoscopic management of lower gastrointestinal hemorrhageJ P Terdiman
Department of Medicine, University of California, San Francisco, Box 1623, San Francisco, CA 94143, USA
Curr Gastroenterol Rep 3:425-32. 2001..It also appears that therapeutic colonoscopy can arrest or prevent bleeding in certain high-risk patients, offering the opportunity to change the natural history of the bleed... - Efficient detection of hereditary nonpolyposis colorectal cancer gene carriers by screening for tumor microsatellite instability before germline genetic testingJ P Terdiman
Department of Medicine, University of California, San Francisco, San Francisco, California, USA
Gastroenterology 120:21-30. 2001..We evaluated whether microsatellite instability (MSI) analysis or MSH2 and MLH1 protein immunostaining of tumors will screen individuals efficiently for germline MSH2 and MLH1 testing... - Low rate of microsatellite instability in young patients with adenomas: reassessing the Bethesda guidelinesFernando S Velayos
Division of Gastroenterology and Colorectal Cancer Prevention Program, University of California, San Francisco, CA, USA
Am J Gastroenterol 100:1143-9. 2005..New strategies that improve on the current clinical and molecular screening methods should be developed so that at-risk individuals can be identified and referred for germline testing before developing their first cancer... - Regional hypermethylation and global hypomethylation are associated with altered chromatin conformation and histone acetylation in colorectal cancerGuoren Deng
Gastrointestinal Research Laboratory, Veteran Affairs Medical Center and Department of Medicine, University of California San Francisco, 94121, USA
Int J Cancer 118:2999-3005. 2006.... - A comparison of the phenotype and genotype in adenomatous polyposis patients with and without a family historyBrindusa Truta
Department of Medicine, Division of Gastroenterology and the Comprehensive Cancer Center, University of California San Francisco, 2330 Post Street, San Francisco, CA 94115 1623, USA
Fam Cancer 4:127-33. 2005..We studied the phenotype and genotype of adenomatous polyposis in patients without a family history... - The mechanism of microsatellite instability is different in synchronous and metachronous colorectal cancerFernando S Velayos
Division of Gastroenterology and Colorectal Cancer Prevention Center, Department of Medicine, University of California San Francisco, California, USA
J Gastrointest Surg 9:329-35. 2005..In contrast, more MSI-H metachronous CRCs were associated with patient and tumor characteristics suggestive of underlying hereditary nonpolyposis CRC... - BRAF mutation is frequently present in sporadic colorectal cancer with methylated hMLH1, but not in hereditary nonpolyposis colorectal cancerGuoren Deng
Department of Medicine, Veteran Affairs Medical Center and Cancer Center, University of California San Francisco, California, USA
Clin Cancer Res 10:191-5. 2004..In this study, we sought to compare the frequencies of BRAF mutations in sporadic colorectal cancer with MSI with those in hereditary nonpolyposis colorectal cancer (HNPCC)... - Comparison of selection strategies for genetic testing of patients with hereditary nonpolyposis colorectal carcinoma: effectiveness and cost-effectivenessCarolina M Reyes
Department of Clinical Pharmacy, University of California, San Francisco 94143, USA
Cancer 95:1848-56. 2002..However, testing all CRC patients for tumor MSI-H, although effective, may be prohibitively expensive. A mixed strategy is the more cost-effective approach... 
Chemoprevention of colonic polyps with balsalazide: an exploratory, double-blind, placebo-controlled studyJonathan P Terdiman
Division of Gastroenterology, Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA
Dig Dis Sci 54:2488-96. 2009..Preclinical data suggest that 5-aminosalicylates also may have a chemopreventive effect...
Tumor histology helps to identify Lynch syndrome among colorectal cancer patientsBrindusa Truta
Department of Medicine, Gastroenterology Division, University California San Francisco, 2330 Post St, Suite 610, San Francisco, CA 94115, USA
Fam Cancer 7:267-74. 2008..To determine the value of histology in identifying Lynch syndrome among those patients with early onset of colorectal cancer (CRC)...- Colorectal cancer screening: clinical applicationsJudith M E Walsh
Division of General Internal Medicine, Department of Medicine, Women s Health Clinical Research Center, University of California San Francisco, Campus Box 1793, 1635 Divisadero Suite 600, San Francisco, CA 94115, USA
JAMA 289:1297-302. 2003..Many potential barriers to colorectal cancer screening exist for the patient and the physician. Strategies to increase compliance for colorectal cancer screening are proposed... - Hospitalized ulcerative colitis patients have an elevated risk of thromboembolic eventsJennifer Y Wang
Department of Surgery, University of California San Francisco, San Francisco, CA 94143, USA
World J Gastroenterol 15:927-35. 2009..To compare thromboembolism rates between patients with ulcerative colitis undergoing a colorectal operation and other patients undergoing colorectal operations... - Controversies in the treatment of Crohn's disease: the case for an accelerated step-up treatment approachAmandeep K Shergill
Veterans Affairs Medical Center, Division of Gastroenterology, University of California, San Francisco 94143, United States
World J Gastroenterol 14:2670-7. 2008.... - Chromosomal instability in microsatellite-unstable and stable colon cancerKarolin Trautmann
Comprehensive Cancer Center, Department of Medicine, University of California San Francisco, San Francisco, California 94143-0808, USA
Clin Cancer Res 12:6379-85. 2006..CONCLUSION: MSI and CIN are not mutually exclusive forms of genomic instability in sporadic colon cancer, with MSI tumors also showing varying degrees of CIN... - Durability of infliximab dose intensification in Crohn's diseaseKirk K Lin
Division of Gastroenterology, Department of Internal Medicine, University of California at San Francisco, San Francisco, CA, USA
Dig Dis Sci 57:1013-9. 2012..Dose intensification is a common approach to treat Crohn's disease (CD) patients who lose response to infliximab maintenance therapy. Few studies have reported upon its long-term efficacy or predictors of response... - Colorectal cancer screening: scientific reviewJudith M E Walsh
Division of General Internal Medicine, Department of Medicine, Women s Health Clinical Research Center, University of California San Francisco, Campus Box 1793, 1635 Divisadero Suite 600, San Francisco, CA 94115, USA
JAMA 289:1288-96. 2003..Clinicians are challenged to ensure that eligible patients undergo colorectal cancer screening and to guide patients in choosing what tests to receive... - Endoscopic management of familial colonic neoplasiaYuki Young
Division of Gastroenterology, Department of Medicine, University of California, San Francisco, 94115, USA
Gastrointest Endosc Clin N Am 15:549-80, ix-x. 2005..Genetic testing is commercially available for most of the hereditary colorectal cancer syndromes and can greatly facilitate the management of patients if properly undertaken... - Fractional genomic alteration detected by array-based comparative genomic hybridization independently predicts survival after hepatic resection for metastatic colorectal cancerKshama R Mehta
Comprehensive Cancer Center, Department of Surgery, University of California-San Francisco, 2340 Sutter Street, San Francisco, CA 94143, USA
Clin Cancer Res 11:1791-7. 2005..CONCLUSIONS: Both FGA and CRS are independent predictors of survival in patients with resected hepatic colorectal cancer metastases. The greater the FGA, the more likely the patient is to survive... - 5-Aminosalicylic acid therapy and the risk of colorectal cancer among patients with inflammatory bowel diseaseJonathan P Terdiman
University of California, San Francisco, San Francisco, California 94143 1623, USA
Inflamm Bowel Dis 13:367-71. 2007..The objective of this observational study was to determine if an association between 5-ASA therapy and CRC risk exists in IBD patients... - Oncology training for the gastroenterologist: a test-case for subspecialization in gastroenterology?Jonathan P Terdiman
University of California, San Francisco, San Francisco, California 94143, USA
Gastroenterology 135:1028-31. 2008 - Intentional infliximab use during pregnancy for induction or maintenance of remission in Crohn's diseaseU Mahadevan
Division of Gastroenterology, Department of Medicine, University of California San Francisco, CA 94115, USA
Aliment Pharmacol Ther 21:733-8. 2005..To study the effects of infliximab on pregnancy and foetal outcome... - Association of large serrated polyps with synchronous advanced colorectal neoplasiaDan Li
Department of Medicine, University of California, San Francisco, 94115, USA
Am J Gastroenterol 104:695-702. 2009..Accumulating evidence suggests that they may have different malignancy potentials. This study sought to determine the association between the presence of large serrated colorectal polyps and synchronous advanced colorectal neoplasia... - Ulcerative colitis patients with dysplastic polyps should be advised to undergo colectomyJonathan P Terdiman
Center for Colitis and Crohn's Disease, University of California, San Francisco, San Francisco, CA 94115, USA
Inflamm Bowel Dis 12:916-8. 2006 - Promoting use of colorectal cancer screening tests. Can we change physician behavior?Judith M E Walsh
Division of General Internal Medicine, Department of Medicine, University of California, San Francisco, California, USA
J Gen Intern Med 20:1097-101. 2005..Colorectal cancer (CRC) screening is underutilized despite evidence that screening reduces mortality... - Effect of 5-aminosalicylate use on colorectal cancer and dysplasia risk: a systematic review and metaanalysis of observational studiesFernando S Velayos
Division of Gastroenterology and UCSF Center for Colitis and Crohn's Disease, University of California, San Francisco, California 94143, USA
Am J Gastroenterol 100:1345-53. 2005..Additional studies analyzing the effect of 5-ASA on risk of dysplasia are needed... - Colorectal cancer risk perception on the basis of genetic test results in individuals at risk for Lynch syndromeShilpa Grover
Division of Gastroenterology, Department of Medicine, Brigham and Women s Hospital, Boston, MA, USA
J Clin Oncol 27:3981-6. 2009..This study examines colorectal cancer (CRC) risk perception in individuals tested for MMR mutations and identifies the factors associated with an appropriate interpretation of their cancer risk... - Genotype and phenotype of patients with both familial adenomatous polyposis and thyroid carcinomaBrindusa Truta
University California San Francisco, Department of Medicine, Comprehensive Cancer Center, San Francisco, California, USA
Fam Cancer 2:95-9. 2003..Additionally, thyroid cancer in our patients occurred in the setting of classic FAP phenotype. Germline mutations were located predominantly outside the APC mutation cluster region... - Gross versus microscopic pancolitis and the occurrence of neoplasia in ulcerative colitisChristian Mathy
Division of Gastroenterology, Department of Medicine, University of California, San Francisco 94115, USA
Inflamm Bowel Dis 9:351-5. 2003..To devise rational cancer surveillance guidelines, further studies are needed to determine the risk of colitis-related neoplasia in patients with microscopic pancolitis but limited gross disease... - Screening prevalence and incidence of colorectal cancer among American Indian/Alaskan natives in the Indian Health ServiceLukejohn W Day
Division of Gastroenterology, San Francisco General Hospital 3D, 1001 Potrero Avenue, San Francisco, CA 94110, USA
Dig Dis Sci 56:2104-13. 2011..Studies on colorectal cancer (CRC) screening and incidence among American Indian/Alaska Natives (AI/AN) are few... - Early predictors of severe lower gastrointestinal bleeding and adverse outcomes: a prospective studyFernando S Velayos
Division of Gastroenterology, University of California San Francisco, 94143, USA
Clin Gastroenterol Hepatol 2:485-90. 2004..Severe lower gastrointestinal bleeding is a significant risk factor for global adverse outcomes... - Hereditary polyposis syndromes and hereditary non-polyposis colorectal cancerBrian A Allen
University of California, San Francisco, 1600 Divisadero Street Box 1623, San Francisco, CA 94143, USA
Best Pract Res Clin Gastroenterol 17:237-58. 2003.... - Evidence-based analysis: postoperative gastric bleeding: etiology and preventionJade S Hiramoto
Department of Surgery, University of California, 533 Parnassus Ave Room U-372, San Francisco, CA 94143-7088, USA
Surg Oncol 12:9-19. 2003..Intravenous proton pump inhibitors may be the drugs of choice for stress ulcer prophylaxis (SUP) in high-risk patients... - Infliximab and semen quality in men with inflammatory bowel diseaseUma Mahadevan
Division of Gastroenterology, Department of Medicine, University of California, San Francisco, California 94115, USA
Inflamm Bowel Dis 11:395-9. 2005..There is no available data on the effects of infliximab on semen quality. The aim of this study was to determine whether changes in semen quality occurred in men receiving infliximab... - Gender as a risk factor for advanced neoplasia and colorectal cancer: a systematic review and meta-analysisStephen P Nguyen
Division of Gastroenterology, Department of Medicine, University of California, San Francisco, San Francisco, California 94143, USA
Clin Gastroenterol Hepatol 7:676-81.e1-3. 2009..Studies have reported higher rates of advanced colorectal neoplasia in men than in women. We performed a meta-analysis to provide a quantitative pooled risk estimate of the association between gender and advanced colorectal neoplasia... - Colorectal Cancer Screening Clinical Practice GuidelinesBernard Levin
J Natl Compr Canc Netw 4:384-420. 2006 - The APC/beta-catenin pathway in ulcerative colitis-related colorectal carcinomas: a mutational analysisDaniela E Aust
Pathologisches Institut der Ludwig Maximilians Universität, Munchen, Germany
Cancer 94:1421-7. 2002..To elucidate the role of the APC-/beta-catenin pathway in UC-related carcinogenesis, the authors identified APC and beta-catenin mutations in a set of UC-related and sporadic colorectal carcinomas... - It is time to get serious about diagnosing Lynch syndrome (hereditary nonpolyposis colorectal cancer with defective DNA mismatch repair) in the general populationJonathan P Terdiman
Gastroenterology 129:741-4. 2005 - Lower cancer incidence in Amsterdam-I criteria families without mismatch repair deficiency: familial colorectal cancer type XNoralane M Lindor
Department of Medical Genetics, Mayo Clinic, Rochester, Minn, USA
JAMA 293:1979-85. 2005..Cancer incidence in AC-I families with MMR gene mutations is reported to be very high, but cancer incidence for individuals in AC-I families with no evidence of an MMR defect is unknown... - Revised Bethesda Guidelines for hereditary nonpolyposis colorectal cancer (Lynch syndrome) and microsatellite instabilityAsad Umar
Division of Cancer Prevention, National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Bethesda, MD 20892, USA
J Natl Cancer Inst 96:261-8. 2004.... - High-resolution analysis of DNA copy number alterations in colorectal cancer by array-based comparative genomic hybridizationKentaro Nakao
Second Department of Surgery, Showa University School of Medicine, Tokyo, Japan
Carcinogenesis 25:1345-57. 2004..Array-based CGH was also able to identify DNA copy number changes in MSI-H tumors... - Aspirin curbs colon polyps. But for many, bleeding risks may offset benefitsJonathan P Terdiman
Health News 9:1-2. 2003