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Genomes and GenesSpecies | Masanori TerajimaSummaryAffiliation: University of Massachusetts Medical School Country: USA Publications
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Publications
The N-terminus of vaccinia virus host range protein C7L is essential for functionMasanori Terajima
Division of Infectious Diseases and Immunology, Department of Medicine, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA
Virus Genes 46:20-7. 2013....
Role of Indoleamine 2,3-Dioxygenase in Antiviral Activity of Interferon-gamma Against Vaccinia VirusMasanori Terajima
Center for Infectious Disease and Vaccine Research, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
Viral Immunol 18:722-9. 2005..IDO may account for the NOS2-independent antiviral mechanism induced by IFN-gamma. IFN-gamma may use different antiviral mechanisms in different cell types...- Identification of vaccinia CD8+ T-cell epitopes conserved among vaccinia and variola viruses restricted by common MHC class I molecules, HLA-A2 or HLA-B7Masanori Terajima
Center for Infectious Disease and Vaccine Research, University of Massachusetts Medical School, Worcester, MA, 01655, USA
Hum Immunol 67:512-20. 2006..Combined with previous reports by us and others, these results show that there are some vaccinia viral proteins containing multiple epitopes restricted by different MHC molecules of humans and mice... - Vaccinia virus-specific CD8(+) T-cell responses target a group of epitopes without a strong immunodominance hierarchy in humansMasanori Terajima
Center for Infectious Disease and Vaccine Research, University of Massachusetts Medical School, Worcester, MA 01655, USA
Hum Immunol 69:815-25. 2008.... - Complement-dependent lysis of influenza a virus-infected cells by broadly cross-reactive human monoclonal antibodiesMasanori Terajima
Center for Infectious Disease and Vaccine Research, Division of Infectious Diseases and Immunology, Department of Medicine, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA
J Virol 85:13463-7. 2011.... - Influenza A virus matrix protein 1-specific human CD8+ T-cell response induced in trivalent inactivated vaccine recipientsMasanori Terajima
Center for Infectious Disease and Vaccine Research, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA
J Virol 82:9283-7. 2008..These data show that TIV, which is formulated to contain surface glycoproteins to induce serotype-specific antibody responses, also contains M1, capable of inducing subtype cross-reactive CD8+ T-cell responses in some vaccinees... - T cells and pathogenesis of hantavirus cardiopulmonary syndrome and hemorrhagic fever with renal syndromeMasanori Terajima
Center for Infectious Disease and Vaccine Research, Division of Infectious Diseases and Immunology, Department of Medicine, University of Massachusetts Medical School, Worcester, MA 01655, USA
Viruses 3:1059-73. 2011.... - Discordance between antibody and T cell responses in recipients of trivalent inactivated influenza vaccineMary Dawn T Co
Center for Infectious Disease and Vaccine Research, University of Massachusetts Medical School, Worcester, MA 01655, United States
Vaccine 26:1990-8. 2008..These results show specific increases in a CD8 T cell subset and discordant T and B responses induced by the trivalent inactivated influenza vaccine... - In vitro evidence that commercial influenza vaccines are not similar in their ability to activate human T cell responsesMary Dawn T Co
Center for Infectious Disease and Vaccine Research, University of Massachusetts Medical School, Worcester, MA 01655, USA
Vaccine 27:319-27. 2009..These data suggest that TIV vaccines are not similar in their ability to activate human T cell responses... - Genome-wide screening of human T-cell epitopes in influenza A virus reveals a broad spectrum of CD4(+) T-cell responses to internal proteins, hemagglutinins, and neuraminidasesJenny Aurielle B Babon
Center for Infectious Disease and Vaccine Research, University of Massachusetts Medical School, Worcester, MA 01655, USA
Hum Immunol 70:711-21. 2009..Our genome-wide screening is useful in identifying T-cell epitopes and is complementary to the approach based on the predicted binding peptides to well-studied HLA-A, -B, and -DR alleles... - Recombinant adenovirus vector vaccine induces stronger cytotoxic T-cell responses than recombinant vaccinia virus vector, plasmid DNA, or a combination of theseKen Maeda
Center for Infectious Disease and Vaccine Research, University of Massachusetts Medical School, Worcester, Massachusetts 01655, USA
Viral Immunol 18:657-67. 2005.... - Identification of murine poxvirus-specific CD8+ CTL epitopes with distinct functional profilesAnuja Mathew
Center for Infectious Disease and Vaccine Research, University of Massachusetts Medical School, Worcester, MA 01655, USA
J Immunol 174:2212-9. 2005..Identification of T cell epitopes on VV will enable further studies to increase our understanding of the role of CD8+ T cells in VV infection and assist in the design of new protective strategies... - Identification and analysis for cross-reactivity among hantaviruses of H-2b-restricted cytotoxic T-lymphocyte epitopes in Sin Nombre virus nucleocapsid proteinKen Maeda
Center for Infectious Disease and Vaccine Research, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA
J Gen Virol 85:1909-19. 2004..These results will enable the analysis of the roles of CTL in immunopathology of HPS in experimental mouse models of HPS... - Quantitation of CD8+ T cell responses to newly identified HLA-A*0201-restricted T cell epitopes conserved among vaccinia and variola (smallpox) virusesMasanori Terajima
Center for Infectious Disease and Vaccine Research, University of Massachusetts Medical School, 55 Lake Ave. North, Worcester, MA 01655, USA
J Exp Med 197:927-32. 2003..This information will be useful for studies of human T cell memory and for the design and analyses of the immunogenicity of experimental vaccinia vaccines... - Robust intrapulmonary CD8 T cell responses and protection with an attenuated N1L deleted vaccinia virusAnuja Mathew
Center for Infectious Disease and Vaccine Research, University of Massachusetts Medical School, Worcester, Massachusetts, USA
PLoS ONE 3:e3323. 2008..Vaccinia viruses have been used as a model for viral disease and as a protective live vaccine... - Long-lived memory T lymphocyte responses after hantavirus infectionHeather L Van Epps
Center for Infectious Disease and Vaccine Research, University of Massachusetts Medical School, Worcester, MA 01655, USA
J Exp Med 196:579-88. 2002..The frequencies of PUUV-specific CTL were comparable to or exceeded those found in other viral systems including influenza, EBV and HIV, in which CTL responses may be boosted by periodic reinfection or virus persistence... - Human cytotoxic CD4+ T cells recognize HLA-DR1-restricted epitopes on vaccinia virus proteins A24R and D1R conserved among poxvirusesShibani Mitra Kaushik
Center for Infectious Disease and Vaccine Research, University of Massachusetts Medical School, Worcester, MA 01655, USA
J Immunol 179:1303-12. 2007.... - Pathogeneses of respiratory infections with virulent and attenuated vaccinia virusesDaisuke Hayasaka
Center for Infectious Disease and Vaccine Research, University of Massachusetts Medical School, Worcester, MA 01655, USA
Virol J 4:22. 2007..In this study, we analyzed virus replication and host immune responses after intranasal infection with lethal and non-lethal doses of VV using the WR strain and the less virulent Wyeth strain... - Role of specific CD8+ T cells in the severity of a fulminant zoonotic viral hemorrhagic fever, hantavirus pulmonary syndromeElizabeth D Kilpatrick
Center for Infectious Disease and Vaccine Research, and Department of Pediatrics and Program in Molecular Medicine, University of Massachusetts Medical School, Worcester, MA 01655, USA
J Immunol 172:3297-304. 2004..Intense CD8(+) T cell responses to SNV may be induced by the encounter of the unnatural human host to this zoonotic virus without coevolution. This may also be the immunopathologic basis of other life-threatening human virus infections... - Increased permeability of human endothelial cell line EA.hy926 induced by hantavirus-specific cytotoxic T lymphocytesDaisuke Hayasaka
Center for Infectious Disease and Vaccine Research, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA
Virus Res 123:120-7. 2007..These results suggest that cytotoxic T lymphocyte activity contribute to capillary leakage observed in patients with hantavirus pulmonary syndrome or hemorrhagic fever with renal syndrome... - Development of antigen-specific memory CD8+ T cells following live-attenuated chimeric West Nile virus vaccinationHeidi L Smith
Center for Infectious Disease and Vaccine Research, University of Massachusetts Medical School, Worcester, MA 01655, USA
J Infect Dis 203:513-22. 2011..WNV E-specific CD8(+) T cell responses were detected for up to 1 year after vaccination. The evolution of this WNV-specific T cell response is similar to that observed in established, highly immunogenic vaccines... - Human cytotoxic T lymphocyte responses to live attenuated 17D yellow fever vaccine: identification of HLA-B35-restricted CTL epitopes on nonstructural proteins NS1, NS2b, NS3, and the structural protein EMary Dawn T Co
Center for Infectious Disease and Vaccine Research, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, Massachusetts 01655, USA
Virology 293:151-63. 2002..These results indicate that the live 17D YFV vaccine induced CD8(+) T cell responses directed against at least four different HLA-B35-restricted YFV epitopes... - Generation of recombinant vaccinia viruses expressing Puumala virus proteins and use in isolating cytotoxic T cells specific for Puumala virusMasanori Terajima
Center for Infectious Disease and Vaccine Research, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA
Virus Res 84:67-77. 2002..An HLA-A24-restricted CTL line recognizing the G2 protein was isolated and its 9-mer epitope was determined... - Immune responses to Puumala virus infection and the pathogenesis of nephropathia epidemicaMasanori Terajima
Center for Infectious Disease and Vaccine Research, S5-326 University of Massachusetts Medical School, Worcester, 01655, USA
Microbes Infect 6:238-45. 2004..The virus itself is not cytopathic, and the immune responses to the virus may be involved in teh pathogenesis of the disease... - A human CD4+ T cell epitope in the influenza hemagglutinin is cross-reactive to influenza A virus subtypes and to influenza B virusJenny Aurielle B Babon
Division of Infectious Diseases and Immunology, Department of Medicine, University of Massachusetts Medical School, Worcester, Massachusetts, USA
J Virol 86:9233-43. 2012.... - Quantitation of antibody-bound and unbound Sin Nombre virus in the plasma of patient with hantavirus pulmonary syndromeMasanori Terajima
Center for Infectious Disease and Vaccine Research, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA
J Virol Methods 110:159-62. 2003..05) and the neutralizing antibody titers of plasma (P<0.05). This quantitative method may be useful to examine diseases where immune complex formation or antibody-dependent enhancement may be involved in pathogenesis... - Comparison of complement dependent lytic, hemagglutination inhibition and microneutralization antibody responses in influenza vaccinated individualsMary Dawn T Co
Department of Medicine, University of Massachusetts Medical School, Worcester, MA, USA
Hum Vaccin Immunother 8:1218-22. 2012..The biological significance of these CDL antibodies merits further investigation in clinical studies... - Vaccinia virus K1L protein mediates host-range function in RK-13 cells via ankyrin repeat and may interact with a cellular GTPase-activating proteinRitu R Bradley
Center for Infectious Disease and Vaccine Research, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655, USA
Virus Res 114:104-12. 2005..Our result suggests the importance of ankyrin repeat for host-range function of K1L in RK-13 cells and identifies ACAP2 as a cellular protein, which may be interacting with K1L... - Using HLA-transgenic mice to identify immunodominant human CD8+ T cell epitopes--does (genome) size matter?Masanori Terajima
Immunol Lett 105:97-8. 2006 - Immunopathogenesis of hantavirus pulmonary syndrome and hemorrhagic fever with renal syndrome: Do CD8+ T cells trigger capillary leakage in viral hemorrhagic fevers?Masanori Terajima
Immunol Lett 113:117-20. 2007..CD8+ T cells may be a potential target for therapy of some viral hemorrhagic fevers...