Joel Tepper

Summary

Affiliation: University of North Carolina
Country: USA

Publications

  1. ncbi Phase III trial of trimodality therapy with cisplatin, fluorouracil, radiotherapy, and surgery compared with surgery alone for esophageal cancer: CALGB 9781
    Joel Tepper
    Department of Radiation Oncology, University of North Carolina School of Medicine, Chapel Hill, NC 27599 7512, USA
    J Clin Oncol 26:1086-92. 2008
  2. ncbi Analysis of surgical salvage after failure of primary therapy in rectal cancer: results from Intergroup Study 0114
    J E Tepper
    Department of Radiation Oncology, Campus Box No 7512, University of North Carolina, Chapel Hill, NC 27599 7512, USA
    J Clin Oncol 21:3623-8. 2003
  3. ncbi Adjuvant gemcitabine and concurrent radiation for patients with resected pancreatic cancer: a phase II study
    A W Blackstock
    Department of Radiation Oncology, Wake Forest University School of Medicine, Medical Center Blvd, Winston Salem, NC 27157, USA
    Br J Cancer 95:260-5. 2006
  4. ncbi Adjuvant postoperative fluorouracil-modulated chemotherapy combined with pelvic radiation therapy for rectal cancer: initial results of intergroup 0114
    J E Tepper
    Department of Radiation Oncology, University of North Carolina at Chapel Hill, School of Medicine 27599 7512, USA
    J Clin Oncol 15:2030-9. 1997
  5. ncbi Impact of number of nodes retrieved on outcome in patients with rectal cancer
    J E Tepper
    Department of Radiation Oncology, University of North Carolina, Chapel Hill 27599 7512, USA
    J Clin Oncol 19:157-63. 2001
  6. ncbi Chemoradiation for locally advanced squamous cell carcinoma of the head and neck for organ preservation and palliation
    M E Poole
    Division of Hematology Oncology, Department of Medicine, 3009 Old Clinic Bldg, CB 7305, University of North Carolina School of Medicine, Chapel Hill, NC 25799 7305, USA
    Arch Otolaryngol Head Neck Surg 127:1446-50. 2001
  7. ncbi Adjuvant therapy in rectal cancer: analysis of stage, sex, and local control--final report of intergroup 0114
    J E Tepper
    Department of Radiation Oncology, University of North Carolina, Chapel Hill 27599 7512, USA
    J Clin Oncol 20:1744-50. 2002
  8. ncbi Adjuvant radiation therapy of patients with rectal cancer
    John Bechtel
    Department of Radiation Oncology, University of North Carolina at Chapel Hill, 27514, USA
    Clin Colorectal Cancer 2:213-22. 2003
  9. ncbi Phase II trial of hyperfractionated intensity-modulated radiation therapy and concurrent weekly cisplatin for Stage III and IVa head-and-neck cancer
    PATRICK D MAGUIRE
    Department of Radiation Oncology, New Hanover Regional Medical Center, Wilmington, NC 28401, USA
    Int J Radiat Oncol Biol Phys 79:1081-8. 2011
  10. ncbi A phase I trial of the dual farnesyltransferase and geranylgeranyltransferase inhibitor L-778,123 and radiotherapy for locally advanced pancreatic cancer
    Neil E Martin
    Department of Radiation Oncology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    Clin Cancer Res 10:5447-54. 2004

Collaborators

Detail Information

Publications19

  1. ncbi Phase III trial of trimodality therapy with cisplatin, fluorouracil, radiotherapy, and surgery compared with surgery alone for esophageal cancer: CALGB 9781
    Joel Tepper
    Department of Radiation Oncology, University of North Carolina School of Medicine, Chapel Hill, NC 27599 7512, USA
    J Clin Oncol 26:1086-92. 2008
    ..To this end, we compared survival, response, and patterns of failure of trimodality therapy to esophagectomy alone in patients with nonmetastatic esophageal cancer...
  2. ncbi Analysis of surgical salvage after failure of primary therapy in rectal cancer: results from Intergroup Study 0114
    J E Tepper
    Department of Radiation Oncology, Campus Box No 7512, University of North Carolina, Chapel Hill, NC 27599 7512, USA
    J Clin Oncol 21:3623-8. 2003
    ..A subset analysis was undertaken to investigate the prevalence and influence of salvage therapy among patients with recurrent disease...
  3. ncbi Adjuvant gemcitabine and concurrent radiation for patients with resected pancreatic cancer: a phase II study
    A W Blackstock
    Department of Radiation Oncology, Wake Forest University School of Medicine, Medical Center Blvd, Winston Salem, NC 27157, USA
    Br J Cancer 95:260-5. 2006
    ..These results confirm the feasibility of delivering adjuvant concurrent gemcitabine and radiation to the upper abdomen. This strategy produced good local regional tumour control...
  4. ncbi Adjuvant postoperative fluorouracil-modulated chemotherapy combined with pelvic radiation therapy for rectal cancer: initial results of intergroup 0114
    J E Tepper
    Department of Radiation Oncology, University of North Carolina at Chapel Hill, School of Medicine 27599 7512, USA
    J Clin Oncol 15:2030-9. 1997
    ..We attempted to determine whether the efficacy of this postoperative therapy could be improved by the addition of leucovorin and/or levamisole...
  5. ncbi Impact of number of nodes retrieved on outcome in patients with rectal cancer
    J E Tepper
    Department of Radiation Oncology, University of North Carolina, Chapel Hill 27599 7512, USA
    J Clin Oncol 19:157-63. 2001
    ..We postulated that the pathologic evaluation of the lymph nodes of surgical specimens from patients with rectal cancer can have a substantial impact on time to relapse and survival...
  6. ncbi Chemoradiation for locally advanced squamous cell carcinoma of the head and neck for organ preservation and palliation
    M E Poole
    Division of Hematology Oncology, Department of Medicine, 3009 Old Clinic Bldg, CB 7305, University of North Carolina School of Medicine, Chapel Hill, NC 25799 7305, USA
    Arch Otolaryngol Head Neck Surg 127:1446-50. 2001
    ....
  7. ncbi Adjuvant therapy in rectal cancer: analysis of stage, sex, and local control--final report of intergroup 0114
    J E Tepper
    Department of Radiation Oncology, University of North Carolina, Chapel Hill 27599 7512, USA
    J Clin Oncol 20:1744-50. 2002
    ....
  8. ncbi Adjuvant radiation therapy of patients with rectal cancer
    John Bechtel
    Department of Radiation Oncology, University of North Carolina at Chapel Hill, 27514, USA
    Clin Colorectal Cancer 2:213-22. 2003
    ..For now, we recommend that stage II and III rectal cancer patients receive protracted venous infusion 5-FU concurrent with preoperative radiation...
  9. ncbi Phase II trial of hyperfractionated intensity-modulated radiation therapy and concurrent weekly cisplatin for Stage III and IVa head-and-neck cancer
    PATRICK D MAGUIRE
    Department of Radiation Oncology, New Hanover Regional Medical Center, Wilmington, NC 28401, USA
    Int J Radiat Oncol Biol Phys 79:1081-8. 2011
    ..To investigate a novel chemoradiation regimen designed to maximize locoregional control (LRC) and minimize toxicity for patients with advanced head-and-neck squamous cell carcinoma (HNSCC)...
  10. ncbi A phase I trial of the dual farnesyltransferase and geranylgeranyltransferase inhibitor L-778,123 and radiotherapy for locally advanced pancreatic cancer
    Neil E Martin
    Department of Radiation Oncology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania, USA
    Clin Cancer Res 10:5447-54. 2004
    ..CONCLUSIONS: The combination of L-778,123 and radiotherapy at dose level 1 showed acceptable toxicity in patients with locally advanced pancreatic cancer. Radiosensitization of a patient-derived pancreatic cancer cell line was observed...
  11. ncbi Treatment recommendations for locally advanced, non-small-cell lung cancer: the influence of physician and patient factors
    Irwin H Lee
    Department of Radiation Oncology, University of Michigan, Ann Arbor, MI, USA
    Int J Radiat Oncol Biol Phys 74:1376-84. 2009
    ..To determine the impact of patient age, comorbidity, and physician factors on treatment recommendations for locally advanced, unresectable non-small-cell lung cancer (NSCLC)...
  12. ncbi Phase I trial of twice-weekly gemcitabine and concurrent radiation in patients with advanced pancreatic cancer
    A W Blackstock
    Department of Radiation Oncology, Wake Forest University Baptist Medical Center, Winston Salem, NC 27516, USA
    J Clin Oncol 17:2208-12. 1999
    ..To determine the maximum-tolerated dose, dose-limiting toxicities, and potential antitumor activity of twice-weekly gemcitabine and concurrent radiation in patients with locally advanced pancreatic cancer...
  13. ncbi Diabetes mellitus affects response to neoadjuvant chemoradiotherapy in the management of rectal cancer
    A S Caudle
    Division of Surgical Oncology, University of North Carolina, Chapel Hill, NC, USA
    Ann Surg Oncol 15:1931-6. 2008
    ..This study compares the neoadjuvant chemoradiotherapy (CRT) response in diabetic and nondiabetic patients with locally advanced rectal cancers...
  14. ncbi A Phase I trial of the farnesyltransferase inhibitor L-778,123 and radiotherapy for locally advanced lung and head and neck cancer
    Stephen M Hahn
    Department of Radiation Oncology, University of Pennsylvania School of Medicine, Philadelphia 19104 4283, USA
    Clin Cancer Res 8:1065-72. 2002
    ..The objective of this Phase I trial was to determine the maximally tolerated dose of the FTI L-778,123 in combination with radiotherapy in non-small cell lung cancer (NSCLC) and head and neck cancer (HNC)...
  15. ncbi Induction therapy for poor-prognosis anal canal carcinoma: a phase II study of the cancer and Leukemia Group B (CALGB 9281)
    Neal J Meropol
    Fox Chase Cancer Center, 333 Cottman Ave, Philadelphia, PA 19111, USA
    J Clin Oncol 26:3229-34. 2008
    ....
  16. ncbi The multidisciplinary rectal cancer treatment: main convergences, controversial aspects and investigational areas which support the need for an European Consensus
    Vincenzo Valentini
    Cattedra di Radioterapia, Universita Cattolica S Cuore, Rome, Italy
    Radiother Oncol 76:241-50. 2005
    ..Agreement between Experts, Centres, and specialists who participated in the Conference are reported...
  17. ncbi Priorities in colorectal cancer research: recommendations from the Gastrointestinal Scientific Leadership Council of the Coalition of Cancer Cooperative Groups
    PETER J O'DWYER
    Coalition of Cancer Cooperative Groups, Philadelphia, PA, USA
    J Clin Oncol 25:2313-21. 2007
    ..The implementation of biology-directed laboratory investigations, both in association with ongoing clinical trials and as a separate developmental strategy for targeted therapies, is supported as the route to individualized therapy...
  18. ncbi Gastric surgical adjuvant radiotherapy consensus report: rationale and treatment implementation
    Stephen R Smalley
    Radiation Oncology Center of Olathe, Olathe, KS 66061, USA
    Int J Radiat Oncol Biol Phys 52:283-93. 2002
    ..Supportive therapy during and after radiochemotherapy is also discussed...
  19. ncbi A model is a model: a decision analysis for rectal cancer
    Joel Tepper
    J Natl Cancer Inst 96:164-5. 2004