Research Topics
| Thomas R TenHaveSummaryAffiliation: University of Pennsylvania Country: USA Publications
Research Grants
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Detail Information
Publications
Mixed effects logistic regression models for longitudinal binary response data with informative drop-outT R Ten Have
Center for Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia 19104 6021, USA
Biometrics 54:367-83. 1998..This comparison between the data analysis and simulation results may provide evidence that the shared parameter model holds for the pain data...
Deviations from the population-averaged versus cluster-specific relationship for clustered binary dataThomas R Ten Have
Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Blockley Hall, 6th FLR, 423 Guardian Drive, Philadelphia, PA 19104 6021, USA
Stat Methods Med Res 13:3-16. 2004..Several examples, including a cross-over trial, a multicentre nonrandomized treatment study, and a longitudinal observational study are used to illustrate these modifications...
Causal logistic models for non-compliance under randomized treatment with univariate binary responseThomas R Ten Have
Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Blockley Hall, 6th FLR, 423 Guardian Dr, Philadelphia, PA 19104 6021, USA
Stat Med 22:1255-83. 2003..We also provide results from the analyses of two data sets further showing how a comparison of the marginal and conditional estimators can help evaluate the magnitude of confounding due to non-adherence...
Research to improve the quality of care for depression: alternatives to the simple randomized clinical trialThomas R TenHave
University of Pennsylvania, Medical School, Philadelphia, USA
Gen Hosp Psychiatry 25:115-23. 2003..Some of these enhancements, such as the fixed adaptive design, have begun to be implemented in effectiveness trials in mental health services research, but all are worthy of more attention...
Mixed effects logistic regression models for multiple longitudinal binary functional limitation responses with informative drop-out and confounding by baseline outcomesHaveThomasR Ten
Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia 19104 6021, USA
Biometrics 58:137-44. 2002..We also note that. under an autoregressive structure, bias results from omitting the baseline outcome component linked to the follow-up outcome component by subject-level random effects...
Mixed effects models with bivariate and univariate association parameters for longitudinal bivariate binary response dataT R Ten Have
Department of Biostatistics and Clinical Epidemiology, The University of Pennsylvania College of Medicine, Philadelphia 19104 6021, USA
Biometrics 55:85-93. 1999..The proposed model is compared to a naive bivariate model that assumes independence between time points and univariate mixed effects logit models...
Empirical Bayes estimation of random effects parameters in mixed effects logistic regression modelsT R Ten Have
Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia 19104 6021, USA
Biometrics 55:1022-9. 1999..For large cluster sizes and a few clusters, the PQL approach performs better than the KS adjustment. These simulation results agree somewhat with those of the data analyses...
Mixed effects logistic regression models for longitudinal ordinal functional response data with multiple-cause drop-out from the longitudinal study of agingT R Ten Have
Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia 19104 6021, USA
Biometrics 56:279-87. 2000..In contrast, the association between current functional limitation and previous trajectory of functional status within an individual is weaker and more sensitive to changes in the random effects and drop-out assumptions...
Causal mediation analyses with rank preserving modelsThomas R Ten Have
Department of Biostatistics and Epidemiology, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA
Biometrics 63:926-34. 2007..The trade-off between these assumptions is evaluated in the context of two suicide/depression intervention studies...
Longitudinal and repeated cross-sectional cluster-randomization designs using mixed effects regression for binary outcomes: bias and coverage of frequentist and Bayesian methodsA Russell Localio
Department of Biostatistics and Epidemiology, Center for Clinical Epidemiology and Biostatistics, School of Medicine, University of Pennsylvania, Philadelphia, PA 19104 6021, USA
Stat Med 25:2720-36. 2006..The performance of common statistical tools for the analysis of cluster randomization designs depends heavily on the precise design, the number of clusters, and the variability of baseline outcomes and treatment effects across centres...
Research Grants
- Mental Health Biostatistics Training GrantThomas Tenhave; Fiscal Year: 2007....
- Causal Methods for Mediation and InteractionThomas Tenhave; Fiscal Year: 2007..The above methods and standard mediation/interaction procedures and their assumptions will be evaluated and compared with simulations and analyses to answer the specific hypotheses from four studies of interest. ..
