N R Temkin

Summary

Affiliation: University of Washington
Country: USA

Publications

  1. doi request reprint Preventing and treating posttraumatic seizures: the human experience
    Nancy R Temkin
    Department of Neurological Surgery, University of Washington, Seattle, Washington 98104 2499, USA
    Epilepsia 50:10-3. 2009
  2. ncbi request reprint Risk factors for posttraumatic seizures in adults
    Nancy R Temkin
    Department of Neurological Surgery, University of Washington, Seattle, Washington 98104, USA
    Epilepsia 44:18-20. 2003
  3. ncbi request reprint Antiepileptogenesis and seizure prevention trials with antiepileptic drugs: meta-analysis of controlled trials
    N R Temkin
    Department of Neurological, University of Washington, Seattle 98104 2499, USA
    Epilepsia 42:515-24. 2001
  4. ncbi request reprint Standard error in the Jacobson and Truax Reliable Change Index: the "classical approach" leads to poor estimates
    Nancy R Temkin
    Departments of Neurological Surgery, Biostatistics, and Rehabilitation Medicine, University of Washington, Seattle 8104 2499, USA
    J Int Neuropsychol Soc 10:899-901; discussion 902-3. 2004
  5. ncbi request reprint Correlates of functional status 3-5 years after traumatic brain injury with CT abnormalities
    Nancy R Temkin
    Department of Neurological Surgery, University of Washington, Seattle, Washington 98104 2499, USA
    J Neurotrauma 20:229-41. 2003
  6. ncbi request reprint Magnesium sulfate for neuroprotection after traumatic brain injury: a randomised controlled trial
    Nancy R Temkin
    Department of Neurological Surgery, University of Washington, Seattle, USA
    Lancet Neurol 6:29-38. 2007
  7. ncbi request reprint Valproate therapy for prevention of posttraumatic seizures: a randomized trial
    N R Temkin
    Department of Neurological Surgery, University of Washington, Seattle 98104 2499, USA
    J Neurosurg 91:593-600. 1999
  8. ncbi request reprint Neuropsychological effects of valproate in traumatic brain injury: a randomized trial
    S S Dikmen
    Department of Rehabilitation Medicine, University of Washington, Seattle 98195 6490, USA
    Neurology 54:895-902. 2000
  9. ncbi request reprint Self-report of extent of recovery and barriers to recovery after traumatic brain injury: a longitudinal study
    J M Powell
    Department of Rehabilitation Medicine, University of Washington School of Medicine, Seattle, WA 98195 6490, USA
    Arch Phys Med Rehabil 82:1025-30. 2001
  10. doi request reprint The effect of telephone counselling on reducing post-traumatic symptoms after mild traumatic brain injury: a randomised trial
    K R Bell
    Department of Rehabilitation Medicine, University of Washington, Seattle, WA 98195, USA
    J Neurol Neurosurg Psychiatry 79:1275-81. 2008

Research Grants

Detail Information

Publications41

  1. doi request reprint Preventing and treating posttraumatic seizures: the human experience
    Nancy R Temkin
    Department of Neurological Surgery, University of Washington, Seattle, Washington 98104 2499, USA
    Epilepsia 50:10-3. 2009
    ....
  2. ncbi request reprint Risk factors for posttraumatic seizures in adults
    Nancy R Temkin
    Department of Neurological Surgery, University of Washington, Seattle, Washington 98104, USA
    Epilepsia 44:18-20. 2003
    ..This article looks at factors about the injury or individual that put people at especially high risk of developing posttraumatic seizures...
  3. ncbi request reprint Antiepileptogenesis and seizure prevention trials with antiepileptic drugs: meta-analysis of controlled trials
    N R Temkin
    Department of Neurological, University of Washington, Seattle 98104 2499, USA
    Epilepsia 42:515-24. 2001
    ..To synthesize evidence concerning the effect of antiepileptic drugs (AEDs) for seizure prevention and to contrast their effectiveness for provoked versus unprovoked seizures...
  4. ncbi request reprint Standard error in the Jacobson and Truax Reliable Change Index: the "classical approach" leads to poor estimates
    Nancy R Temkin
    Departments of Neurological Surgery, Biostatistics, and Rehabilitation Medicine, University of Washington, Seattle 8104 2499, USA
    J Int Neuropsychol Soc 10:899-901; discussion 902-3. 2004
    ..34, when the true variability due to measurement error was .014. Neuropsychologists should not use SEd in the denominator of the RCI...
  5. ncbi request reprint Correlates of functional status 3-5 years after traumatic brain injury with CT abnormalities
    Nancy R Temkin
    Department of Neurological Surgery, University of Washington, Seattle, Washington 98104 2499, USA
    J Neurotrauma 20:229-41. 2003
    ....
  6. ncbi request reprint Magnesium sulfate for neuroprotection after traumatic brain injury: a randomised controlled trial
    Nancy R Temkin
    Department of Neurological Surgery, University of Washington, Seattle, USA
    Lancet Neurol 6:29-38. 2007
    ..We aimed to test whether treatment with magnesium favourably affects outcome in head-injured patients...
  7. ncbi request reprint Valproate therapy for prevention of posttraumatic seizures: a randomized trial
    N R Temkin
    Department of Neurological Surgery, University of Washington, Seattle 98104 2499, USA
    J Neurosurg 91:593-600. 1999
    ..In this study the authors compare the safety and effectiveness of valproate with those of short-term phenytoin for prevention of seizures following traumatic brain injury...
  8. ncbi request reprint Neuropsychological effects of valproate in traumatic brain injury: a randomized trial
    S S Dikmen
    Department of Rehabilitation Medicine, University of Washington, Seattle 98195 6490, USA
    Neurology 54:895-902. 2000
    ..To examine the neuropsychological side effects of valproate (VPA) given to prevent posttraumatic seizures...
  9. ncbi request reprint Self-report of extent of recovery and barriers to recovery after traumatic brain injury: a longitudinal study
    J M Powell
    Department of Rehabilitation Medicine, University of Washington School of Medicine, Seattle, WA 98195 6490, USA
    Arch Phys Med Rehabil 82:1025-30. 2001
    ..To examine the perspective of survivors of traumatic brain injury (TBI) regarding the extent and nature of their recovery over time...
  10. doi request reprint The effect of telephone counselling on reducing post-traumatic symptoms after mild traumatic brain injury: a randomised trial
    K R Bell
    Department of Rehabilitation Medicine, University of Washington, Seattle, WA 98195, USA
    J Neurol Neurosurg Psychiatry 79:1275-81. 2008
    ..This study aimed to determine whether focused, scheduled telephone counselling during the first 3 months after MTBI decreases symptoms and improves functioning at 6 months...
  11. pmc Rates of major depressive disorder and clinical outcomes following traumatic brain injury
    Charles H Bombardier
    Department of Rehabilitation Medicine, University of Washington School of Medicine, Seattle, USA
    JAMA 303:1938-45. 2010
    ..Uncertainties exist about the rates, predictors, and outcomes of major depressive disorder (MDD) among individuals with traumatic brain injury (TBI)...
  12. ncbi request reprint Antiepileptogenic agents: how close are we?
    N R Temkin
    Department of Neurological Surgery, University of Washington, Seattle 98104 2499, USA
    Drugs 61:1045-55. 2001
    ....
  13. ncbi request reprint Workers' risk of unemployment after traumatic brain injury: a normed comparison
    J N Doctor
    Department of Medical Education and Biomedical Informatics, University of Washington School of Medicine, Seattle, Washington 98115, USA
    J Int Neuropsychol Soc 11:747-52. 2005
    ..For characteristics such as education, associated with rates of unemployment in the general population, different methods used to compare the rates may yield different results...
  14. ncbi request reprint Test-retest reliability and practice effects of expanded Halstead-Reitan Neuropsychological Test Battery
    S S Dikmen
    Department of Rehabilitation Medicine, University of Washington, Seattle 98195 6490, USA
    J Int Neuropsychol Soc 5:346-56. 1999
    ....
  15. ncbi request reprint The measurement and magnitude of awareness difficulties after traumatic brain injury: a longitudinal study
    Kathleen Farrell Pagulayan
    Department of Rehabilitation Medicine, University of Washington, Seattle, Washington 98195, USA
    J Int Neuropsychol Soc 13:561-70. 2007
    ..These results suggest that reduced self-awareness is not the norm at 1 or 12 months postinjury and highlight the need for a more standardized approach to the measurement and classification of self-awareness...
  16. ncbi request reprint Gaining insight into patients' perspectives on participation in home management activities after traumatic brain injury
    Janet M Powell
    Division of Occupational Therapy, Department of Rehabilitation Medicine, University of Washington, 1959 N E Pacific Street, Seattle, WA 98195, USA
    Am J Occup Ther 61:269-79. 2007
    ..This study investigated performance of home management activities 1 year after traumatic brain injury (TBI), as reported on the Functional Status Examination...
  17. doi request reprint Accuracy of mild traumatic brain injury diagnosis
    Janet M Powell
    Department of Rehabilitation Medicine, University of Washington, Seattle, WA 98195 6490, USA
    Arch Phys Med Rehabil 89:1550-5. 2008
    ..To determine how often emergency department (ED) patients meeting the Centers for Disease Control and Prevention (CDC) mild traumatic brain injury (TBI) criteria were diagnosed with a mild TBI by the ED physician...
  18. doi request reprint Functional limitations and depression after traumatic brain injury: examination of the temporal relationship
    Kathleen Farrell Pagulayan
    Department of Rehabilitation Medicine, University of Washington, Seattle, WA, USA
    Arch Phys Med Rehabil 89:1887-92. 2008
    ..To examine the temporal relationship between self-reported injury-related functional limitations and depressive symptomatology after traumatic brain injury (TBI)...
  19. ncbi request reprint Effect of valproate on hemostatic function in patients with traumatic brain injury
    Gail D Anderson
    Department of Pharmacy, University of Washington, Box 357630, Seattle, WA 98195, USA
    Epilepsy Res 57:111-9. 2003
    ..To evaluate whether valproate (VPA) resulted in laboratory or clinical evidence of a change in bleeding-related measures associated with VPA therapy in patients sustaining a traumatic brain injury...
  20. doi request reprint The efficacy of a scheduled telephone intervention for ameliorating depressive symptoms during the first year after traumatic brain injury
    Charles H Bombardier
    Departments of Rehabilitation Medicine, University of Washington School of Medicine, Seattle, USA
    J Head Trauma Rehabil 24:230-8. 2009
    ..To determine whether an intervention designed to improve functioning after traumatic brain injury (TBI) also ameliorates depressive symptoms...
  21. ncbi request reprint Does glucocorticoid administration prevent late seizures after head injury?
    Nathaniel F Watson
    Neurology and Sleep Disorders Center, University of Washington, Seattle, Washington 98104 2499, USA
    Epilepsia 45:690-4. 2004
    ..Preventing posttraumatic epilepsy has been a difficult challenge. In this study we evaluated the association between glucocorticoid administration after traumatic brain injury (TBI) and posttraumatic seizures...
  22. pmc Haptoglobin phenotype and apolipoprotein E polymorphism: relationship to posttraumatic seizures and neuropsychological functioning after traumatic brain injury
    Gail D Anderson
    Department of Pharmacy, University of Washington, Box 357630, Seattle, WA 98195, USA
    Epilepsy Behav 16:501-6. 2009
    ..In contrast to our hypothesis, those with haptoglobin 1-1 (high-affinity binder of hemoglobin) scored somewhat worse on Verbal IQ and Tapping D at 1 and 12 months after injury...
  23. doi request reprint Rates of symptom reporting following traumatic brain injury
    Sureyya Dikmen
    Department of Rehabilitation Medicine, University of Washington, Seattle, Washington, USA
    J Int Neuropsychol Soc 16:401-11. 2010
    ..Symptom reporting is common following a traumatic injury and continues to be experienced by a substantial number of TBI subjects of all severity levels at 1 year post-injury...
  24. ncbi request reprint Effect of time, injury, age and ethanol on interpatient variability in valproic acid pharmacokinetics after traumatic brain injury
    Gail D Anderson
    Departments of Pharmacy and Neurological Surgery, Schools of Pharmacy and Medicine corrected University of Washington, Seattle, Washington 98195, USA
    Clin Pharmacokinet 46:307-18. 2007
    ..Valproic acid is a hepatically metabolised, low extraction-ratio drug. Therefore, unbound clearance (CL(u)) is equal to intrinsic or metabolic clearance...
  25. ncbi request reprint Nonrandomized studies of rehabilitation for traumatic brain injury: can they determine effectiveness?
    Janet M Powell
    Department of Rehabilitation Medicine, University of Washington School of Medicine, Seattle, WA 98195, USA
    Arch Phys Med Rehabil 83:1235-44. 2002
    ..To examine the feasibility of investigating rehabilitation effectiveness for traumatic brain injury (TBI) with a nonrandomized design...
  26. ncbi request reprint A new and more robust test of QALYs
    Jason N Doctor
    Department of Medical Education, School of Medicine, University of Washington, 1959 N E Pacific Street, P O Box 357240, Seattle, WA 98195 6490, USA
    J Health Econ 23:353-67. 2004
    ..Our findings suggest that QALYs may be valid if nonexpected utility formulas are used to compute health state utilities...
  27. ncbi request reprint Outcome 3 to 5 years after moderate to severe traumatic brain injury
    Sureyya S Dikmen
    Department of Rehabilitation Medicine, University of Washington School Medicine, Seattle, USA
    Arch Phys Med Rehabil 84:1449-57. 2003
    ..To investigate neuropsychologic, emotional, and functional status and quality of life (QOL) 3 to 5 years after moderate to severe traumatic brain injury (TBI)...
  28. ncbi request reprint Access to inpatient rehabilitation after violence-related traumatic brain injury
    Peter C Esselman
    Department of Rehabilitation Medicine, University of Washington, Seattle, USA
    Arch Phys Med Rehabil 85:1445-9. 2004
    ..To examine injury characteristics, demographics, and discharge disposition after traumatic brain injury of violent or nonviolent cause...
  29. ncbi request reprint Natural history of depression in traumatic brain injury
    Sureyya S Dikmen
    Department of Rehabilitation Medicine, University of Washington, Seattle 98195, USA
    Arch Phys Med Rehabil 85:1457-64. 2004
    ..To examine prospectively the rates, risk factors, and phenomenology of depression over 3 to 5 years after traumatic brain injury (TBI)...
  30. ncbi request reprint The effect of a scheduled telephone intervention on outcome after moderate to severe traumatic brain injury: a randomized trial
    Kathleen R Bell
    Department of Rehabilitation Medicine, University of Washington, Seattle, WA, USA
    Arch Phys Med Rehabil 86:851-6. 2005
    ..To measure the effectiveness of a scheduled telephone intervention offering counseling and education to people with traumatic brain injury (TBI) on behavioral outcomes compared with standard follow-up at 1 year postinjury...
  31. ncbi request reprint The natural history of drinking and alcohol-related problems after traumatic brain injury
    Charles H Bombardier
    Department of Rehabilitation Medicine, University of Washington School of Medicine, Seattle, WA, USA
    Arch Phys Med Rehabil 84:185-91. 2003
    ..To describe changes in drinking from before traumatic brain injury (TBI) to 1 year after TBI...
  32. doi request reprint Depression treatment preferences after traumatic brain injury
    Jesse R Fann
    Departments of Psychiatry and Behavioral Sciences, School of Public Health and Community Medicine, University of Washington, Seattle, USA
    J Head Trauma Rehabil 24:272-8. 2009
    ..To determine preferences for depression treatment modalities and settings among persons with traumatic brain injury (TBI)...
  33. ncbi request reprint A longitudinal study of health-related quality of life after traumatic brain injury
    Kathleen F Pagulayan
    Department of Rehabilitation Medicine, University of Washington, Seattle, WA 98195, USA
    Arch Phys Med Rehabil 87:611-8. 2006
    ..To examine the longitudinal course of health-related quality of life from 1 month to 3 to 5 years after traumatic brain injury (TBI)...
  34. ncbi request reprint Utility of a composite measure to detect problematic alcohol use in persons with traumatic brain injury
    M Cherner
    Department of Rehabilitation Medicine, University of Washington School of Medicine, Seattle, WA 98195-6490, USA
    Arch Phys Med Rehabil 82:780-6. 2001
    ..CONCLUSION: The composite index is useful in identifying problematic drinkers among TBI patients. Results have implications for interpreting and planning research on the role of alcohol in TBI outcomes...
  35. ncbi request reprint Neurobehavioral outcome in persons with violent or nonviolent traumatic brain injury
    Joan E Machamer
    Department of Rehabilitation Medicine, University of Washington, Seattle, WA, USA
    J Head Trauma Rehabil 18:387-97. 2003
    ..To broaden the investigation of those injured violently by examining neuropsychological and psychosocial outcomes in relation to circumstances of traumatic brain injury and preinjury factors...
  36. pmc ECoG studies of valproate, carbamazepine and halothane in frontal-lobe epilepsy induced by head injury in the rat
    Clifford L Eastman
    Department of Neurological Surgery, University of Washington, School of Medicine, Seattle, WA 98104, USA
    Exp Neurol 224:369-88. 2010
    ..The data also demonstrate the utility of chronic exposures to experimental drugs in preclinical studies and highlight the need for greater attention to etiology in clinical studies of AEDs...
  37. doi request reprint Social functioning after traumatic brain injury
    Nancy R Temkin
    Departments of Neurological Surgery and Biostatistics, University of Washington, Seattle, WA 98104, USA
    J Head Trauma Rehabil 24:460-7. 2009
    ....
  38. doi request reprint Participant recruitment and retention in rehabilitation research
    Kathleen R Bell
    Department of Rehabilitation Medicine, University of Washington, Seattle, Washington 98195, USA
    Am J Phys Med Rehabil 87:330-8. 2008
  39. ncbi request reprint Functional outcome scales in traumatic brain injury: a comparison of the Glasgow Outcome Scale (Extended) and the Functional Status Examination
    Anne M Hudak
    Department of Physical Medicine and Rehabilitation, University of Texas Southwestern Medical Center, Dallas, Texas 75390 9055, USA
    J Neurotrauma 22:1319-26. 2005
    ..The majority of the variance in outcome is not accounted for by currently available measures of injury severity...
  40. ncbi request reprint Timing of surgery after multisystem injury with traumatic brain injury: effect on neuropsychological and functional outcome
    Marjorie C Wang
    Department of Neurosurgery, Medical College ofWisconsin, Milwaukee 53226, USA
    J Trauma 62:1250-8. 2007
    ..We sought to determine whether 6-month neuropsychological and functional outcome was associated with timing of noncranial surgery after traumatic brain injury...
  41. ncbi request reprint Magnesium for neuroprotection after traumatic brain injury
    H Richard Winn
    Lancet Neurol 6:478-9. 2007

Research Grants4

  1. MAGNESIUM SULFATE FOR NEUROPROTECTION AFTER BRAIN TRAUMA
    Nancy Temkin; Fiscal Year: 2004
    ..abstract_text> ..
  2. Traumatic Brain Injury Clinical Trials Network
    Nancy Temkin; Fiscal Year: 2006
    ..Additionally, the study will assess the effects of timing of dosage (e.g. <4 hours vs. 4-8 hours), gender, and race, and determine the rate of adverse events. ..