Inna E Tchivileva
Affiliation: University of North Carolina
- Characterization of NF-kB-mediated inhibition of catechol-O-methyltransferaseInna E Tchivileva
Center for Neurosensory Disorders, School of Dentistry, University of North Carolina, Chapel Hill, NC 27599 7455, USA
Mol Pain 5:13. 2009..Specifically, low COMT activity is associated with heightened pain perception and development of musculoskeletal pain in humans as well as increased experimental pain sensitivity in rodents...
- Signaling pathways mediating beta3-adrenergic receptor-induced production of interleukin-6 in adipocytesInna E Tchivileva
The Center for Neurosensory Disorders, School of Dentistry, University of North Carolina, Chapel Hill, NC 27599, USA
Mol Immunol 46:2256-66. 2009....
- Effect of catechol-O-methyltransferase polymorphism on response to propranolol therapy in chronic musculoskeletal pain: a randomized, double-blind, placebo-controlled, crossover pilot studyInna E Tchivileva
Center for Neurosensory Disorders, School of Dentistry, University of North Carolina, Chapel Hill, NC 27599 7450, USA
Pharmacogenet Genomics 20:239-48. 2010..We hypothesized that the nonselective beta-adrenergic antagonist propranolol will reduce clinical and experimental pain in TMD patients in a manner dependent on the individuals' COMT diplotype...
- Genetic architecture of human pain perceptionLuda Diatchenko
Center for Neurosensory Disorders, University of North Carolina, 2190 Old Dental Building, Chapel Hill, NC 27599, USA
Trends Genet 23:605-13. 2007..We propose how both rare deleterious genetic variants and common genetic polymorphisms are mediators of human pain perception and clinical pain phenotypes...